Knight SC[au] - PubMed

Search results

Items: 1 to 50 of 240

<< First< Prev

Page of 5

Select item 316652831.

Deficient Resident Memory T-Cell and Cd8 T-Cell Response to Commensals in Inflammatory Bowel Disease.

Noble A, Durant L, Hoyles L, McCartney AL, Man R, Segal J, Costello SP, Hendy P, Reddi D, Bouri S, Lim DNF, Pring T, O'Connor MJ, Datt P, Wilson A, Arebi N, Akbar A, Hart AL, Carding SR, Knight SC.

J Crohns Colitis. 2019 Oct 26. pii: jjz175. doi: 10.1093/ecco-jcc/jjz175. [Epub ahead of print]

PMID:: 31665283

Similar articles

Select item 290802632.

Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies.

Knight SC, Tjian R, Doudna JA.

Angew Chem Int Ed Engl. 2018 Apr 9;57(16):4329-4337. doi: 10.1002/anie.201709201. Epub 2018 Feb 28. Review.

PMID:: 29080263

Free PMC Article

Similar articles

Select item 284171123.

Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients.

Condamine T, Dominguez GA, Youn JI, Kossenkov AV, Mony S, Alicea-Torres K, Tcyganov E, Hashimoto A, Nefedova Y, Lin C, Partlova S, Garfall A, Vogl DT, Xu X, Knight SC, Malietzis G, Lee GH, Eruslanov E, Albelda SM, Wang X, Mehta JL, Bewtra M, Rustgi A, Hockstein N, Witt R, Masters G, Nam B, Smirnov D, Sepulveda MA, Gabrilovich DI.

Sci Immunol. 2016 Aug;1(2). pii: aaf8943. doi: 10.1126/sciimmunol.aaf8943. Epub 2016 Aug 5.

PMID:: 28417112

Free PMC Article

Similar articles

Select item 283667604.

Pilot study of immunological factors in non-inflammatory bowel disease enterocutaneous fistulas.

Rahbour G, Warusavitarne J, Hart AL, Tozer PJ, Ullah MR, Thomas GP, Gabe SM, Knight SC, Al-Hassi HO, Vaizey CJ.

Int J Surg. 2017 May;41:127-133. doi: 10.1016/j.ijsu.2017.03.079. Epub 2017 Mar 30.

PMID:: 28366760

Free Article

Similar articles

Select item 276690255.

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.

East-Seletsky A, O'Connell MR, Knight SC, Burstein D, Cate JH, Tjian R, Doudna JA.

Nature. 2016 Oct 13;538(7624):270-273. doi: 10.1038/nature19802. Epub 2016 Sep 26.

PMID:: 27669025

Free PMC Article

Similar articles

Select item 270039896.

Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer.

Landy J, Ronde E, English N, Clark SK, Hart AL, Knight SC, Ciclitira PJ, Al-Hassi HO.

World J Gastroenterol. 2016 Mar 21;22(11):3117-26. doi: 10.3748/wjg.v22.i11.3117. Review.

PMID:: 27003989

Free PMC Article

Similar articles

Select item 269828067.

Dendritic Cell-T-Cell Circuitry in Health and Changes in Inflammatory Bowel Disease and Its Treatment.

Knight SC.

Dig Dis. 2016;34(1-2):51-7. doi: 10.1159/000442926. Epub 2016 Mar 16. Review.

PMID:: 26982806

Free PMC Article

Similar articles

Select item 269606928.

Body composition of the host influences dendritic cell phenotype in patients treated for colorectal cancer.

Malietzis G, Lee GH, Al-Hassi HO, Bernardo D, Blakemore AI, Kennedy RH, Moorghen M, Jenkins JT, Knight SC.

Tumour Biol. 2016 Aug;37(8):11359-64. doi: 10.1007/s13277-016-5009-y. Epub 2016 Mar 10.

PMID:: 26960692

Free Article

Similar articles

Select item 269428719.

Vora R, Bernardo D, Durant L, Reddi D, Hart AL, Fell JM, Al-Hassi HO, Knight SC.

Oncotarget. 2016 Mar 15;7(11):11913-22. doi: 10.18632/oncotarget.7799.

PMID:: 26942871

Free PMC Article

Similar articles

Select item 2686605410.

Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal Colon.

Bernardo D, Durant L, Mann ER, Bassity E, Montalvillo E, Man R, Vora R, Reddi D, Bayiroglu F, Fernández-Salazar L, English NR, Peake ST, Landy J, Lee GH, Malietzis G, Siaw YH, Murugananthan AU, Hendy P, Sánchez-Recio E, Phillips RK, Garrote JA, Scott P, Parkhill J, Paulsen M, Hart AL, Al-Hassi HO, Arranz E, Walker AW, Carding SR, Knight SC.

Cell Mol Gastroenterol Hepatol. 2015 Sep 3;2(1):22-39.e5. eCollection 2016 Jan.

PMID:: 26866054

Free PMC Article

Similar articles

Select item 2685377911.

Identification and molecular characterization of oat peptides implicated on coeliac immune response.

Comino I, Bernardo D, Bancel E, de Lourdes Moreno M, Sánchez B, Barro F, Šuligoj T, Ciclitira PJ, Cebolla Á, Knight SC, Branlard G, Sousa C.

Food Nutr Res. 2016 Feb 5;60:30324. doi: 10.3402/fnr.v60.30324. eCollection 2016.

PMID:: 26853779

Free PMC Article

Similar articles

Select item 2656485512.

Dynamics of CRISPR-Cas9 genome interrogation in living cells.

Knight SC, Xie L, Deng W, Guglielmi B, Witkowsky LB, Bosanac L, Zhang ET, El Beheiry M, Masson JB, Dahan M, Liu Z, Doudna JA, Tjian R.

Science. 2015 Nov 13;350(6262):823-6. doi: 10.1126/science.aac6572.

PMID:: 26564855

Free Article

Similar articles

Select item 2626440913.

Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis.

Landy J, Walker AW, Li JV, Al-Hassi HO, Ronde E, English NR, Mann ER, Bernardo D, McLaughlin SD, Parkhill J, Ciclitira PJ, Clark SK, Knight SC, Hart AL.

Sci Rep. 2015 Aug 12;5:12955. doi: 10.1038/srep12955.

PMID:: 26264409

Free PMC Article

Similar articles

Select item 2617942514.

The prognostic significance and relationship with body composition of CCR7-positive cells in colorectal cancer.

Malietzis G, Lee GH, Bernardo D, Blakemore AI, Knight SC, Moorghen M, Al-Hassi HO, Jenkins JT.

J Surg Oncol. 2015 Jul;112(1):86-92. doi: 10.1002/jso.23959. Epub 2015 Jul 14.

PMID:: 26179425

Free Article

Similar articles

Select item 2602785215.

Prognostic Value of the Tumour-Infiltrating Dendritic Cells in Colorectal Cancer: A Systematic Review.

Malietzis G, Lee GH, Jenkins JT, Bernardo D, Moorghen M, Knight SC, Al-Hassi HO.

Cell Commun Adhes. 2015;22(1):9-14. doi: 10.3109/15419061.2015.1036859. Epub 2015 May 30. Review.

PMID:: 26027852

Free Article

Similar articles

Select item 2591868816.

Human colon-derived soluble factors modulate gut microbiota composition.

Hevia A, Bernardo D, Montalvillo E, Al-Hassi HO, Fernández-Salazar L, Garrote JA, Milani C, Ventura M, Arranz E, Knight SC, Margolles A, Sánchez B.

Front Oncol. 2015 Apr 13;5:86. doi: 10.3389/fonc.2015.00086. eCollection 2015.

PMID:: 25918688

Free PMC Article

Similar articles

Select item 2566730617.

Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells.

Ortiz ML, Kumar V, Martner A, Mony S, Donthireddy L, Condamine T, Seykora J, Knight SC, Malietzis G, Lee GH, Moorghen M, Lenox B, Luetteke N, Celis E, Gabrilovich D.

J Exp Med. 2015 Mar 9;212(3):351-67. doi: 10.1084/jem.20140835. Epub 2015 Feb 9.

PMID:: 25667306

Free PMC Article

Similar articles

Select item 2566619118.

Compartment-specific immunity in the human gut: properties and functions of dendritic cells in the colon versus the ileum.

Mann ER, Bernardo D, English NR, Landy J, Al-Hassi HO, Peake ST, Man R, Elliott TR, Spranger H, Lee GH, Parian A, Brant SR, Lazarev M, Hart AL, Li X, Knight SC.

Gut. 2016 Feb;65(2):256-70. doi: 10.1136/gutjnl-2014-307916. Epub 2015 Feb 9.

PMID:: 25666191

Free PMC Article

Similar articles

Select item 2564328819.

Low Muscularity and Myosteatosis Is Related to the Host Systemic Inflammatory Response in Patients Undergoing Surgery for Colorectal Cancer.

Malietzis G, Johns N, Al-Hassi HO, Knight SC, Kennedy RH, Fearon KC, Aziz O, Jenkins JT.

Ann Surg. 2016 Feb;263(2):320-5. doi: 10.1097/SLA.0000000000001113.

PMID:: 25643288

Free Article

Similar articles

Select item 2539789220.

Human gut dendritic cells drive aberrant gut-specific t-cell responses in ulcerative colitis, characterized by increased IL-4 production and loss of IL-22 and IFNγ.

Mann ER, Bernardo D, Ng SC, Rigby RJ, Al-Hassi HO, Landy J, Peake ST, Spranger H, English NR, Thomas LV, Stagg AJ, Knight SC, Hart AL.

Inflamm Bowel Dis. 2014 Dec;20(12):2299-307. doi: 10.1097/MIB.0000000000000223.

PMID:: 25397892

Similar articles

Select item 2538028521.

Specific activation of dendritic cells enhances clearance of Bacillus anthracis following infection.

Thompson IJ, Mann ER, Stokes MG, English NR, Knight SC, Williamson D.

PLoS One. 2014 Nov 7;9(11):e109720. doi: 10.1371/journal.pone.0109720. eCollection 2014.

PMID:: 25380285

Free PMC Article

Similar articles

Select item 2522265822.

Innate immune factors in the development and maintenance of pouchitis.

Landy J, Al-Hassi HO, Ronde E, English NR, Mann ER, Bernardo D, Ciclitira PJ, Clark SK, Knight SC, Hart AL.

Inflamm Bowel Dis. 2014 Nov;20(11):1942-9. doi: 10.1097/MIB.0000000000000182.

PMID:: 25222658

Similar articles

Select item 2516346923.

The role of CD40 expression in dendritic cells in cancer biology; a systematic review.

Lee GH, Askari A, Malietzis G, Bernardo D, Clark SK, Knight SC, Al-Hassi HO.

Curr Cancer Drug Targets. 2014;14(7):610-20. Review.

PMID:: 25163469

Similar articles

Select item 2478991124.

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis.

Condamine T, Kumar V, Ramachandran IR, Youn JI, Celis E, Finnberg N, El-Deiry WS, Winograd R, Vonderheide RH, English NR, Knight SC, Yagita H, McCaffrey JC, Antonia S, Hockstein N, Witt R, Masters G, Bauer T, Gabrilovich DI.

J Clin Invest. 2014 Jun;124(6):2626-39. doi: 10.1172/JCI74056. Epub 2014 May 1.

PMID:: 24789911

Free PMC Article

Similar articles

Select item 2468972125.

Constitutive gut-homing capacity on circulating myeloid dendritic cells in coeliac disease.

Comino I, Šuligoj T, Al-Hassi HO, Lee GH, Sousa C, Landy J, Ciclitira PJ, Knight SC, Bernardo D.

Rev Esp Enferm Dig. 2014 Jan;106(1):64-5. No abstract available.

PMID:: 24689721

Free Article

Similar articles

Select item 2434737126.

Altered human gut dendritic cell properties in ulcerative colitis are reversed by Lactobacillus plantarum extracellular encrypted peptide STp.

Al-Hassi HO, Mann ER, Sanchez B, English NR, Peake ST, Landy J, Man R, Urdaci M, Hart AL, Fernandez-Salazar L, Lee GH, Garrote JA, Arranz E, Margolles A, Stagg AJ, Knight SC, Bernardo D.

Mol Nutr Food Res. 2014 May;58(5):1132-43. doi: 10.1002/mnfr.201300596. Epub 2013 Dec 18.

PMID:: 24347371

Free Article

Similar articles

Select item 2409441627.

Probiotic modulation of dendritic cell function is influenced by ageing.

You J, Dong H, Mann ER, Knight SC, Yaqoob P.

Immunobiology. 2014 Feb;219(2):138-48. doi: 10.1016/j.imbio.2013.08.012. Epub 2013 Sep 5.

PMID:: 24094416

Free PMC Article

Similar articles

Select item 2397081428.

Dysregulated circulating dendritic cell function in ulcerative colitis is partially restored by probiotic strain Lactobacillus casei Shirota.

Mann ER, You J, Horneffer-van der Sluis V, Bernardo D, Omar Al-Hassi H, Landy J, Peake ST, Thomas LV, Tee CT, Lee GH, Hart AL, Yaqoob P, Knight SC.

Mediators Inflamm. 2013;2013:573576. doi: 10.1155/2013/573576. Epub 2013 Jul 18.

PMID:: 23970814

Free PMC Article

Similar articles

Select item 2360793429.

Lost therapeutic potential of monocyte-derived dendritic cells through lost tissue homing: stable restoration of gut specificity with retinoic acid.

Bernardo D, Mann ER, Al-Hassi HO, English NR, Man R, Lee GH, Ronde E, Landy J, Peake ST, Hart AL, Knight SC.

Clin Exp Immunol. 2013 Oct;174(1):109-19. doi: 10.1111/cei.12118.

PMID:: 23607934

Free PMC Article

Similar articles

Select item 2359483730.

Mechanisms of action of anti-tumor necrosis factor α agents in Crohn's disease.

Peake ST, Bernardo D, Mann ER, Al-Hassi HO, Knight SC, Hart AL.

Inflamm Bowel Dis. 2013 Jun;19(7):1546-55. doi: 10.1097/MIB.0b013e318281333b. Review.

PMID:: 23594837

Similar articles

Select item 2358278131.

Ageing impairs the T cell response to dendritic cells.

You J, Dong H, Mann ER, Knight SC, Yaqoob P.

Immunobiology. 2013 Aug;218(8):1077-84. doi: 10.1016/j.imbio.2013.02.002. Epub 2013 Mar 1.

PMID:: 23582781

Similar articles

Select item 2335267032.

Intestinal dendritic cells: their role in intestinal inflammation, manipulation by the gut microbiota and differences between mice and men.

Mann ER, Landy JD, Bernardo D, Peake ST, Hart AL, Al-Hassi HO, Knight SC.

Immunol Lett. 2013 Feb;150(1-2):30-40. doi: 10.1016/j.imlet.2013.01.007. Epub 2013 Jan 23. Review.

PMID:: 23352670

Similar articles

Select item 2335257633.

Infliximab induces a dysregulated tissue-homing profile on human T-lymphocytes in-vitro: a novel mechanism for paradoxical inflammation?

Peake ST, Bernardo D, Mann ER, Al-Hassi HO, Knight SC, Hart AL.

J Crohns Colitis. 2013 Oct;7(9):765-7. doi: 10.1016/j.crohns.2013.01.001. Epub 2013 Jan 24. No abstract available.

PMID:: 23352576

Similar articles

Select item 2316883834.

A mechanistic role for leptin in human dendritic cell migration: differences between ileum and colon in health and Crohn's disease.

Al-Hassi HO, Bernardo D, Murugananthan AU, Mann ER, English NR, Jones A, Kamm MA, Arebi N, Hart AL, Blakemore AI, Stagg AJ, Knight SC.

Mucosal Immunol. 2013 Jul;6(4):751-61. doi: 10.1038/mi.2012.113. Epub 2012 Nov 21.

PMID:: 23168838

Free PMC Article

Similar articles

Select item 2310265035.

Homing marker expression on circulating dendritic cells correlates with different phenotypes of Crohn's disease.

Peake ST, Bernardo D, Knight SC, Hart AL.

J Crohns Colitis. 2013 Aug;7(7):594-6. doi: 10.1016/j.crohns.2012.10.002. Epub 2012 Oct 24. No abstract available.

PMID:: 23102650

Similar articles

Select item 2303988236.

Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease.

Mann ER, McCarthy NE, Peake ST, Milestone AN, Al-Hassi HO, Bernardo D, Tee CT, Landy J, Pitcher MC, Cochrane SA, Hart AL, Stagg AJ, Knight SC.

Clin Exp Immunol. 2012 Nov;170(2):122-30. doi: 10.1111/j.1365-2249.2012.04649.x.

PMID:: 23039882

Free PMC Article

Similar articles

Select item 2260624937.

Microbiota/host crosstalk biomarkers: regulatory response of human intestinal dendritic cells exposed to Lactobacillus extracellular encrypted peptide.

Bernardo D, Sánchez B, Al-Hassi HO, Mann ER, Urdaci MC, Knight SC, Margolles A.

PLoS One. 2012;7(5):e36262. doi: 10.1371/journal.pone.0036262. Epub 2012 May 14.

PMID:: 22606249

Free PMC Article

Similar articles

Select item 2253930238.

IL-6 promotes immune responses in human ulcerative colitis and induces a skin-homing phenotype in the dendritic cells and Tcells they stimulate.

Bernardo D, Vallejo-Díez S, Mann ER, Al-Hassi HO, Martínez-Abad B, Montalvillo E, Tee CT, Murugananthan AU, Núñez H, Peake ST, Hart AL, Fernández-Salazar L, Garrote JA, Arranz E, Knight SC.

Eur J Immunol. 2012 May;42(5):1337-53. doi: 10.1002/eji.201142327.

PMID:: 22539302

Free Article

Similar articles

Select item 2224874139.

T-cell proliferation and forkhead box P3 expression in human T cells are dependent on T-cell density: physics of a confined space?

Bernardo D, Al-Hassi HO, Mann ER, Tee CT, Murugananthan AU, Peake ST, Hart AL, Knight SC.

Hum Immunol. 2012 Mar;73(3):223-31. doi: 10.1016/j.humimm.2011.12.017. Epub 2012 Jan 3.

PMID:: 22248741

Similar articles

Select item 2210231840.

Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota.

Benjamin JL, Hedin CR, Koutsoumpas A, Ng SC, McCarthy NE, Prescott NJ, Pessoa-Lopes P, Mathew CG, Sanderson J, Hart AL, Kamm MA, Knight SC, Forbes A, Stagg AJ, Lindsay JO, Whelan K.

Inflamm Bowel Dis. 2012 Jun;18(6):1092-100. doi: 10.1002/ibd.21864. Epub 2011 Aug 29.

PMID:: 22102318

Similar articles

Select item 2202118041.

Etiology of pouchitis.

Landy J, Al-Hassi HO, McLaughlin SD, Knight SC, Ciclitira PJ, Nicholls RJ, Clark SK, Hart AL.

Inflamm Bowel Dis. 2012 Jun;18(6):1146-55. doi: 10.1002/ibd.21911. Epub 2011 Oct 21. Review.

PMID:: 22021180

Similar articles

Select item 2198747342.

Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment.

Mann ER, Bernardo D, Al-Hassi HO, English NR, Clark SK, McCarthy NE, Milestone AN, Cochrane SA, Hart AL, Stagg AJ, Knight SC.

Inflamm Bowel Dis. 2012 Jul;18(7):1275-86. doi: 10.1002/ibd.21893. Epub 2011 Oct 10.

PMID:: 21987473

Similar articles

Select item 2191016543.

Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease.

Ng SC, Benjamin JL, McCarthy NE, Hedin CR, Koutsoumpas A, Plamondon S, Price CL, Hart AL, Kamm MA, Forbes A, Knight SC, Lindsay JO, Whelan K, Stagg AJ.

Inflamm Bowel Dis. 2011 Oct;17(10):2027-37. doi: 10.1002/ibd.21590. Epub 2010 Dec 22.

PMID:: 21910165

Similar articles

Select item 2161957944.

Prospective study of immunological factors in non-inflammatory bowel disease enterocutaneous fistulas.

Rahbour G, Hart AL, Al-Hassi HO, Ullah MR, Gabe SM, Knight SC, Warusavitarne J, Vaizey CJ.

BMC Surg. 2011 May 27;11:12. doi: 10.1186/1471-2482-11-12.

PMID:: 21619579

Free PMC Article

Similar articles

Select item 2126291845.

Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease.

Benjamin JL, Hedin CR, Koutsoumpas A, Ng SC, McCarthy NE, Hart AL, Kamm MA, Sanderson JD, Knight SC, Forbes A, Stagg AJ, Whelan K, Lindsay JO.

Gut. 2011 Jul;60(7):923-9. doi: 10.1136/gut.2010.232025. Epub 2011 Jan 24.

PMID:: 21262918

Similar articles

Select item 2084850746.

Homing of immune cells: role in homeostasis and intestinal inflammation.

Hart AL, Ng SC, Mann E, Al-Hassi HO, Bernardo D, Knight SC.

Inflamm Bowel Dis. 2010 Nov;16(11):1969-77. doi: 10.1002/ibd.21304. Review.

PMID:: 20848507

Similar articles

Select item 2067281247.

Mechanistic study of the stereoselective polymerization of D,L-lactide using indium(III) halides.

Pietrangelo A, Knight SC, Gupta AK, Yao LJ, Hillmyer MA, Tolman WB.

J Am Chem Soc. 2010 Aug 25;132(33):11649-57. doi: 10.1021/ja103841h.

PMID:: 20672812

Similar articles

Select item 2062285948.

Lipid accumulation and dendritic cell dysfunction in cancer.

Herber DL, Cao W, Nefedova Y, Novitskiy SV, Nagaraj S, Tyurin VA, Corzo A, Cho HI, Celis E, Lennox B, Knight SC, Padhya T, McCaffrey TV, McCaffrey JC, Antonia S, Fishman M, Ferris RL, Kagan VE, Gabrilovich DI.

Nat Med. 2010 Aug;16(8):880-6. doi: 10.1038/nm.2172. Epub 2010 Jul 11.