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Items: 1 to 50 of 224

1.

Changes in the molecular and functional phenotype of bovine monocytes during T. parva infection.

Bastos RG, Sears K, Dinkel KD, Knowles DP, Fry LM.

Infect Immun. 2019 Sep 30. pii: IAI.00703-19. doi: 10.1128/IAI.00703-19. [Epub ahead of print]

2.

Mycoplasma ovis infection in domestic sheep (Ovis aries) in the United States: Prevalence, distribution, associated risk factors, and associated outcomes.

Urie NJ, Highland MA, Knowles DP, Branan MA, Herndon DR, Marshall KL.

Prev Vet Med. 2019 Nov 1;171:104750. doi: 10.1016/j.prevetmed.2019.104750. Epub 2019 Aug 24.

3.

Infection dynamics of Theileria equi and Theileria haneyi, a newly discovered apicomplexan of the horse.

Sears KP, Kappmeyer LS, Wise LN, Silva M, Ueti MW, White S, Reif KE, Knowles DP.

Vet Parasitol. 2019 Jul;271:68-75. doi: 10.1016/j.vetpar.2019.06.009. Epub 2019 Jun 12.

PMID:
31303207
4.

Molecular and Antigenic Properties of Mammalian Cell-Expressed Theileria parva Antigen Tp9.

Bastos RG, Franceschi V, Tebaldi G, Connelley T, Morrison WI, Knowles DP, Donofrio G, Fry LM.

Front Immunol. 2019 Apr 29;10:897. doi: 10.3389/fimmu.2019.00897. eCollection 2019.

5.

A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle.

Williams LBA, Fry LM, Herndon DR, Franceschi V, Schneider DA, Donofrio G, Knowles DP.

PLoS One. 2019 Apr 19;14(4):e0215605. doi: 10.1371/journal.pone.0215605. eCollection 2019.

6.

Gene gun DNA immunization of cattle induces humoral and CD4 T-cell-mediated immune responses against the Theileria parva polymorphic immunodominant molecule.

Fry LM, Bastos RG, Stone BC, Williams LB, Knowles DP, Murphy SC.

Vaccine. 2019 Mar 14;37(12):1546-1553. doi: 10.1016/j.vaccine.2019.02.009. Epub 2019 Feb 16.

7.

Evolution and diversity of the EMA families of the divergent equid parasites, Theileria equi and T. haneyi.

Wise LN, Kappmeyer LS, Knowles DP, White SN.

Infect Genet Evol. 2019 Mar;68:153-160. doi: 10.1016/j.meegid.2018.12.020. Epub 2018 Dec 18.

PMID:
30576837
8.

Evaluation of glycoprotein Ov8 as a potential antigen for an OvHV-2-specific diagnostic assay.

Alhajri SM, Cunha CW, Knowles DP, Li H, Taus NS.

PLoS One. 2018 Jul 2;13(7):e0200130. doi: 10.1371/journal.pone.0200130. eCollection 2018.

9.

Discovery of a novel species, Theileria haneyi n. sp., infective to equids, highlights exceptional genomic diversity within the genus Theileria: implications for apicomplexan parasite surveillance.

Knowles DP, Kappmeyer LS, Haney D, Herndon DR, Fry LM, Munro JB, Sears K, Ueti MW, Wise LN, Silva M, Schneider DA, Grause J, White SN, Tretina K, Bishop RP, Odongo DO, Pelzel-McCluskey AM, Scoles GA, Mealey RH, Silva JC.

Int J Parasitol. 2018 Aug;48(9-10):679-690. doi: 10.1016/j.ijpara.2018.03.010. Epub 2018 Jun 6.

10.

Assessment of Draxxin® (tulathromycin) as an inhibitor of in vitro growth of Babesia bovis, Babesia bigemina and Theileria equi.

Silva MG, Villarino NF, Knowles DP, Suarez CE.

Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):265-270. doi: 10.1016/j.ijpddr.2018.04.004. Epub 2018 Apr 17.

11.

Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid.

Silva MG, Knowles DP, Mazuz ML, Cooke BM, Suarez CE.

Sci Rep. 2018 Apr 17;8(1):6096. doi: 10.1038/s41598-018-23010-4.

12.

Exercise-induced pulmonary hemorrhage in barrel racing horses in the Pacific Northwest region of the United States.

Gold JR, Knowles DP, Coffey T, Bayly WM.

J Vet Intern Med. 2018 Mar;32(2):839-845. doi: 10.1111/jvim.15066. Epub 2018 Feb 20.

13.

Domestic sheep show average Coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak and lack detectable shedding by placental, vaginal, and fecal routes.

Oliveira RD, Mousel MR, Pabilonia KL, Highland MA, Taylor JB, Knowles DP, White SN.

PLoS One. 2017 Nov 15;12(11):e0188054. doi: 10.1371/journal.pone.0188054. eCollection 2017.

14.

Verification of post-chemotherapeutic clearance of Theileria equi through concordance of nested PCR and immunoblot.

Wise LN, Kappmeyer LS, Silva MG, White SN, Grause JF, Knowles DP.

Ticks Tick Borne Dis. 2018 Feb;9(2):135-140. doi: 10.1016/j.ttbdis.2017.08.007. Epub 2017 Aug 25.

PMID:
28887100
15.

Assessment and optimization of Theileria parva sporozoite full-length p67 antigen expression in mammalian cells.

Tebaldi G, Williams LB, Verna AE, Macchi F, Franceschi V, Fry LM, Knowles DP, Donofrio G.

PLoS Negl Trop Dis. 2017 Aug 11;11(8):e0005803. doi: 10.1371/journal.pntd.0005803. eCollection 2017 Aug.

16.

Underdominant KCC3b R31I association with blood sodium concentration in domestic sheep suggests role in oligomer function.

White SN, Oliveira RD, Mousel MR, Gonzalez MV, Highland MA, Herndon MK, Taylor JB, Knowles DP.

Anim Genet. 2017 Oct;48(5):626-627. doi: 10.1111/age.12585. Epub 2017 Jul 27. No abstract available.

17.

Inhibition of the in vitro growth of Babesia bigemina, Babesia caballi and Theileria equi parasites by trifluralin analogues.

G Silva M, Knowles DP, Antunes S, Domingos A, Esteves MA, Suarez CE.

Ticks Tick Borne Dis. 2017 Jun;8(4):593-597. doi: 10.1016/j.ttbdis.2017.04.002. Epub 2017 Apr 10.

18.

Transfected Babesia bovis Expressing a Tick GST as a Live Vector Vaccine.

Oldiges DP, Laughery JM, Tagliari NJ, Leite Filho RV, Davis WC, da Silva Vaz I Jr, Termignoni C, Knowles DP, Suarez CE.

PLoS Negl Trop Dis. 2016 Dec 2;10(12):e0005152. doi: 10.1371/journal.pntd.0005152. eCollection 2016 Dec.

19.

BoHV-4-based vector delivering Ebola virus surface glycoprotein.

Rosamilia A, Jacca S, Tebaldi G, Tiberti S, Franceschi V, Macchi F, Cavirani S, Kobinger G, Knowles DP, Donofrio G.

J Transl Med. 2016 Nov 24;14(1):325.

21.

Comparative Bioinformatics Analysis of Transcription Factor Genes Indicates Conservation of Key Regulatory Domains among Babesia bovis, Babesia microti, and Theileria equi.

Alzan HF, Knowles DP, Suarez CE.

PLoS Negl Trop Dis. 2016 Nov 10;10(11):e0004983. doi: 10.1371/journal.pntd.0004983. eCollection 2016 Nov. Review.

22.

Expression of 6-Cys Gene Superfamily Defines Babesia bovis Sexual Stage Development within Rhipicephalus microplus.

Alzan HF, Lau AO, Knowles DP, Herndon DR, Ueti MW, Scoles GA, Kappmeyer LS, Suarez CE.

PLoS One. 2016 Sep 26;11(9):e0163791. doi: 10.1371/journal.pone.0163791. eCollection 2016.

23.

Replacement of Glycoprotein B in Alcelaphine Herpesvirus 1 by Its Ovine Herpesvirus 2 Homolog : Implications in Vaccine Development for Sheep-Associated Malignant Catarrhal Fever.

Cunha CW, Taus NS, Dewals BG, Vanderplasschen A, Knowles DP, Li H.

mSphere. 2016 Aug 3;1(4). pii: e00108-16. doi: 10.1128/mSphere.00108-16. eCollection 2016 Jul-Aug.

24.

Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry.

Highland MA, Schneider DA, White SN, Madsen-Bouterse SA, Knowles DP, Davis WC.

Comp Immunol Microbiol Infect Dis. 2016 Jun;46:40-6. doi: 10.1016/j.cimid.2016.04.006. Epub 2016 Apr 14.

PMID:
27260809
25.

East Coast Fever Caused by Theileria parva Is Characterized by Macrophage Activation Associated with Vasculitis and Respiratory Failure.

Fry LM, Schneider DA, Frevert CW, Nelson DD, Morrison WI, Knowles DP.

PLoS One. 2016 May 19;11(5):e0156004. doi: 10.1371/journal.pone.0156004. eCollection 2016.

26.

Absolute Quantification of the Host-To-Parasite DNA Ratio in Theileria parva-Infected Lymphocyte Cell Lines.

Gotia HT, Munro JB, Knowles DP, Daubenberger CA, Bishop RP, Silva JC.

PLoS One. 2016 Mar 1;11(3):e0150401. doi: 10.1371/journal.pone.0150401. eCollection 2016.

27.

Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed dependent.

Mousel MR, White SN, Herndon DR, Reynolds JO, Gonzalez MV, Johnson WC, Ueti MW, Taylor JB, Knowles DP.

Anim Genet. 2016 Feb;47(1):136-7. doi: 10.1111/age.12381. Epub 2015 Dec 20. No abstract available.

28.

Sensitive and specific detection of classical scrapie prions in the brains of goats by real-time quaking-induced conversion.

Dassanayake RP, Orrú CD, Hughson AG, Caughey B, Graça T, Zhuang D, Madsen-Bouterse SA, Knowles DP, Schneider DA.

J Gen Virol. 2016 Mar;97(3):803-12. doi: 10.1099/jgv.0.000367. Epub 2015 Dec 10.

29.

Theileria equi isolates vary in susceptibility to imidocarb dipropionate but demonstrate uniform in vitro susceptibility to a bumped kinase inhibitor.

Hines SA, Ramsay JD, Kappmeyer LS, Lau AO, Ojo KK, Van Voorhis WC, Knowles DP, Mealey RH.

Parasit Vectors. 2015 Jan 20;8:33. doi: 10.1186/s13071-014-0611-6.

30.

Experimental transmission of equine hepacivirus in horses as a model for hepatitis C virus.

Ramsay JD, Evanoff R, Wilkinson TE Jr, Divers TJ, Knowles DP, Mealey RH.

Hepatology. 2015 May;61(5):1533-46. doi: 10.1002/hep.27689. Epub 2015 Feb 24.

PMID:
25580897
31.

Antibodies to ovine herpesvirus 2 glycoproteins decrease virus infectivity and prevent malignant catarrhal fever in rabbits.

Cunha CW, Knowles DP, Taus NS, O'Toole D, Nicola AV, Aguilar HC, Li H.

Vet Microbiol. 2015 Feb 25;175(2-4):349-55. doi: 10.1016/j.vetmic.2014.11.026. Epub 2014 Dec 9.

PMID:
25542288
32.

Malignant catarrhal fever: inching toward understanding.

Li H, Cunha CW, Taus NS, Knowles DP.

Annu Rev Anim Biosci. 2014 Feb;2:209-33. doi: 10.1146/annurev-animal-022513-114156. Epub 2013 Oct 18. Review.

PMID:
25384141
33.

Equine piroplasmosis.

Wise LN, Pelzel-McCluskey AM, Mealey RH, Knowles DP.

Vet Clin North Am Equine Pract. 2014 Dec;30(3):677-93. doi: 10.1016/j.cveq.2014.08.008. Epub 2014 Oct 6. Review.

PMID:
25300637
34.

Targeted surface expression of an exogenous antigen in stably transfected Babesia bovis.

Laughery JM, Knowles DP, Schneider DA, Bastos RG, McElwain TF, Suarez CE.

PLoS One. 2014 May 19;9(5):e97890. doi: 10.1371/journal.pone.0097890. eCollection 2014.

35.

Association analysis of variant near ZNF389 with ewe cumulative production in three sheep breeds.

White SN, Mousel MR, Gonzalez MV, Highland MA, Herrmann-Hoesing LM, Taylor JB, Knowles DP.

Anim Genet. 2014 Aug;45(4):613-4. doi: 10.1111/age.12161. Epub 2014 Apr 11. No abstract available.

36.

Improved diagnostic performance of a commercial Anaplasma antibody competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5-glutathione S-transferase fusion protein as antigen.

Chung C, Wilson C, Bandaranayaka-Mudiyanselage CB, Kang E, Adams DS, Kappmeyer LS, Knowles DP, McElwain TF, Evermann JF, Ueti MW, Scoles GA, Lee SS, McGuire TC.

J Vet Diagn Invest. 2014 Jan;26(1):61-71. doi: 10.1177/1040638713511813. Epub 2013 Dec 6.

PMID:
24318928
37.

Deletion variant near ZNF389 is associated with control of ovine lentivirus in multiple sheep flocks.

White SN, Mousel MR, Reynolds JO, Herrmann-Hoesing LM, Knowles DP.

Anim Genet. 2014 Apr;45(2):297-300. doi: 10.1111/age.12107. Epub 2013 Dec 5.

38.

Lymphocytes and macrophages are infected by Theileria equi, but T cells and B cells are not required to establish infection in vivo.

Ramsay JD, Ueti MW, Johnson WC, Scoles GA, Knowles DP, Mealey RH.

PLoS One. 2013 Oct 7;8(10):e76996. doi: 10.1371/journal.pone.0076996. eCollection 2013.

39.

Serum antibodies from a subset of horses positive for Babesia caballi by competitive enzyme-linked immunosorbent assay demonstrate a protein recognition pattern that is not consistent with infection.

Awinda PO, Mealey RH, Williams LB, Conrad PA, Packham AE, Reif KE, Grause JF, Pelzel-McCluskey AM, Chung C, Bastos RG, Kappmeyer LS, Howe DK, Ness SL, Knowles DP, Ueti MW.

Clin Vaccine Immunol. 2013 Nov;20(11):1752-7. doi: 10.1128/CVI.00479-13. Epub 2013 Sep 18.

40.

Review of equine piroplasmosis.

Wise LN, Kappmeyer LS, Mealey RH, Knowles DP.

J Vet Intern Med. 2013 Nov-Dec;27(6):1334-46. doi: 10.1111/jvim.12168. Epub 2013 Aug 28. Review.

41.

Differential expression of three members of the multidomain adhesion CCp family in Babesia bigemina, Babesia bovis and Theileria equi.

Bastos RG, Suarez CE, Laughery JM, Johnson WC, Ueti MW, Knowles DP.

PLoS One. 2013 Jul 3;8(7):e67765. doi: 10.1371/journal.pone.0067765. Print 2013.

42.
43.

Repertoire of Theileria equi immunodominant antigens bound by equine antibody.

Silva MG, Graça T, Suarez CE, Knowles DP.

Mol Biochem Parasitol. 2013 Apr;188(2):109-15. doi: 10.1016/j.molbiopara.2013.03.002. Epub 2013 Mar 26.

PMID:
23541863
44.

Are rabbits a suitable model to study sheep-associated malignant catarrhal fever in susceptible hosts?

Cunha CW, O'Toole D, Taus NS, Knowles DP, Li H.

Vet Microbiol. 2013 May 3;163(3-4):358-63. doi: 10.1016/j.vetmic.2013.01.002. Epub 2013 Jan 23.

PMID:
23394795
45.

Development of an in vivo system to measure antibody-blocking of ovine herpesvirus 2 entry.

Li H, Cunha CW, O'Toole D, Nicola AV, Knowles DP, Taus NS.

J Virol Methods. 2013 Mar;188(1-2):104-7. doi: 10.1016/j.jviromet.2012.12.008. Epub 2012 Dec 26.

PMID:
23274755
46.

Efficacy of imidocarb dipropionate in eliminating Theileria equi from experimentally infected horses.

Grause JF, Ueti MW, Nelson JT, Knowles DP, Kappmeyer LS, Bunn TO.

Vet J. 2013 Jun;196(3):541-6. doi: 10.1016/j.tvjl.2012.10.025. Epub 2012 Nov 28.

PMID:
23199699
47.

Comparative genomic analysis and phylogenetic position of Theileria equi.

Kappmeyer LS, Thiagarajan M, Herndon DR, Ramsay JD, Caler E, Djikeng A, Gillespie JJ, Lau AO, Roalson EH, Silva JC, Silva MG, Suarez CE, Ueti MW, Nene VM, Mealey RH, Knowles DP, Brayton KA.

BMC Genomics. 2012 Nov 9;13:603. doi: 10.1186/1471-2164-13-603.

48.

Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.

White SN, Mousel MR, Herrmann-Hoesing LM, Reynolds JO, Leymaster KA, Neibergs HL, Lewis GS, Knowles DP.

PLoS One. 2012;7(10):e47829. doi: 10.1371/journal.pone.0047829. Epub 2012 Oct 17.

49.

Role of Bibersteinia trehalosi, respiratory syncytial virus, and parainfluenza-3 virus in bighorn sheep pneumonia.

Dassanayake RP, Shanthalingam S, Subramaniam R, Herndon CN, Bavananthasivam J, Haldorson GJ, Foreyt WJ, Evermann JF, Herrmann-Hoesing LM, Knowles DP, Srikumaran S.

Vet Microbiol. 2013 Feb 22;162(1):166-72. doi: 10.1016/j.vetmic.2012.08.029. Epub 2012 Sep 7.

PMID:
23025980
50.

Re-emergence of the apicomplexan Theileria equi in the United States: elimination of persistent infection and transmission risk.

Ueti MW, Mealey RH, Kappmeyer LS, White SN, Kumpula-McWhirter N, Pelzel AM, Grause JF, Bunn TO, Schwartz A, Traub-Dargatz JL, Hendrickson A, Espy B, Guthrie AJ, Fowler WK, Knowles DP.

PLoS One. 2012;7(9):e44713. doi: 10.1371/journal.pone.0044713. Epub 2012 Sep 6.

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