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Items: 1 to 50 of 548

1.

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.

Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.

J Clin Invest. 2018 Nov 1;128(11):5185. doi: 10.1172/JCI124649. Epub 2018 Nov 1. No abstract available.

2.

High density genetic mapping of Fusarium head blight resistance QTL in tetraploid wheat.

Sari E, Berraies S, Knox RE, Singh AK, Ruan Y, Cuthbert RD, Pozniak CJ, Henriquez MA, Kumar S, Burt AJ, N'Diaye A, Konkin DJ, Cabral AL, Campbell HL, Wiebe K, Condie J, Lokuruge P, Meyer B, Fedak G, Clarke FR, Clarke JM, Somers DJ, Fobert PR.

PLoS One. 2018 Oct 11;13(10):e0204362. doi: 10.1371/journal.pone.0204362. eCollection 2018.

3.

Genetic analysis of resistance to stripe rust in durum wheat (Triticum turgidum L. var. durum).

Lin X, N'Diaye A, Walkowiak S, Nilsen KT, Cory AT, Haile J, Kutcher HR, Ammar K, Loladze A, Huerta-Espino J, Clarke JM, Ruan Y, Knox R, Fobert P, Sharpe AG, Pozniak CJ.

PLoS One. 2018 Sep 19;13(9):e0203283. doi: 10.1371/journal.pone.0203283. eCollection 2018.

4.

In memory of Thomas Turpin Bannister (1930-2018).

Laws E, Weidemann A, Hoch G, Bannister H, Knox RS, Govindjee.

Photosynth Res. 2018 Nov;138(2):129-138. doi: 10.1007/s11120-018-0582-0. Epub 2018 Sep 15.

PMID:
30219942
5.

Shifting the limits in wheat research and breeding using a fully annotated reference genome.

International Wheat Genome Sequencing Consortium (IWGSC); IWGSC RefSeq principal investigators:, Appels R, Eversole K, Feuillet C, Keller B, Rogers J, Stein N; IWGSC whole-genome assembly principal investigators:, Pozniak CJ, Stein N, Choulet F, Distelfeld A, Eversole K, Poland J, Rogers J, Ronen G, Sharpe AG; Whole-genome sequencing and assembly:, Pozniak C, Ronen G, Stein N, Barad O, Baruch K, Choulet F, Keeble-Gagnère G, Mascher M, Sharpe AG, Ben-Zvi G, Josselin AA; Hi-C data-based scaffolding:, Stein N, Mascher M, Himmelbach A; Whole-genome assembly quality control and analyses:, Choulet F, Keeble-Gagnère G, Mascher M, Rogers J, Balfourier F, Gutierrez-Gonzalez J, Hayden M, Josselin AA, Koh C, Muehlbauer G, Pasam RK, Paux E, Pozniak CJ, Rigault P, Sharpe AG, Tibbits J, Tiwari V; Pseudomolecule assembly:, Choulet F, Keeble-Gagnère G, Mascher M, Josselin AA, Rogers J; RefSeq genome structure and gene analyses:, Spannagl M, Choulet F, Lang D, Gundlach H, Haberer G, Keeble-Gagnère G, Mayer KFX, Ormanbekova D, Paux E, Prade V, Šimková H, Wicker T; Automated annotation:, Choulet F, Spannagl M, Swarbreck D, Rimbert H, Felder M, Guilhot N, Gundlach H, Haberer G, Kaithakottil G, Keilwagen J, Lang D, Leroy P, Lux T, Mayer KFX, Twardziok S, Venturini L; Manual gene curation:, Appels R, Rimbert H, Choulet F, Juhász A, Keeble-Gagnère G; Subgenome comparative analyses:, Choulet F, Spannagl M, Lang D, Abrouk M, Haberer G, Keeble-Gagnère G, Mayer KFX, Wicker T; Transposable elements:, Choulet F, Wicker T, Gundlach H, Lang D, Spannagl M; Phylogenomic analyses:, Lang D, Spannagl M, Appels R, Fischer I; Transcriptome analyses and RNA-seq data:, Uauy C, Borrill P, Ramirez-Gonzalez RH, Appels R, Arnaud D, Chalabi S, Chalhoub B, Choulet F, Cory A, Datla R, Davey MW, Hayden M, Jacobs J, Lang D, Robinson SJ, Spannagl M, Steuernagel B, Tibbits J, Tiwari V, van Ex F, Wulff BBH; Whole-genome methylome:, Pozniak CJ, Robinson SJ, Sharpe AG, Cory A; Histone mark analyses:, Benhamed M, Paux E, Bendahmane A, Concia L, Latrasse D; BAC chromosome MTP IWGSC–Bayer Whole-Genome Profiling (WGP) tags:, Rogers J, Jacobs J, Alaux M, Appels R, Bartoš J, Bellec A, Berges H, Doležel J, Feuillet C, Frenkel Z, Gill B, Korol A, Letellier T, Olsen OA, Šimková H, Singh K, Valárik M, van der Vossen E, Vautrin S, Weining S; Chromosome LTC mapping and physical mapping quality control:, Korol A, Frenkel Z, Fahima T, Glikson V, Raats D, Rogers J; RH mapping:, Tiwari V, Gill B, Paux E, Poland J; Optical mapping:, Doležel J, Číhalíková J, Šimková H, Toegelová H, Vrána J; Recombination analyses:, Sourdille P, Darrier B; Gene family analyses:, Appels R, Spannagl M, Lang D, Fischer I, Ormanbekova D, Prade V; CBF gene family:, Barabaschi D, Cattivelli L; Dehydrin gene family:, Hernandez P, Galvez S, Budak H; NLR gene family:, Steuernagel B, Jones JDG, Witek K, Wulff BBH, Yu G; PPR gene family:, Small I, Melonek J, Zhou R; Prolamin gene family:, Juhász A, Belova T, Appels R, Olsen OA; WAK gene family:, Kanyuka K, King R; Stem solidness (SSt1) QTL team:, Nilsen K, Walkowiak S, Pozniak CJ, Cuthbert R, Datla R, Knox R, Wiebe K, Xiang D; Flowering locus C (FLC) gene team:, Rohde A, Golds T; Genome size analysis:, Doležel J, Čížková J, Tibbits J; MicroRNA and tRNA annotation:, Budak H, Akpinar BA, Biyiklioglu S; Genetic maps and mapping:, Muehlbauer G, Poland J, Gao L, Gutierrez-Gonzalez J, N'Daiye A; BAC libraries and chromosome sorting:, Doležel J, Šimková H, Číhalíková J, Kubaláková M, Šafář J, Vrána J; BAC pooling, BAC library repository, and access:, Berges H, Bellec A, Vautrin S; IWGSC sequence and data repository and access:, Alaux M, Alfama F, Adam-Blondon AF, Flores R, Guerche C, Letellier T, Loaec M, Quesneville H; Physical maps and BAC-based sequences:; 1A BAC sequencing and assembly:, Pozniak CJ, Sharpe AG, Walkowiak S, Budak H, Condie J, Ens J, Koh C, Maclachlan R, Tan Y, Wicker T; 1B BAC sequencing and assembly:, Choulet F, Paux E, Alberti A, Aury JM, Balfourier F, Barbe V, Couloux A, Cruaud C, Labadie K, Mangenot S, Wincker P; 1D, 4D, and 6D physical mapping:, Gill B, Kaur G, Luo M, Sehgal S; 2AL physical mapping:, Singh K, Chhuneja P, Gupta OP, Jindal S, Kaur P, Malik P, Sharma P, Yadav B; 2AS physical mapping:, Singh NK, Khurana J, Chaudhary C, Khurana P, Kumar V, Mahato A, Mathur S, Sevanthi A, Sharma N, Tomar RS; 2B, 2D, 4B, 5BL, and 5DL IWGSC–Bayer Whole-Genome Profiling (WGP) physical maps:, Rogers J, Jacobs J, Alaux M, Bellec A, Berges H, Doležel J, Feuillet C, Frenkel Z, Gill B, Korol A, van der Vossen E, Vautrin S; 3AL physical mapping:, Gill B, Kaur G, Luo M, Sehgal S; 3DS physical mapping and BAC sequencing and assembly:, Bartoš J, Holušová K, Plíhal O; 3DL BAC sequencing and assembly:, Clark MD, Heavens D, Kettleborough G, Wright J; 4A physical mapping, BAC sequencing, assembly, and annotation:, Valárik M, Abrouk M, Balcárková B, Holušová K, Hu Y, Luo M; 5BS BAC sequencing and assembly:, Salina E, Ravin N, Skryabin K, Beletsky A, Kadnikov V, Mardanov A, Nesterov M, Rakitin A, Sergeeva E; 6B BAC sequencing and assembly:, Handa H, Kanamori H, Katagiri S, Kobayashi F, Nasuda S, Tanaka T, Wu J; 7A physical mapping and BAC sequencing:, Appels R, Hayden M, Keeble-Gagnère G, Rigault P, Tibbits J; 7B physical mapping, BAC sequencing, and assembly:, Olsen OA, Belova T, Cattonaro F, Jiumeng M, Kugler K, Mayer KFX, Pfeifer M, Sandve S, Xun X, Zhan B; 7DS BAC sequencing and assembly:, Šimková H, Abrouk M, Batley J, Bayer PE, Edwards D, Hayashi S, Toegelová H, Tulpová Z, Visendi P; 7DL physical mapping and BAC sequencing:, Weining S, Cui L, Du X, Feng K, Nie X, Tong W, Wang L; Figures:, Borrill P, Gundlach H, Galvez S, Kaithakottil G, Lang D, Lux T, Mascher M, Ormanbekova D, Prade V, Ramirez-Gonzalez RH, Spannagl M, Stein N, Uauy C, Venturini L; Manuscript writing team:, Stein N, Appels R, Eversole K, Rogers J, Borrill P, Cattivelli L, Choulet F, Hernandez P, Kanyuka K, Lang D, Mascher M, Nilsen K, Paux E, Pozniak CJ, Ramirez-Gonzalez RH, Šimková H, Small I, Spannagl M, Swarbreck D, Uauy C.

Science. 2018 Aug 17;361(6403). pii: eaar7191. doi: 10.1126/science.aar7191. Epub 2018 Aug 16.

PMID:
30115783
6.

Medical students' attitudes towards increasing early clinical exposure to primary care.

van Oppen J, Camm C, Sahota G, Taggar J, Knox R.

Educ Prim Care. 2018 Sep;29(5):312-313. doi: 10.1080/14739879.2018.1495107. Epub 2018 Jul 26. No abstract available.

PMID:
30048207
7.

Mapping Conformational Dynamics to Individual Steps in the TEM-1 β-Lactamase Catalytic Mechanism.

Knox R, Lento C, Wilson DJ.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3311-3322. doi: 10.1016/j.jmb.2018.06.045. Epub 2018 Jun 28.

PMID:
29964048
8.

Variation in hydroclimate sustains tropical forest biomass and promotes functional diversity.

Powell TL, Koven CD, Johnson DJ, Faybishenko B, Fisher RA, Knox RG, McDowell NG, Condit R, Hubbell SP, Wright SJ, Chambers JQ, Kueppers LM.

New Phytol. 2018 Aug;219(3):932-946. doi: 10.1111/nph.15271. Epub 2018 Jun 20.

PMID:
29923303
9.

Ecosystem heterogeneity and diversity mitigate Amazon forest resilience to frequent extreme droughts.

Longo M, Knox RG, Levine NM, Alves LF, Bonal D, Camargo PB, Fitzjarrald DR, Hayek MN, Restrepo-Coupe N, Saleska SR, da Silva R, Stark SC, Tapajós RP, Wiedemann KT, Zhang K, Wofsy SC, Moorcroft PR.

New Phytol. 2018 Aug;219(3):914-931. doi: 10.1111/nph.15185. Epub 2018 May 22.

PMID:
29786858
10.

Differential gene expression of Eph-ephrin A1 and LEPR-LEP with high or low number of embryos in pigs during implantation.

Fu Y, Knox RV, Li L, Ren S.

Reprod Domest Anim. 2018 Aug;53(4):937-946. doi: 10.1111/rda.13192. Epub 2018 May 8.

PMID:
29740882
11.

Abundance of the arbuscular mycorrhizal fungal taxa associated with the roots and rhizosphere soil of different durum wheat cultivars in the Canadian prairies.

Ellouze W, Hamel C, Singh AK, Mishra V, DePauw RM, Knox RE.

Can J Microbiol. 2018 Aug;64(8):527-536. doi: 10.1139/cjm-2017-0637. Epub 2018 Apr 10.

PMID:
29633625
12.

High-density genetic mapping of a major QTL for resistance to multiple races of loose smut in a tetraploid wheat cross.

Kumar S, Knox RE, Singh AK, DePauw RM, Campbell HL, Isidro-Sanchez J, Clarke FR, Pozniak CJ, N'Daye A, Meyer B, Sharpe A, Ruan Y, Cuthbert RD, Somers D, Fedak G.

PLoS One. 2018 Feb 27;13(2):e0192261. doi: 10.1371/journal.pone.0192261. eCollection 2018.

13.

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.

Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.

J Clin Invest. 2018 Apr 2;128(4):1496-1508. doi: 10.1172/JCI98589. Epub 2018 Mar 12.

14.

Discovery of morpholine-based aryl sulfonamides as Nav1.7 inhibitors.

Wu YJ, Guernon J, McClure A, Venables B, Rajamani R, Robbins KJ, Knox RJ, Matchett M, Pieschl RL, Herrington J, Bristow LJ, Meanwell NA, Olson R, Thompson LA, Dzierba C.

Bioorg Med Chem Lett. 2018 Mar 1;28(5):958-962. doi: 10.1016/j.bmcl.2018.01.035. Epub 2018 Feb 1.

PMID:
29439904
15.

An improved cell-permeable fluorogenic substrate as the basis for a highly sensitive test for NAD(P)H quinone oxidoreductase 1 (NQO1) in living cells.

Cuff S, Lewis RD, Chinje E, Jaffar M, Knox R, Weeks I.

Free Radic Biol Med. 2018 Feb 20;116:141-148. doi: 10.1016/j.freeradbiomed.2018.01.009. Epub 2018 Jan 8.

PMID:
29325897
16.

Correction: Single Marker and Haplotype-Based Association Analysis of Semolina and Pasta Colour in Elite Durum Wheat Breeding Lines Using a High-Density Consensus Map.

N'Diaye A, Haile JK, Cory AT, Clarke FR, Clarke JM, Knox RE, Pozniak CJ.

PLoS One. 2017 Oct 24;12(10):e0187178. doi: 10.1371/journal.pone.0187178. eCollection 2017.

17.

Hypoxia-ischemia modifies postsynaptic GluN2B-containing NMDA receptor complexes in the neonatal mouse brain.

Lu F, Shao G, Wang Y, Guan S, Burlingame AL, Liu X, Liang X, Knox R, Ferriero DM, Jiang X.

Exp Neurol. 2018 Jan;299(Pt A):65-74. doi: 10.1016/j.expneurol.2017.10.005. Epub 2017 Oct 6.

PMID:
28993251
18.

Vegetation demographics in Earth System Models: A review of progress and priorities.

Fisher RA, Koven CD, Anderegg WRL, Christoffersen BO, Dietze MC, Farrior CE, Holm JA, Hurtt GC, Knox RG, Lawrence PJ, Lichstein JW, Longo M, Matheny AM, Medvigy D, Muller-Landau HC, Powell TL, Serbin SP, Sato H, Shuman JK, Smith B, Trugman AT, Viskari T, Verbeeck H, Weng E, Xu C, Xu X, Zhang T, Moorcroft PR.

Glob Chang Biol. 2018 Jan;24(1):35-54. doi: 10.1111/gcb.13910. Epub 2017 Oct 24. Review.

PMID:
28921829
19.

Ovulation and fertility responses for sows receiving once daily boar exposure after weaning and OvuGel® followed by a single fixed time post cervical artificial insemination.

Ulguim RR, Bortolozzo FP, Wentz I, Johnston M, Webel SK, Arend L, Knox RV.

Theriogenology. 2018 Jan 1;105:27-33. doi: 10.1016/j.theriogenology.2017.09.005. Epub 2017 Sep 8.

20.

Quantitative trait loci for resistance to stripe rust of wheat revealed using global field nurseries and opportunities for stacking resistance genes.

Bokore FE, Cuthbert RD, Knox RE, Randhawa HS, Hiebert CW, DePauw RM, Singh AK, Singh A, Sharpe AG, N'Diaye A, Pozniak CJ, McCartney C, Ruan Y, Berraies S, Meyer B, Munro C, Hay A, Ammar K, Huerta-Espino J, Bhavani S.

Theor Appl Genet. 2017 Dec;130(12):2617-2635. doi: 10.1007/s00122-017-2980-7. Epub 2017 Sep 14.

PMID:
28913655
21.

Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure.

Felce JH, Latty SL, Knox RG, Mattick SR, Lui Y, Lee SF, Klenerman D, Davis SJ.

Cell Rep. 2017 Sep 12;20(11):2654-2665. doi: 10.1016/j.celrep.2017.08.072.

22.

Design and biological effects of a vaginally administered gel containing the GnRH agonist, triptorelin, for synchronizing ovulation in swine.

Knox RV, Stewart KR, Flowers WL, Swanson ME, Webel SK, Kraeling RR.

Theriogenology. 2018 May;112:44-52. doi: 10.1016/j.theriogenology.2017.08.021. Epub 2017 Aug 24.

PMID:
28863964
23.

Effects of estrus synchronization using Matrix® followed by treatment with the GnRH agonist triptorelin to control ovulation in mature gilts.

Knox RV, Webel SK, Swanson M, Johnston ME, Kraeling RR.

Anim Reprod Sci. 2017 Oct;185:66-74. doi: 10.1016/j.anireprosci.2017.08.003. Epub 2017 Aug 14.

PMID:
28823417
24.

Discovery of non-zwitterionic aryl sulfonamides as Nav1.7 inhibitors with efficacy in preclinical behavioral models and translational measures of nociceptive neuron activation.

Wu YJ, Guernon J, McClure A, Luo G, Rajamani R, Ng A, Easton A, Newton A, Bourin C, Parker D, Mosure K, Barnaby O, Soars MG, Knox RJ, Matchett M, Pieschl R, Herrington J, Chen P, Sivarao DV, Bristow LJ, Meanwell NA, Bronson J, Olson R, Thompson LA, Dzierba C.

Bioorg Med Chem. 2017 Oct 15;25(20):5490-5505. doi: 10.1016/j.bmc.2017.08.012. Epub 2017 Aug 9.

PMID:
28818462
25.

Area Health Education Center (AHEC) programs for rural and underrepresented minority students in the Alabama Black Belt.

Patel A, Knox RJ, Logan A, Summerville K.

Arch Public Health. 2017 Jul 24;75:32. doi: 10.1186/s13690-017-0200-1. eCollection 2017.

26.

Atypical neurofibromatosis type 1 with unilateral limb hypertrophy mimicking overgrowth syndrome.

Tripolszki K, Farkas K, Sulák A, Szolnoky G, Duga B, Melegh B, Knox RG, Parker VER, Semple RK, Kemény L, Széll M, Nagy N.

Clin Exp Dermatol. 2017 Oct;42(7):763-766. doi: 10.1111/ced.13154. Epub 2017 Jun 8.

PMID:
28598037
27.

Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase.

Leiter SM, Parker VER, Welters A, Knox R, Rocha N, Clark G, Payne F, Lotta L, Harris J, Guerrero-Fernández J, González-Casado I, García-Miñaur S, Gordo G, Wareham N, Martínez-Glez V, Allison M, O'Rahilly S, Barroso I, Meissner T, Davies S, Hussain K, Temple K, Barreda-Bonis AC, Kummer S, Semple RK.

Eur J Endocrinol. 2017 Aug;177(2):175-186. doi: 10.1530/EJE-17-0132. Epub 2017 May 31.

28.

Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics.

Lento C, Zhu S, Brown KA, Knox R, Liuni P, Wilson DJ.

J Vis Exp. 2017 Apr 17;(122). doi: 10.3791/55464.

PMID:
28448048
29.

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.

Rocha N, Bulger DA, Frontini A, Titheradge H, Gribsholt SB, Knox R, Page M, Harris J, Payne F, Adams C, Sleigh A, Crawford J, Gjesing AP, Bork-Jensen J, Pedersen O, Barroso I, Hansen T, Cox H, Reilly M, Rossor A, Brown RJ, Taylor SI, McHale D, Armstrong M, Oral EA, Saudek V, O'Rahilly S, Maher ER, Richelsen B, Savage DB, Semple RK.

Elife. 2017 Apr 19;6. pii: e23813. doi: 10.7554/eLife.23813.

30.

High density mapping and haplotype analysis of the major stem-solidness locus SSt1 in durum and common wheat.

Nilsen KT, N'Diaye A, MacLachlan PR, Clarke JM, Ruan Y, Cuthbert RD, Knox RE, Wiebe K, Cory AT, Walkowiak S, Beres BL, Graf RJ, Clarke FR, Sharpe AG, Distelfeld A, Pozniak CJ.

PLoS One. 2017 Apr 11;12(4):e0175285. doi: 10.1371/journal.pone.0175285. eCollection 2017.

31.

BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.

King D, Iwuagwu C, Cook J, McDonald IM, Mate R, Zusi FC, Hill MD, Fang H, Zhao R, Wang B, Easton AE, Miller R, Post-Munson D, Knox RJ, Gallagher L, Westphal R, Molski T, Fan J, Clarke W, Benitex Y, Lentz KA, Denton R, Morgan D, Zaczek R, Lodge NJ, Bristow LJ, Macor JE, Olson RE.

ACS Med Chem Lett. 2017 Feb 8;8(3):366-371. doi: 10.1021/acsmedchemlett.7b00032. eCollection 2017 Mar 9.

32.

Proteomic Analysis of Mouse Cortex Postsynaptic Density following Neonatal Brain Hypoxia-Ischemia.

Shao G, Wang Y, Guan S, Burlingame AL, Lu F, Knox R, Ferriero DM, Jiang X.

Dev Neurosci. 2017;39(1-4):66-81. doi: 10.1159/000456030. Epub 2017 Mar 18.

33.

Effect of numbers of sperm and timing of a single, post-cervical insemination on the fertility of weaned sows treated with OvuGel®.

Knox RV, Esparza-Harris KC, Johnston ME, Webel SK.

Theriogenology. 2017 Apr 1;92:197-203. doi: 10.1016/j.theriogenology.2017.01.033. Epub 2017 Jan 20.

PMID:
28237336
34.

Development of New Benzenesulfonamides As Potent and Selective Nav1.7 Inhibitors for the Treatment of Pain.

Wu YJ, Guernon J, Shi J, Ditta J, Robbins KJ, Rajamani R, Easton A, Newton A, Bourin C, Mosure K, Soars MG, Knox RJ, Matchett M, Pieschl RL, Post-Munson DJ, Wang S, Herrington J, Graef J, Newberry K, Bristow LJ, Meanwell NA, Olson R, Thompson LA, Dzierba C.

J Med Chem. 2017 Mar 23;60(6):2513-2525. doi: 10.1021/acs.jmedchem.6b01918. Epub 2017 Mar 10.

PMID:
28234467
35.

Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR.

Iwuagwu C, King D, McDonald IM, Cook J, Zusi FC, Hill MD, Mate RA, Fang H, Knox R, Gallagher L, Post-Munson Amy Easton D, Miller R, Benitex Y, Siuciak J, Lodge N, Zaczek R, Morgan D, Bristow L, Macor JE, Olson RE.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1261-1266. doi: 10.1016/j.bmcl.2017.01.058. Epub 2017 Jan 20.

PMID:
28169167
36.

Single Marker and Haplotype-Based Association Analysis of Semolina and Pasta Colour in Elite Durum Wheat Breeding Lines Using a High-Density Consensus Map.

N'Diaye A, Haile JK, Cory AT, Clarke FR, Clarke JM, Knox RE, Pozniak CJ.

PLoS One. 2017 Jan 30;12(1):e0170941. doi: 10.1371/journal.pone.0170941. eCollection 2017. Erratum in: PLoS One. 2017 Oct 24;12 (10 ):e0187178.

37.

B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Post-Munson DJ, Pieschl RL, Molski TF, Graef JD, Hendricson AW, Knox RJ, McDonald IM, Olson RE, Macor JE, Weed MR, Bristow LJ, Kiss L, Ahlijanian MK, Herrington J.

Eur J Pharmacol. 2017 Mar 15;799:16-25. doi: 10.1016/j.ejphar.2017.01.037. Epub 2017 Jan 26.

PMID:
28132910
38.

Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.

Hill MD, Fang H, King HD, Iwuagwu CI, McDonald IM, Cook J, Zusi FC, Mate RA, Knox RJ, Post-Munson D, Easton A, Miller R, Lentz K, Clarke W, Benitex Y, Lodge N, Zaczek R, Denton R, Morgan D, Bristow L, Macor JE, Olson R.

ACS Med Chem Lett. 2016 Dec 1;8(1):133-137. doi: 10.1021/acsmedchemlett.6b00471. eCollection 2017 Jan 12.

39.

Effect of timing of relocation of replacement gilts from group pens to individual stalls before breeding on fertility and well-being.

Knox RV, Shen J, Greiner LL, Connor JF.

J Anim Sci. 2016 Dec;94(12):5114-5121. doi: 10.2527/jas.2016-0799.

PMID:
28046180
40.

meso-Acetoxymethyl BODIPY dyes for photodynamic therapy: improved photostability of singlet oxygen photosensitizers.

Lincoln R, Durantini AM, Greene LE, Martínez SR, Knox R, Becerra MC, Cosa G.

Photochem Photobiol Sci. 2017 Feb 15;16(2):178-184. doi: 10.1039/c6pp00166a.

PMID:
27966708
41.

Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship.

Cook J, Zusi FC, McDonald IM, King D, Hill MD, Iwuagwu C, Mate RA, Fang H, Zhao R, Wang B, Cutrone J, Ma B, Gao Q, Knox RJ, Matchett M, Gallagher L, Ferrante M, Post-Munson D, Molski T, Easton A, Miller R, Jones K, Digavalli S, Healy F, Lentz K, Benitex Y, Clarke W, Natale J, Siuciak JA, Lodge N, Zaczek R, Denton R, Morgan D, Bristow LJ, Macor JE, Olson RE.

J Med Chem. 2016 Dec 22;59(24):11171-11181. doi: 10.1021/acs.jmedchem.6b01506. Epub 2016 Dec 13.

PMID:
27958732
42.

Studies relating to the synthesis, enzymatic reduction and cytotoxicity of a series of nitroaromatic prodrugs.

Burke PJ, Wong LC, Jenkins TC, Knox RJ, Meikle IT, Stanforth SP.

Bioorg Med Chem Lett. 2016 Dec 15;26(24):5851-5854. doi: 10.1016/j.bmcl.2016.11.024. Epub 2016 Nov 11.

PMID:
27876476
43.

Improving Primary Care Retention in Medically Underserved Areas: What's a Clinic to Do?

Scarbrough AW, Moore M, Shelton SR, Knox RJ.

Health Care Manag (Frederick). 2016 Oct/Dec;35(4):368-372.

PMID:
27676371
44.

GLOBAL CHANGE RESEARCH. The challenge of climate-change neoskepticism.

Stern PC, Perkins JH, Sparks RE, Knox RA.

Science. 2016 Aug 12;353(6300):653-4. doi: 10.1126/science.aaf6675. No abstract available.

PMID:
27516588
45.

Nephroblastomatosis or Wilms tumor in a fourth patient with a somatic PIK3CA mutation.

Gripp KW, Baker L, Kandula V, Conard K, Scavina M, Napoli JA, Griffin GC, Thacker M, Knox RG, Clark GR, Parker VE, Semple R, Mirzaa G, Keppler-Noreuil KM.

Am J Med Genet A. 2016 Oct;170(10):2559-69. doi: 10.1002/ajmg.a.37758. Epub 2016 May 18. Review.

46.

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.

Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B.

Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982.

47.

Somatic mosaicism of the PIK3CA gene identified in a Hungarian girl with macrodactyly and syndactyly.

Tripolszki K, Knox R, Parker V, Semple R, Farkas K, Sulák A, Horváth E, Széll M, Nagy N.

Eur J Med Genet. 2016 Apr;59(4):223-6. doi: 10.1016/j.ejmg.2016.02.002. Epub 2016 Feb 3.

PMID:
26851524
48.

Potential to breed for mycorrhizal association in durum wheat.

Ellouze W, Hamel C, DePauw RM, Knox RE, Cuthbert RD, Singh AK.

Can J Microbiol. 2016 Mar;62(3):263-71. doi: 10.1139/cjm-2014-0598. Epub 2015 Dec 18.

PMID:
26825726
49.

Surgical management of medically refractory epilepsy in patients with polymicrogyria.

Wang DD, Knox R, Rolston JD, Englot DJ, Barkovich AJ, Tihan T, Auguste KI, Knowlton RC, Cornes SB, Chang EF.

Epilepsia. 2016 Jan;57(1):151-61. doi: 10.1111/epi.13264. Epub 2015 Dec 9.

50.

Genetic mapping of common bunt resistance and plant height QTL in wheat.

Singh A, Knox RE, DePauw RM, Singh AK, Cuthbert RD, Kumar S, Campbell HL.

Theor Appl Genet. 2016 Feb;129(2):243-56. doi: 10.1007/s00122-015-2624-8. Epub 2015 Oct 31.

PMID:
26520114

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