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Prediction of a positive circumferential resection margin at surgery following neoadjuvant chemotherapy for adenocarcinoma of the oesophagus.

Knight WRC, Yip C, Wulaningsih W, Jacques A, Griffin N, Zylstra J, Van Hemelrijck M, Maisey N, Gaya A, Baker CR, Kelly M, Gossage JA, Lagergren J, Landau D, Goh V, Davies AR; Guy's and St Thomas' Oesophago‐Gastric Research Group, Ngan S, Qureshi A, Deere H, Green M, Chang F, Mahadeva U, Gill-Barman B, George S, Dunn J, Zeki S, Meenan J, Hynes O, Tham G, Iezzi C.

BJS Open. 2019 Aug 22;3(6):767-776. doi: 10.1002/bjs5.50211. eCollection 2019 Dec.


The interactions of dopamine and oxidative damage in the striatum of patients with neurodegenerative diseases.

Li H, Yang P, Knight W, Guo Y, Perlmutter JS, Benzinger TLS, Morris JC, Xu J.

J Neurochem. 2020 Jan;152(2):235-251. doi: 10.1111/jnc.14898. Epub 2019 Nov 4.


The ED-SED Study: A Multicenter, Prospective Cohort Study of Practice Patterns and Clinical Outcomes Associated With Emergency Department SEDation for Mechanically Ventilated Patients.

Fuller BM, Roberts BW, Mohr NM, Knight WA 4th, Adeoye O, Pappal RD, Marshall S, Alunday R, Dettmer M, Goyal M, Gibson C, Levine BJ, Gardner-Gray JM, Mosier J, Dargin J, Mackay F, Johnson NJ, Lokhandwala S, Hough CL, Tonna JE, Tsolinas R, Lin F, Qasim ZA, Harvey CE, Bassin B, Stephens RJ, Yan Y, Carpenter CR, Kollef MH, Avidan MS.

Crit Care Med. 2019 Nov;47(11):1539-1548. doi: 10.1097/CCM.0000000000003928.


Responsible Data Governance of Neuroscience Big Data.

Fothergill BT, Knight W, Stahl BC, Ulnicane I.

Front Neuroinform. 2019 Apr 24;13:28. doi: 10.3389/fninf.2019.00028. eCollection 2019.


Regional and global impacts of the 2007 Port-of-Spain Declaration on noncommunicable diseases.

Kirton J, Knight WA, Hospedales CJ, Hippolyte D, Kulik J.

Rev Panam Salud Publica. 2019 Mar 29;42:e194. doi: 10.26633/RPSP.2018.194. eCollection 2018.


Beyond Research Ethics: Dialogues in Neuro-ICT Research.

Stahl BC, Akintoye S, Fothergill BT, Guerrero M, Knight W, Ulnicane I.

Front Hum Neurosci. 2019 Mar 29;13:105. doi: 10.3389/fnhum.2019.00105. eCollection 2019.


LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion.

Chi C, Leonard A, Knight WE, Beussman KM, Zhao Y, Cao Y, Londono P, Aune E, Trembley MA, Small EM, Jeong MY, Walker LA, Xu H, Sniadecki NJ, Taylor MR, Buttrick PM, Song K.

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):556-565. doi: 10.1073/pnas.1808618116. Epub 2018 Dec 24.


Impact of incremental circumferential resection margin distance on overall survival and recurrence in oesophageal adenocarcinoma.

Knight WRC, Zylstra J, Wulaningsih W, Van Hemelrijck M, Landau D, Maisey N, Gaya A, Baker CR, Gossage JA, Largergren J, Davies AR; Guy's and St Thomas' Oesophago‐Gastric Research Group.

BJS Open. 2018 Apr 23;2(4):229-237. doi: 10.1002/bjs5.65. eCollection 2018 Aug.


Patterns of recurrence in oesophageal cancer following oesophagectomy in the era of neoadjuvant chemotherapy.

Knight WRC, Zylstra J, Van Hemelrijck M, Griffin N, Jacques AET, Maisey N, Baker CR, Gossage JA, Largergren J, Davies AR.

BJS Open. 2018 Mar 15;1(6):182-190. doi: 10.1002/bjs5.30. eCollection 2017 Dec.


A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study.

Ridha BH, Crutch S, Cutler D, Frost C, Knight W, Barker S, Epie N, Warrington EK, Kukkastenvehmas R, Douglas J, Rossor MN.

Alzheimers Res Ther. 2018 May 1;10(1):44. doi: 10.1186/s13195-018-0363-1.


Roles of PDE1 in Pathological Cardiac Remodeling and Dysfunction.

Chen S, Knight WE, Yan C.

J Cardiovasc Dev Dis. 2018 Apr 23;5(2). pii: E22. doi: 10.3390/jcdd5020022. Review.


MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.

Rocha AG, Franco A, Krezel AM, Rumsey JM, Alberti JM, Knight WC, Biris N, Zacharioudakis E, Janetka JW, Baloh RH, Kitsis RN, Mochly-Rosen D, Townsend RR, Gavathiotis E, Dorn GW 2nd.

Science. 2018 Apr 20;360(6386):336-341. doi: 10.1126/science.aao1785.


Emergency Neurological Life Support: Traumatic Spine Injury.

Stein DM, Knight WA 4th.

Neurocrit Care. 2017 Sep;27(Suppl 1):170-180. doi: 10.1007/s12028-017-0462-z.


Repacking 'Privacy' for a Networked World.

Crabtree A, Tolmie P, Knight W.

Comput Support Coop Work. 2017;26(4):453-488. doi: 10.1007/s10606-017-9276-y. Epub 2017 May 29.


PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction.

Knight WE, Chen S, Zhang Y, Oikawa M, Wu M, Zhou Q, Miller CL, Cai Y, Mickelsen DM, Moravec C, Small EM, Abe J, Yan C.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E7116-E7125. doi: 10.1073/pnas.1607728113. Epub 2016 Oct 20.


MORNING EMERGENCIES. A guide to wake-up ischemic strokes Morning emergencies.

Bohanske M, Knight W, McMullan J.

JEMS. 2015 Dec;40(12):35-8. No abstract available.


Emergency Neurological Life Support: Traumatic Spine Injury.

Stein DM, Pineda JA, Roddy V, Knight WA 4th.

Neurocrit Care. 2015 Dec;23 Suppl 2:S155-64. doi: 10.1007/s12028-015-0169-y. Review.


Correction: Genetic Ancestry and Asthma and Rhinitis Occurrence in Hispanic Children: Findings from the Southern California Children's Health Study.

Salam MT, Avoundjian T, Knight WM, Gilliland FD.

PLoS One. 2015 Sep 25;10(9):e0139397. doi: 10.1371/journal.pone.0139397. eCollection 2015. No abstract available.


Enoxaparin venous thromboembolism prophylaxis in bariatric surgery: A best evidence topic.

Parker SG, McGlone ER, Knight WR, Sufi P, Khan OA.

Int J Surg. 2015 Nov;23(Pt A):52-6. doi: 10.1016/j.ijsu.2015.09.005. Epub 2015 Sep 21. Review.


Genetic Ancestry and Asthma and Rhinitis Occurrence in Hispanic Children: Findings from the Southern California Children's Health Study.

Salam MT, Avoundjian T, Knight WM, Gilliland FD.

PLoS One. 2015 Aug 11;10(8):e0135384. doi: 10.1371/journal.pone.0135384. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0139397.


Genetic encoding of the post-translational modification 2-hydroxyisobutyryl-lysine.

Knight WA, Cropp TA.

Org Biomol Chem. 2015 Jun 21;13(23):6479-81. doi: 10.1039/c5ob00283d. Epub 2015 May 22.


Electroencephalography findings in patients presenting to the ED for evaluation of seizures.

Kadambi P, Hart KW, Adeoye OM, Lindsell CJ, Knight WA 4th.

Am J Emerg Med. 2015 Jan;33(1):100-3. doi: 10.1016/j.ajem.2014.10.041. Epub 2014 Oct 30.


DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat.

Nistala R, Habibi J, Aroor A, Sowers JR, Hayden MR, Meuth A, Knight W, Hancock T, Klein T, DeMarco VG, Whaley-Connell A.

Obesity (Silver Spring). 2014 Oct;22(10):2172-9. doi: 10.1002/oby.20833. Epub 2014 Jul 4.


A matched comparison of eptifibatide plus rt-PA versus rt-PA alone in acute ischemic stroke.

Adeoye O, Knight WA, Khoury J, Schmit PA, Sucharew H, Broderick JP, Pancioli AM; CLEAR-ER Investigators.

J Stroke Cerebrovasc Dis. 2014 May-Jun;23(5):e313-5. doi: 10.1016/j.jstrokecerebrovasdis.2013.12.012. Epub 2014 Feb 15.


Therapeutic potential of PDE modulation in treating heart disease.

Knight W, Yan C.

Future Med Chem. 2013 Sep;5(14):1607-20. doi: 10.4155/fmc.13.127. Review.


Central losartan attenuates increases in arterial pressure and expression of FosB/ΔFosB along the autonomic axis associated with chronic intermittent hypoxia.

Knight WD, Saxena A, Shell B, Nedungadi TP, Mifflin SW, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2013 Nov 1;305(9):R1051-8. doi: 10.1152/ajpregu.00541.2012. Epub 2013 Sep 11.


Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury.

Oikawa M, Wu M, Lim S, Knight WE, Miller CL, Cai Y, Lu Y, Blaxall BC, Takeishi Y, Abe J, Yan C.

J Mol Cell Cardiol. 2013 Nov;64:11-9. doi: 10.1016/j.yjmcc.2013.08.003. Epub 2013 Aug 27.


The incidence of seizures in patients undergoing therapeutic hypothermia after resuscitation from cardiac arrest.

Knight WA, Hart KW, Adeoye OM, Bonomo JB, Keegan SP, Ficker DM, Szaflarski JP, Privitera MD, Lindsell CJ.

Epilepsy Res. 2013 Oct;106(3):396-402. doi: 10.1016/j.eplepsyres.2013.06.018. Epub 2013 Jul 29.


Combined approach to lysis utilizing eptifibatide and recombinant tissue plasminogen activator in acute ischemic stroke-enhanced regimen stroke trial.

Pancioli AM, Adeoye O, Schmit PA, Khoury J, Levine SR, Tomsick TA, Sucharew H, Brooks CE, Crocco TJ, Gutmann L, Hemmen TM, Kasner SE, Kleindorfer D, Knight WA, Martini S, McKinney JS, Meurer WJ, Meyer BC, Schneider A, Scott PA, Starkman S, Warach S, Broderick JP; CLEAR-ER Investigators.

Stroke. 2013 Sep;44(9):2381-7. doi: 10.1161/STROKEAHA.113.001059. Epub 2013 Jul 25.


Prospective randomized controlled trial: fibrin sealant reduces split skin graft donor-site pain.

Healy C, Greig AV, Murphy AD, Powell C, Pinder RJ, Saour S, Abela C, Knight W, Geh JL.

Plast Reconstr Surg. 2013 Jul;132(1):139e-46e. doi: 10.1097/PRS.0b013e318299c6f4.


Severe traumatic brain injury in adults.

Zammit C, Knight WA.

Emerg Med Pract. 2013 Mar;15(3):1-28. Epub 2013 Feb 20. Review.


A unique case of peripheral myoclonus.

Ross Russell AL, Knight W, Oware A, Fuller GN.

J Neurol Neurosurg Psychiatry. 2013 Jan;84(1):117-8. doi: 10.1136/jnnp-2012-303795. Epub 2012 Nov 26. No abstract available.


Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5.

Silva J, Polesskaya O, Knight W, Zheng JT, Granger M, Lopez T, Ontiveros F, Feng C, Yan C, Kasischke KA, Dewhurst S.

J Neuroinflammation. 2012 Nov 20;9:253. doi: 10.1186/1742-2094-9-253.


Cardiac cyclic nucleotide phosphodiesterases: function, regulation, and therapeutic prospects.

Knight WE, Yan C.

Horm Metab Res. 2012 Sep;44(10):766-75. doi: 10.1055/s-0032-1321870. Epub 2012 Sep 5. Review.


Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration.

Cai Y, Knight WE, Guo S, Li JD, Knight PA, Yan C.

J Pharmacol Exp Ther. 2012 Nov;343(2):479-88. doi: 10.1124/jpet.112.195446. Epub 2012 Aug 22.


Giant papillary muscles masquerading as a left ventricular mass: an incidental intraoperative echocardiographic finding.

Ho D, Elahi M, Zehr K, Knight W.

Eur J Cardiothorac Surg. 2012 Oct;42(4):749. doi: 10.1093/ejcts/ezs311. Epub 2012 Jul 2. No abstract available.


An Essential role for DeltaFosB in the median preoptic nucleus in the sustained hypertensive effects of chronic intermittent hypoxia.

Cunningham JT, Knight WD, Mifflin SW, Nestler EJ.

Hypertension. 2012 Jul;60(1):179-87. doi: 10.1161/HYPERTENSIONAHA.112.193789. Epub 2012 Jun 11.


Enteral vs total parenteral nutrition following major upper gastrointestinal surgery.

Wheble GA, Knight WR, Khan OA.

Int J Surg. 2012;10(4):194-7. doi: 10.1016/j.ijsu.2012.02.015. Epub 2012 Mar 11. Review.


Overweight female rats selectively breed for low aerobic capacity exhibit increased myocardial fibrosis and diastolic dysfunction.

DeMarco VG, Johnson MS, Ma L, Pulakat L, Mugerfeld I, Hayden MR, Garro M, Knight W, Britton SL, Koch LG, Sowers JR.

Am J Physiol Heart Circ Physiol. 2012 Apr 15;302(8):H1667-82. doi: 10.1152/ajpheart.01027.2011. Epub 2012 Feb 17.


Ground emergency medical services requests for helicopter transfer of ST-segment elevation myocardial infarction patients decrease medical contact to balloon times in rural and suburban settings.

McMullan JT, Hinckley W, Bentley J, Davis T, Fermann GJ, Gunderman M, Hart KW, Knight WA, Lindsell CJ, Miller C, Shackleford A, Gibler WB.

Acad Emerg Med. 2012 Feb;19(2):153-60. doi: 10.1111/j.1553-2712.2011.01273.x.


Helicopter scene response for a STEMI patient transported directly to the cardiac catheterization laboratory.

Palmer C, McMullan J, Knight W, Gunderman M, Hinckley W.

Air Med J. 2011 Nov-Dec;30(6):289-92. doi: 10.1016/j.amj.2011.08.005.


CASE 2--2012 intraoperative diagnosis and management of caseous calcification of the mitral annulus.

McKernan NP, Culp WC Jr, Knight WL, Johnston WE, Sniecinski RM, Lazar HL.

J Cardiothorac Vasc Anesth. 2012 Apr;26(2):327-32. doi: 10.1053/j.jvca.2011.07.015. Epub 2011 Sep 15. No abstract available.


Teaching clinically relevant dental anatomy in the dental curriculum: description and assessment of an innovative module.

Obrez A, Briggs C, Buckman J, Goldstein L, Lamb C, Knight WG.

J Dent Educ. 2011 Jun;75(6):797-804.


Chronic intermittent hypoxia increases blood pressure and expression of FosB/DeltaFosB in central autonomic regions.

Knight WD, Little JT, Carreno FR, Toney GM, Mifflin SW, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2011 Jul;301(1):R131-9. doi: 10.1152/ajpregu.00830.2010. Epub 2011 May 4.


Long-term caloric restriction reduces metabolic rate and heart rate under cool and thermoneutral conditions in FBNF1 rats.

Knight WD, Witte MM, Parsons AD, Gierach M, Overton JM.

Mech Ageing Dev. 2011 May;132(5):220-9. doi: 10.1016/j.mad.2011.04.001. Epub 2011 Apr 12.


The Alabama Drug Discovery Alliance: a collaborative partnership to facilitate academic drug discovery.

Everts M, Knight WB, Harris DR, Secrist JA 3rd, Whitley RJ.

Pharm Res. 2011 Jul;28(7):1454-9. doi: 10.1007/s11095-011-0432-7. Epub 2011 Mar 30.


Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series.

McNaughton D, Knight W, Guerreiro R, Ryan N, Lowe J, Poulter M, Nicholl DJ, Hardy J, Revesz T, Lowe J, Rossor M, Collinge J, Mead S.

Neurobiol Aging. 2012 Feb;33(2):426.e13-21. doi: 10.1016/j.neurobiolaging.2010.10.010. Epub 2010 Dec 28.


Combined amylin-leptin treatment lowers blood pressure and adiposity in lean and obese rats.

Seth R, Knight WD, Overton JM.

Int J Obes (Lond). 2011 Sep;35(9):1183-92. doi: 10.1038/ijo.2010.262. Epub 2010 Dec 21.


Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers.

Knight WD, Okello AA, Ryan NS, Turkheimer FE, Rodríguez Martinez de Llano S, Edison P, Douglas J, Fox NC, Brooks DJ, Rossor MN.

Brain. 2011 Jan;134(Pt 1):293-300. doi: 10.1093/brain/awq310. Epub 2010 Nov 16.


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