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Adjuvant Therapy for Biliary Tract Cancers.

Horgan AM, Knox JJ.

J Oncol Pract. 2018 Dec;14(12):701-708. doi: 10.1200/JOP.18.00558.


Host-specific signatures of the cell wall changes induced by the plant parasitic nematode, Meloidogyne incognita.

Bozbuga R, Lilley CJ, Knox JP, Urwin PE.

Sci Rep. 2018 Nov 23;8(1):17302. doi: 10.1038/s41598-018-35529-7.


Characterisation of CRISPR mutants targeting genes modulating pectin degradation in ripening tomato.

Wang D, Samsulrizal N, Yan C, Allcock NS, Craigon J, Blanco-Ulate B, Ortega-Salazar I, Marcus SE, Bagheri HM, Perez-Fons L, Fraser PD, Foster T, Fray RG, Knox JP, Seymour GB.

Plant Physiol. 2018 Nov 20. pii: pp.01187.2018. doi: 10.1104/pp.18.01187. [Epub ahead of print]


Sorafenib as first-line therapy in patients with advanced Child-Pugh B hepatocellular carcinoma-a meta-analysis.

McNamara MG, Slagter AE, Nuttall C, Frizziero M, Pihlak R, Lamarca A, Tariq N, Valle JW, Hubner RA, Knox JJ, Amir E.

Eur J Cancer. 2018 Dec;105:1-9. doi: 10.1016/j.ejca.2018.09.031. Epub 2018 Oct 29.


Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study.

Amin A, Plimack ER, Ernstoff MS, Lewis LD, Bauer TM, McDermott DF, Carducci M, Kollmannsberger C, Rini BI, Heng DYC, Knox J, Voss MH, Spratlin J, Berghorn E, Yang L, Hammers HJ.

J Immunother Cancer. 2018 Oct 22;6(1):109. doi: 10.1186/s40425-018-0420-0.


Active Smoking Is Associated With Worse Prognosis in Metastatic Renal Cell Carcinoma Patients Treated With Targeted Therapies.

Kroeger N, Li H, De Velasco G, Donskov F, Sim HW, Stühler V, Wells JC, Stukalin I, Heide J, Bedke J, Agarwal N, Parekh H, Rini BI, Knox JJ, Pantuck A, Choueiri TK, Chin Heng DY.

Clin Genitourin Cancer. 2018 Sep 12. pii: S1558-7673(18)30506-8. doi: 10.1016/j.clgc.2018.09.006. [Epub ahead of print]


Assessing the bioactivity of crystalline silica in heated high-temperature insulation wools.

Boyles MSP, Brown D, Knox J, Horobin M, Miller MR, Johnston HJ, Stone V.

Inhal Toxicol. 2018 Oct 17:1-18. doi: 10.1080/08958378.2018.1513610. [Epub ahead of print]


Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease.

Whitesell JD, Buckley AR, Knox JE, Kuan L, Graddis N, Pelos A, Mukora A, Wakeman W, Bohn P, Ho A, Hirokawa KE, Harris JA.

J Comp Neurol. 2018 Oct 12. doi: 10.1002/cne.24555. [Epub ahead of print]


β-(1,4)-Galactan remodelling in Arabidopsis cell walls affects the xyloglucan structure during elongation.

Moneo-Sánchez M, Alonso-Chico A, Knox JP, Dopico B, Labrador E, Martín I.

Planta. 2018 Sep 11. doi: 10.1007/s00425-018-3008-5. [Epub ahead of print]


Reduction in Nonabstinent WHO Drinking Risk Levels and Change in Risk for Liver Disease and Positive AUDIT-C Scores: Prospective 3-Year Follow-Up Results in the U.S. General Population.

Knox J, Wall M, Witkiewitz K, Kranzler HR, Falk D, Litten R, Mann K, O'Malley SS, Scodes J, Anton R, Hasin DS; Alcohol Clinical Trials (ACTIVE) Workgroup.

Alcohol Clin Exp Res. 2018 Nov;42(11):2256-2265. doi: 10.1111/acer.13884. Epub 2018 Oct 3.


Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.

Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, Radetzki S, Vogt I, Hähn K, De Luca C, Cardoso C, Hamad S, Igual Gil C, Roy P, Albiges-Rizo C, Faurobert E, von Kries JP, Campillos M, Tournier-Lasserve E, Derry WB, Abdelilah-Seyfried S.

EMBO Mol Med. 2018 Oct;10(10). pii: e9155. doi: 10.15252/emmm.201809155.


Tumor Platinum Concentrations and Pathological Responses Following Cisplatin-Containing Chemotherapy in Gastric Cancer Patients.

Cao Y, Chang Q, Cabanero M, Zhang W, Hafezi-Bakhtiari S, Hedley D, Darling G, Quereshy F, Jang R, Elimova E, Knox J, Ornatsky O, Serra S, Chen E.

J Gastrointest Cancer. 2018 Aug 16. doi: 10.1007/s12029-018-0153-9. [Epub ahead of print]


Health-related quality of life measure distinguishes between low and high clinical T stages in esophageal cancer.

Kidane B, Ali A, Sulman J, Wong R, Knox JJ, Darling GE.

Ann Transl Med. 2018 Jul;6(13):270. doi: 10.21037/atm.2018.06.03.


The periodical cicada four-year acceleration hypothesis revisited and the polyphyletic nature of Brood V, including an updated crowd-source enhanced map (Hemiptera: Cicadidae: Magicicada).

Cooley JR, Arguedas N, Bonaros E, Bunker G, Chiswell SM, DeGiovine A, Edwards M, Hassanieh D, Haji D, Knox J, Kritsky G, Mills C, Mozgai D, Troutman R, Zyla J, Hasegawa H, Sota T, Yoshimura J, Simon C.

PeerJ. 2018 Jul 31;6:e5282. doi: 10.7717/peerj.5282. eCollection 2018.


Screening for Mental Health Among Young South African Children: The Use of the Strengths and Difficulties Questionnaire (SDQ).

Mellins CA, Xu Q, Nestadt DF, Knox J, Kauchali S, Arpadi S, Kvalsvig J, Shrout PE, Davidson LL.

Glob Soc Welf. 2018 Mar;5(1):29-38. Epub 2018 Jan 29.


Baseline Albumin-Bilirubin (ALBI) Score in Western Patients With Hepatocellular Carcinoma Treated With Stereotactic Body Radiation Therapy (SBRT).

Murray LJ, Sykes J, Brierley J, Kim JJ, Wong RKS, Ringash J, Craig T, Velec M, Lindsay P, Knox JJ, Dawson LA.

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):900-909. doi: 10.1016/j.ijrobp.2018.04.011. Epub 2018 Apr 12.


Screening for developmental disabilities in HIV positive and HIV negative children in South Africa: Results from the Asenze Study.

Knox J, Arpadi SM, Kauchali S, Craib M, Kvalsvig JD, Taylor M, Bah F, Mellins C, Davidson LL.

PLoS One. 2018 Jul 3;13(7):e0199860. doi: 10.1371/journal.pone.0199860. eCollection 2018.


Elicitors and defense gene induction in plants with altered lignin compositions.

Gallego-Giraldo L, Posé S, Pattathil S, Peralta AG, Hahn MG, Ayre BG, Sunuwar J, Hernandez J, Patel M, Shah J, Rao X, Knox JP, Dixon RA.

New Phytol. 2018 Sep;219(4):1235-1251. doi: 10.1111/nph.15258. Epub 2018 Jun 27.


Health utility scores from EQ-5D and health-related quality of life in patients with esophageal cancer: a real-world cross-sectional study.

Doherty MK, Leung Y, Su J, Naik H, Patel D, Eng L, Kong QQ, Mohsin F, Brown MC, Espin-Garcia O, Vennettilli A, Renouf DJ, Faluyi OO, Knox JJ, MacKay H, Wong R, Howell D, Mittmann N, Darling GE, Cella D, Xu W, Liu G.

Dis Esophagus. 2018 Dec 1;31(12). doi: 10.1093/dote/doy058.


Extraction, texture analysis and polysaccharide epitope mapping data of sequential extracts of strawberry, apple, tomato and aubergine fruit parenchyma.

Cornuault V, Pose S, Knox JP.

Data Brief. 2018 Jan 31;17:314-320. doi: 10.1016/j.dib.2018.01.013. eCollection 2018 Apr.


Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial.

Zhu AX, Finn RS, Edeline J, Cattan S, Ogasawara S, Palmer D, Verslype C, Zagonel V, Fartoux L, Vogel A, Sarker D, Verset G, Chan SL, Knox J, Daniele B, Webber AL, Ebbinghaus SW, Ma J, Siegel AB, Cheng AL, Kudo M; KEYNOTE-224 investigators.

Lancet Oncol. 2018 Jul;19(7):940-952. doi: 10.1016/S1470-2045(18)30351-6. Epub 2018 Jun 3. Erratum in: Lancet Oncol. 2018 Sep;19(9):e440.


Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.

Tiriac H, Belleau P, Engle DD, Plenker D, Deschênes A, Somerville TDD, Froeling FEM, Burkhart RA, Denroche RE, Jang GH, Miyabayashi K, Young CM, Patel H, Ma M, LaComb JF, Palmaira RLD, Javed AA, Huynh JC, Johnson M, Arora K, Robine N, Shah M, Sanghvi R, Goetz AB, Lowder CY, Martello L, Driehuis E, LeComte N, Askan G, Iacobuzio-Donahue CA, Clevers H, Wood LD, Hruban RH, Thompson E, Aguirre AJ, Wolpin BM, Sasson A, Kim J, Wu M, Bucobo JC, Allen P, Sejpal DV, Nealon W, Sullivan JD, Winter JM, Gimotty PA, Grem JL, DiMaio DJ, Buscaglia JM, Grandgenett PM, Brody JR, Hollingsworth MA, O'Kane GM, Notta F, Kim E, Crawford JM, Devoe C, Ocean A, Wolfgang CL, Yu KH, Li E, Vakoc CR, Hubert B, Fischer SE, Wilson JM, Moffitt R, Knox J, Krasnitz A, Gallinger S, Tuveson DA.

Cancer Discov. 2018 Sep;8(9):1112-1129. doi: 10.1158/2159-8290.CD-18-0349. Epub 2018 May 31.


Prognosis of patients with hepatocellular carcinoma treated with sorafenib: a comparison of five models in a large Canadian database.

Samawi HH, Sim HW, Chan KK, Alghamdi MA, Lee-Ying RM, Knox JJ, Gill P, Romagnino A, Batuyong E, Ko YJ, Davies JM, Lim HJ, Cheung WY, Tam VC; CHORD Consortium.

Cancer Med. 2018 May 15. doi: 10.1002/cam4.1493. [Epub ahead of print]


The ongoing challenge of large anal cancers: prospective long term outcomes of intensity-modulated radiation therapy with concurrent chemotherapy.

Hosni A, Han K, Le LW, Ringash J, Brierley J, Wong R, Dinniwell R, Brade A, Dawson LA, Cummings BJ, Krzyzanowska MK, Chen EX, Hedley D, Knox J, Easson AM, Lindsay P, Craig T, Kim J.

Oncotarget. 2018 Apr 17;9(29):20439-20450. doi: 10.18632/oncotarget.24926. eCollection 2018 Apr 17.


UTSA-16 Growth within 3D-Printed Co-Kaolin Monoliths with High Selectivity for CO2/CH4, CO2/N2, and CO2/H2 Separation.

Lawson S, Al-Naddaf Q, Krishnamurthy A, Amour MS, Griffin C, Rownaghi AA, Knox JC, Rezaei F.

ACS Appl Mater Interfaces. 2018 Jun 6;10(22):19076-19086. doi: 10.1021/acsami.8b05192. Epub 2018 May 24.


Developing a novel approach to existential suffering in cancer survivorship through Socratic dialogue.

Knox JBL.

Psychooncology. 2018 Jul;27(7):1865-1867. doi: 10.1002/pon.4750. Epub 2018 May 15. No abstract available.


Differential metabolism of pectic galactan in tomato and strawberry fruit: detection of the LM26 branched galactan epitope in ripe strawberry fruit.

Posé S, Marcus SE, Knox JP.

Physiol Plant. 2018 Sep;164(1):95-105. doi: 10.1111/ppl.12748. Epub 2018 Jul 11.


Lumbar Disc Herniation in Military Helicopter Pilots vs. Matched Controls.

Knox JB, Deal JB Jr, Knox JA.

Aerosp Med Hum Perform. 2018 May 1;89(5):442-445. doi: 10.3357/AMHP.4935.2018.


Tivantinib for second-line treatment of MET-high, advanced hepatocellular carcinoma (METIV-HCC): a final analysis of a phase 3, randomised, placebo-controlled study.

Rimassa L, Assenat E, Peck-Radosavljevic M, Pracht M, Zagonel V, Mathurin P, Rota Caremoli E, Porta C, Daniele B, Bolondi L, Mazzaferro V, Harris W, Damjanov N, Pastorelli D, Reig M, Knox J, Negri F, Trojan J, López López C, Personeni N, Decaens T, Dupuy M, Sieghart W, Abbadessa G, Schwartz B, Lamar M, Goldberg T, Shuster D, Santoro A, Bruix J.

Lancet Oncol. 2018 May;19(5):682-693. doi: 10.1016/S1470-2045(18)30146-3. Epub 2018 Apr 3.


Perspectives of primary health care staff on the implementation of a sexual health quality improvement program: a qualitative study in remote aboriginal communities in Australia.

Hengel B, Bell S, Garton L, Ward J, Rumbold A, Taylor-Thomson D, Silver B, McGregor S, Dyda A, Knox J, Guy R, Maher L, Kaldor JM; STRIVE Investigators.

BMC Health Serv Res. 2018 Apr 2;18(1):230. doi: 10.1186/s12913-018-3024-y.


What Do Residents Want for Burnout Prevention? … Time.

Fortenberry K, Knox J, Hala SV.

Acad Med. 2018 Mar;93(3):343-344. doi: 10.1097/ACM.0000000000002086. No abstract available.


Neoadjuvant hyperfractionated chemoradiation and liver transplantation for unresectable perihilar cholangiocarcinoma in Canada.

Loveday BPT, Knox JJ, Dawson LA, Metser U, Brade A, Horgan AM, Gallinger S, Greig PD, Moulton CA.

J Surg Oncol. 2018 Feb;117(2):213-219. doi: 10.1002/jso.24833.


Comparison of Practice Guidelines, BRCAPRO, and Genetic Counselor Estimates to Identify Germline BRCA1 and BRCA2 Mutations in Pancreatic Cancer.

Grant RC, Holter S, Borgida A, Dhani NC, Hedley DW, Knox JJ, Akbari MR, Zogopoulos G, Gallinger S.

J Genet Couns. 2018 Aug;27(4):988-995. doi: 10.1007/s10897-018-0212-1. Epub 2018 Feb 13.


Longitudinal changes in MR T1ρ/T2 signal of meniscus and its association with cartilage T1p/T2 in ACL-injured patients.

Knox J, Pedoia V, Wang A, Tanaka M, Joseph GB, Neumann J, Link TM, Li X, Ma CB.

Osteoarthritis Cartilage. 2018 May;26(5):689-696. doi: 10.1016/j.joca.2018.02.001. Epub 2018 Feb 10.


Final overall survival analysis for the phase II RECORD-3 study of first-line everolimus followed by sunitinib versus first-line sunitinib followed by everolimus in metastatic RCC.

Knox JJ, Barrios CH, Kim TM, Cosgriff T, Srimuninnimit V, Pittman K, Sabbatini R, Rha SY, Flaig TW, Page RD, Beck JT, Cheung F, Yadav S, Patel P, Geoffrois L, Niolat J, Berkowitz N, Marker M, Chen D, Motzer RJ.

Ann Oncol. 2018 Nov 1;29(11):2269. doi: 10.1093/annonc/mdx807. No abstract available.


What are the main inefficiencies in trial conduct: a survey of UKCRC registered clinical trials units in the UK.

Duley L, Gillman A, Duggan M, Belson S, Knox J, McDonald A, Rawcliffe C, Simon J, Sprosen T, Watson J, Wood W.

Trials. 2018 Jan 8;19(1):15. doi: 10.1186/s13063-017-2378-5.


Comparative in situ analysis reveals the dynamic nature of sclerenchyma cell walls of the fern Asplenium rutifolium.

Leroux O, Eder M, Saxe F, Dunlop JWC, Popper ZA, Viane RLL, Knox JP.

Ann Bot. 2018 Feb 12;121(2):345-358. doi: 10.1093/aob/mcx167.


Disentangling pectic homogalacturonan and rhamnogalacturonan-I polysaccharides: Evidence for sub-populations in fruit parenchyma systems.

Cornuault V, Posé S, Knox JP.

Food Chem. 2018 Apr 25;246:275-285. doi: 10.1016/j.foodchem.2017.11.025. Epub 2017 Nov 9.


Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.

Aung KL, Fischer SE, Denroche RE, Jang GH, Dodd A, Creighton S, Southwood B, Liang SB, Chadwick D, Zhang A, O'Kane GM, Albaba H, Moura S, Grant RC, Miller JK, Mbabaali F, Pasternack D, Lungu IM, Bartlett JMS, Ghai S, Lemire M, Holter S, Connor AA, Moffitt RA, Yeh JJ, Timms L, Krzyzanowski PM, Dhani N, Hedley D, Notta F, Wilson JM, Moore MJ, Gallinger S, Knox JJ.

Clin Cancer Res. 2018 Mar 15;24(6):1344-1354. doi: 10.1158/1078-0432.CCR-17-2994. Epub 2017 Dec 29.


Locally advanced pancreatic cancer: An emerging entity.

O Kane GM, Knox JJ.

Curr Probl Cancer. 2018 Jan - Feb;42(1):12-25. doi: 10.1016/j.currproblcancer.2017.10.006. Epub 2017 Nov 16. Review.


Branched Pectic Galactan in Phloem-Sieve-Element Cell Walls: Implications for Cell Mechanics.

Torode TA, O'Neill R, Marcus SE, Cornuault V, Pose S, Lauder RP, Kračun SK, Rydahl MG, Andersen MCF, Willats WGT, Braybrook SA, Townsend BJ, Clausen MH, Knox JP.

Plant Physiol. 2018 Feb;176(2):1547-1558. doi: 10.1104/pp.17.01568. Epub 2017 Nov 17.


Hepatocellular carcinoma in the era of immunotherapy.

Sim HW, Knox J.

Curr Probl Cancer. 2018 Jan - Feb;42(1):40-48. doi: 10.1016/j.currproblcancer.2017.10.007. Epub 2017 Nov 15. Review.


Xyloglucan is released by plants and promotes soil particle aggregation.

Galloway AF, Pedersen MJ, Merry B, Marcus SE, Blacker J, Benning LG, Field KJ, Knox JP.

New Phytol. 2018 Feb;217(3):1128-1136. doi: 10.1111/nph.14897. Epub 2017 Nov 15.


Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.

Chiu JW, Krzyzanowska MK, Serra S, Knox JJ, Dhani NC, Mackay H, Hedley D, Moore M, Liu G, Burkes RL, Brezden-Masley C, Roehrl MH, Craddock KJ, Tsao MS, Zhang T, Yu C, Kamel-Reid S, Siu LL, Bedard PL, Chen EX.

Clin Colorectal Cancer. 2018 Mar;17(1):73-79. doi: 10.1016/j.clcc.2017.10.010. Epub 2017 Oct 23.


Proteomic Screen of Brain Glycoproteome Reveals Prion Specific Marker of Pathogenesis.

Lamoureux L, Simon SLR, Waitt B, Knox JD.

Proteomics. 2018 Jan;18(1). doi: 10.1002/pmic.201700296.


Efficient preparation of Arabidopsis pollen tubes for ultrastructural analysis using chemical and cryo-fixation.

Ndinyanka Fabrice T, Kaech A, Barmettler G, Eichenberger C, Knox JP, Grossniklaus U, Ringli C.

BMC Plant Biol. 2017 Oct 27;17(1):176. doi: 10.1186/s12870-017-1136-x.


Altered rPrP substrate structures and their influence on real-time quaking induced conversion reactions.

Cheng K, Sloan A, Waitt B, Vendramelli R, Godal D, Simon SLR, O'Neil J, Carpenter M, Jackson D, Eastlake J, Mallinson G, Knox JD.

Protein Expr Purif. 2018 Mar;143:20-27. doi: 10.1016/j.pep.2017.10.007. Epub 2017 Oct 12.


A Synthetic Glycan Microarray Enables Epitope Mapping of Plant Cell Wall Glycan-Directed Antibodies.

Ruprecht C, Bartetzko MP, Senf D, Dallabernadina P, Boos I, Andersen MCF, Kotake T, Knox JP, Hahn MG, Clausen MH, Pfrengle F.

Plant Physiol. 2017 Nov;175(3):1094-1104. doi: 10.1104/pp.17.00737. Epub 2017 Sep 18.


An Update on Randomized Clinical Trials in Hepatocellular Carcinoma.

Sim HW, Knox J, Dawson LA.

Surg Oncol Clin N Am. 2017 Oct;26(4):647-666. doi: 10.1016/j.soc.2017.05.006. Epub 2017 Aug 4. Review.


Substance Use and HIV Risk Among Men Who Have Sex With Men in Africa: A Systematic Review.

Sandfort TGM, Knox JR, Alcala C, El-Bassel N, Kuo I, Smith LR.

J Acquir Immune Defic Syndr. 2017 Oct 1;76(2):e34-e46. doi: 10.1097/QAI.0000000000001462. Review.

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