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Items: 1 to 50 of 224

1.

Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.

Pasini A, Brand OJ, Jenkins G, Knox AJ, Pang L.

Biochim Biophys Acta. 2018 May;1861(5):463-472. doi: 10.1016/j.bbagrm.2018.03.007. Epub 2018 Mar 17.

2.

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.

Clifford RL, Fishbane N, Patel J, MacIsaac JL, McEwen LM, Fisher AJ, Brandsma CA, Nair P, Kobor MS, Hackett TL, Knox AJ.

Clin Epigenetics. 2018 Mar 5;10:32. doi: 10.1186/s13148-018-0464-5. eCollection 2018.

3.

PINX1 and TERT Are Required for TNF-α-Induced Airway Smooth Muscle Chemokine Gene Expression.

Deacon K, Knox AJ.

J Immunol. 2018 Feb 15;200(4):1283-1294. doi: 10.4049/jimmunol.1700414. Epub 2018 Jan 5.

PMID:
29305433
4.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study; response to comments.

Barr HL, Halliday N, Barrett DA, Williams P, Forrester DL, Peckham D, Williams K, Smyth AR, Honeybourne D, Whitehouse JL, Nash EF, Dewar J, Clayton A, Knox AJ, Cámara M, Fogarty AW.

J Cyst Fibros. 2017 Nov;16(6):e21. doi: 10.1016/j.jcf.2017.09.008. Epub 2017 Oct 25. No abstract available.

PMID:
29079141
5.

Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.

Coward WR, Brand OJ, Pasini A, Jenkins G, Knox AJ, Pang L.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):449-460. doi: 10.1165/rcmb.2017-0286OC.

PMID:
29053336
6.

FANTOM5 CAGE profiles of human and mouse samples.

Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, Nagao-Sato S, Nakazato K, Ninomiya N, Nishiyori-Sueki H, Noma S, Saijyo E, Saka A, Sakai M, Simon C, Suzuki N, Tagami M, Watanabe S, Yoshida S, Arner P, Axton RA, Babina M, Baillie JK, Barnett TC, Beckhouse AG, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Carlisle AJ, Clevers HC, Davis CA, Detmar M, Dohi T, Edge ASB, Edinger M, Ehrlund A, Ekwall K, Endoh M, Enomoto H, Eslami A, Fagiolini M, Fairbairn L, Farach-Carson MC, Faulkner GJ, Ferrai C, Fisher ME, Forrester LM, Fujita R, Furusawa JI, Geijtenbeek TB, Gingeras T, Goldowitz D, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Hasegawa Y, Herlyn M, Heutink P, Hitchens KJ, Hume DA, Ikawa T, Ishizu Y, Kai C, Kawamoto H, Kawamura YI, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klein S, Klinken SP, Knox AJ, Kojima S, Koseki H, Koyasu S, Lee W, Lennartsson A, Mackay-Sim A, Mejhert N, Mizuno Y, Morikawa H, Morimoto M, Moro K, Morris KJ, Motohashi H, Mummery CL, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nozaki T, Ogishima S, Ohkura N, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Passier R, Patrikakis M, Pombo A, Pradhan-Bhatt S, Qin XY, Rehli M, Rizzu P, Roy S, Sajantila A, Sakaguchi S, Sato H, Satoh H, Savvi S, Saxena A, Schmidl C, Schneider C, Schulze-Tanzil GG, Schwegmann A, Sheng G, Shin JW, Sugiyama D, Sugiyama T, Summers KM, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tomoiu A, Toyoda H, van de Wetering M, van den Berg LM, Verardo R, Vijayan D, Wells CA, Winteringham LN, Wolvetang E, Yamaguchi Y, Yamamoto M, Yanagi-Mizuochi C, Yoneda M, Yonekura Y, Zhang PG, Zucchelli S, Abugessaisa I, Arner E, Harshbarger J, Kondo A, Lassmann T, Lizio M, Sahin S, Sengstag T, Severin J, Shimoji H, Suzuki M, Suzuki H, Kawai J, Kondo N, Itoh M, Daub CO, Kasukawa T, Kawaji H, Carninci P, Forrest ARR, Hayashizaki Y.

Sci Data. 2017 Aug 29;4:170112. doi: 10.1038/sdata.2017.112.

7.

Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity.

O'Boyle NM, Barrett I, Greene LM, Carr M, Fayne D, Twamley B, Knox AJS, Keely NO, Zisterer DM, Meegan MJ.

J Med Chem. 2018 Jan 25;61(2):514-534. doi: 10.1021/acs.jmedchem.6b01917. Epub 2017 May 1.

PMID:
28426931
8.

Role of Rho-Associated Coiled-Coil Forming Kinase Isoforms in Regulation of Stiffness-Induced Myofibroblast Differentiation in Lung Fibrosis.

Htwe SS, Cha BH, Yue K, Khademhosseini A, Knox AJ, Ghaemmaghami AM.

Am J Respir Cell Mol Biol. 2017 Jun;56(6):772-783. doi: 10.1165/rcmb.2016-0306OC.

PMID:
28225294
9.

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema.

John AE, Wilson MR, Habgood A, Porte J, Tatler AL, Stavrou A, Miele G, Jolly L, Knox AJ, Takata M, Offermanns S, Jenkins RG.

Sci Signal. 2016 Oct 25;9(451):ra104.

10.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study.

Barr HL, Halliday N, Barrett DA, Williams P, Forrester DL, Peckham D, Williams K, Smyth AR, Honeybourne D, L Whitehouse J, Nash EF, Dewar J, Clayton A, Knox AJ, Cámara M, Fogarty AW.

J Cyst Fibros. 2017 Mar;16(2):230-238. doi: 10.1016/j.jcf.2016.10.005. Epub 2016 Oct 20.

11.

Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial.

Anderson JR, Mortimer K, Pang L, Smith KM, Bailey H, Hodgson DB, Shaw DE, Knox AJ, Harrison TW.

PLoS One. 2016 Aug 25;11(8):e0160257. doi: 10.1371/journal.pone.0160257. eCollection 2016.

12.

Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells.

Carr M, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ.

J Enzyme Inhib Med Chem. 2016;31(sup3):117-130. Epub 2016 Aug 1.

PMID:
27476825
13.

Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells.

Poghosyan A, Patel JK, Clifford RL, Knox AJ.

Biochem Biophys Res Commun. 2016 Aug 5;476(4):431-437. doi: 10.1016/j.bbrc.2016.05.140. Epub 2016 May 27.

PMID:
27240956
14.

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression.

Tatler AL, Habgood A, Porte J, John AE, Stavrou A, Hodge E, Kerama-Likoko C, Violette SM, Weinreb PH, Knox AJ, Laurent G, Parfrey H, Wolters PJ, Wallace W, Alberti S, Nordheim A, Jenkins G.

J Biol Chem. 2016 Apr 29;291(18):9540-53. doi: 10.1074/jbc.M115.692368. Epub 2016 Feb 9.

15.

Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial.

Forrester DL, Knox AJ, Smyth AR, Barr HL, Simms R, Pacey SJ, Pavord ID, Honeybourne D, Dewar J, Clayton A, Fogarty AW.

Pediatr Pulmonol. 2016 Mar;51(3):253-7. doi: 10.1002/ppul.23370. Epub 2015 Dec 27.

PMID:
26709241
16.

Matrix metalloproteinases -8 and -9 in the Airways, Blood and Urine During Exacerbations of COPD.

Cane JL, Mallia-Millanes B, Forrester DL, Knox AJ, Bolton CE, Johnson SR.

COPD. 2016;13(1):26-34. doi: 10.3109/15412555.2015.1043522. Epub 2015 Sep 29.

PMID:
26418236
17.

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort.

Shaw DE, Sousa AR, Fowler SJ, Fleming LJ, Roberts G, Corfield J, Pandis I, Bansal AT, Bel EH, Auffray C, Compton CH, Bisgaard H, Bucchioni E, Caruso M, Chanez P, Dahlén B, Dahlen SE, Dyson K, Frey U, Geiser T, Gerhardsson de Verdier M, Gibeon D, Guo YK, Hashimoto S, Hedlin G, Jeyasingham E, Hekking PP, Higenbottam T, Horváth I, Knox AJ, Krug N, Erpenbeck VJ, Larsson LX, Lazarinis N, Matthews JG, Middelveld R, Montuschi P, Musial J, Myles D, Pahus L, Sandström T, Seibold W, Singer F, Strandberg K, Vestbo J, Vissing N, von Garnier C, Adcock IM, Wagers S, Rowe A, Howarth P, Wagener AH, Djukanovic R, Sterk PJ, Chung KF; U-BIOPRED Study Group.

Eur Respir J. 2015 Nov;46(5):1308-21. doi: 10.1183/13993003.00779-2015. Epub 2015 Sep 10. Erratum in: Eur Respir J. 2017 Jun 22;49(6):.

18.

The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison.

Prayle AP, Jain K, Touw DJ, Koch BC, Knox AJ, Watson A, Smyth AR.

J Cyst Fibros. 2016 Jul;15(4):510-7. doi: 10.1016/j.jcf.2015.07.012. Epub 2015 Aug 15.

19.

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall.

Bridge JC, Aylott JW, Brightling CE, Ghaemmaghami AM, Knox AJ, Lewis MP, Rose FR, Morris GE.

J Vis Exp. 2015 Jul 31;(101):e52986. doi: 10.3791/52986.

20.

Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders.

Kristensen JH, Larsen L, Dasgupta B, Brodmerkel C, Curran M, Karsdal MA, Sand JM, Willumsen N, Knox AJ, Bolton CE, Johnson SR, Hägglund P, Svensson B, Leeming DJ.

Clin Biochem. 2015 Nov;48(16-17):1083-8. doi: 10.1016/j.clinbiochem.2015.07.009. Epub 2015 Jul 9.

PMID:
26164539
21.

Prostanoids as anti-inflammatory therapy: separating the good from the bad.

Knox AJ.

Thorax. 2015 Aug;70(8):711-2. doi: 10.1136/thoraxjnl-2015-207317. Epub 2015 Jun 17. No abstract available.

PMID:
26084959
22.

Accelerated extracellular matrix turnover during exacerbations of COPD.

Sand JM, Knox AJ, Lange P, Sun S, Kristensen JH, Leeming DJ, Karsdal MA, Bolton CE, Johnson SR.

Respir Res. 2015 Jun 11;16:69. doi: 10.1186/s12931-015-0225-3.

23.

Human airway smooth muscle cells secrete amphiregulin via bradykinin/COX-2/PGE2, inducing COX-2, CXCL8, and VEGF expression in airway epithelial cells.

Deacon K, Knox AJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 1;309(3):L237-49. doi: 10.1152/ajplung.00390.2014. Epub 2015 Jun 5.

24.

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis.

Barr HL, Halliday N, Cámara M, Barrett DA, Williams P, Forrester DL, Simms R, Smyth AR, Honeybourne D, Whitehouse JL, Nash EF, Dewar J, Clayton A, Knox AJ, Fogarty AW.

Eur Respir J. 2015 Oct;46(4):1046-54. doi: 10.1183/09031936.00225214. Epub 2015 May 28.

25.

Corrigendum. Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

Morris GE, Bridge JC, Eltboli OM, Lewis MP, Knox AJ, Aylott JW, Brightling CE, Ghaemmaghami AM, Rose FR.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L729. doi: 10.1152/ajplung.zh5-6728-corr.2015. No abstract available.

26.

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET.

Clifford RL, Patel JK, John AE, Tatler AL, Mazengarb L, Brightling CE, Knox AJ.

Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L962-72. doi: 10.1152/ajplung.00021.2015. Epub 2015 Feb 20.

27.

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial.

John ME, Cockcroft JR, McKeever TM, Coward WR, Shale DJ, Johnson SR, Thornton JG, Harrison TW, Knox AJ, Bolton CE.

Int J Chron Obstruct Pulmon Dis. 2015 Jan 29;10:211-21. doi: 10.2147/COPD.S76061. eCollection 2015.

28.

Mammalian Ste20-like kinase 4 promotes pituitary cell proliferation and survival under hypoxia.

Xiong W, Knox AJ, Xu M, Kiseljak-Vassiliades K, Colgan SP, Brodsky KS, Kleinschmidt-Demasters BK, Lillehei KO, Wierman ME.

Mol Endocrinol. 2015 Mar;29(3):460-72. doi: 10.1210/me.2014-1332. Epub 2015 Feb 4.

29.

β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.

O'Boyle NM, Pollock JK, Carr M, Knox AJ, Nathwani SM, Wang S, Caboni L, Zisterer DM, Meegan MJ.

J Med Chem. 2014 Nov 26;57(22):9370-82. doi: 10.1021/jm500670d. Epub 2014 Nov 17.

PMID:
25369367
30.

Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.

Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox AJ, Asada Y, Wierman ME, Hirata K, Rikitake Y.

PLoS One. 2014 Sep 24;9(9):e107236. doi: 10.1371/journal.pone.0107236. eCollection 2014.

31.

Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease.

Knox AJ, Scaling AL, Pinto MP, Bliesner BS, Haughian JM, Abdel-Hafiz HA, Horwitz KB.

Breast Cancer Res. 2014 Aug 13;16(4):418. doi: 10.1186/s13058-014-0418-6.

32.

A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells.

Morris GE, Bridge JC, Brace LA, Knox AJ, Aylott JW, Brightling CE, Ghaemmaghami AM, Rose FR.

Biofabrication. 2014 Sep;6(3):035014. doi: 10.1088/1758-5082/6/3/035014. Epub 2014 Jun 13.

PMID:
24925127
33.

Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

Morris GE, Bridge JC, Eltboli OM, Lewis MP, Knox AJ, Aylott JW, Brightling CE, Ghaemmaghami AM, Rose FR.

Am J Physiol Lung Cell Mol Physiol. 2014 Jul 1;307(1):L38-47. doi: 10.1152/ajplung.00318.2013. Epub 2014 May 2. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L729. Lewis, M P [added].

34.

A promoter-level mammalian expression atlas.

FANTOM Consortium and the RIKEN PMI and CLST (DGT), Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, Bertin N, Jørgensen M, Dimont E, Arner E, Schmidl C, Schaefer U, Medvedeva YA, Plessy C, Vitezic M, Severin J, Semple C, Ishizu Y, Young RS, Francescatto M, Alam I, Albanese D, Altschuler GM, Arakawa T, Archer JA, Arner P, Babina M, Rennie S, Balwierz PJ, Beckhouse AG, Pradhan-Bhatt S, Blake JA, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Burroughs AM, Califano A, Cannistraci CV, Carbajo D, Chen Y, Chierici M, Ciani Y, Clevers HC, Dalla E, Davis CA, Detmar M, Diehl AD, Dohi T, Drabløs F, Edge AS, Edinger M, Ekwall K, Endoh M, Enomoto H, Fagiolini M, Fairbairn L, Fang H, Farach-Carson MC, Faulkner GJ, Favorov AV, Fisher ME, Frith MC, Fujita R, Fukuda S, Furlanello C, Furino M, Furusawa J, Geijtenbeek TB, Gibson AP, Gingeras T, Goldowitz D, Gough J, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Harbers M, Harshbarger J, Hasegawa A, Hasegawa Y, Hashimoto T, Herlyn M, Hitchens KJ, Ho Sui SJ, Hofmann OM, Hoof I, Hori F, Huminiecki L, Iida K, Ikawa T, Jankovic BR, Jia H, Joshi A, Jurman G, Kaczkowski B, Kai C, Kaida K, Kaiho A, Kajiyama K, Kanamori-Katayama M, Kasianov AS, Kasukawa T, Katayama S, Kato S, Kawaguchi S, Kawamoto H, Kawamura YI, Kawashima T, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klinken SP, Knox AJ, Kojima M, Kojima S, Kondo N, Koseki H, Koyasu S, Krampitz S, Kubosaki A, Kwon AT, Laros JF, Lee W, Lennartsson A, Li K, Lilje B, Lipovich L, Mackay-Sim A, Manabe R, Mar JC, Marchand B, Mathelier A, Mejhert N, Meynert A, Mizuno Y, de Lima Morais DA, Morikawa H, Morimoto M, Moro K, Motakis E, Motohashi H, Mummery CL, Murata M, Nagao-Sato S, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nakazato K, van Nimwegen E, Ninomiya N, Nishiyori H, Noma S, Noma S, Noazaki T, Ogishima S, Ohkura N, Ohimiya H, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Pain A, Passier R, Patrikakis M, Persson H, Piazza S, Prendergast JG, Rackham OJ, Ramilowski JA, Rashid M, Ravasi T, Rizzu P, Roncador M, Roy S, Rye MB, Saijyo E, Sajantila A, Saka A, Sakaguchi S, Sakai M, Sato H, Savvi S, Saxena A, Schneider C, Schultes EA, Schulze-Tanzil GG, Schwegmann A, Sengstag T, Sheng G, Shimoji H, Shimoni Y, Shin JW, Simon C, Sugiyama D, Sugiyama T, Suzuki M, Suzuki N, Swoboda RK, 't Hoen PA, Tagami M, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tatum Z, Thompson M, Toyodo H, Toyoda T, Valen E, van de Wetering M, van den Berg LM, Verado R, Vijayan D, Vorontsov IE, Wasserman WW, Watanabe S, Wells CA, Winteringham LN, Wolvetang E, Wood EJ, Yamaguchi Y, Yamamoto M, Yoneda M, Yonekura Y, Yoshida S, Zabierowski SE, Zhang PG, Zhao X, Zucchelli S, Summers KM, Suzuki H, Daub CO, Kawai J, Heutink P, Hide W, Freeman TC, Lenhard B, Bajic VB, Taylor MS, Makeev VJ, Sandelin A, Hume DA, Carninci P, Hayashizaki Y.

Nature. 2014 Mar 27;507(7493):462-70. doi: 10.1038/nature13182.

35.

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.

Coward WR, Feghali-Bostwick CA, Jenkins G, Knox AJ, Pang L.

FASEB J. 2014 Jul;28(7):3183-96. doi: 10.1096/fj.13-241760. Epub 2014 Mar 20.

36.

Mast cell migration to airway smooth muscle in asthma. Can we Gro(w) something to block the attraction?

Lagan AL, Knox AJ.

Clin Exp Allergy. 2014 Mar;44(3):302-3. doi: 10.1111/cea.12262. No abstract available.

PMID:
24588862
37.

Functional consequences of AXL sequence variants in hypogonadotropic hypogonadism.

Salian-Mehta S, Xu M, Knox AJ, Plummer L, Slavov D, Taylor M, Bevers S, Hodges RS, Crowley WF Jr, Wierman ME.

J Clin Endocrinol Metab. 2014 Apr;99(4):1452-60. doi: 10.1210/jc.2013-3426. Epub 2014 Jan 29.

38.

Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation.

Dunny E, Doherty W, Evans P, Malthouse JP, Nolan D, Knox AJ.

J Med Chem. 2013 Sep 12;56(17):6638-50. doi: 10.1021/jm400294w. Epub 2013 Sep 3.

PMID:
23952916
39.

Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening.

Hintersteiner M, Knox AJ, Mudd G, Auer M.

J Chem Biol. 2012 Apr;5(2):63-79. doi: 10.1007/s12154-011-0071-9. Epub 2012 Jan 3.

40.

Inhibition of polyadenylation reduces inflammatory gene induction.

Kondrashov A, Meijer HA, Barthet-Barateig A, Parker HN, Khurshid A, Tessier S, Sicard M, Knox AJ, Pang L, De Moor CH.

RNA. 2012 Dec;18(12):2236-50. doi: 10.1261/rna.032391.112. Epub 2012 Nov 1.

41.

Future bronchodilator therapy: a bitter pill to swallow?

Clifford RL, Knox AJ.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec 1;303(11):L953-5. doi: 10.1152/ajplung.00303.2012. Epub 2012 Sep 28.

42.

Elevated SP-1 transcription factor expression and activity drives basal and hypoxia-induced vascular endothelial growth factor (VEGF) expression in non-small cell lung cancer.

Deacon K, Onion D, Kumari R, Watson SA, Knox AJ.

J Biol Chem. 2012 Nov 16;287(47):39967-81. doi: 10.1074/jbc.M112.397042. Epub 2012 Sep 18.

43.

Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study.

Forrester DL, Knox AJ, Smyth AR, Fogarty AW.

J Cyst Fibros. 2013 May;12(3):284-9. doi: 10.1016/j.jcf.2012.08.008. Epub 2012 Sep 5.

44.

CCR3 induced-p42/44 MAPK activation protects against staurosporine induced-DNA fragmentation but not apoptosis in airway smooth muscle cells.

Markwick LJ, Clements D, Roberts ME, Ceresa CC, Knox AJ, Johnson SR.

Clin Exp Allergy. 2012 Jul;42(7):1040-50. doi: 10.1111/j.1365-2222.2012.04019.x.

PMID:
22702503
45.

Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma.

Clifford RL, John AE, Brightling CE, Knox AJ.

J Immunol. 2012 Jul 15;189(2):819-31. doi: 10.4049/jimmunol.1103641. Epub 2012 Jun 11.

46.

Reprimo (RPRM) is a novel tumor suppressor in pituitary tumors and regulates survival, proliferation, and tumorigenicity.

Xu M, Knox AJ, Michaelis KA, Kiseljak-Vassiliades K, Kleinschmidt-DeMasters BK, Lillehei KO, Wierman ME.

Endocrinology. 2012 Jul;153(7):2963-73. doi: 10.1210/en.2011-2021. Epub 2012 May 4.

47.

Ciclesonide inhibits TNFα- and IL-1β-induced monocyte chemotactic protein-1 (MCP-1/CCL2) secretion from human airway smooth muscle cells.

Patel JK, Clifford RL, Deacon K, Knox AJ.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 15;302(8):L785-92. doi: 10.1152/ajplung.00257.2011. Epub 2012 Jan 13.

48.

Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma.

Tatler AL, John AE, Jolly L, Habgood A, Porte J, Brightling C, Knox AJ, Pang L, Sheppard D, Huang X, Jenkins G.

J Immunol. 2011 Dec 1;187(11):6094-107. doi: 10.4049/jimmunol.1003507. Epub 2011 Oct 24.

49.

Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90.

O'Boyle NM, Knox AJ, Price TT, Williams DC, Zisterer DM, Lloyd DG, Meegan MJ.

Bioorg Med Chem. 2011 Oct 15;19(20):6055-68. doi: 10.1016/j.bmc.2011.08.048. Epub 2011 Aug 25.

PMID:
21920765
50.

Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastrophe.

O'Boyle NM, Carr M, Greene LM, Keely NO, Knox AJ, McCabe T, Lloyd DG, Zisterer DM, Meegan MJ.

Eur J Med Chem. 2011 Sep;46(9):4595-607. doi: 10.1016/j.ejmech.2011.07.039. Epub 2011 Jul 28.

PMID:
21840628

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