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Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.

Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, Kim J, Powers J, Gracia-Hernandez M, Oliveira V, Cheng F, Chen J, Barinka C, Pinilla-Ibarz J, Lee NH, Kozikowski A, Villagra A.

Sci Rep. 2019 Oct 10;9(1):14824. doi: 10.1038/s41598-019-51403-6.


Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.

Shen S, Hadley M, Ustinova K, Pavlicek J, Knox T, Noonepalle S, Tavares MT, Zimprich CA, Zhang G, Robers MB, Bařinka C, Kozikowski AP, Villagra A.

J Med Chem. 2019 Sep 26;62(18):8557-8577. doi: 10.1021/acs.jmedchem.9b00946. Epub 2019 Sep 4.


A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance.

Olender J, Wang BD, Ching T, Garmire LX, Garofano K, Ji Y, Knox T, Latham P, Nguyen K, Rhim J, Lee NH.

Mol Cancer Res. 2019 Oct;17(10):2115-2125. doi: 10.1158/1541-7786.MCR-19-0415. Epub 2019 Jul 2.


Alterations in brain neurocircuitry following treatment with the chemotherapeutic agent paclitaxel in rats.

Ferris CF, Nodine S, Pottala T, Cai X, Knox TM, Fofana FH, Kim S, Kulkarni P, Crystal JD, Hohmann AG.

Neurobiol Pain. 2019 May 27;6:100034. doi: 10.1016/j.ynpai.2019.100034. eCollection 2019 Aug-Dec.


Transwomen in elite sport: scientific and ethical considerations.

Knox T, Anderson LC, Heather A.

J Med Ethics. 2019 Jun;45(6):395-403. doi: 10.1136/medethics-2018-105208. Epub 2019 Jun 19.


Patterns of anopheline feeding/resting behaviour and Plasmodium infections in North Cameroon, 2011-2014: implications for malaria control.

Ekoko WE, Awono-Ambene P, Bigoga J, Mandeng S, Piameu M, Nvondo N, Toto JC, Nwane P, Patchoke S, Mbakop LR, Binyang JA, Donelly M, Kleinschmidt I, Knox T, Mbida AM, Dongmo A, Fondjo E, Mnzava A, Etang J.

Parasit Vectors. 2019 Jun 13;12(1):297. doi: 10.1186/s13071-019-3552-2.


Case Definitions of Clinical Malaria in Children from Three Health Districts in the North Region of Cameroon.

Tabue RN, Njeambosay BA, Zeukeng F, Esemu LF, Fodjo BAY, Nyonglema P, Awono-Ambene P, Etang J, Fondjo E, Achu D, Leke RGF, Kouambeng C, Knox TB, Mnzava AP, Bigoga JD.

Biomed Res Int. 2019 Apr 16;2019:9709013. doi: 10.1155/2019/9709013. eCollection 2019.


Strengthening of vector control in South-East Asia: Outcomes from a WHO regional workshop.

Nagpal BN, Knox TB, Risintha P, Yadav RS, Ghosh SK, Uragayala S, Valecha N, Christophel EM, Jamsheed M.

J Vector Borne Dis. 2018 Oct-Dec;55(4):247-257. doi: 10.4103/0972-9062.256559. No abstract available.


Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.

Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, Kim J, Powers J, Gracia-Hernandez M, Oliveira V, Cheng F, Chen J, Barinka C, Pinilla-Ibarz J, Lee NH, Kozikowski A, Villagra A.

Sci Rep. 2019 Apr 16;9(1):6136. doi: 10.1038/s41598-019-42237-3. Erratum in: Sci Rep. 2019 Oct 10;9(1):14824.


Spatial and temporal development of deltamethrin resistance in malaria vectors of the Anopheles gambiae complex from North Cameroon.

Mandeng SE, Awono-Ambene HP, Bigoga JD, Ekoko WE, Binyang J, Piameu M, Mbakop LR, Fesuh BN, Mvondo N, Tabue R, Nwane P, Mimpfoundi R, Toto JC, Kleinschmidt I, Knox TB, Mnzava AP, Donnelly MJ, Fondjo E, Etang J.

PLoS One. 2019 Feb 19;14(2):e0212024. doi: 10.1371/journal.pone.0212024. eCollection 2019.


Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: evidence from health facility data from Benin.

Tokponnon FT, Sissinto Y, Ogouyémi AH, Adéothy AA, Adechoubou A, Houansou T, Oke M, Kinde-Gazard D, Massougbodji A, Akogbeto MC, Cornelie S, Corbel V, Knox TB, Mnzava AP, Donnelly MJ, Kleinschmidt I, Bradley J.

Malar J. 2019 Feb 11;18(1):37. doi: 10.1186/s12936-019-2656-7.


In search of early neuroradiological biomarkers for Parkinson's Disease: Alterations in resting state functional connectivity and gray matter microarchitecture in PINK1 -/- rats.

Cai X, Qiao J, Knox T, Iriah S, Kulkarni P, Madularu D, Morrison T, Waszczak B, Hartner JC, Ferris CF.

Brain Res. 2019 Mar 1;1706:58-67. doi: 10.1016/j.brainres.2018.10.033. Epub 2018 Oct 31.


A Perspective on the Baltimore Freddie Gray Riots: Turning Tragedy Into Civic Engagement and Culture Change in an Academic Department of Medicine.

Golden SH, Cudjoe TKM, Galiatsatos P, Brownlee D, Flanagan E, Crews DC, Maruthur N, Brown M, Ashby A, Hellmann DB, Knox T, Anderson ME.

Acad Med. 2018 Dec;93(12):1808-1813. doi: 10.1097/ACM.0000000000002389.


The Burden of Untreated HCV Infection in Hospitalized Inmates: a Hospital Utilization and Cost Analysis.

Wurcel AG, Burke DJ, Wang JJ, Engle B, Noonan K, Knox TA, Kim AY, Linas BP.

J Urban Health. 2018 Aug;95(4):467-473. doi: 10.1007/s11524-018-0277-z.


The bionomics of the malaria vector Anopheles rufipes Gough, 1910 and its susceptibility to deltamethrin insecticide in North Cameroon.

Awono-Ambene PH, Etang J, Antonio-Nkondjio C, Ndo C, Eyisap WE, Piameu MC, Mandeng ES, Mbakop RL, Toto JC, Patchoke S, Mnzava AP, Knox TB, Donnelly M, Fondjo E, D Bigoga J.

Parasit Vectors. 2018 Apr 18;11(1):253. doi: 10.1186/s13071-018-2809-5.


Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: a WHO-coordinated, prospective, international, observational cohort study.

Kleinschmidt I, Bradley J, Knox TB, Mnzava AP, Kafy HT, Mbogo C, Ismail BA, Bigoga JD, Adechoubou A, Raghavendra K, Cook J, Malik EM, Nkuni ZJ, Macdonald M, Bayoh N, Ochomo E, Fondjo E, Awono-Ambene HP, Etang J, Akogbeto M, Bhatt RM, Chourasia MK, Swain DK, Kinyari T, Subramaniam K, Massougbodji A, Okê-Sopoh M, Ogouyemi-Hounto A, Kouambeng C, Abdin MS, West P, Elmardi K, Cornelie S, Corbel V, Valecha N, Mathenge E, Kamau L, Lines J, Donnelly MJ.

Lancet Infect Dis. 2018 Jun;18(6):640-649. doi: 10.1016/S1473-3099(18)30172-5. Epub 2018 Apr 9.


Temporal and spatial trends in insecticide resistance in Anopheles arabiensis in Sudan: outcomes from an evaluation of implications of insecticide resistance for malaria vector control.

Ismail BA, Kafy HT, Sulieman JE, Subramaniam K, Thomas B, Mnzava A, Abu Kassim NF, Ahmad AH, Knox TB, Kleinschmidt I, Donnelly MJ.

Parasit Vectors. 2018 Mar 2;11(1):122. doi: 10.1186/s13071-018-2732-9.


Spore forming bacteria infections and people who inject drugs: Implications for harm reduction.

Dunleavy K, Munro A, Roy K, Hutchinson S, Palmateer N, Knox T, Goldberg D, Hope V, Campbell J, Hamilton E, Liddell D, Penrice G, Taylor A.

Int J Drug Policy. 2018 Mar;53:45-54. doi: 10.1016/j.drugpo.2017.12.001. Epub 2017 Dec 24.


Impact of insecticide resistance in Anopheles arabiensis on malaria incidence and prevalence in Sudan and the costs of mitigation.

Kafy HT, Ismail BA, Mnzava AP, Lines J, Abdin MSE, Eltaher JS, Banaga AO, West P, Bradley J, Cook J, Thomas B, Subramaniam K, Hemingway J, Knox TB, Malik EM, Yukich JO, Donnelly MJ, Kleinschmidt I.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11267-E11275. doi: 10.1073/pnas.1713814114. Epub 2017 Dec 11.


Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models.

Tavares MT, Shen S, Knox T, Hadley M, Kutil Z, Bařinka C, Villagra A, Kozikowski AP.

ACS Med Chem Lett. 2017 Sep 5;8(10):1031-1036. doi: 10.1021/acsmedchemlett.7b00223. eCollection 2017 Oct 12.


"Tweak Your Order Set!" Implementation of Modified Laboratory Order Set Improves Hepatitis C Virus Screening Rates in People Living With Human Immunodeficiency Virus.

Wurcel AG, Chen DD, Chui KKH, Knox TA.

Open Forum Infect Dis. 2017 May 16;4(2):ofx098. doi: 10.1093/ofid/ofx098. eCollection 2017 Spring.


Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin.

Bradley J, Ogouyèmi-Hounto A, Cornélie S, Fassinou J, de Tove YSS, Adéothy AA, Tokponnon FT, Makoutode P, Adechoubou A, Legba T, Houansou T, Kinde-Gazard D, Akogbeto MC, Massougbodji A, Knox TB, Donnelly M, Kleinschmidt I.

Malar J. 2017 May 26;16(1):225. doi: 10.1186/s12936-017-1873-1.


Insecticide-Treated Nets and Protection against Insecticide-Resistant Malaria Vectors in Western Kenya.

Ochomo E, Chahilu M, Cook J, Kinyari T, Bayoh NM, West P, Kamau L, Osangale A, Ombok M, Njagi K, Mathenge E, Muthami L, Subramaniam K, Knox T, Mnavaza A, Donnelly MJ, Kleinschmidt I, Mbogo C.

Emerg Infect Dis. 2017 May;23(5):758-764. doi: 10.3201/eid2305.161315.


Association between harm reduction intervention uptake and skin and soft tissue infections among people who inject drugs.

Dunleavy K, Munro A, Roy K, Hutchinson S, Palmateer N, Knox T, Goldberg D, Taylor A.

Drug Alcohol Depend. 2017 May 1;174:91-97. doi: 10.1016/j.drugalcdep.2017.01.020. Epub 2017 Mar 6.


Impact of long-lasting insecticidal nets on prevalence of subclinical malaria among children in the presence of pyrethroid resistance in Anopheles culicifacies in Central India.

Chourasia MK, Kamaraju R, Kleinschmidt I, Bhatt RM, Swain DK, Knox TB, Valecha N.

Int J Infect Dis. 2017 Apr;57:123-129. doi: 10.1016/j.ijid.2017.02.001. Epub 2017 Mar 6.


Role of Anopheles (Cellia) rufipes (Gough, 1910) and other local anophelines in human malaria transmission in the northern savannah of Cameroon: a cross-sectional survey.

Tabue RN, Awono-Ambene P, Etang J, Atangana J, C AN, Toto JC, Patchoke S, Leke RG, Fondjo E, Mnzava AP, Knox TB, Tougordi A, Donnelly MJ, Bigoga JD.

Parasit Vectors. 2017 Jan 11;10(1):22. doi: 10.1186/s13071-016-1933-3.


Increasing Infectious Endocarditis Admissions Among Young People Who Inject Drugs.

Wurcel AG, Anderson JE, Chui KK, Skinner S, Knox TA, Snydman DR, Stopka TJ.

Open Forum Infect Dis. 2016 Jul 26;3(3):ofw157. eCollection 2016 Sep.


Erratum to: Functional Analysis of Histone Deacetylase 11 (HDAC11).

Chen J, Sahakian E, Powers J, Lienlaf M, Perez-Villarroel P, Knox T, Villagra A.

Methods Mol Biol. 2016;1436:E1. No abstract available.


Malaria: Global progress 2000 - 2015 and future challenges.

Cibulskis RE, Alonso P, Aponte J, Aregawi M, Barrette A, Bergeron L, Fergus CA, Knox T, Lynch M, Patouillard E, Schwarte S, Stewart S, Williams R.

Infect Dis Poverty. 2016 Jun 9;5(1):61. doi: 10.1186/s40249-016-0151-8.


Functional Analysis of Histone Deacetylase 11 (HDAC11).

Chen J, Sahakian E, Powers J, Lienlaf M, Perez-Villarroel P, Knox T, Villagra A.

Methods Mol Biol. 2016;1436:147-65. doi: 10.1007/978-1-4939-3667-0_11.


Expression and Function of Histone Deacetylase 10 (HDAC10) in B Cell Malignancies.

Powers J, Lienlaf M, Perez-Villarroel P, Deng S, Knox T, Villagra A, Sahakian E.

Methods Mol Biol. 2016;1436:129-45. doi: 10.1007/978-1-4939-3667-0_10.


Hepatitis C Screening in People With Human Immunodeficiency Virus: Lessons Learned From Syphilis Screening.

Wurcel AG, Chen DD, Fitzpatrick RE, Grasberger PE, Kirshner CH, Anderson JE, Chui KK, Knox TA.

Open Forum Infect Dis. 2016 Feb 12;3(1):ofv215. doi: 10.1093/ofid/ofv215. eCollection 2016 Jan.


Essential role of HDAC6 in the regulation of PD-L1 in melanoma.

M L, P PV, T K, M P, E S, J P, K V W, C L, F C, S D, M SKS, M M, A K, J PI, A S, E S, J W, E M S, A V.

Mol Oncol. 2016 May;10(5):735-750. doi: 10.1016/j.molonc.2015.12.012. Epub 2016 Jan 6.


Cholesterol Levels in HIV- and/or HCV-Infected Drug Users Living in Argentina.

Kohli R, Winston D, Sheehan H, Muzzio E, Benetucci J, Weissenbacher M, Wanke C, Knox T, Tang A.

J Int Assoc Provid AIDS Care. 2016 Sep;15(5):400-5. doi: 10.1177/2325957415614650. Epub 2015 Oct 30.


Diving deeper into individual foraging specializations of a large marine predator, the southern sea lion.

Baylis AM, Orben RA, Arnould JP, Peters K, Knox T, Costa DP, Staniland IJ.

Oecologia. 2015 Dec;179(4):1053-65. doi: 10.1007/s00442-015-3421-4. Epub 2015 Sep 1.


Sexual Niche Segregation and Gender-Specific Individual Specialisation in a Highly Dimorphic Marine Mammal.

Kernaléguen L, Cherel Y, Knox TC, Baylis AM, Arnould JP.

PLoS One. 2015 Aug 5;10(8):e0133018. doi: 10.1371/journal.pone.0133018. eCollection 2015.


Design of a study to determine the impact of insecticide resistance on malaria vector control: a multi-country investigation.

Kleinschmidt I, Mnzava AP, Kafy HT, Mbogo C, Bashir AI, Bigoga J, Adechoubou A, Raghavendra K, Knox TB, Malik EM, Nkuni ZJ, Bayoh N, Ochomo E, Fondjo E, Kouambeng C, Awono-Ambene HP, Etang J, Akogbeto M, Bhatt R, Swain DK, Kinyari T, Njagi K, Muthami L, Subramaniam K, Bradley J, West P, Massougbodji A, Okê-Sopoh M, Hounto A, Elmardi K, Valecha N, Kamau L, Mathenge E, Donnelly MJ.

Malar J. 2015 Jul 22;14:282. doi: 10.1186/s12936-015-0782-4.


Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.

Woan KV, Lienlaf M, Perez-Villaroel P, Lee C, Cheng F, Knox T, Woods DM, Barrios K, Powers J, Sahakian E, Wang HW, Canales J, Marante D, Smalley KSM, Bergman J, Seto E, Kozikowski A, Pinilla-Ibarz J, Sarnaik A, Celis E, Weber J, Sotomayor EM, Villagra A.

Mol Oncol. 2015 Aug;9(7):1447-1457. doi: 10.1016/j.molonc.2015.04.002. Epub 2015 Apr 24.


Implementation of the global plan for insecticide resistance management in malaria vectors: progress, challenges and the way forward.

Mnzava AP, Knox TB, Temu EA, Trett A, Fornadel C, Hemingway J, Renshaw M.

Malar J. 2015 Apr 23;14:173. doi: 10.1186/s12936-015-0693-4. Review.


Malaria vector control at a crossroads: public health entomology and the drive to elimination.

Mnzava AP, Macdonald MB, Knox TB, Temu EA, Shiff CJ.

Trans R Soc Trop Med Hyg. 2014 Sep;108(9):550-4. doi: 10.1093/trstmh/tru101. Epub 2014 Jul 9. Review.


Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells.

Cheng F, Lienlaf M, Perez-Villarroel P, Wang HW, Lee C, Woan K, Woods D, Knox T, Bergman J, Pinilla-Ibarz J, Kozikowski A, Seto E, Sotomayor EM, Villagra A.

Mol Immunol. 2014 Jul;60(1):44-53. doi: 10.1016/j.molimm.2014.02.019. Epub 2014 Apr 18.


An online tool for mapping insecticide resistance in major Anopheles vectors of human malaria parasites and review of resistance status for the Afrotropical region.

Knox TB, Juma EO, Ochomo EO, Pates Jamet H, Ndungo L, Chege P, Bayoh NM, N'Guessan R, Christian RN, Hunt RH, Coetzee M.

Parasit Vectors. 2014 Feb 21;7:76. doi: 10.1186/1756-3305-7-76.


Novel septin 9 repeat motifs altered in neuralgic amyotrophy bind and bundle microtubules.

Bai X, Bowen JR, Knox TK, Zhou K, Pendziwiat M, Kuhlenbäumer G, Sindelar CV, Spiliotis ET.

J Cell Biol. 2013 Dec 23;203(6):895-905.


Synergist bioassays: A simple method for initial metabolic resistance investigation of field Anopheles gambiae s.l. populations.

Chouaïbou M, Zivanovic GB, Knox TB, Jamet HP, Bonfoh B.

Acta Trop. 2014 Feb;130:108-11. doi: 10.1016/j.actatropica.2013.10.020. Epub 2013 Nov 2.


Metabolic syndrome predicts all-cause mortality in persons with human immunodeficiency virus.

Jarrett OD, Wanke CA, Ruthazer R, Bica I, Isaac R, Knox TA.

AIDS Patient Care STDS. 2013 May;27(5):266-71. doi: 10.1089/apc.2012.0402.


Increase in susceptibility to insecticides with aging of wild Anopheles gambiae mosquitoes from Côte d'Ivoire.

Chouaibou MS, Chabi J, Bingham GV, Knox TB, N'dri L, Kesse NB, Bonfoh B, Jamet HV.

BMC Infect Dis. 2012 Sep 13;12:214. doi: 10.1186/1471-2334-12-214.


Mining for future health care providers in Appalachian Kentucky.

Gross DA, Bates P, Knox TL, Gayheart MW.

J Health Care Poor Underserved. 2012 May;23(2):694-704. doi: 10.1353/hpu.2012.0068.


The association of HIV viral load with indirect markers of liver injury.

Forrester JE, Rhee MS, McGovern BH, Sterling RK, Knox TA, Terrin N.

J Viral Hepat. 2012 Feb;19(2):e202-11. doi: 10.1111/j.1365-2893.2011.01529.x. Epub 2011 Dec 2.


Practical aspects of oronasopharyngeal suction in children.

Knox T.

Nurs Child Young People. 2011 Sep;23(7):14-7.


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