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Altered gait mechanics are associated with severity of chondropathy after hip arthroscopy for femoroacetabular impingement syndrome.

Brown-Taylor L, Wilson J, McNally M, Perry J, Jackson RD, Hewett TE, Ryan J, Knopp MV, Payne JE, Di Stasi S.

Gait Posture. 2019 Nov 11;77:175-181. doi: 10.1016/j.gaitpost.2019.11.003. [Epub ahead of print]


The influence of drug and polymer particle size on the in situ amorphization using microwave irradiation.

Hempel NJ, Knopp MM, Berthelsen R, Axel Zeitler J, Löbmann K.

Eur J Pharm Biopharm. 2020 Feb 5. pii: S0939-6411(20)30031-X. doi: 10.1016/j.ejpb.2020.01.019. [Epub ahead of print]


Evolution of a new function by fusion between phage DNA and a bacterial gene.

Warsi O, Knopp M, Surkov S, Hultqvist JJ, Andersson DI.

Mol Biol Evol. 2020 Jan 16. pii: msaa007. doi: 10.1093/molbev/msaa007. [Epub ahead of print]


Periodically rotated overlapping parallel lines with enhanced reconstruction acquisition to improve motion-induced artifacts in bladder cancer imaging: Initial findings.

Nguyen HT, Shah ZK, Mortazavi A, Pohar KS, Wei L, Zynger DL, Knopp MV.

Medicine (Baltimore). 2019 Oct;98(42):e17075. doi: 10.1097/MD.0000000000017075.


18F-Sodium fluoride PET/CT predicts overall survival in patients with advanced genitourinary malignancies treated with cabozantinib and nivolumab with or without ipilimumab.

Lim I, Lindenberg ML, Mena E, Verdini N, Shih JH, Mayfield C, Thompson R, Lin J, Vega A, Mallek M, Cadena J, Diaz C, Mortazavi A, Knopp M, Wright C, Stein M, Pal S, Choyke PL, Apolo AB.

Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):178-184. doi: 10.1007/s00259-019-04483-5. Epub 2019 Sep 14.


Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency.

Antonino RSCMQ, Ruggiero M, Song Z, Nascimento TL, Lima EM, Bohr A, Knopp MM, Löbmann K.

Int J Pharm X. 2019 Jul 22;1:100026. doi: 10.1016/j.ijpx.2019.100026. eCollection 2019 Dec.


The role interplay between mesoporous silica pore volume and surface area and their effect on drug loading capacity.

Bavnhøj CG, Knopp MM, Madsen CM, Löbmann K.

Int J Pharm X. 2019 Feb 22;1:100008. doi: 10.1016/j.ijpx.2019.100008. eCollection 2019 Dec.


Connectivity-based selection of optimal deep brain stimulation contacts: A feasibility study.

Krishna V, Sammartino F, Rabbani Q, Changizi B, Agrawal P, Deogaonkar M, Knopp M, Young N, Rezai A.

Ann Clin Transl Neurol. 2019 Jul;6(7):1142-1150. doi: 10.1002/acn3.784. Epub 2019 Jun 26.


Five-year follow-up of SWOG S0816: limitations and values of a PET-adapted approach with stage III/IV Hodgkin lymphoma.

Stephens DM, Li H, Schöder H, Straus DJ, Moskowitz CH, LeBlanc M, Rimsza LM, Bartlett NL, Evens AM, LaCasce AS, Barr PM, Knopp MV, Hsi ED, Leonard JP, Kahl BS, Smith SM, Friedberg JW.

Blood. 2019 Oct 10;134(15):1238-1246. doi: 10.1182/blood.2019000719.


Gadolinium Retention in the Brain: What Do We Need to Consider for Clinical Use?

Heverhagen JT, Knopp MV.

Invest Radiol. 2019 Aug;54(8):466-467. doi: 10.1097/RLI.0000000000000589. No abstract available.


Elusive data underlying debate at the prokaryote-eukaryote divide.

Gerlitz M, Knopp M, Kapust N, Xavier JC, Martin WF.

Biol Direct. 2018 Oct 3;13(1):21. doi: 10.1186/s13062-018-0221-x.


De Novo Emergence of Peptides That Confer Antibiotic Resistance.

Knopp M, Gudmundsdottir JS, Nilsson T, König F, Warsi O, Rajer F, Ädelroth P, Andersson DI.

mBio. 2019 Jun 4;10(3). pii: e00837-19. doi: 10.1128/mBio.00837-19.


MRI-based methodology to monitor the impact of positional changes on the airway caliber in obstructive sleep apnea patients.

Nguyen HT, Magalang U, Abduljalil A, Elias S, Schmalbrock P, Chandrasekaran P, Rojas S, Emmons K, Ribble D, Knopp MV.

Magn Reson Imaging. 2019 Sep;61:233-238. doi: 10.1016/j.mri.2019.05.039. Epub 2019 May 28.


Emerging Opportunities for Digital PET/CT to Advance Locoregional Therapy in Head and Neck Cancer.

Wright CL, Washington IR, Bhatt AD, Knopp MV.

Semin Radiat Oncol. 2019 Apr;29(2):93-101. doi: 10.1016/j.semradonc.2018.11.005. Review.


NCTN Assessment on Current Applications of Radiomics in Oncology.

Nie K, Al-Hallaq H, Li XA, Benedict SH, Sohn JW, Moran JM, Fan Y, Huang M, Knopp MV, Michalski JM, Monroe J, Obcemea C, Tsien CI, Solberg T, Wu J, Xia P, Xiao Y, El Naqa I.

Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):302-315. doi: 10.1016/j.ijrobp.2019.01.087. Epub 2019 Jan 31. Review.


Differential visualization of arterial and venous flow in deep inferior epigastric perforator imaging with vector-flow perforator Phase Contrast Angiography (pPCA).

Yang X, Chao AH, Miller MJ, Knopp MV.

J Plast Reconstr Aesthet Surg. 2019 Jan;72(1):137-171. doi: 10.1016/j.bjps.2018.10.006. Epub 2018 Nov 2. No abstract available.


Performance evaluation of the next generation solid-state digital photon counting PET/CT system.

Zhang J, Maniawski P, Knopp MV.

EJNMMI Res. 2018 Nov 6;8(1):97. doi: 10.1186/s13550-018-0448-7.


The Importance of Imaging in Radiation Oncology for National Clinical Trials Network Protocols.

FitzGerald TJ, Bishop-Jodoin M, Laurie F, O'Meara E, Davis C, Bogart J, Kalapurakal J, Siegel MJ, Chakravarthy B, Okunieff P, Haffty B, Michalski J, Ulin K, Followill DS, Kry S, Knopp M, Zhang J, Rosen D, Rosen M, Xiao Y, Schwartz L, Moni J, Cicchetti MG.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):775-782. doi: 10.1016/j.ijrobp.2018.08.039. Epub 2018 Oct 18. Review.


Integration of cardiac energetics, function and histology from isolated rat hearts perfused with doxorubicin and doxorubicin-ol; a model for use in drug safety evaluations.

Henderson KA, Borders RB, Ross JB, Abdulalil A, Gibbs S, Skowronek AJ, Knostman K, Bailey J, Smith J, Vinci T, Wood B, Knopp MV, Roche BM.

J Pharmacol Toxicol Methods. 2018 Nov - Dec;94(Pt 2):54-63. doi: 10.1016/j.vascn.2018.08.004. Epub 2018 Sep 6.


Sparse Detector Configuration in SiPM Digital Photon Counting PET: a Feasibility Study.

Zhang J, Knopp MI, Knopp MV.

Mol Imaging Biol. 2019 Jun;21(3):447-453. doi: 10.1007/s11307-018-1250-7.


Effect of amorphous phase separation and crystallization on the in vitro and in vivo performance of an amorphous solid dispersion.

Knopp MM, Wendelboe J, Holm R, Rades T.

Eur J Pharm Biopharm. 2018 Sep;130:290-295. doi: 10.1016/j.ejpb.2018.07.005. Epub 2018 Jul 3.


Assessment of chicken breast meat quality after freeze/thaw abuse using magnetic resonance imaging techniques.

Frelka JC, Phinney DM, Yang X, Knopp MV, Heldman DR, Wick MP, Vodovotz Y.

J Sci Food Agric. 2019 Jan 30;99(2):844-853. doi: 10.1002/jsfa.9254. Epub 2018 Aug 29.


Development of an orthotopic canine prostate cancer model expressing human GRPr.

Tweedle MF, Ding H, Drost WT, Dowell J, Spain J, Joseph M, Elshafae SM, Menendez MI, Gong L, Kothandaraman S, Dirksen WP, Wright CL, Bahnson R, Knopp MV, Rosol TJ.

Prostate. 2018 Jul 11. doi: 10.1002/pros.23686. [Epub ahead of print]


How Long of a Dynamic 3'-Deoxy-3'-[18F]fluorothymidine ([18F]FLT) PET Acquisition Is Needed for Robust Kinetic Analysis in Breast Cancer?

Zhang J, Liu X, Knopp MI, Ramaswamy B, Knopp MV.

Mol Imaging Biol. 2019 Apr;21(2):382-390. doi: 10.1007/s11307-018-1231-x.


Development and optimization of a novel automated loop method for production of [11C]nicotine.

Ghosh A, Woolum K, Knopp MV, Kumar K.

Appl Radiat Isot. 2018 Oct;140:76-82. doi: 10.1016/j.apradiso.2018.05.030. Epub 2018 May 30.


No beneficial fitness effects of random peptides.

Knopp M, Andersson DI.

Nat Ecol Evol. 2018 Jul;2(7):1046-1047. doi: 10.1038/s41559-018-0585-4. No abstract available.


A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function.

Jerlström Hultqvist J, Warsi O, Söderholm A, Knopp M, Eckhard U, Vorontsov E, Selmer M, Andersson DI.

Nat Ecol Evol. 2018 Aug;2(8):1321-1330. doi: 10.1038/s41559-018-0568-5. Epub 2018 May 28.


Predictable Phenotypes of Antibiotic Resistance Mutations.

Knopp M, Andersson DI.

mBio. 2018 May 15;9(3). pii: e00770-18. doi: 10.1128/mBio.00770-18.


Genetic Adaptation to Growth Under Laboratory Conditions in Escherichia coli and Salmonella enterica.

Knöppel A, Knopp M, Albrecht LM, Lundin E, Lustig U, Näsvall J, Andersson DI.

Front Microbiol. 2018 Apr 26;9:756. doi: 10.3389/fmicb.2018.00756. eCollection 2018.


Evolution of high-level resistance during low-level antibiotic exposure.

Wistrand-Yuen E, Knopp M, Hjort K, Koskiniemi S, Berg OG, Andersson DI.

Nat Commun. 2018 Apr 23;9(1):1599. doi: 10.1038/s41467-018-04059-1.


A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica.

Hempel NJ, Brede K, Olesen NE, Genina N, Knopp MM, Löbmann K.

Int J Pharm. 2018 Jun 10;544(1):153-157. doi: 10.1016/j.ijpharm.2018.04.035. Epub 2018 Apr 18.


Prospective Tractography-Based Targeting for Improved Safety of Focused Ultrasound Thalamotomy.

Krishna V, Sammartino F, Agrawal P, Changizi BK, Bourekas E, Knopp MV, Rezai A.

Neurosurgery. 2019 Jan 1;84(1):160-168. doi: 10.1093/neuros/nyy020.


Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy.

Edinger M, Knopp MM, Kerdoncuff H, Rantanen J, Rades T, Löbmann K.

Eur J Pharm Sci. 2018 May 30;117:62-67. doi: 10.1016/j.ejps.2018.02.012. Epub 2018 Feb 8.


Comparison of two DSC-based methods to predict drug-polymer solubility.

Rask MB, Knopp MM, Olesen NE, Holm R, Rades T.

Int J Pharm. 2018 Apr 5;540(1-2):98-105. doi: 10.1016/j.ijpharm.2018.02.002. Epub 2018 Feb 6.


Deep Brain Stimulation of Frontal Lobe Networks to Treat Alzheimer's Disease.

Scharre DW, Weichart E, Nielson D, Zhang J, Agrawal P, Sederberg PB, Knopp MV, Rezai AR; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2018;62(2):621-633. doi: 10.3233/JAD-170082.


Abstracts of the 33rd International Austrian Winter Symposium : Zell am See, Austria. 24-27 January 2018.

Binzel K, Adelaja A, Wright CL, Scharre D, Zhang J, Knopp MV, Teoh EJ, Bottomley D, Scarsbrook A, Payne H, Afaq A, Bomanji J, van As N, Chua S, Hoskin P, Chambers A, Cook GJ, Warbey VS, Chau A, Ward P, Miller MP, Stevens DJ, Wilson L, Gleeson FV, Scheidhauer K, Seidl C, Autenrieth M, Bruchertseifer F, Apostolidis C, Kurtz F, Horn T, Pfob C, Schwaiger M, Gschwend J, D'Alessandria C, Morgenstern A, Uprimny C, Kroiss A, Decristoforo C, von Guggenberg E, Nilica B, Horninger W, Virgolini I, Rasul S, Poetsch N, Woehrer A, Preusser M, Mitterhauser M, Wadsak W, Widhalm G, Mischkulnig M, Hacker M, Traub-Weidinger T, Wright CL, Binzel K, Wuthrick EJ, Miller ED, Maniawski P, Zhang J, Knopp MV, Rep S, Hocevar M, Vaupotic J, Zdesar U, Zaletel K, Lezaic L, Mairinger S, Filip T, Sauberer M, Flunkert S, Wanek T, Stanek J, Okamura N, Langer O, Kuntner C, Fornito MC, Balzano R, Di Martino V, Cacciaguerra S, Russo G, Seifert D, Kleinova M, Cepa A, Ralis J, Hanc P, Lebeda O, Mosa M, Vandenberghe S, Mikhaylova E, Borys D, Viswanath V, Stockhoff M, Efthimiou N, Caribe P, Van Holen R, Karp JS, Binzel K, Zhang J, Wright CL, Maniawski P, Knopp MV, Haller PM, Farhan C, Piackova E, Jäger B, Knoll P, Kiss A, Podesser BK, Wojta J, Huber K, Mirzaei S, Traxl A, Komposch K, Glitzner E, Wanek T, Mairinger S, Sibilia M, Langer O, Fornito MC, Russello M, Russo G, Balzano R, Sorko S, Gallowitsch HJ, Kohlfuerst S, Matschnig S, Rieser M, Sorschag M, Lind P, Ležaič L, Rep S, Žibert J, Frelih N, Šuštar S, Binzel K, Adelaja A, Wright CL, Scharre D, Zhang J, Knopp MV, Baum RP, Langbein T, Singh A, Shahinfar M, Schuchardt C, Volk GF, Kulkarni HR, Fornito MC, Cacciaguerra S, Balzano R, Di Martino GV, Russo G, Thomson WH, Kudlacek M, Karik M, Farhan C, Rieger H, Pokieser W, Glaser K, Mirzaei S, Petz V, Tugendsam C, Buchinger W, Schmoll-Hauer B, Schenk IP, Rudolph K, Krebs M, Zettinig G, Zoufal V, Wanek T, Krohn M, Mairinger S, Stanek J, Sauberer M, Filip T, Pahnke J, Langer O, Weitzer F, Pernthaler B, Salamon S, Aigner R, Koranda P, Henzlová L, Kamínek M, Váchalová M, Bachleda P, Summer D, Garousi J, Oroujeni M, Mitran B, Andersson KG, Vorobyeva A, Löfblom JN, Orlova A, Tolmachev V, Decristoforo C, Kaeopookum P, Summer D, Orasch T, Lechner B, Petrik M, Novy Z, Rangger C, Haas H, Decristoforo C.

EJNMMI Res. 2018 Jan 23;8(Suppl 1):5. doi: 10.1186/s13550-017-0354-4. No abstract available.


Quantitative Assessment of Heterogeneity in Bladder Tumor MRI Diffusivity: Can Response be Predicted Prior to Neoadjuvant Chemotherapy?

Nguyen HT, Mortazavi A, Pohar KS, Zynger DL, Wei L, Shah ZK, Jia G, Knopp MV.

Bladder Cancer. 2017 Oct 27;3(4):237-244. doi: 10.3233/BLC-170110.


Advanced Functional Tumor Imaging and Precision Nuclear Medicine Enabled by Digital PET Technologies.

Wright CL, Binzel K, Zhang J, Knopp MV.

Contrast Media Mol Imaging. 2017 May 16;2017:5260305. doi: 10.1155/2017/5260305. eCollection 2017. Review.


Systemic Biodistribution and Intravitreal Pharmacokinetic Properties of Bevacizumab, Ranibizumab, and Aflibercept in a Nonhuman Primate Model.

Christoforidis JB, Briley K, Binzel K, Bhatia P, Wei L, Kumar K, Knopp MV.

Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5636-5645. doi: 10.1167/iovs.17-22431.


Tumor radiomic heterogeneity: Multiparametric functional imaging to characterize variability and predict response following cervical cancer radiation therapy.

Bowen SR, Yuh WTC, Hippe DS, Wu W, Partridge SC, Elias S, Jia G, Huang Z, Sandison GA, Nelson D, Knopp MV, Lo SS, Kinahan PE, Mayr NA.

J Magn Reson Imaging. 2018 May;47(5):1388-1396. doi: 10.1002/jmri.25874. Epub 2017 Oct 16.


Importance of in vitro dissolution conditions for the in vivo predictability of an amorphous solid dispersion containing a pH-sensitive carrier.

Wendelboe J, Knopp MM, Khan F, Chourak N, Rades T, Holm R.

Int J Pharm. 2017 Oct 5;531(1):324-331. doi: 10.1016/j.ijpharm.2017.08.078. Epub 2017 Aug 18.


Feasibility of Na18F PET/CT and MRI for Noninvasive In Vivo Quantification of Knee Pathophysiological Bone Metabolism in a Canine Model of Post-traumatic Osteoarthritis.

Menendez MI, Hettlich B, Wei L, Knopp MV.

Mol Imaging. 2017 Jan-Dec;16:1536012117714575. doi: 10.1177/1536012117714575.


Preclinical Multimodal Molecular Imaging Using 18F-FDG PET/CT and MRI in a Phase I Study of a Knee Osteoarthritis in In Vivo Canine Model.

Menendez MI, Hettlich B, Wei L, Knopp MV.

Mol Imaging. 2017 Jan 1;16:1536012117697443. doi: 10.1177/1536012117697443.


A Phase I clinical trial of the knee to assess the correlation of gagCEST MRI, delayed gadolinium-enhanced MRI of cartilage and T2 mapping.

Wei W, Lambach B, Jia G, Kaeding C, Flanigan D, Knopp MV.

Eur J Radiol. 2017 May;90:220-224. doi: 10.1016/j.ejrad.2017.02.030. Epub 2017 Mar 6.


Online Social Media Practices in Nuclear Medicine and Molecular Imaging: A Concept to Incentivize Creation of Digital and Web-Based Content.

Wright CL, Niederkohr RD, Knopp MU, Knopp MV.

J Nucl Med. 2017 Jun;58(6):12N-14N. No abstract available.


Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Ocular Melanoma as a Tool to Predict Metastatic Potential.

Wei W, Jia G, von Tengg-Kobligk H, Heverhagen JT, Abdel-Rahman M, Wei L, Christoforidis JB, Davidorf F, Knopp MV.

J Comput Assist Tomogr. 2017 Sep/Oct;41(5):823-827. doi: 10.1097/RCT.0000000000000598.


Clinical feasibility of 90Y digital PET/CT for imaging microsphere biodistribution following radioembolization.

Wright CL, Binzel K, Zhang J, Wuthrick EJ, Knopp MV.

Eur J Nucl Med Mol Imaging. 2017 Jul;44(7):1194-1197. doi: 10.1007/s00259-017-3694-4. Epub 2017 Apr 12.


Minimum lesion detectability as a measure of PET system performance.

Adler S, Seidel J, Choyke P, Knopp MV, Binzel K, Zhang J, Barker C, Conant S, Maass-Moreno R.

EJNMMI Phys. 2017 Dec;4(1):13. doi: 10.1186/s40658-017-0179-2. Epub 2017 Mar 4.


A comparison of FLT to FDG PET/CT in the early assessment of chemotherapy response in stages IB-IIIA resectable NSCLC.

Crandall JP, Tahari AK, Juergens RA, Brahmer JR, Rudin CM, Esposito G, Subramaniam DS, Knopp MV, Hall NC, Gajwani P, Leal JP, Lodge MA, O JH, Gabrielson EW, Shankar LK, Wahl RL.

EJNMMI Res. 2017 Dec;7(1):8. doi: 10.1186/s13550-017-0258-3. Epub 2017 Jan 19.


Assessing the effect of football play on knee articular cartilage using delayed gadolinium-enhanced MRI of cartilage (dGEMRIC).

Wei W, Lambach B, Jia G, Flanigan D, Chaudhari AMW, Wei L, Rogers A, Payne J, Siston RA, Knopp MV.

Magn Reson Imaging. 2017 Jun;39:149-156. doi: 10.1016/j.mri.2017.01.008. Epub 2017 Jan 12.


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