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Items: 1 to 50 of 102

1.

Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression.

Cuomo ASE, Seaton DD, McCarthy DJ, Martinez I, Bonder MJ, Garcia-Bernardo J, Amatya S, Madrigal P, Isaacson A, Buettner F, Knights A, Natarajan KN; HipSci Consortium, Vallier L, Marioni JC, Chhatriwala M, Stegle O.

Nat Commun. 2020 Feb 10;11(1):810. doi: 10.1038/s41467-020-14457-z.

2.

Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system.

Rawji KS, Young AMH, Ghosh T, Michaels NJ, Mirzaei R, Kappen J, Kolehmainen KL, Alaeiilkhchi N, Lozinski B, Mishra MK, Pu A, Tang W, Zein S, Kaushik DK, Keough MB, Plemel JR, Calvert F, Knights AJ, Gaffney DJ, Tetzlaff W, Franklin RJM, Yong VW.

Acta Neuropathol. 2020 Feb 6. doi: 10.1007/s00401-020-02129-7. [Epub ahead of print]

PMID:
32030468
3.

Synthesis and Post-Polymerization Functionalization of Halogen-Substituted Polyphosphinoboranes to Access Alkyne-Functionalized Derivatives.

Arz MI, Knights AW, Manners I.

Macromol Rapid Commun. 2020 Feb;41(4):e1900468. doi: 10.1002/marc.201900468. Epub 2019 Dec 27.

PMID:
31880037
4.

Do differences in developmental mode shape the potential for local adaptation?

Jupe LL, Bilton DT, Knights AM.

Ecology. 2019 Nov 28:e02942. doi: 10.1002/ecy.2942. [Epub ahead of print]

PMID:
31778204
5.

Thulium-doped tellurium oxide waveguide amplifier with 7.6  dB net gain on a silicon nitride chip.

Kiani KM, Frankis HC, Mbonde HM, Mateman R, Leinse A, Knights AP, Bradley JDB.

Opt Lett. 2019 Dec 1;44(23):5788-5791. doi: 10.1364/OL.44.005788.

PMID:
31774780
6.

Photolytic, radical-mediated hydrophosphination: a convenient post-polymerisation modification route to P-di(organosubstituted) polyphosphinoboranes [RR'PBH2] n.

Knights AW, Chitnis SS, Manners I.

Chem Sci. 2019 Jun 6;10(30):7281-7289. doi: 10.1039/c9sc01428d. eCollection 2019 Aug 14.

7.

Protein Arginine Methyltransferase 1 Interacts With PGC1α and Modulates Thermogenic Fat Activation.

Qiao X, Kim DI, Jun H, Ma Y, Knights AJ, Park MJ, Zhu K, Lipinski JH, Liao J, Li Y, Richard S, Weinman SA, Wu J.

Endocrinology. 2019 Dec 1;160(12):2773-2786. doi: 10.1210/en.2019-00504.

PMID:
31555811
8.

Synthetic, structural and reaction chemistry of N-heterocyclic germylene and stannylene compounds featuring N-boryl substituents.

Kristinsdóttir L, Oldroyd NL, Grabiner R, Knights AW, Heilmann A, Protchenko AV, Niu H, Kolychev EL, Campos J, Hicks J, Christensen KE, Aldridge S.

Dalton Trans. 2019 Aug 21;48(31):11951-11960. doi: 10.1039/c9dt02449b. Epub 2019 Jul 18.

PMID:
31318369
9.

Publisher Correction: Molecular and functional variation in iPSC-derived sensory neurons.

Schwartzentruber J, Foskolou S, Kilpinen H, Rodrigues J, Alasoo K, Knights AJ, Patel M, Goncalves A, Ferreira R, Benn CL, Wilbrey A, Bictash M, Impey E, Cao L, Lainez S, Loucif AJ, Whiting PJ; HIPSCI Consortium, Gutteridge A, Gaffney DJ.

Nat Genet. 2019 Jul;51(7):1190. doi: 10.1038/s41588-019-0445-4.

PMID:
31160811
10.

Reverse engineering field-derived vertical distribution profiles to infer larval swimming behaviors.

James MK, Polton JA, Brereton AR, Howell KL, Nimmo-Smith WAM, Knights AM.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11818-11823. doi: 10.1073/pnas.1900238116. Epub 2019 May 23.

11.

Low-loss TeO2-coated Si3N4 waveguides for application in photonic integrated circuits.

Frankis HC, Kiani KM, Bonneville DB, Zhang C, Norris S, Mateman R, Leinse A, Bassim ND, Knights AP, Bradley JDB.

Opt Express. 2019 Apr 29;27(9):12529-12540. doi: 10.1364/OE.27.012529.

PMID:
31052793
12.

Removal of intertidal grazers by human harvesting leads to alteration of species interactions, community structure and resilience to climate change.

Chaverra A, Wieters E, Foggo A, Knights AM.

Mar Environ Res. 2019 Apr;146:57-65. doi: 10.1016/j.marenvres.2019.03.003. Epub 2019 Mar 19.

PMID:
30914147
13.

Characterization of Glucose Transporter 6 in Lipopolysaccharide-Induced Bone Marrow-Derived Macrophage Function.

Caruana BT, Byrne FL, Knights AJ, Quinlan KGR, Hoehn KL.

J Immunol. 2019 Mar 15;202(6):1826-1832. doi: 10.4049/jimmunol.1801063. Epub 2019 Jan 30.

PMID:
30700586
14.

Urban blue: A global analysis of the factors shaping people's perceptions of the marine environment and ecological engineering in harbours.

Strain EMA, Alexander KA, Kienker S, Morris R, Jarvis R, Coleman R, Bollard B, Firth LB, Knights AM, Grabowski JH, Airoldi L, Chan BKK, Chee SY, Cheng Z, Coutinho R, de Menezes RG, Ding M, Dong Y, Fraser CML, Gómez AG, Juanes JA, Mancuso P, Messano LVR, Naval-Xavier LPD, Scyphers S, Steinberg P, Swearer S, Valdor PF, Wong JXY, Yee J, Bishop MJ.

Sci Total Environ. 2019 Mar 25;658:1293-1305. doi: 10.1016/j.scitotenv.2018.12.285. Epub 2018 Dec 20.

PMID:
30677991
15.

Experimental quantification of the free-carrier effect in silicon waveguides at extended wavelengths.

Hagan DE, Nedeljkovic M, Cao W, Thomson DJ, Mashanovich GZ, Knights AP.

Opt Express. 2019 Jan 7;27(1):166-174. doi: 10.1364/OE.27.000166.

PMID:
30645364
16.

High-resolution genetic mapping of putative causal interactions between regions of open chromatin.

Kumasaka N, Knights AJ, Gaffney DJ.

Nat Genet. 2019 Jan;51(1):128-137. doi: 10.1038/s41588-018-0278-6. Epub 2018 Nov 26.

17.

Changes in the biochemical and nutrient composition of seafood due to ocean acidification and warming.

Lemasson AJ, Hall-Spencer JM, Kuri V, Knights AM.

Mar Environ Res. 2019 Jan;143:82-92. doi: 10.1016/j.marenvres.2018.11.006. Epub 2018 Nov 17.

PMID:
30471787
18.

Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules.

Artuz CM, Knights AJ, Funnell APW, Gonda TJ, Ravid K, Pearson RCM, Quinlan KGR, Crossley M.

Biotechnol Rep (Amst). 2018 Oct 2;20:e00285. doi: 10.1016/j.btre.2018.e00285. eCollection 2018 Dec.

19.

Indications of future performance of native and non-native adult oysters under acidification and warming.

Lemasson AJ, Hall-Spencer JM, Fletcher S, Provstgaard-Morys S, Knights AM.

Mar Environ Res. 2018 Nov;142:178-189. doi: 10.1016/j.marenvres.2018.10.003. Epub 2018 Oct 15.

PMID:
30352700
20.

Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules.

Bethune MT, Li XH, Yu J, McLaughlin J, Cheng D, Mathis C, Moreno BH, Woods K, Knights AJ, Garcia-Diaz A, Wong S, Hu-Lieskovan S, Puig-Saus C, Cebon J, Ribas A, Yang L, Witte ON, Baltimore D.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10702-E10711. doi: 10.1073/pnas.1810653115. Epub 2018 Oct 22.

21.

Defining Eosinophil Function in Adiposity and Weight Loss.

Knights AJ, Vohralik EJ, Hoehn KL, Crossley M, Quinlan KGR.

Bioessays. 2018 Oct;40(10):e1800098. doi: 10.1002/bies.201800098. Epub 2018 Aug 22. Review.

PMID:
30132936
22.

Differential phase-shift-keying demodulation by coherent perfect absorption in silicon photonics.

Ahmed A, Yang H, Rothenberg JM, Souhan B, Wang Z, Abrams NC, Meng X, Ingold KA, Evans CC, Hensley JM, Bergman K, Grote RR, Knights AP, Dadap JI, Osgood RM.

Opt Lett. 2018 Aug 15;43(16):4061-4064. doi: 10.1364/OL.43.004061.

PMID:
30106952
23.

The effects of elevated CO2 on shell properties and susceptibility to predation in mussels Mytilus edulis.

Sadler DE, Lemasson AJ, Knights AM.

Mar Environ Res. 2018 Aug;139:162-168. doi: 10.1016/j.marenvres.2018.05.017. Epub 2018 May 21.

PMID:
29803323
24.

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.

Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights AJ, Pardo M, Yu L, Choudhary JS, Metzakopian E, Iyer V, Yun H, Park N, Varela I, Bautista R, Collord G, Dovey O, Garyfallos DA, De Braekeleer E, Kondo S, Cooper J, Göttgens B, Bullinger L, Northcott PA, Adams D, Vassiliou GS, Huntly BJP.

Nat Genet. 2018 Jun;50(6):883-894. doi: 10.1038/s41588-018-0114-z. Epub 2018 May 7.

25.

Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response.

Alasoo K, Rodrigues J, Mukhopadhyay S, Knights AJ, Mann AL, Kundu K; HIPSCI Consortium, Hale C, Dougan G, Gaffney DJ.

Nat Genet. 2018 Mar;50(3):424-431. doi: 10.1038/s41588-018-0046-7. Epub 2018 Jan 29.

26.

Molecular and functional variation in iPSC-derived sensory neurons.

Schwartzentruber J, Foskolou S, Kilpinen H, Rodrigues J, Alasoo K, Knights AJ, Patel M, Goncalves A, Ferreira R, Benn CL, Wilbrey A, Bictash M, Impey E, Cao L, Lainez S, Loucif AJ, Whiting PJ; HIPSCI Consortium, Gutteridge A, Gaffney DJ.

Nat Genet. 2018 Jan;50(1):54-61. doi: 10.1038/s41588-017-0005-8. Epub 2017 Dec 11. Erratum in: Nat Genet. 2019 Jul;51(7):1190.

27.

Resonance control of a silicon micro-ring resonator modulator under high-speed operation using the intrinsic defect-mediated photocurrent.

Wang Z, Paez D, El-Rahman AIA, Wang P, Dow L, Cartledge JC, Knights AP.

Opt Express. 2017 Oct 2;25(20):24827-24836. doi: 10.1364/OE.25.024827.

PMID:
29041295
28.

Experimental demonstration of coherent perfect absorption in a silicon photonic racetrack resonator.

Rothenberg JM, Chen CP, Ackert JJ, Dadap JI, Knights AP, Bergman K, Osgood RM, Grote RR.

Opt Lett. 2016 Jun 1;41(11):2537-40. doi: 10.1364/OL.41.002537.

PMID:
27244408
29.

Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3).

Knights AJ, Yik JJ, Mat Jusoh H, Norton LJ, Funnell AP, Pearson RC, Bell-Anderson KS, Crossley M, Quinlan KG.

J Biol Chem. 2016 Jul 29;291(31):16048-58. doi: 10.1074/jbc.M116.715748. Epub 2016 May 24.

30.

Corrigendum: Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.

Kumasaka N, Knights AJ, Gaffney DJ.

Nat Genet. 2016 Apr;48(4):473. doi: 10.1038/ng0329-473e. No abstract available.

PMID:
27023776
31.

Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma.

Woods K, Knights AJ, Anaka M, Schittenhelm RB, Purcell AW, Behren A, Cebon J.

J Immunother Cancer. 2016 Feb 16;4:10. doi: 10.1186/s40425-016-0111-7. eCollection 2016.

32.

Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.

Kumasaka N, Knights AJ, Gaffney DJ.

Nat Genet. 2016 Feb;48(2):206-13. doi: 10.1038/ng.3467. Epub 2015 Dec 14. Erratum in: Nat Genet. 2016 Apr;48(4):473.

33.

QuantiFERON-TB performance enhanced by novel Mycobacterium tuberculosis-specific antigens.

Losi M, Knights AJ, Mariani F, Altieri AM, Paone G, Loxton AG, Chegou NN, Kenneth J, Alma MG, Colizzi V, Walzl G, Saltini C, Boyle J, Amicosante M.

Eur Respir J. 2016 Feb;47(2):660-4. doi: 10.1183/13993003.01015-2015. Epub 2015 Nov 19. No abstract available.

34.

Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses transcription by interfering with recruitment of RNA PolII by Oct-1.

Bentrari F, Chantôme A, Knights A, Jeannin JF, Pance A.

Nucleic Acids Res. 2015 Nov 16;43(20):9757-65. doi: 10.1093/nar/gkv829. Epub 2015 Aug 13.

35.

Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity.

Dewi V, Kwok A, Lee S, Lee MM, Tan YM, Nicholas HR, Isono K, Wienert B, Mak KS, Knights AJ, Quinlan KG, Cordwell SJ, Funnell AP, Pearson RC, Crossley M.

J Biol Chem. 2015 Mar 27;290(13):8591-605. doi: 10.1074/jbc.M115.638338. Epub 2015 Feb 6.

36.

Silicon-on-insulator sensors using integrated resonance-enhanced defect-mediated photodetectors.

Fard ST, Murray K, Caverley M, Donzella V, Flueckiger J, Grist SM, Huante-Ceron E, Schmidt SA, Kwok E, Jaeger NA, Knights AP, Chrostowski L.

Opt Express. 2014 Nov 17;22(23):28517-29. doi: 10.1364/OE.22.028517.

PMID:
25402094
37.

Optical detection and modulation at 2µm-2.5µm in silicon.

Thomson DJ, Shen L, Ackert JJ, Huante-Ceron E, Knights AP, Nedeljkovic M, Peacock AC, Mashanovich GZ.

Opt Express. 2014 May 5;22(9):10825-30. doi: 10.1364/OE.22.010825.

PMID:
24921782
38.

Monolithic silicon waveguide photodiode utilizing surface-state absorption and operating at 10 Gb/s.

Ackert JJ, Karar AS, Cartledge JC, Jessop PE, Knights AP.

Opt Express. 2014 May 5;22(9):10710-5. doi: 10.1364/OE.22.010710.

PMID:
24921772
39.

MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells.

Vella LJ, Pasam A, Dimopoulos N, Andrews M, Knights A, Puaux AL, Louahed J, Chen W, Woods K, Cebon JS.

Cancer Immunol Res. 2014 Apr;2(4):351-60. doi: 10.1158/2326-6066.CIR-13-0181. Epub 2014 Jan 17.

40.

Adipokines and insulin action: A sensitive issue.

Knights AJ, Funnell AP, Pearson RC, Crossley M, Bell-Anderson KS.

Adipocyte. 2014 Apr 1;3(2):88-96. doi: 10.4161/adip.27552. Epub 2014 Jan 8. Review.

41.

10 Gbps silicon waveguide-integrated infrared avalanche photodiode.

Ackert JJ, Karar AS, Paez DJ, Jessop PE, Cartledge JC, Knights AP.

Opt Express. 2013 Aug 26;21(17):19530-7. doi: 10.1364/OE.21.019530.

PMID:
24105500
42.

Demonstration of a wavelength monitor comprised of racetrack-ring resonators with defect mediated photodiodes operating in the C-band.

Dey R, Doylend J, Ackert J, Evans A, Jessop P, Knights A.

Opt Express. 2013 Oct 7;21(20):23450-8. doi: 10.1364/OE.21.023450.

PMID:
24104259
43.

Predicting free-space occupancy on novel artificial structures by an invasive intertidal barnacle using a removal experiment.

Bracewell SA, Robinson LA, Firth LB, Knights AM.

PLoS One. 2013 Sep 4;8(9):e74457. doi: 10.1371/journal.pone.0074457. eCollection 2013.

44.
45.

Integrated thermal stabilization of a microring modulator.

Padmaraju K, Logan DF, Zhu X, Ackert JJ, Knights AP, Bergman K.

Opt Express. 2013 Jun 17;21(12):14342-50. doi: 10.1364/OE.21.014342.

PMID:
23787622
46.

Atomic-level 2-dimensional chemical mapping and imaging of individual dopants in a phosphor crystal.

Zhu GZ, Lazar S, Knights AP, Botton GA.

Phys Chem Chem Phys. 2013 Jul 21;15(27):11420-6. doi: 10.1039/c3cp51135a. Epub 2013 Jun 7.

PMID:
23744110
47.

Sub-ångstrom experimental validation of molecular dynamics for predictive modeling of extended defect structures in Si.

Dudeck KJ, Marqués LA, Knights AP, Gwilliam RM, Botton GA.

Phys Rev Lett. 2013 Apr 19;110(16):166102. Epub 2013 Apr 18.

PMID:
23679624
48.

Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).

Bell-Anderson KS, Funnell AP, Williams H, Mat Jusoh H, Scully T, Lim WF, Burdach JG, Mak KS, Knights AJ, Hoy AJ, Nicholas HR, Sainsbury A, Turner N, Pearson RC, Crossley M.

Diabetes. 2013 Aug;62(8):2728-37. doi: 10.2337/db12-1745. Epub 2013 Apr 30.

49.

Direct observation of electron capture and reemission by the divacancy via charge transient positron spectroscopy.

Edwardson CJ, Coleman PG, Paez DJ, Doylend JK, Knights AP.

Phys Rev Lett. 2013 Mar 29;110(13):136401. Epub 2013 Mar 25.

PMID:
23581347
50.

A novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen.

Zhao RY, Mifsud NA, Xiao K, Chan KF, Oveissi S, Jackson HM, Dimopoulos N, Guillaume P, Knights AJ, Lowen T, Robson NC, Russell SE, Scotet E, Davis ID, Maraskovsky E, Cebon J, Luescher IF, Chen W.

PLoS One. 2012;7(9):e44707. doi: 10.1371/journal.pone.0044707. Epub 2012 Sep 6.

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