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Items: 1 to 50 of 86

1.

Substance Use and HIV Risk Among Men Who Have Sex With Men in Africa: A Systematic Review.

Sandfort TGM, Knox JR, Alcala C, El-Bassel N, Kuo I, Smith LR.

J Acquir Immune Defic Syndr. 2017 Oct 1;76(2):e34-e46. doi: 10.1097/QAI.0000000000001462. Review.

2.

Intimate Partner Violence and Child Behavioral Problems in South Africa.

Chander P, Kvalsvig J, Mellins CA, Kauchali S, Arpadi SM, Taylor M, Knox JR, Davidson LL.

Pediatrics. 2017 Mar;139(3). pii: e20161059. doi: 10.1542/peds.2016-1059.

3.

Evolutionary Dynamics of Pandemic Methicillin-Sensitive Staphylococcus aureus ST398 and Its International Spread via Routes of Human Migration.

Uhlemann AC, McAdam PR, Sullivan SB, Knox JR, Khiabanian H, Rabadan R, Davies PR, Fitzgerald JR, Lowy FD.

MBio. 2017 Jan 17;8(1). pii: e01375-16. doi: 10.1128/mBio.01375-16.

4.

Same-Sex and Different-Sex Parent Households and Child Health Outcomes: Findings from the National Survey of Children's Health.

Bos HM, Knox JR, van Rijn-van Gelderen L, Gartrell NK.

J Dev Behav Pediatr. 2016 Apr;37(3):179-87. doi: 10.1097/DBP.0000000000000288.

5.

Molecular tracing of the emergence, diversification, and transmission of S. aureus sequence type 8 in a New York community.

Uhlemann AC, Dordel J, Knox JR, Raven KE, Parkhill J, Holden MT, Peacock SJ, Lowy FD.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6738-43. doi: 10.1073/pnas.1401006111. Epub 2014 Apr 21.

6.

Exploring the potential for a culturally relevant HIV intervention project: a Swaziland example.

Knox JR.

Anthropol Med. 2010 Apr;17(1):87-98. doi: 10.1080/13648471003607615.

PMID:
20419519
7.

Inhibition of class A beta-lactamases by carbapenems: crystallographic observation of two conformations of meropenem in SHV-1.

Nukaga M, Bethel CR, Thomson JM, Hujer AM, Distler A, Anderson VE, Knox JR, Bonomo RA.

J Am Chem Soc. 2008 Sep 24;130(38):12656-62. doi: 10.1021/ja7111146. Epub 2008 Aug 30.

8.

Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.

Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Yamamura I, Ado M, Tsuyoshi T, Dos Santos O, Gu Y, Sum FW, Li Z, Francisco G, Lin YI, Petersen PJ, Yang Y, Kumagai T, Weiss WJ, Shlaes DM, Knox JR, Mansour TS.

J Med Chem. 2006 Jul 27;49(15):4623-37.

PMID:
16854068
9.

Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.

Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR.

J Med Chem. 2004 Dec 16;47(26):6556-68.

PMID:
15588091
10.
12.
13.

Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate.

Nukaga M, Abe T, Venkatesan AM, Mansour TS, Bonomo RA, Knox JR.

Biochemistry. 2003 Nov 18;42(45):13152-9.

PMID:
14609325
14.

Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme.

Nukaga M, Mayama K, Hujer AM, Bonomo RA, Knox JR.

J Mol Biol. 2003 Apr 18;328(1):289-301.

PMID:
12684014
15.
16.

Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.

McDonough MA, Anderson JW, Silvaggi NR, Pratt RF, Knox JR, Kelly JA.

J Mol Biol. 2002 Sep 6;322(1):111-22.

PMID:
12215418
17.

Mutational replacement of Leu-293 in the class C Enterobacter cloacae P99 beta-lactamase confers increased MIC of cefepime.

Vakulenko SB, Golemi D, Geryk B, Suvorov M, Knox JR, Mobashery S, Lerner SA.

Antimicrob Agents Chemother. 2002 Jun;46(6):1966-70.

18.

Structure of an extended-spectrum class A beta-lactamase from Proteus vulgaris K1.

Nukaga M, Mayama K, Crichlow GV, Knox JR.

J Mol Biol. 2002 Mar 15;317(1):109-17.

PMID:
11916382
19.

Crystallization and preliminary X-ray study of OXA-1, a class D beta-lactamase.

Sun T, Nukaga M, Mayama K, Crichlow GV, Kuzin AP, Knox JR.

Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1912-4. Epub 2001 Nov 21.

PMID:
11717515
20.

Inhibition of class C beta-lactamases: structure of a reaction intermediate with a cephem sulfone.

Crichlow GV, Nukaga M, Doppalapudi VR, Buynak JD, Knox JR.

Biochemistry. 2001 May 29;40(21):6233-9.

PMID:
11371184
21.

Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam.

Kuzin AP, Nukaga M, Nukaga Y, Hujer A, Bonomo RA, Knox JR.

Biochemistry. 2001 Feb 13;40(6):1861-6.

PMID:
11327849
22.

Enzymes of vancomycin resistance: the structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mesenteroides.

Kuzin AP, Sun T, Jorczak-Baillass J, Healy VL, Walsh CT, Knox JR.

Structure. 2000 May 15;8(5):463-70.

23.

Vancomycin resistance in enterococci: reprogramming of the D-ala-D-Ala ligases in bacterial peptidoglycan biosynthesis.

Healy VL, Lessard IA, Roper DI, Knox JR, Walsh CT.

Chem Biol. 2000 May;7(5):R109-19. Review.

24.

Structure of the extended-spectrum class C beta-lactamase of Enterobacter cloacae GC1, a natural mutant with a tandem tripeptide insertion.

Crichlow GV, Kuzin AP, Nukaga M, Mayama K, Sawai T, Knox JR.

Biochemistry. 1999 Aug 10;38(32):10256-61.

PMID:
10441119
25.

Structure of the SHV-1 beta-lactamase.

Kuzin AP, Nukaga M, Nukaga Y, Hujer AM, Bonomo RA, Knox JR.

Biochemistry. 1999 May 4;38(18):5720-7.

PMID:
10231522
26.

Structure-function studies of Ser-289 in the class C beta-lactamase from Enterobacter cloacae P99.

Trépanier S, Knox JR, Clairoux N, Sanschagrin F, Levesque RC, Huletsky A.

Antimicrob Agents Chemother. 1999 Mar;43(3):543-8.

27.

Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme.

Lin S, Thomas M, Shlaes DM, Rudin SD, Knox JR, Anderson V, Bonomo RA.

Biochem J. 1998 Jul 15;333 ( Pt 2):395-400.

28.

Characterization of a new TEM-derived beta-lactamase produced in a Serratia marcescens strain.

Perilli M, Felici A, Franceschini N, De Santis A, Pagani L, Luzzaro F, Oratore A, Rossolini GM, Knox JR, Amicosante G.

Antimicrob Agents Chemother. 1997 Nov;41(11):2374-82.

29.

Construction and characterization of an OHIO-1 beta-lactamase bearing Met69Ile and Gly238Ser mutations.

Bonomo RA, Knox JR, Rudin SD, Shlaes DM.

Antimicrob Agents Chemother. 1997 Sep;41(9):1940-3.

30.

D-alanine:D-alanine ligase: phosphonate and phosphinate intermediates with wild type and the Y216F mutant.

Fan C, Park IS, Walsh CT, Knox JR.

Biochemistry. 1997 Mar 4;36(9):2531-8.

PMID:
9054558
31.

Molecular evolution of bacterial beta-lactam resistance.

Knox JR, Moews PC, Frere JM.

Chem Biol. 1996 Nov;3(11):937-47.

32.

Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure.

Knox JR.

Antimicrob Agents Chemother. 1995 Dec;39(12):2593-601. Review. No abstract available.

34.

The enigmatic catalytic mechanism of active-site serine beta-lactamases.

Galleni M, Lamotte-Brasseur J, Raquet X, Dubus A, Monnaie D, Knox JR, Frère JM.

Biochem Pharmacol. 1995 May 11;49(9):1171-8. Review. No abstract available.

PMID:
7763298
35.

beta-Lactamase mutations far from the active site influence inhibitor binding.

Bonomo RA, Dawes CG, Knox JR, Shlaes DM.

Biochim Biophys Acta. 1995 Feb 22;1247(1):121-5.

PMID:
7873581
36.

Complementary roles of mutations at positions 69 and 242 in a class A beta-lactamase.

Bonomo RA, Dawes CG, Knox JR, Shlaes DM.

Biochim Biophys Acta. 1995 Feb 22;1247(1):113-20.

PMID:
7873579
37.
38.

Vancomycin resistance: structure of D-alanine:D-alanine ligase at 2.3 A resolution.

Fan C, Moews PC, Walsh CT, Knox JR.

Science. 1994 Oct 21;266(5184):439-43.

PMID:
7939684
39.
40.

A structure-based analysis of the inhibition of class A beta-lactamases by sulbactam.

Imtiaz U, Billings EM, Knox JR, Mobashery S.

Biochemistry. 1994 May 17;33(19):5728-38.

PMID:
8180199
44.
45.
46.
48.

Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution.

Moews PC, Knox JR, Dideberg O, Charlier P, Frère JM.

Proteins. 1990;7(2):156-71.

49.

Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme.

Kelly JA, Knox JR, Zhao H, Frère JM, Ghaysen JM.

J Mol Biol. 1989 Sep 20;209(2):281-95.

50.

Studying enzyme-beta-lactam interactions using X-ray diffraction.

Kelly JA, Knox JR, Zhao H.

J Mol Graph. 1989 Jun;7(2):87-92.

PMID:
2488268

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