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Impact of Using Alternative Graft Function Endpoints: A Secondary Analysis of a Kidney Transplant Trial.

Fergusson NA, Ramsay T, Chassé M, English SW, Knoll GA.

Transplant Direct. 2019 Mar 19;5(4):e439. doi: 10.1097/TXD.0000000000000880. eCollection 2019 Apr.


Multicentre randomised controlled trial protocol of urine CXCL10 monitoring strategy in kidney transplant recipients.

Ho J, Sharma A, Kroeker K, Carroll R, De Serres S, Gibson IW, Hirt-Minkowski P, Jevnikar A, Kim SJ, Knoll G, Rush DN, Wiebe C, Nickerson P.

BMJ Open. 2019 Apr 11;9(4):e024908. doi: 10.1136/bmjopen-2018-024908.


Clinical outcomes of polyvalent immunoglobulin use in solid organ transplant recipients: A systematic review and meta-analysis.

Bourassa-Blanchette S, Knoll GA, Hutton B, Fergusson N, Bennett A, Tay J, Cameron DW, Cowan J.

Clin Transplant. 2019 Apr 2:e13560. doi: 10.1111/ctr.13560. [Epub ahead of print]


Non-reimbursed costs incurred by living kidney donors: A case study from Ontario, Canada.

Barnieh L, Klarenbach S, Arnold J, Cuerden M, Knoll G, Lok C, Sontrop JM, Miller M, Prasad GVR, Przech S, Garg AX; Donor Nephrectomy Outcomes Research (DONOR) Network.

Transplantation. 2019 Mar 1. doi: 10.1097/TP.0000000000002685. [Epub ahead of print]


Mortality in Incident Maintenance Dialysis Patients Versus Incident Solid Organ Cancer Patients: A Population-Based Cohort.

Naylor KL, Kim SJ, McArthur E, Garg AX, McCallum MK, Knoll GA.

Am J Kidney Dis. 2019 Jan 28. pii: S0272-6386(18)31126-0. doi: 10.1053/j.ajkd.2018.12.011. [Epub ahead of print]


Renal hypothermia during partial nephrectomy for patients with renal tumours: a randomised controlled clinical trial protocol.

Breau RH, Cagiannos I, Knoll G, Morash C, Cnossen S, Lavallée LT, Mallick R, Finelli A, Jewett M, Leibovich BC, Cook J, LeBel L, Kapoor A, Pouliot F, Izawa J, Rendon R, Fergusson DA.

BMJ Open. 2019 Jan 3;9(1):e025662. doi: 10.1136/bmjopen-2018-025662.


Potential organ donor identification and system accountability: expert guidance from a Canadian consensus conference.

Zavalkoff S, Shemie SD, Grimshaw JM, Chassé M, Squires JE, Linklater S, Appleby A, Hartell D, Lalani J, Lotherington K, Knoll G; Potential Organ Donation Identification and System Accountability (PODISA) Conference Participants (Appendix).

Can J Anaesth. 2019 Apr;66(4):432-447. doi: 10.1007/s12630-018-1252-6. Epub 2018 Dec 18.


Comparison of the new and traditional CKD-EPI GFR estimation equations with urinary inulin clearance: A study of equation performance.

White CA, Allen CM, Akbari A, Collier CP, Holland DC, Day AG, Knoll GA.

Clin Chim Acta. 2019 Jan;488:189-195. doi: 10.1016/j.cca.2018.11.019. Epub 2018 Nov 13.


Financial Costs Incurred by Living Kidney Donors: A Prospective Cohort Study.

Przech S, Garg AX, Arnold JB, Barnieh L, Cuerden MS, Dipchand C, Feldman L, Gill JS, Karpinski M, Knoll G, Lok C, Miller M, Monroy M, Nguan C, Prasad GVR, Sarma S, Sontrop JM, Storsley L, Klarenbach S; Donor Nephrectomy Outcomes Research (DONOR) Network.

J Am Soc Nephrol. 2018 Dec;29(12):2847-2857. doi: 10.1681/ASN.2018040398. Epub 2018 Nov 7.


Informative for Decision Making? The Spectrum and Consistency of Outcomes After Living Kidney Donation Reported in Trials and Observational Studies.

Hanson CS, Sautenet B, Craig JC, Chapman JR, Knoll G, Reese PP, Tong A.

Transplantation. 2019 Feb;103(2):284-290. doi: 10.1097/TP.0000000000002489.


Predicting 3-Year Survival in Patients Receiving Maintenance Dialysis: An External Validation of iChoose Kidney in Ontario, Canada.

Tan VS, Garg AX, McArthur E, Patzer RE, Gander J, Roshanov P, Kim SJ, Knoll GA, Yohanna S, McCallum MK, Naylor KL.

Can J Kidney Health Dis. 2018 Oct 4;5:2054358118799693. doi: 10.1177/2054358118799693. eCollection 2018.


Establishing a Core Outcome Measure for Life Participation: a Standardized Outcomes in Nephrology - Kidney Transplantation (SONG-Tx) Consensus Workshop Report.

Ju A, Josephson MA, Butt Z, Jowsey-Gregoire S, Tan J, Taylor Q, Fowler K, Dobbels F, Caskey F, Jha V, Locke J, Knoll G, Ahn C, Hanson CS, Sautenet B, Manera K, Craig JC, Howell M, Rutherford C, Tong A; SONG-Tx Life Participation Workshop Investigators*.

Transplantation. 2018 Oct 8. doi: 10.1097/TP.0000000000002476. [Epub ahead of print]


Socioeconomic Status and Kidney Transplant Outcomes in a Universal Healthcare System: A Population-based Cohort Study.

Naylor KL, Knoll GA, Shariff SZ, McArthur E, Garg AX, Van Walraven C, Austin PC, McCallum MK, Quinn RR, Tan VS, Kim JS.

Transplantation. 2018 Sep 21. doi: 10.1097/TP.0000000000002383. [Epub ahead of print]


Perspectives on Quality of Care in Kidney Transplantation: A Semistructured Interview Study.

Brett KE, Ertel E, Grimshaw J, Knoll GA.

Transplant Direct. 2018 Aug 21;4(9):e383. doi: 10.1097/TXD.0000000000000820. eCollection 2018 Sep.


Incidence Rate of Post-Kidney Transplant Infection: A Retrospective Cohort Study Examining Infection Rates at a Large Canadian Multicenter Tertiary-Care Facility.

Cowan J, Bennett A, Fergusson N, McLean C, Mallick R, Cameron DW, Knoll G.

Can J Kidney Health Dis. 2018 Sep 12;5:2054358118799692. doi: 10.1177/2054358118799692. eCollection 2018.


Is the Kidney Donor Risk Index a Useful Tool in Non-US Patients?

Young A, Knoll GA, McArthur E, Dixon SN, Garg AX, Lok CE, Lam NN, Kim SJ.

Can J Kidney Health Dis. 2018 Jul 27;5:2054358118791148. doi: 10.1177/2054358118791148. eCollection 2018.


Hypertonicity-imposed BCL-XL addiction primes colorectal cancer cells for death.

Heimer S, Knoll G, Steixner C, Calance DN, Trinh DT, Ehrenschwender M.

Cancer Lett. 2018 Oct 28;435:23-31. doi: 10.1016/j.canlet.2018.07.035. Epub 2018 Jul 31.


Barriers and Enablers to Organ Donation After Circulatory Determination of Death: A Qualitative Study Exploring the Beliefs of Frontline Intensive Care Unit Professionals and Organ Donor Coordinators.

Squires JE, Graham N, Coughlin M, Chassé M, Linklater S, Greenough M, Grimshaw JM, Shemie SD, Dhanani S, Knoll GA.

Transplant Direct. 2018 Jun 27;4(7):e368. doi: 10.1097/TXD.0000000000000805. eCollection 2018 Jul.


Case Mix, Patterns of Care, and Inpatient Outcomes Among Ontario Kidney Transplant Centers: A Population-Based Study.

Tsampalieros A, Knoll GA, Dixon S, English S, Manuel D, Van Walraven C, Taljaard M, Fergusson D.

Can J Kidney Health Dis. 2018 Jul 17;5:2054358117730053. doi: 10.1177/2054358117730053. eCollection 2018.


End-Stage Kidney Disease in Patients With Autosomal Dominant Polycystic Kidney Disease: A 12-Year Study Based on the Canadian Organ Replacement Registry.

Budhram B, Akbari A, Brown P, Biyani M, Knoll G, Zimmerman D, Edwards C, McCormick B, Bugeja A, Sood MM.

Can J Kidney Health Dis. 2018 Jun 11;5:2054358118778568. doi: 10.1177/2054358118778568. eCollection 2018.


Individual patient variability with the application of the kidney failure risk equation in advanced chronic kidney disease.

McCudden C, Akbari A, White CA, Biyani M, Hiremath S, Brown PA, Tangri N, Brimble S, Knoll G, Blake PG, Sood MM.

PLoS One. 2018 Jun 12;13(6):e0198456. doi: 10.1371/journal.pone.0198456. eCollection 2018.


Criteria to Identify a Potential Deceased Organ Donor: A Systematic Review.

Squires JE, Coughlin M, Dorrance K, Linklater S, Chassé M, Grimshaw JM, Shemie SD, Dhanani S, Knoll GA.

Crit Care Med. 2018 Aug;46(8):1318-1327. doi: 10.1097/CCM.0000000000003200.


Effectiveness of immunoglobulin prophylaxis in reducing clinical complications of hematopoietic stem cell transplantation: a systematic review and meta-analysis.

Ahn H, Tay J, Shea B, Hutton B, Shorr R, Knoll GA, Cameron DW, Cowan J.

Transfusion. 2018 Oct;58(10):2437-2452. doi: 10.1111/trf.14656. Epub 2018 May 16.


Tranexamic Acid versus Placebo to Prevent Blood Transfusion during Radical Cystectomy for Bladder Cancer (TACT): Study Protocol for a Randomized Controlled Trial.

Breau RH, Lavallée LT, Cnossen S, Witiuk K, Cagiannos I, Momoli F, Bryson G, Kanji S, Morash C, Turgeon A, Zarychanski R, Mallick R, Knoll G, Fergusson DA.

Trials. 2018 May 2;19(1):261. doi: 10.1186/s13063-018-2626-3.


Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors.

Sirtl S, Knoll G, Trinh DT, Lang I, Siegmund D, Gross S, Schuler-Thurner B, Neubert P, Jantsch J, Wajant H, Ehrenschwender M.

Oncogene. 2018 Jul;37(30):4122-4136. doi: 10.1038/s41388-018-0265-5. Epub 2018 Apr 30.


Validation of Living Donor Nephrectomy Codes.

Lam NN, Lentine KL, Klarenbach S, Sood MM, Kuwornu PJ, Naylor KL, Knoll GA, Kim SJ, Young A, Garg AX.

Can J Kidney Health Dis. 2018 Apr 9;5:2054358118760833. doi: 10.1177/2054358118760833. eCollection 2018.


What does patient engagement mean for Canadian National Transplant Research Program Researchers?

Allard J, Ballesteros F, Anthony SJ, Dumez V, Hartell D, Knoll G, Wright L, Fortin MC.

Res Involv Engagem. 2018 Apr 9;4:13. doi: 10.1186/s40900-018-0096-0. eCollection 2018.


Serum BTP concentrations are not affected by hepatic dysfunction.

Chakraborty D, Akbari A, Knoll GA, Flemming JA, Lowe C, Akbari S, White CA.

BMC Nephrol. 2018 Apr 13;19(1):87. doi: 10.1186/s12882-018-0881-x.


Duration of Living Kidney Transplant Donor Evaluations: Findings From 2 Multicenter Cohort Studies.

Habbous S, Arnold J, Begen MA, Boudville N, Cooper M, Dipchand C, Dixon SN, Feldman LS, Goździk D, Karpinski M, Klarenbach S, Knoll GA, Lam NN, Lentine KL, Lok C, McArthur E, McKenzie S, Miller M, Monroy-Cuadros M, Nguan C, Prasad GVR, Przech S, Sarma S, Segev DL, Storsley L, Garg AX; Donor Nephrectomy Outcomes Research (DONOR) Network.

Am J Kidney Dis. 2018 Oct;72(4):483-498. doi: 10.1053/j.ajkd.2018.01.036. Epub 2018 Mar 24.


Quality Metrics in Solid Organ Transplantation: A Systematic Review.

Brett KE, Ritchie LJ, Ertel E, Bennett A, Knoll GA.

Transplantation. 2018 Jul;102(7):e308-e330. doi: 10.1097/TP.0000000000002149.


Preexisting Cancer in Transplant Candidates: Time for a Change in Practice?

Knoll GA, Chadban SJ.

Transplantation. 2018 Jul;102(7):1037-1038. doi: 10.1097/TP.0000000000002177. No abstract available.


Establishing a Core Outcome Measure for Graft Health: A Standardized Outcomes in Nephrology-Kidney Transplantation (SONG-Tx) Consensus Workshop Report.

Tong A, Sautenet B, Poggio ED, Lentine KL, Oberbauer R, Mannon R, Murphy B, Padilla B, Chow KM, Marson L, Chadban S, Craig JC, Ju A, Manera KE, Hanson CS, Josephson MA, Knoll G; SONG-Tx Graft Health Workshop Investigators.

Transplantation. 2018 Aug;102(8):1358-1366. doi: 10.1097/TP.0000000000002125.


Drug discontinuation before contrast procedures and the effect on acute kidney injury and other clinical outcomes: a systematic review protocol.

Hiremath S, Kayibanda JF, Chow BJW, Fergusson D, Knoll GA, Shabana W, Lahey B, McBride O, Davis A, Akbari A.

Syst Rev. 2018 Feb 21;7(1):34. doi: 10.1186/s13643-018-0701-1. Review.


Hypertonicity primes malignant melanoma cells for apoptosis.

Calance DN, Steixner C, Gross S, Schuler-Thurner B, Knoll G, Ehrenschwender M.

Apoptosis. 2018 Apr;23(3-4):201-209. doi: 10.1007/s10495-018-1446-y.


The win ratio approach did not alter study conclusions and may mitigate concerns regarding unequal composite end points in kidney transplant trials.

Fergusson NA, Ramsay T, Chassé M, English SW, Knoll GA.

J Clin Epidemiol. 2018 Jun;98:9-15. doi: 10.1016/j.jclinepi.2018.02.001. Epub 2018 Feb 9.


Trends in Early Hospital Readmission After Kidney Transplantation, 2002 to 2014: A Population-Based Multicenter Cohort Study.

Naylor KL, Knoll GA, Allen B, Li AH, Garg AX, Lam NN, McCallum MK, Kim SJ.

Transplantation. 2018 Apr;102(4):e171-e179. doi: 10.1097/TP.0000000000002036.


Center Variation and the Effect of Center and Provider Characteristics on Clinical Outcomes in Kidney Transplantation: A Systematic Review of the Evidence.

Tsampalieros A, Knoll GA, Fergusson N, Bennett A, Taljaard M, Fergusson D.

Can J Kidney Health Dis. 2017 Oct 19;4:2054358117735523. doi: 10.1177/2054358117735523. eCollection 2017.


Promoting deceased organ and tissue donation registration in family physician waiting rooms (RegisterNow-1 trial): study protocol for a pragmatic, stepped-wedge, cluster randomized controlled registry.

Li AH, Garg AX, Prakash V, Grimshaw JM, Taljaard M, Mitchell J, Matti D, Linklater S, Naylor KL, Dixon S, Faulds C, Bevan R, Getchell L, Knoll G, Kim SJ, Sontrop J, Bjerre LM, Tong A, Presseau J.

Trials. 2017 Dec 21;18(1):610. doi: 10.1186/s13063-017-2333-5.


Familial Consent for Deceased Organ Donation Among Immigrants and Long-term Residents in Ontario, Canada: A Population-Based Retrospective Cohort Study.

Li AH, Al-Jaishi AA, Weir M, Lam NN, Maclean J, Dhanani S, Kim SJ, Knoll G, Garg AX.

Can J Kidney Health Dis. 2017 Oct 20;4:2054358117735564. doi: 10.1177/2054358117735564. eCollection 2017.


Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients.

Lam NN, Garg AX, Knoll GA, Kim SJ, Lentine KL, McArthur E, Naylor KL, Bota SE, Sood MM.

Am J Nephrol. 2017;46(4):343-354. doi: 10.1159/000480304. Epub 2017 Oct 12.


Hyperosmotic stress enhances cytotoxicity of SMAC mimetics.

Bittner S, Knoll G, Ehrenschwender M.

Cell Death Dis. 2017 Aug 3;8(8):e2967. doi: 10.1038/cddis.2017.355.


Evaluation of a Hockey Deceased Organ Donation Awareness Campaign: A Population-Based Cohort Study.

Naylor KL, McKenzie S, Cherry C, McArthur E, Li AH, McCallum MK, Kim SJ, Prakash V, Knoll GA, Garg AX.

Can J Kidney Health Dis. 2017 Jul 5;4:2054358117717252. doi: 10.1177/2054358117717252. eCollection 2017.


Physical frailty and functional status in patients with advanced kidney disease: a protocol for a systematic review.

Brett KE, Bennett A, Ritchie LJ, Knoll GA.

Syst Rev. 2017 Jul 6;6(1):133. doi: 10.1186/s13643-017-0536-1.


Study of Cardiovascular Outcomes in Renal Transplantation: A Prospective, Multicenter Study to Determine the Incidence of Cardiovascular Events in Renal Transplant Recipients in Ontario, Canada.

Ribic CM, Holland D, Howell J, Jevnikar A, Kim SJ, Knoll G, Lee B, Zaltzman J, Gangji AS.

Can J Kidney Health Dis. 2017 Jun 14;4:2054358117713729. doi: 10.1177/2054358117713729. eCollection 2017.


The Risk of Acute Rejection Following Kidney Transplant by 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Status: A Prospective Cohort Study.

Zimmerman D, House AA, Kim SJ, Booth RA, Zhang T, Ramsay T, Knoll G.

Can J Kidney Health Dis. 2017 Apr 10;4:2054358117699822. doi: 10.1177/2054358117699822. eCollection 2017.


Registration for deceased organ and tissue donation among Ontario immigrants: a population-based cross-sectional study.

Li AH, Lam NN, Dhanani S, Weir M, Prakash V, Kim J, Knoll G, Garg AX.

CMAJ Open. 2016 Oct 11;4(4):E551-E561. doi: 10.9778/cmajo.20160024. eCollection 2016 Oct-Dec.


A national survey of screening and management of hypogammaglobulinemia in Canadian transplantation centers.

Bourassa-Blanchette S, Knoll G, Tay J, Bredeson C, Cameron DW, Cowan J.

Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12706. Epub 2017 May 24.


β-Trace Protein Assays: A Comparison Between Nephelometric and ELISA Methodologies.

White CA, Akbari A, Eckfeldt JH, Chakraborty D, McCudden C, Flemming JA, Lowe C, Labrecque P, Parent JL, Fergusson D, Gill JS, Knoll GA.

Am J Kidney Dis. 2017 Jun;69(6):866-868. doi: 10.1053/j.ajkd.2017.02.371. Epub 2017 Apr 12. No abstract available.


Successful Treatment of PD Peritonitis Due to Morganella morganii Resistant to Third-Generation Cephalosporins - A Case Report.

Keskar V, Biyani M, Amin SO, Knoll G.

Perit Dial Int. 2017 Mar-Apr;37(2):241-242. doi: 10.3747/pdi.2016.00268. Review.


Death receptor 3 signaling enhances proliferation of human regulatory T cells.

Bittner S, Knoll G, Ehrenschwender M.

FEBS Lett. 2017 Apr;591(8):1187-1195. doi: 10.1002/1873-3468.12632. Epub 2017 Apr 10.

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