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Items: 32


GPCR interaction as a possible way for allosteric control between receptors.

Pin JP, Kniazeff J, Prézeau L, Liu JF, Rondard P.

Mol Cell Endocrinol. 2019 Apr 15;486:89-95. doi: 10.1016/j.mce.2019.02.019. Epub 2019 Mar 5. Review.


Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics.

Møller TC, Hottin J, Clerté C, Zwier JM, Durroux T, Rondard P, Prézeau L, Royer CA, Pin JP, Margeat E, Kniazeff J.

Sci Rep. 2018 Jul 10;8(1):10414. doi: 10.1038/s41598-018-28682-6.


Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers.

Stewart GD, Comps-Agrar L, Nørskov-Lauritsen LB, Pin JP, Kniazeff J.

Neuropharmacology. 2018 Jul 1;136(Pt A):92-101. doi: 10.1016/j.neuropharm.2017.12.042. Epub 2018 Jan 2.


Class C G protein-coupled receptors: reviving old couples with new partners.

Møller TC, Moreno-Delgado D, Pin JP, Kniazeff J.

Biophys Rep. 2017;3(4):57-63. doi: 10.1007/s41048-017-0036-9. Epub 2017 Feb 28.


RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.

Christensen SB, Hone AJ, Roux I, Kniazeff J, Pin JP, Upert G, Servent D, Glowatzki E, McIntosh JM.

Front Cell Neurosci. 2017 Jul 21;11:219. doi: 10.3389/fncel.2017.00219. eCollection 2017.


FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor.

Lecat-Guillet N, Monnier C, Rovira X, Kniazeff J, Lamarque L, Zwier JM, Trinquet E, Pin JP, Rondard P.

Cell Chem Biol. 2017 Mar 16;24(3):360-370. doi: 10.1016/j.chembiol.2017.02.011. Epub 2017 Mar 9.


Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter:sodium symporter.

Billesbølle CB, Krüger MB, Shi L, Quick M, Li Z, Stolzenberg S, Kniazeff J, Gotfryd K, Mortensen JS, Javitch JA, Weinstein H, Loland CJ, Gether U.

J Biol Chem. 2015 Oct 30;290(44):26725-38. doi: 10.1074/jbc.M115.677658. Epub 2015 Sep 11.


Sensing of amino acids in a dopaminergic circuitry promotes rejection of an incomplete diet in Drosophila.

Bjordal M, Arquier N, Kniazeff J, Pin JP, Léopold P.

Cell. 2014 Jan 30;156(3):510-21. doi: 10.1016/j.cell.2013.12.024.


Time-resolved Förster resonance energy transfer-based technologies to investigate G protein-coupled receptor machinery: high-throughput screening assays and future development.

Scholler P, Zwier JM, Trinquet E, Rondard P, Pin JP, Prézeau L, Kniazeff J.

Prog Mol Biol Transl Sci. 2013;113:275-312. doi: 10.1016/B978-0-12-386932-6.00007-7. Review.


[G-protein-coupled receptors dimers and oligomers: for which purpose? The GABA(B) receptor under investigation].

Kniazeff J, Pin JP.

Med Sci (Paris). 2012 Oct;28(10):858-63. doi: 10.1051/medsci/20122810014. Epub 2012 Oct 12. Review. French.


Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.

Geng Y, Xiong D, Mosyak L, Malito DL, Kniazeff J, Chen Y, Burmakina S, Quick M, Bush M, Javitch JA, Pin JP, Fan QR.

Nat Neurosci. 2012 Jun 3;15(7):970-8. doi: 10.1038/nn.3133.


Stability of GABAB receptor oligomers revealed by dual TR-FRET and drug-induced cell surface targeting.

Comps-Agrar L, Kniazeff J, Brock C, Trinquet E, Pin JP.

FASEB J. 2012 Aug;26(8):3430-9. doi: 10.1096/fj.12-203646. Epub 2012 May 21.


The oligomeric state sets GABA(B) receptor signalling efficacy.

Comps-Agrar L, Kniazeff J, Nørskov-Lauritsen L, Maurel D, Gassmann M, Gregor N, Prézeau L, Bettler B, Durroux T, Trinquet E, Pin JP.

EMBO J. 2011 May 6;30(12):2336-49. doi: 10.1038/emboj.2011.143.


Dimers and beyond: The functional puzzles of class C GPCRs.

Kniazeff J, Prézeau L, Rondard P, Pin JP, Goudet C.

Pharmacol Ther. 2011 Apr;130(1):9-25. doi: 10.1016/j.pharmthera.2011.01.006. Epub 2011 Jan 20. Review.


The complexity of their activation mechanism opens new possibilities for the modulation of mGlu and GABAB class C G protein-coupled receptors.

Rondard P, Goudet C, Kniazeff J, Pin JP, Prézeau L.

Neuropharmacology. 2011 Jan;60(1):82-92. doi: 10.1016/j.neuropharm.2010.08.009. Epub 2010 Aug 14. Review.


Functional crosstalk between GPCRs: with or without oligomerization.

Prezeau L, Rives ML, Comps-Agrar L, Maurel D, Kniazeff J, Pin JP.

Curr Opin Pharmacol. 2010 Feb;10(1):6-13. doi: 10.1016/j.coph.2009.10.009. Epub 2009 Dec 3. Review.


G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors.

Pin JP, Comps-Agrar L, Maurel D, Monnier C, Rives ML, Trinquet E, Kniazeff J, Rondard P, Prézeau L.

J Physiol. 2009 Nov 15;587(Pt 22):5337-44. doi: 10.1113/jphysiol.2009.179978. Epub 2009 Sep 1. Review.


The binding sites for cocaine and dopamine in the dopamine transporter overlap.

Beuming T, Kniazeff J, Bergmann ML, Shi L, Gracia L, Raniszewska K, Newman AH, Javitch JA, Weinstein H, Gether U, Loland CJ.

Nat Neurosci. 2008 Jul;11(7):780-9. doi: 10.1038/nn.2146. Epub 2008 Jun 22.


An intracellular interaction network regulates conformational transitions in the dopamine transporter.

Kniazeff J, Shi L, Loland CJ, Javitch JA, Weinstein H, Gether U.

J Biol Chem. 2008 Jun 20;283(25):17691-701. doi: 10.1074/jbc.M800475200. Epub 2008 Apr 21.


Modeling the binding and function of metabotropic glutamate receptors.

Rovira X, Roche D, Serra J, Kniazeff J, Pin JP, Giraldo J.

J Pharmacol Exp Ther. 2008 May;325(2):443-56. doi: 10.1124/jpet.107.133967. Epub 2008 Feb 20.


Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8.

Kniazeff J, Loland CJ, Goldberg N, Quick M, Das S, Sitte HH, Javitch JA, Gether U.

Neuropharmacology. 2005 Nov;49(6):715-23. Epub 2005 Aug 29.


Allosteric functioning of dimeric class C G-protein-coupled receptors.

Pin JP, Kniazeff J, Liu J, Binet V, Goudet C, Rondard P, Prézeau L.

FEBS J. 2005 Jun;272(12):2947-55. Review.


Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.

Goudet C, Kniazeff J, Hlavackova V, Malhaire F, Maurel D, Acher F, Blahos J, Prézeau L, Pin JP.

J Biol Chem. 2005 Jul 1;280(26):24380-5. Epub 2005 Apr 29.


Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.

Hlavackova V, Goudet C, Kniazeff J, Zikova A, Maurel D, Vol C, Trojanova J, Prézeau L, Pin JP, Blahos J.

EMBO J. 2005 Feb 9;24(3):499-509. Epub 2005 Jan 20.


Activation mechanism of the heterodimeric GABA(B) receptor.

Pin JP, Kniazeff J, Binet V, Liu J, Maurel D, Galvez T, Duthey B, Havlickova M, Blahos J, Prézeau L, Rondard P.

Biochem Pharmacol. 2004 Oct 15;68(8):1565-72.


Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

Kniazeff J, Bessis AS, Maurel D, Ansanay H, Prézeau L, Pin JP.

Nat Struct Mol Biol. 2004 Aug;11(8):706-13. Epub 2004 Jul 4.


The activation mechanism of class-C G-protein coupled receptors.

Pin JP, Kniazeff J, Goudet C, Bessis AS, Liu J, Galvez T, Acher F, Rondard P, Prézeau L.

Biol Cell. 2004 Jun;96(5):335-42. Review.


Cell surface detection of membrane protein interaction with homogeneous time-resolved fluorescence resonance energy transfer technology.

Maurel D, Kniazeff J, Mathis G, Trinquet E, Pin JP, Ansanay H.

Anal Biochem. 2004 Jun 15;329(2):253-62.


Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

Kniazeff J, Saintot PP, Goudet C, Liu J, Charnet A, Guillon G, Pin JP.

J Neurosci. 2004 Jan 14;24(2):370-7.


Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.

Goudet C, Gaven F, Kniazeff J, Vol C, Liu J, Cohen-Gonsaud M, Acher F, Prézeau L, Pin JP.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):378-83. Epub 2003 Dec 22.


Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function.

Galvez T, Duthey B, Kniazeff J, Blahos J, Rovelli G, Bettler B, Prézeau L, Pin JP.

EMBO J. 2001 May 1;20(9):2152-9.

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