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Items: 50

1.

Disruption of a -35kb enhancer impairs CTCF binding and MLH1 expression in colorectal cells.

Liu Q, Thoms JA, Nunez AC, Huang Y, Knezevic K, Packham D, Poulos RC, Williams R, Beck D, Hawkins NJ, Ward RL, Wong JWH, Hesson LB, Sloane MA, Pimanda J.

Clin Cancer Res. 2018 Jun 13. pii: clincanres.3678.2017. doi: 10.1158/1078-0432.CCR-17-3678. [Epub ahead of print]

PMID:
29898989
2.

Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes.

Unnikrishnan A, Papaemmanuil E, Beck D, Deshpande NP, Verma A, Kumari A, Woll PS, Richards LA, Knezevic K, Chandrakanthan V, Thoms JAI, Tursky ML, Huang Y, Ali Z, Olivier J, Galbraith S, Kulasekararaj AG, Tobiasson M, Karimi M, Pellagatti A, Wilson SR, Lindeman R, Young B, Ramakrishna R, Arthur C, Stark R, Crispin P, Curnow J, Warburton P, Roncolato F, Boultwood J, Lynch K, Jacobsen SEW, Mufti GJ, Hellstrom-Lindberg E, Wilkins MR, MacKenzie KL, Wong JWH, Campbell PJ, Pimanda JE.

Cell Rep. 2017 Jul 18;20(3):572-585. doi: 10.1016/j.celrep.2017.06.067.

3.

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.

Unnikrishnan A, Guan YF, Huang Y, Beck D, Thoms JA, Peirs S, Knezevic K, Ma S, de Walle IV, de Jong I, Ali Z, Zhong L, Raftery MJ, Taghon T, Larsson J, MacKenzie KL, Van Vlierberghe P, Wong JW, Pimanda JE.

Nucleic Acids Res. 2016 Dec 15;44(22):10644-10661. Epub 2016 Sep 6.

4.

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes.

Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, Roychoudhuri R, Paul F, Klippert J, Hammes A, Willnow T, Göttgens B, Dzierzak E, Zon LI, Lacaud G, Kouskoff V, Pimanda JE.

Blood. 2016 Oct 13;128(15):1928-1939. Epub 2016 Aug 23. Erratum in: Blood. 2017 Nov 16;130(20):2234.

5.

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.

Huang Y, Thoms JA, Tursky ML, Knezevic K, Beck D, Chandrakanthan V, Suryani S, Olivier J, Boulton A, Glaros EN, Thomas SR, Lock RB, MacKenzie KL, Bushweller JH, Wong JW, Pimanda JE.

Leukemia. 2016 Jul;30(7):1552-61. doi: 10.1038/leu.2016.55. Epub 2016 Mar 8.

6.

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

Chandrakanthan V, Yeola A, Kwan JC, Oliver RA, Qiao Q, Kang YC, Zarzour P, Beck D, Boelen L, Unnikrishnan A, Villanueva JE, Nunez AC, Knezevic K, Palu C, Nasrallah R, Carnell M, Macmillan A, Whan R, Yu Y, Hardy P, Grey ST, Gladbach A, Delerue F, Ittner L, Mobbs R, Walkley CR, Purton LE, Ward RL, Wong JW, Hesson LB, Walsh W, Pimanda JE.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):E2306-15. doi: 10.1073/pnas.1518244113. Epub 2016 Apr 4.

7.

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.

Thoms JA, Knezevic K, Liu JJ, Glaros EN, Thai T, Qiao Q, Campbell H, Packham D, Huang Y, Papathanasiou P, Tunningley R, Whittle B, Yeung AW, Chandrakanthan V, Hesson L, Chen V, Wong JW, Purton LE, Ward RL, Thomas SR, Pimanda JE.

Mol Cell Biol. 2016 Mar 31;36(8):1222-36. doi: 10.1128/MCB.01035-15. Print 2016 Apr.

8.

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis.

Nasrallah R, Knezevic K, Thai T, Thomas SR, Göttgens B, Lacaud G, Kouskoff V, Pimanda JE.

Biol Open. 2015 May 15;4(7):819-29. doi: 10.1242/bio.011494.

9.

SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development.

Marks-Bluth J, Khanna A, Chandrakanthan V, Thoms J, Bee T, Eich C, Kang YC, Knezevic K, Qiao Q, Fitch S, Oxburgh L, Ottersbach K, Dzierzak E, de Bruijn MF, Pimanda JE.

Mol Cell Biol. 2015 Jun;35(12):2165-72. doi: 10.1128/MCB.00239-15. Epub 2015 Apr 13.

10.

Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells.

Jing D, Bhadri VA, Beck D, Thoms JA, Yakob NA, Wong JW, Knezevic K, Pimanda JE, Lock RB.

Blood. 2015 Jan 8;125(2):273-83. doi: 10.1182/blood-2014-05-576470. Epub 2014 Oct 21.

11.

Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias.

Tursky ML, Beck D, Thoms JA, Huang Y, Kumari A, Unnikrishnan A, Knezevic K, Evans K, Richards LA, Lee E, Morris J, Goldberg L, Izraeli S, Wong JW, Olivier J, Lock RB, MacKenzie KL, Pimanda JE.

Leukemia. 2015 Apr;29(4):819-27. doi: 10.1038/leu.2014.299. Epub 2014 Oct 13.

PMID:
25306899
12.

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.

Goldberg L, Tijssen MR, Birger Y, Hannah RL, Kinston SJ, Schütte J, Beck D, Knezevic K, Schiby G, Jacob-Hirsch J, Biran A, Kloog Y, Marcucci G, Bloomfield CD, Aplan PD, Pimanda JE, Göttgens B, Izraeli S.

Blood. 2013 Oct 10;122(15):2694-703. doi: 10.1182/blood-2013-01-477133. Epub 2013 Aug 23.

13.

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.

Beck D, Thoms JA, Perera D, Schütte J, Unnikrishnan A, Knezevic K, Kinston SJ, Wilson NK, O'Brien TA, Göttgens B, Wong JW, Pimanda JE.

Blood. 2013 Oct 3;122(14):e12-22. doi: 10.1182/blood-2013-03-490425. Epub 2013 Aug 23.

14.

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.

Diffner E, Beck D, Gudgin E, Thoms JA, Knezevic K, Pridans C, Foster S, Goode D, Lim WK, Boelen L, Metzeler KH, Micklem G, Bohlander SK, Buske C, Burnett A, Ottersbach K, Vassiliou GS, Olivier J, Wong JW, Göttgens B, Huntly BJ, Pimanda JE.

Blood. 2013 Mar 21;121(12):2289-300. doi: 10.1182/blood-2012-07-446120. Epub 2013 Jan 17. Erratum in: Blood. 2014 May 1;123(18):2901.

15.

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia.

Oram SH, Thoms J, Sive JI, Calero-Nieto FJ, Kinston SJ, Schütte J, Knezevic K, Lock RB, Pimanda JE, Göttgens B.

Leukemia. 2013 Jun;27(6):1348-57. doi: 10.1038/leu.2013.2. Epub 2013 Jan 10.

16.

Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.

Pereira LA, Wong MS, Mossman AK, Sourris K, Janes ME, Knezevic K, Hirst CE, Lim SM, Pimanda JE, Stanley EG, Elefanty AG.

Stem Cell Res. 2012 Mar;8(2):165-79. doi: 10.1016/j.scr.2011.09.007. Epub 2011 Oct 8.

17.

A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis.

Knezevic K, Bee T, Wilson NK, Janes ME, Kinston S, Polderdijk S, Kolb-Kokocinski A, Ottersbach K, Pencovich N, Groner Y, de Bruijn M, Göttgens B, Pimanda JE.

Mol Cell Biol. 2011 Jul;31(14):2817-26. doi: 10.1128/MCB.01305-10. Epub 2011 May 16.

18.

ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.

Thoms JA, Birger Y, Foster S, Knezevic K, Kirschenbaum Y, Chandrakanthan V, Jonquieres G, Spensberger D, Wong JW, Oram SH, Kinston SJ, Groner Y, Lock R, MacKenzie KL, Göttgens B, Izraeli S, Pimanda JE.

Blood. 2011 Jun 30;117(26):7079-89. doi: 10.1182/blood-2010-12-317990. Epub 2011 May 2.

19.

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification.

Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson TA, Collin C, Thomas T, Voss AK, Kile BT, Alexander WS, Pimanda JE, Hilton DJ.

Genes Dev. 2011 Feb 1;25(3):251-62. doi: 10.1101/gad.2009211. Epub 2011 Jan 18.

20.

cis-Regulatory remodeling of the SCL locus during vertebrate evolution.

Göttgens B, Ferreira R, Sanchez MJ, Ishibashi S, Li J, Spensberger D, Lefevre P, Ottersbach K, Chapman M, Kinston S, Knezevic K, Hoogenkamp M, Follows GA, Bonifer C, Amaya E, Green AR.

Mol Cell Biol. 2010 Dec;30(24):5741-51. doi: 10.1128/MCB.00870-10. Epub 2010 Oct 18.

21.

Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.

Wilson NK, Foster SD, Wang X, Knezevic K, Schütte J, Kaimakis P, Chilarska PM, Kinston S, Ouwehand WH, Dzierzak E, Pimanda JE, de Bruijn MF, Göttgens B.

Cell Stem Cell. 2010 Oct 8;7(4):532-44. doi: 10.1016/j.stem.2010.07.016.

22.

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors.

Landry JR, Bonadies N, Kinston S, Knezevic K, Wilson NK, Oram SH, Janes M, Piltz S, Hammett M, Carter J, Hamilton T, Donaldson IJ, Lacaud G, Frampton J, Follows G, Kouskoff V, Göttgens B.

Blood. 2009 Jun 4;113(23):5783-92. doi: 10.1182/blood-2008-11-187757. Epub 2009 Jan 26.

23.

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code.

Pimanda JE, Chan WY, Wilson NK, Smith AM, Kinston S, Knezevic K, Janes ME, Landry JR, Kolb-Kokocinski A, Frampton J, Tannahill D, Ottersbach K, Follows GA, Lacaud G, Kouskoff V, Göttgens B.

Blood. 2008 Dec 1;112(12):4512-22. doi: 10.1182/blood-2008-05-157560. Epub 2008 Sep 19.

24.

[On the development of the infectology service in Novi Sad].

Canak G, Vukadinov J, Brkić S, Svarc D, Ruzić M, Kovacević N, Fabri M, Jovanović J, Klasnja B, Cvjetković D, Doder R, Sević S, Turkulov V, Stefan-Mikić S, Knezević K, Aleksić-Dordević M, Preveden T.

Med Pregl. 2007 Nov-Dec;60(11-12):625-8. Serbian.

PMID:
18666608
25.

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.

Landry JR, Kinston S, Knezevic K, de Bruijn MF, Wilson N, Nottingham WT, Peitz M, Edenhofer F, Pimanda JE, Ottersbach K, Göttgens B.

Blood. 2008 Mar 15;111(6):3005-14. doi: 10.1182/blood-2007-07-098830. Epub 2008 Jan 9.

26.

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.

Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WY, Wilson NK, Landry JR, Wood AD, Kolb-Kokocinski A, Green AR, Tannahill D, Lacaud G, Kouskoff V, Göttgens B.

Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17692-7. Epub 2007 Oct 25.

27.

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity.

Pimanda JE, Donaldson IJ, de Bruijn MF, Kinston S, Knezevic K, Huckle L, Piltz S, Landry JR, Green AR, Tannahill D, Göttgens B.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):840-5. Epub 2007 Jan 9.

28.

The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.

Chan WY, Follows GA, Lacaud G, Pimanda JE, Landry JR, Kinston S, Knezevic K, Piltz S, Donaldson IJ, Gambardella L, Sablitzky F, Green AR, Kouskoff V, Göttgens B.

Blood. 2007 Mar 1;109(5):1908-16. Epub 2006 Oct 19.

29.

Fli1, Elf1, and Ets1 regulate the proximal promoter of the LMO2 gene in endothelial cells.

Landry JR, Kinston S, Knezevic K, Donaldson IJ, Green AR, Göttgens B.

Blood. 2005 Oct 15;106(8):2680-7. Epub 2005 Jun 30.

30.

Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development.

Donaldson IJ, Chapman M, Kinston S, Landry JR, Knezevic K, Piltz S, Buckley N, Green AR, Göttgens B.

Hum Mol Genet. 2005 Mar 1;14(5):595-601. Epub 2005 Jan 13.

PMID:
15649946
31.

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells.

Micallef SJ, Janes ME, Knezevic K, Davis RP, Elefanty AG, Stanley EG.

Diabetes. 2005 Feb;54(2):301-5. Epub 2004 Dec 7.

32.

The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.

Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR.

Mol Cell Biol. 2004 Mar;24(5):1870-83.

33.

[Manifestations of visceral and ocular symptoms of toxocariasis in a 6-year-old boy].

Lalosević D, Oros A, Lalosević V, Knezević K, Knezević S, Bozić K, Vlajković K, Gebauer E.

Med Pregl. 2001;54 Suppl 1:51-3. Croatian.

PMID:
12078129
34.

[Salmonella bacteremia].

Preveden T, Knezević K, Brkić S, Jelesić Z.

Med Pregl. 2001 Jul-Aug;54(7-8):367-70. Croatian.

PMID:
11905187
35.

[Neurotrichinosis].

Knezević K, Turkulov V, Canak G, Lalosević V, Tomić S.

Med Pregl. 2001 Sep-Oct;54(9-10):483-5. Croatian.

PMID:
11876013
36.

[Leishmaniasis: case report].

Knezević K, Turkulov V, Celanović M.

Med Pregl. 1998 Nov-Dec;51(11-12):551-3. Croatian.

PMID:
10081279
37.

[Eosinophilia in trichinosis].

Knezević K.

Med Pregl. 1997 May-Jun;50(5-6):207-11. Croatian.

PMID:
9297052
38.

[Clinical characteristics of trichinosis].

Knezević K, Jovanović J.

Med Pregl. 1996;49(11-12):473-7. Croatian.

PMID:
9019631
39.

[Hemorrhagic fever with renal syndrome in Vojvodina].

Jovanović J, Brkić S, Cvjetković D, Mitić I, Knezević K, Madle-Samardzija N, Vukadinov J.

Med Pregl. 1995;48(9-10):336-8. Croatian.

PMID:
8628192
40.

[Therapy of salmonella gastroenterocolitis].

Brkić S, Knezević K, Celanović M, Jovanović J, Madle-Samardzija N.

Med Pregl. 1994;47(9-10):353-7. Croatian.

PMID:
7565327
41.

[Sensorineural impairment in the inner ear in epidemic parotitis].

Madle-Samardzija N, Dimić E, Topolac R, Jovanović J, Knezević K, Celanović M, Canak G, Brkić S.

Med Pregl. 1993;46(9-10):357-60. Croatian.

PMID:
7997214
42.

[Occurrence of Salmonella infection in diarrheal syndromes: the most common types and clinical patterns].

Knezević K, Brkić S, Jovanović J.

Med Pregl. 1993;46(7-8):296-9. Croatian.

PMID:
7968830
43.

[Typhoid fever--case report].

Bogdanović M, Vukadinov J, Celanović M, Knezević K, Canak G, Jovanović J.

Med Pregl. 1992;45(5-6):199-200. Croatian.

PMID:
1365057
44.

[Pneumococcal meningitis from 1974 to 1984].

Vukadinov J, Madle-Samardzija N, Bogdanović M, Jovanović J, Knezević K, Preveden T.

Med Pregl. 1992;45(9-10):341-4. Croatian.

PMID:
1344470
45.

[Abdominal typhus today].

Knezević K, Jovanović J, Celanović M, Bogdanović M, Madle-Samardzija N, Brkić S, Preveden T.

Med Pregl. 1992;45(11-12):437-40. Croatian.

PMID:
1344444
46.

[The role of Epstein-Barr viruses as etiologic agents in the mononucleosis syndrome].

Jovanović J, Knezević K, Brkić S, Madle-Samardzija N, Cvetković D, Vukadinov J, Bogdanović M.

Med Pregl. 1992;45(11-12):402-6. Croatian.

PMID:
1344437
47.

[Mumps infection and disorders of glucose tolerance].

Jovanović J, Dimić E, Knezević K, Madle-Samardzija N, Canak G, Preveden T.

Med Pregl. 1991;44(9-10):382-6. Croatian.

PMID:
1806788
48.

[Clinical characteristics in epidemics caused by Salmonella enteritidis in hospitalized patients].

Klasnja B, Knezević K, Bogavac M, Fabri M, Samardzija N, Dević J, Dordević M, Dojić B.

Med Pregl. 1988;41(5-6):234-6. Croatian. No abstract available.

PMID:
3062342
49.

[Salmonella sepsis caused by Salmonella virchow].

Knezević K, Dević J, Celanović M.

Med Pregl. 1987;40(3-4):125-6. Croatian. No abstract available.

PMID:
3670217
50.

[Generalized form of acquired toxoplasmosis].

Knezević K, Mudrić V.

Med Pregl. 1984;37(7-8):317-8. Croatian. No abstract available.

PMID:
6521689

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