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Items: 1 to 50 of 628

1.

Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework.

Jack CR Jr, Therneau TM, Weigand SD, Wiste HJ, Knopman DS, Vemuri P, Lowe VJ, Mielke MM, Roberts RO, Machulda MM, Graff-Radford J, Jones DT, Schwarz CG, Gunter JL, Senjem ML, Rocca WA, Petersen RC.

JAMA Neurol. 2019 Jul 15. doi: 10.1001/jamaneurol.2019.1971. [Epub ahead of print]

PMID:
31305929
2.

Quantity and quality of mental activities and the risk of incident mild cognitive impairment.

Krell-Roesch J, Syrjanen JA, Vassilaki M, Machulda MM, Mielke MM, Knopman DS, Kremers WK, Petersen RC, Geda YE.

Neurology. 2019 Jul 10. pii: 10.1212/WNL.0000000000007897. doi: 10.1212/WNL.0000000000007897. [Epub ahead of print]

PMID:
31292224
3.

Comparison of the Short Test of Mental Status and the Montreal Cognitive Assessment Across the Cognitive Spectrum.

Townley RA, Syrjanen JA, Botha H, Kremers WK, Aakre JA, Fields JA, Machulda MM, Graff-Radford J, Savica R, Jones DT, Knopman DS, Petersen RC, Boeve BF.

Mayo Clin Proc. 2019 Jul 4. pii: S0025-6196(19)30215-0. doi: 10.1016/j.mayocp.2019.01.043. [Epub ahead of print]

PMID:
31280871
4.

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.

Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Heuer HW, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kramer JH, Kremers WK, Kukull WA, Litvan I, Ljubenkov PA, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ; ARTFL/LEFFTDS consortium.

Alzheimers Dement. 2019 Jul 1. pii: S1552-5260(19)30111-6. doi: 10.1016/j.jalz.2019.04.007. [Epub ahead of print]

5.

The Association of Late-Life Diabetes Status and Hyperglycemia With Incident Mild Cognitive Impairment and Dementia: The ARIC Study.

Rawlings AM, Sharrett AR, Albert MS, Coresh J, Windham BG, Power MC, Knopman DS, Walker K, Burgard S, Mosley TH, Gottesman RF, Selvin E.

Diabetes Care. 2019 Jul;42(7):1248-1254. doi: 10.2337/dc19-0120. Epub 2019 May 21.

PMID:
31221696
6.

Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia.

Jack CR Jr, Wiste HJ, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Lowe VJ, Vemuri P, Machulda MM, Schwarz CG, Gunter JL, Senjem ML, Graff-Radford J, Jones DT, Roberts RO, Rocca WA, Petersen RC.

JAMA. 2019 Jun 18;321(23):2316-2325. doi: 10.1001/jama.2019.7437.

PMID:
31211344
7.

White matter hyperintensities: relationship to amyloid and tau burden.

Graff-Radford J, Arenaza-Urquijo EM, Knopman DS, Schwarz CG, Brown RD, Rabinstein AA, Gunter JL, Senjem ML, Przybelski SA, Lesnick T, Ward C, Mielke MM, Lowe VJ, Petersen RC, Kremers WK, Kantarci K, Jack CR, Vemuri P.

Brain. 2019 Jun 14. pii: awz162. doi: 10.1093/brain/awz162. [Epub ahead of print]

PMID:
31199475
8.

Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome.

Tetzloff KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Schwarz CG, Senjem ML, Reid RI, Gunter JL, Spychalla AJ, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.

Brain. 2019 Jun 14. pii: awz157. doi: 10.1093/brain/awz157. [Epub ahead of print]

PMID:
31199471
9.

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures.

Mielke MM, Syrjanen JA, Blennow K, Zetterberg H, Vemuri P, Skoog I, Machulda MM, Kremers WK, Knopman DS, Jack C Jr, Petersen RC, Kern S.

Neurology. 2019 Jun 10. pii: 10.1212/WNL.0000000000007767. doi: 10.1212/WNL.0000000000007767. [Epub ahead of print]

PMID:
31182505
10.

Chronic Systemic Inflammation Is Associated With Symptoms of Late-Life Depression: The ARIC Study.

Sonsin-Diaz N, Gottesman RF, Fracica E, Walston J, Windham BG, Knopman DS, Walker KA.

Am J Geriatr Psychiatry. 2019 May 21. pii: S1064-7481(19)30366-5. doi: 10.1016/j.jagp.2019.05.011. [Epub ahead of print]

PMID:
31182350
11.

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults.

Lowe VJ, Bruinsma TJ, Wiste HJ, Min HK, Weigand SD, Fang P, Senjem ML, Therneau TM, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr.

Neurology. 2019 Jul 2;93(1):e29-e39. doi: 10.1212/WNL.0000000000007728. Epub 2019 May 30.

PMID:
31147421
12.

Neuropsychological subtypes of incident mild cognitive impairment in the Mayo Clinic Study of Aging.

Machulda MM, Lundt ES, Albertson SM, Kremers WK, Mielke MM, Knopman DS, Bondi MW, Petersen RC.

Alzheimers Dement. 2019 May 22. pii: S1552-5260(19)30089-5. doi: 10.1016/j.jalz.2019.03.014. [Epub ahead of print]

PMID:
31128864
13.

Association Between Critical Care Admissions and Cognitive Trajectories in Older Adults.

Schulte PJ, Warner DO, Martin DP, Deljou A, Mielke MM, Knopman DS, Petersen RC, Weingarten TN, Warner MA, Rabinstein AA, Hanson AC, Schroeder DR, Sprung J.

Crit Care Med. 2019 Aug;47(8):1116-1124. doi: 10.1097/CCM.0000000000003829.

PMID:
31107280
14.

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ; ARTFL/LEFFTDS consortium.

Alzheimers Dement. 2019 May 11. pii: S1552-5260(19)30044-5. doi: 10.1016/j.jalz.2019.01.012. [Epub ahead of print]

15.

Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment.

Wu A, Sharrett AR, Gottesman RF, Power MC, Mosley TH Jr, Jack CR Jr, Knopman DS, Windham BG, Gross AL, Coresh J.

JAMA Netw Open. 2019 May 3;2(5):e193359. doi: 10.1001/jamanetworkopen.2019.3359.

16.

Brain atrophy in primary age-related tauopathy is linked to transactive response DNA-binding protein of 43 kDa.

Josephs KA, Murray ME, Tosakulwong N, Weigand SD, Knopman DS, Petersen RC, Jack CR Jr, Whitwell JL, Dickson DW.

Alzheimers Dement. 2019 Jun;15(6):799-806. doi: 10.1016/j.jalz.2019.03.003. Epub 2019 May 2.

PMID:
31056344
17.

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.

Nat Commun. 2019 May 1;10(1):2068. doi: 10.1038/s41467-019-10160-w.

18.

A brief history of "Alzheimer disease": Multiple meanings separated by a common name.

Knopman DS, Petersen RC, Jack CR Jr.

Neurology. 2019 May 28;92(22):1053-1059. doi: 10.1212/WNL.0000000000007583. Epub 2019 Apr 26. Review.

PMID:
31028129
19.

Investigation of white matter PiB uptake as a marker of white matter integrity.

Zeydan B, Schwarz CG, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Kremers WK, Senjem ML, Gunter JL, Min HK, Vemuri P, Knopman DS, Petersen RC, Jack CR Jr, Kantarci OH, Kantarci K.

Ann Clin Transl Neurol. 2019 Mar 3;6(4):678-688. doi: 10.1002/acn3.741. eCollection 2019 Apr.

20.

Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease.

Sintini I, Martin PR, Graff-Radford J, Senjem ML, Schwarz CG, Machulda MM, Spychalla AJ, Drubach DA, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL.

Neuroimage Clin. 2019 Apr 10;23:101823. doi: 10.1016/j.nicl.2019.101823. [Epub ahead of print]

21.

Lowering of Amyloid-Beta by β-Secretase Inhibitors - Some Informative Failures.

Knopman DS.

N Engl J Med. 2019 Apr 11;380(15):1476-1478. doi: 10.1056/NEJMe1903193. No abstract available.

PMID:
30970194
22.

Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging.

Krell-Roesch J, Vassilaki M, Mielke MM, Kremers WK, Lowe VJ, Vemuri P, Machulda MM, Christianson TJ, Syrjanen JA, Stokin GB, Butler LM, Traber M, Jack CR Jr, Knopman DS, Roberts RO, Petersen RC, Geda YE.

Transl Psychiatry. 2019 Mar 28;9(1):123. doi: 10.1038/s41398-019-0456-z.

23.

The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies.

Arenaza-Urquijo EM, Przybelski SA, Lesnick TL, Graff-Radford J, Machulda MM, Knopman DS, Schwarz CG, Lowe VJ, Mielke MM, Petersen RC, Jack CR, Vemuri P.

Brain. 2019 Apr 1;142(4):1134-1147. doi: 10.1093/brain/awz037.

PMID:
30851100
24.

The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals.

Wennberg AM, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Machulda MM, Petrucelli L, Mielke MM, Jack CR Jr, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA.

Neurobiol Aging. 2019 May;77:26-36. doi: 10.1016/j.neurobiolaging.2019.01.008. Epub 2019 Jan 21.

PMID:
30776649
25.

Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life.

Rawlings AM, Sharrett AR, Mosley TH, Wong DF, Knopman DS, Gottesman RF.

J Alzheimers Dis. 2019;68(2):517-521. doi: 10.3233/JAD-180785.

PMID:
30775981
26.

Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study.

Walker KA, Gottesman RF, Wu A, Knopman DS, Gross AL, Mosley TH Jr, Selvin E, Windham BG.

Neurology. 2019 Mar 12;92(11):e1256-e1267. doi: 10.1212/WNL.0000000000007094. Epub 2019 Feb 13.

PMID:
30760633
27.

Entorhinal cortex tau, amyloid-β, cortical thickness and memory performance in non-demented subjects.

Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Albertson SM, Schwarz CG, Petersen RC, Jack CR.

Brain. 2019 Apr 1;142(4):1148-1160. doi: 10.1093/brain/awz025.

PMID:
30759182
28.

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Pottier C, Ren Y, Perkerson RB 3rd, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, Matchett B, Karydas AM, Hsiung GR, Seelaar H, Mol MO, Finger EC, Graff C, Öijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL, Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL 3rd, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C, Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM, Rademakers R.

Acta Neuropathol. 2019 Jun;137(6):879-899. doi: 10.1007/s00401-019-01962-9. Epub 2019 Feb 9.

PMID:
30739198
29.

Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study.

Schneider ALC, Senjem ML, Wu A, Gross A, Knopman DS, Gunter JL, Schwarz CG, Mosley TH, Gottesman RF, Sharrett AR, Jack CR Jr.

Neurology. 2019 Mar 5;92(10):e1051-e1063. doi: 10.1212/WNL.0000000000007042. Epub 2019 Feb 6.

PMID:
30728308
30.

Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy.

Ali F, Martin PR, Botha H, Ahlskog JE, Bower JH, Masumoto JY, Maraganore D, Hassan A, Eggers S, Boeve BF, Knopman DS, Drubach D, Petersen RC, Dunkley ED, van Gerpen J, Uitti R, Whitwell JL, Dickson DW, Josephs KA.

Mov Disord. 2019 Feb 6. doi: 10.1002/mds.27619. [Epub ahead of print]

PMID:
30726566
31.

Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.

Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ.

Brain. 2019 Feb 1;142(2):443-459. doi: 10.1093/brain/awy319.

PMID:
30698757
32.

Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up.

West NA, Windham BG, Knopman DS, Shibata DK, Coker LH, Mosley TH Jr.

Neurology. 2019 Feb 26;92(9):e917-e923. doi: 10.1212/WNL.0000000000006989. Epub 2019 Jan 18.

PMID:
30659141
33.

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]

34.

The influence of β-amyloid on [18F]AV-1451 in semantic variant of primary progressive aphasia.

Whitwell JL, Martin PR, Duffy JR, Clark HM, Machulda MM, Schwarz CG, Weigand SD, Sintini I, Senjem ML, Ertekin-Taner N, Botha H, Utianski RL, Graff-Radford J, Jones DT, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Neurology. 2019 Feb 12;92(7):e710-e722. doi: 10.1212/WNL.0000000000006913. Epub 2019 Jan 11.

PMID:
30635491
35.

Bad news and good news in AD, and how to reconcile them.

Knopman DS.

Nat Rev Neurol. 2019 Feb;15(2):61-62. doi: 10.1038/s41582-018-0131-7. No abstract available.

PMID:
30622292
36.

18 F-AV-1451 uptake differs between dementia with lewy bodies and posterior cortical atrophy.

Nedelska Z, Josephs KA, Graff-Radford J, Przybelski SA, Lesnick TG, Boeve BF, Drubach DA, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL, Kantarci K.

Mov Disord. 2019 Mar;34(3):344-352. doi: 10.1002/mds.27603. Epub 2019 Jan 7.

37.

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains.

Josephs KA, Murray ME, Tosakulwong N, Weigand SD, Serie AM, Perkerson RB, Matchett BJ, Jack CR Jr, Knopman DS, Petersen RC, Parisi JE, Petrucelli L, Baker M, Rademakers R, Whitwell JL, Dickson DW.

Acta Neuropathol. 2019 Feb;137(2):227-238. doi: 10.1007/s00401-018-1951-7. Epub 2019 Jan 2.

PMID:
30604226
38.

Amyloid- and tau-PET imaging in a familial prion kindred.

Jones DT, Townley RA, Graff-Radford J, Botha H, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Boeve BF.

Neurol Genet. 2018 Dec 3;4(6):e290. doi: 10.1212/NXG.0000000000000290. eCollection 2018 Dec.

39.

Cerebral microbleeds: Prevalence and relationship to amyloid burden.

Graff-Radford J, Botha H, Rabinstein AA, Gunter JL, Przybelski SA, Lesnick T, Huston J 3rd, Flemming KD, Preboske GM, Senjem ML, Brown RD Jr, Mielke MM, Roberts RO, Lowe VJ, Knopman DS, Petersen RC, Kremers W, Vemuri P, Jack CR Jr, Kantarci K.

Neurology. 2019 Jan 15;92(3):e253-e262. doi: 10.1212/WNL.0000000000006780. Epub 2018 Dec 19.

PMID:
30568001
40.

Predicting Progression to Mild Cognitive Impairment.

Petersen RC, Lundt ES, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Roberts RO, Lowe VJ, Machulda MM, Kremers WK, Geda YE, Jack CR Jr.

Ann Neurol. 2019 Jan;85(1):155-160. doi: 10.1002/ana.25388. Epub 2019 Jan 7.

PMID:
30521086
41.

Automated detection of imaging features of disproportionately enlarged subarachnoid space hydrocephalus using machine learning methods.

Gunter NB, Schwarz CG, Graff-Radford J, Gunter JL, Jones DT, Graff-Radford NR, Petersen RC, Knopman DS, Jack CR Jr.

Neuroimage Clin. 2019;21:101605. doi: 10.1016/j.nicl.2018.11.015. Epub 2018 Nov 19.

42.

A Comparison of Partial Volume Correction Techniques for Measuring Change in Serial Amyloid PET SUVR.

Schwarz CG, Gunter JL, Lowe VJ, Weigand S, Vemuri P, Senjem ML, Petersen RC, Knopman DS, Jack CR.

J Alzheimers Dis. 2019;67(1):181-195. doi: 10.3233/JAD-180749.

43.

MRI Outperforms [18F]AV-1451 PET as a Longitudinal Biomarker in Progressive Supranuclear Palsy.

Whitwell JL, Tosakulwong N, Schwarz CG, Botha H, Senjem ML, Spychalla AJ, Ahlskog JE, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Mov Disord. 2019 Jan;34(1):105-113. doi: 10.1002/mds.27546. Epub 2018 Nov 23.

44.

Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without Dementia.

Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Machulda MM, Knopman DS, Coloma PM, Schauble B, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC, Roberts RO.

J Am Geriatr Soc. 2018 Dec;66(12):2274-2281. doi: 10.1111/jgs.15577. Epub 2018 Nov 21.

PMID:
30462843
45.

Impaired Lung Function, Lung Disease, and Risk of Incident Dementia.

Lutsey PL, Chen N, Mirabelli MC, Lakshminarayan K, Knopman DS, Vossel KA, Gottesman RF, Mosley TH, Alonso A.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):1385-1396. doi: 10.1164/rccm.201807-1220OC.

PMID:
30433810
46.

Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43.

Wennberg AM, Tosakulwong N, Lesnick TG, Murray ME, Whitwell JL, Liesinger AM, Petrucelli L, Boeve BF, Parisi JE, Knopman DS, Petersen RC, Dickson DW, Josephs KA.

JAMA Neurol. 2018 Nov 1;75(11):1347-1354. doi: 10.1001/jamaneurol.2018.3139.

PMID:
30422173
47.

Association of Cerebrospinal Fluid Neurofilament Light Protein With Risk of Mild Cognitive Impairment Among Individuals Without Cognitive Impairment.

Kern S, Syrjanen JA, Blennow K, Zetterberg H, Skoog I, Waern M, Hagen CE, van Harten AC, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM.

JAMA Neurol. 2018 Nov 12. doi: 10.1001/jamaneurol.2018.3459. [Epub ahead of print]

PMID:
30419087
48.

Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: Assessing cross-modality equivalence of computerized neuropsychological tests.

Stricker NH, Lundt ES, Edwards KK, Machulda MM, Kremers WK, Roberts RO, Knopman DS, Petersen RC, Mielke MM.

Clin Neuropsychol. 2019 Aug;33(6):1102-1126. doi: 10.1080/13854046.2018.1519085. Epub 2018 Nov 10.

PMID:
30417735
49.

The Association of Mid- and Late-Life Systemic Inflammation with Brain Amyloid Deposition: The ARIC-PET Study.

Walker KA, Windham BG, Brown CH, Knopman DS, Jack CR, Mosley TH, Selvin E, Wong DF, Hughes TM, Zhou Y, Gross AL, Gottesman RF.

J Alzheimers Dis. 2018;66(3):1041-1052. doi: 10.3233/JAD-180469.

50.

Early-Phase Randomized Clinical Trials-Expectations vs Hard Reality.

Knopman DS.

JAMA Neurol. 2019 Jan 1;76(1):15-16. doi: 10.1001/jamaneurol.2018.3301. No abstract available.

PMID:
30383106

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