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Behavioural activation versus guided self-help for depression in adults with learning disabilities: the BeatIt RCT.

Jahoda A, Hastings R, Hatton C, Cooper SA, McMeekin N, Dagnan D, Appleton K, Scott K, Fulton L, Jones R, McConnachie A, Zhang R, Knight R, Knowles D, Williams C, Briggs A, Melville C.

Health Technol Assess. 2018 Sep;22(53):1-130. doi: 10.3310/hta22530.


Supporting people with intellectual disabilities in psychological therapies for depression: A qualitative analysis of supporters' experiences.

Scott K, Hatton C, Knight R, Singer K, Knowles D, Dagnan D, Hastings RP, Appleton K, Cooper SA, Melville C, Jones R, Williams C, Jahoda A.

J Appl Res Intellect Disabil. 2018 Sep 28. doi: 10.1111/jar.12529. [Epub ahead of print]


The feasibility and acceptability of a novel anxiety in bipolar disorder intervention compared to treatment as usual: A randomized controlled trial.

Jones SH, Knowles D, Tyler E, Holland F, Peters S, Lobban F, Langshaw B, Hilton C, Long R, Gantt K, Owen R, Roberts C, Riste L.

Depress Anxiety. 2018 Oct;35(10):953-965. doi: 10.1002/da.22781. Epub 2018 Jul 19.


Evaluation of glycoprotein Ov8 as a potential antigen for an OvHV-2-specific diagnostic assay.

Alhajri SM, Cunha CW, Knowles DP, Li H, Taus NS.

PLoS One. 2018 Jul 2;13(7):e0200130. doi: 10.1371/journal.pone.0200130. eCollection 2018.


Discovery of a novel species, Theileria haneyi n. sp., infective to equids, highlights exceptional genomic diversity within the genus Theileria: implications for apicomplexan parasite surveillance.

Knowles DP, Kappmeyer LS, Haney D, Herndon DR, Fry LM, Munro JB, Sears K, Ueti MW, Wise LN, Silva M, Schneider DA, Grause J, White SN, Tretina K, Bishop RP, Odongo DO, Pelzel-McCluskey AM, Scoles GA, Mealey RH, Silva JC.

Int J Parasitol. 2018 Aug;48(9-10):679-690. doi: 10.1016/j.ijpara.2018.03.010. Epub 2018 Jun 6.


Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes.

Knowles DA, Burrows CK, Blischak JD, Patterson KM, Serie DJ, Norton N, Ober C, Pritchard JK, Gilad Y.

Elife. 2018 May 8;7. pii: e33480. doi: 10.7554/eLife.33480.


Assessment of Draxxin® (tulathromycin) as an inhibitor of in vitro growth of Babesia bovis, Babesia bigemina and Theileria equi.

Silva MG, Villarino NF, Knowles DP, Suarez CE.

Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):265-270. doi: 10.1016/j.ijpddr.2018.04.004. Epub 2018 Apr 17.


Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid.

Silva MG, Knowles DP, Mazuz ML, Cooke BM, Suarez CE.

Sci Rep. 2018 Apr 17;8(1):6096. doi: 10.1038/s41598-018-23010-4.


Interactions between genetic variation and cellular environment in skeletal muscle gene expression.

Taylor DL, Knowles DA, Scott LJ, Ramirez AH, Casale FP, Wolford BN, Guan L, Varshney A, Albanus RD, Parker SCJ, Narisu N, Chines PS, Erdos MR, Welch RP, Kinnunen L, Saramies J, Sundvall J, Lakka TA, Laakso M, Tuomilehto J, Koistinen HA, Stegle O, Boehnke M, Birney E, Collins FS.

PLoS One. 2018 Apr 16;13(4):e0195788. doi: 10.1371/journal.pone.0195788. eCollection 2018.


Exercise-induced pulmonary hemorrhage in barrel racing horses in the Pacific Northwest region of the United States.

Gold JR, Knowles DP, Coffey T, Bayly WM.

J Vet Intern Med. 2018 Mar;32(2):839-845. doi: 10.1111/jvim.15066. Epub 2018 Feb 20.


Impacts of licensed premises trading hour policies on alcohol-related harms.

Atkinson JA, Prodan A, Livingston M, Knowles D, O'Donnell E, Room R, Indig D, Page A, McDonnell G, Wiggers J.

Addiction. 2018 Jul;113(7):1244-1251. doi: 10.1111/add.14178. Epub 2018 Mar 2.


Annotation-free quantification of RNA splicing using LeafCutter.

Li YI, Knowles DA, Humphrey J, Barbeira AN, Dickinson SP, Im HK, Pritchard JK.

Nat Genet. 2018 Jan;50(1):151-158. doi: 10.1038/s41588-017-0004-9. Epub 2017 Dec 11.


Comparison of behavioural activation with guided self-help for treatment of depression in adults with intellectual disabilities: a randomised controlled trial.

Jahoda A, Hastings R, Hatton C, Cooper SA, Dagnan D, Zhang R, McConnachie A, McMeekin N, Appleton K, Jones R, Scott K, Fulton L, Knight R, Knowles D, Williams C, Briggs A, MacMahon K, Lynn H, Smith I, Thomas G, Melville C.

Lancet Psychiatry. 2017 Dec;4(12):909-919. doi: 10.1016/S2215-0366(17)30426-1. Epub 2017 Nov 16.


Domestic sheep show average Coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak and lack detectable shedding by placental, vaginal, and fecal routes.

Oliveira RD, Mousel MR, Pabilonia KL, Highland MA, Taylor JB, Knowles DP, White SN.

PLoS One. 2017 Nov 15;12(11):e0188054. doi: 10.1371/journal.pone.0188054. eCollection 2017.


Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression.

Calderon D, Bhaskar A, Knowles DA, Golan D, Raj T, Fu AQ, Pritchard JK.

Am J Hum Genet. 2017 Nov 2;101(5):686-699. doi: 10.1016/j.ajhg.2017.09.009. Epub 2017 Oct 26.


Harnessing advances in computer simulation to inform policy and planning to reduce alcohol-related harms.

Atkinson JA, Knowles D, Wiggers J, Livingston M, Room R, Prodan A, McDonnell G, O'Donnell E, Jones S, Haber PS, Muscatello D, Ezard N, Phung N, Freebairn L, Indig D, Rychetnik L, Ananthapavan J, Wutzke S; alcohol modelling consortium.

Int J Public Health. 2018 May;63(4):537-546. doi: 10.1007/s00038-017-1041-y. Epub 2017 Oct 19.


Verification of post-chemotherapeutic clearance of Theileria equi through concordance of nested PCR and immunoblot.

Wise LN, Kappmeyer LS, Silva MG, White SN, Grause JF, Knowles DP.

Ticks Tick Borne Dis. 2018 Feb;9(2):135-140. doi: 10.1016/j.ttbdis.2017.08.007. Epub 2017 Aug 25.


Assessment and optimization of Theileria parva sporozoite full-length p67 antigen expression in mammalian cells.

Tebaldi G, Williams LB, Verna AE, Macchi F, Franceschi V, Fry LM, Knowles DP, Donofrio G.

PLoS Negl Trop Dis. 2017 Aug 11;11(8):e0005803. doi: 10.1371/journal.pntd.0005803. eCollection 2017 Aug.


Underdominant KCC3b R31I association with blood sodium concentration in domestic sheep suggests role in oligomer function.

White SN, Oliveira RD, Mousel MR, Gonzalez MV, Highland MA, Herndon MK, Taylor JB, Knowles DP.

Anim Genet. 2017 Oct;48(5):626-627. doi: 10.1111/age.12585. Epub 2017 Jul 27. No abstract available.


Allele-specific expression reveals interactions between genetic variation and environment.

Knowles DA, Davis JR, Edgington H, Raj A, Favé MJ, Zhu X, Potash JB, Weissman MM, Shi J, Levinson DF, Awadalla P, Mostafavi S, Montgomery SB, Battle A.

Nat Methods. 2017 Jul;14(7):699-702. doi: 10.1038/nmeth.4298. Epub 2017 May 22.


Shifting Quaternary migration patterns in the Bahamian archipelago: Evidence from the Zamia pumila complex at the northern limits of the Caribbean island biodiversity hotspot.

Salas-Leiva DE, Meerow AW, Calonje M, Francisco-Ortega J, Griffith MP, Nakamura K, Sánchez V, Knowles L, Knowles D.

Am J Bot. 2017 May;104(5):757-771. doi: 10.3732/ajb.1700054. Epub 2017 May 17.


Inhibition of the in vitro growth of Babesia bigemina, Babesia caballi and Theileria equi parasites by trifluralin analogues.

G Silva M, Knowles DP, Antunes S, Domingos A, Esteves MA, Suarez CE.

Ticks Tick Borne Dis. 2017 Jun;8(4):593-597. doi: 10.1016/j.ttbdis.2017.04.002. Epub 2017 Apr 10.


Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.

Becker LA, Huang B, Bieri G, Ma R, Knowles DA, Jafar-Nejad P, Messing J, Kim HJ, Soriano A, Auburger G, Pulst SM, Taylor JP, Rigo F, Gitler AD.

Nature. 2017 Apr 20;544(7650):367-371. doi: 10.1038/nature22038. Epub 2017 Apr 12.


Assessing Feasibility and Acceptability of Web-Based Enhanced Relapse Prevention for Bipolar Disorder (ERPonline): A Randomized Controlled Trial.

Lobban F, Dodd AL, Sawczuk AP, Asar O, Dagnan D, Diggle PJ, Griffiths M, Honary M, Knowles D, Long R, Morriss R, Parker R, Jones S.

J Med Internet Res. 2017 Mar 24;19(3):e85. doi: 10.2196/jmir.7008.


Building Research Capacity: Results of a Feasibility Study Using a Novel mHealth Epidemiological Data Collection System Within a Gestational Diabetes Population.

McLean A, Osgood N, Newstead-Angel J, Stanley K, Knowles D, van der Kamp W, Qian W, Dyck R.

Stud Health Technol Inform. 2017;234:228-232.


Batch effects and the effective design of single-cell gene expression studies.

Tung PY, Blischak JD, Hsiao CJ, Knowles DA, Burnett JE, Pritchard JK, Gilad Y.

Sci Rep. 2017 Jan 3;7:39921. doi: 10.1038/srep39921.


Transfected Babesia bovis Expressing a Tick GST as a Live Vector Vaccine.

Oldiges DP, Laughery JM, Tagliari NJ, Leite Filho RV, Davis WC, da Silva Vaz I Jr, Termignoni C, Knowles DP, Suarez CE.

PLoS Negl Trop Dis. 2016 Dec 2;10(12):e0005152. doi: 10.1371/journal.pntd.0005152. eCollection 2016 Dec.


BoHV-4-based vector delivering Ebola virus surface glycoprotein.

Rosamilia A, Jacca S, Tebaldi G, Tiberti S, Franceschi V, Macchi F, Cavirani S, Kobinger G, Knowles DP, Donofrio G.

J Transl Med. 2016 Nov 24;14(1):325.


Comparative Bioinformatics Analysis of Transcription Factor Genes Indicates Conservation of Key Regulatory Domains among Babesia bovis, Babesia microti, and Theileria equi.

Alzan HF, Knowles DP, Suarez CE.

PLoS Negl Trop Dis. 2016 Nov 10;10(11):e0004983. doi: 10.1371/journal.pntd.0004983. eCollection 2016 Nov. Review.


Small RNA Sequencing in Cells and Exosomes Identifies eQTLs and 14q32 as a Region of Active Export.

Tsang EK, Abell NS, Li X, Anaya V, Karczewski KJ, Knowles DA, Sierra RG, Smith KS, Montgomery SB.

G3 (Bethesda). 2017 Jan 5;7(1):31-39. doi: 10.1534/g3.116.036137.


Enhancing image quality in cleared tissue with adaptive optics.

Reinig MR, Novak SW, Tao X, Bentolila LA, Roberts DG, MacKenzie-Graham A, Godshalk SE, Raven MA, Knowles DW, Kubby J.

J Biomed Opt. 2016 Dec 1;21(12):121508. doi: 10.1117/1.JBO.21.12.121508.


Expression of 6-Cys Gene Superfamily Defines Babesia bovis Sexual Stage Development within Rhipicephalus microplus.

Alzan HF, Lau AO, Knowles DP, Herndon DR, Ueti MW, Scoles GA, Kappmeyer LS, Suarez CE.

PLoS One. 2016 Sep 26;11(9):e0163791. doi: 10.1371/journal.pone.0163791. eCollection 2016.


Corrigendum: Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.

Qiao X, He B, Chiu A, Knowles DM, Chadburn A, Cerutti A.

Nat Immunol. 2016 Sep 20;17(10):1235. doi: 10.1038/ni1016-1235a. No abstract available.


Replacement of Glycoprotein B in Alcelaphine Herpesvirus 1 by Its Ovine Herpesvirus 2 Homolog : Implications in Vaccine Development for Sheep-Associated Malignant Catarrhal Fever.

Cunha CW, Taus NS, Dewals BG, Vanderplasschen A, Knowles DP, Li H.

mSphere. 2016 Aug 3;1(4). pii: e00108-16. doi: 10.1128/mSphere.00108-16. eCollection 2016 Jul-Aug.


Design and methods of a social network isolation study for reducing respiratory infection transmission: The eX-FLU cluster randomized trial.

Aiello AE, Simanek AM, Eisenberg MC, Walsh AR, Davis B, Volz E, Cheng C, Rainey JJ, Uzicanin A, Gao H, Osgood N, Knowles D, Stanley K, Tarter K, Monto AS.

Epidemics. 2016 Jun;15:38-55. doi: 10.1016/j.epidem.2016.01.001. Epub 2016 Feb 1.


Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry.

Highland MA, Schneider DA, White SN, Madsen-Bouterse SA, Knowles DP, Davis WC.

Comp Immunol Microbiol Infect Dis. 2016 Jun;46:40-6. doi: 10.1016/j.cimid.2016.04.006. Epub 2016 Apr 14.


Impact of the X Chromosome and sex on regulatory variation.

Kukurba KR, Parsana P, Balliu B, Smith KS, Zappala Z, Knowles DA, Favé MJ, Davis JR, Li X, Zhu X, Potash JB, Weissman MM, Shi J, Kundaje A, Levinson DF, Awadalla P, Mostafavi S, Battle A, Montgomery SB.

Genome Res. 2016 Jun;26(6):768-77. doi: 10.1101/gr.197897.115. Epub 2016 Apr 21.


East Coast Fever Caused by Theileria parva Is Characterized by Macrophage Activation Associated with Vasculitis and Respiratory Failure.

Fry LM, Schneider DA, Frevert CW, Nelson DD, Morrison WI, Knowles DP.

PLoS One. 2016 May 19;11(5):e0156004. doi: 10.1371/journal.pone.0156004. eCollection 2016.


Assessment of Theileria equi and Babesia caballi infections in equine populations in Egypt by molecular, serological and hematological approaches.

Mahmoud MS, El-Ezz NT, Abdel-Shafy S, Nassar SA, El Namaky AH, Khalil WK, Knowles D, Kappmeyer L, Silva MG, Suarez CE.

Parasit Vectors. 2016 May 4;9:260. doi: 10.1186/s13071-016-1539-9.


Breast Cancer in the Bahamas in 2009-2011.

Mungrue K, Chase H, Gordon J, Knowles D, Lockhart K, Miller N, Morley T, Sealey L, Turner B.

Breast Cancer (Auckl). 2016 Apr 21;10:45-52. doi: 10.4137/BCBCR.S32792. eCollection 2016.


RNA splicing is a primary link between genetic variation and disease.

Li YI, van de Geijn B, Raj A, Knowles DA, Petti AA, Golan D, Gilad Y, Pritchard JK.

Science. 2016 Apr 29;352(6285):600-4. doi: 10.1126/science.aad9417. Epub 2016 Apr 28.


Absolute Quantification of the Host-To-Parasite DNA Ratio in Theileria parva-Infected Lymphocyte Cell Lines.

Gotia HT, Munro JB, Knowles DP, Daubenberger CA, Bishop RP, Silva JC.

PLoS One. 2016 Mar 1;11(3):e0150401. doi: 10.1371/journal.pone.0150401. eCollection 2016.


Removing large diameter acetabular cups with the Explant Acetabular Cup Removal System: A technique to maintain the centre of rotation.

Nesbitt P, Knowles D.

Ann R Coll Surg Engl. 2016 Apr;98(4):287. doi: 10.1308/rcsann.2016.0090. Epub 2016 Feb 29. No abstract available.


Alternatives to antibiotics-a pipeline portfolio review.

Czaplewski L, Bax R, Clokie M, Dawson M, Fairhead H, Fischetti VA, Foster S, Gilmore BF, Hancock RE, Harper D, Henderson IR, Hilpert K, Jones BV, Kadioglu A, Knowles D, Ólafsdóttir S, Payne D, Projan S, Shaunak S, Silverman J, Thomas CM, Trust TJ, Warn P, Rex JH.

Lancet Infect Dis. 2016 Feb;16(2):239-51. doi: 10.1016/S1473-3099(15)00466-1. Epub 2016 Jan 13. Review.


An Efficient Multiple-Testing Adjustment for eQTL Studies that Accounts for Linkage Disequilibrium between Variants.

Davis JR, Fresard L, Knowles DA, Pala M, Bustamante CD, Battle A, Montgomery SB.

Am J Hum Genet. 2016 Jan 7;98(1):216-24. doi: 10.1016/j.ajhg.2015.11.021. Epub 2015 Dec 31.


Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed dependent.

Mousel MR, White SN, Herndon DR, Reynolds JO, Gonzalez MV, Johnson WC, Ueti MW, Taylor JB, Knowles DP.

Anim Genet. 2016 Feb;47(1):136-7. doi: 10.1111/age.12381. Epub 2015 Dec 20. No abstract available.


Sensitive and specific detection of classical scrapie prions in the brains of goats by real-time quaking-induced conversion.

Dassanayake RP, Orrú CD, Hughson AG, Caughey B, Graça T, Zhuang D, Madsen-Bouterse SA, Knowles DP, Schneider DA.

J Gen Virol. 2016 Mar;97(3):803-12. doi: 10.1099/jgv.0.000367. Epub 2015 Dec 10.


EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis.

Ma J, Nie K, Redmond D, Liu Y, Elemento O, Knowles DM, Tam W.

Leukemia. 2016 Mar;30(3):594-604. doi: 10.1038/leu.2015.285. Epub 2015 Nov 4.

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