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Items: 1 to 50 of 81

1.

The piranha draft genome provides molecular insight associated to its unique feeding behavior.

Schartl M, Kneitz S, Volkoff H, Adolfi M, Schmidt C, Fischer P, Minx P, Tomlinson C, Meyer A, Warren WC.

Genome Biol Evol. 2019 Jul 8. pii: evz139. doi: 10.1093/gbe/evz139. [Epub ahead of print]

PMID:
31282935
2.

The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes.

Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S.

Cell Rep. 2019 Jun 18;27(12):3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071.

3.

Periodontal treatment prevents arthritis in mice and methotrexate ameliorates periodontal bone loss.

Lübcke PM, Ebbers MNB, Volzke J, Bull J, Kneitz S, Engelmann R, Lang H, Kreikemeyer B, Müller-Hilke B.

Sci Rep. 2019 May 31;9(1):8128. doi: 10.1038/s41598-019-44512-9.

4.

Expression Signatures of Cisplatin- and Trametinib-Treated Early-Stage Medaka Melanomas.

Klotz B, Kneitz S, Lu Y, Boswell W, Postlethwait J, Warren W, Walter RB, Schartl M.

G3 (Bethesda). 2019 Jul 9;9(7):2267-2276. doi: 10.1534/g3.119.400051.

5.

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish.

Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C.

Biol Open. 2019 Jun 5;8(6). pii: bio040683. doi: 10.1242/bio.040683.

6.

A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka.

Herpin A, Schmidt C, Kneitz S, Gobé C, Regensburger M, Le Cam A, Montfort J, Adolfi MC, Lillesaar C, Wilhelm D, Kraeussling M, Mourot B, Porcon B, Pannetier M, Pailhoux E, Ettwiller L, Dolle D, Guiguen Y, Schartl M.

PLoS Biol. 2019 Apr 4;17(4):e3000185. doi: 10.1371/journal.pbio.3000185. eCollection 2019 Apr.

7.

The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system.

Du K, Wuertz S, Adolfi M, Kneitz S, Stöck M, Oliveira M, Nóbrega R, Ormanns J, Kloas W, Feron R, Klopp C, Parrinello H, Journot L, He S, Postlethwait J, Meyer A, Guiguen Y, Schartl M.

Sci Rep. 2019 Mar 28;9(1):5293. doi: 10.1038/s41598-019-41457-x.

8.

Application of the Transcriptional Disease Signature (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish Model.

Lu Y, Boswell W, Boswell M, Klotz B, Kneitz S, Regneri J, Savage M, Mendoza C, Postlethwait J, Warren WC, Schartl M, Walter RB.

Sci Rep. 2019 Jan 24;9(1):530. doi: 10.1038/s41598-018-36656-x.

9.

Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression.

Anelli V, Ordas A, Kneitz S, Sagredo LM, Gourain V, Schartl M, Meijer AH, Mione M.

Front Genet. 2018 Dec 18;9:675. doi: 10.3389/fgene.2018.00675. eCollection 2018.

10.

Gene expression variation and parental allele inheritance in a Xiphophorus interspecies hybridization model.

Lu Y, Boswell M, Boswell W, Kneitz S, Klotz B, Savage M, Salinas R, Marks R, Regneri J, Postlethwait J, Warren WC, Schartl M, Walter R.

PLoS Genet. 2018 Dec 26;14(12):e1007875. doi: 10.1371/journal.pgen.1007875. eCollection 2018 Dec.

11.

Long-term experimental hybridisation results in the evolution of a new sex chromosome in swordtail fish.

Franchini P, Jones JC, Xiong P, Kneitz S, Gompert Z, Warren WC, Walter RB, Meyer A, Schartl M.

Nat Commun. 2018 Dec 3;9(1):5136. doi: 10.1038/s41467-018-07648-2.

12.

Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.

Kruber P, Angay O, Winkler A, Bösl MR, Kneitz S, Heinze KG, Gessler M.

Int J Cancer. 2019 Mar 15;144(6):1391-1400. doi: 10.1002/ijc.31952. Epub 2018 Dec 3.

PMID:
30367465
13.

Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka.

Regneri J, Klotz B, Wilde B, Kottler VA, Hausmann M, Kneitz S, Regensburger M, Maurus K, Götz R, Lu Y, Walter RB, Herpin A, Schartl M.

Pigment Cell Melanoma Res. 2019 Mar;32(2):248-258. doi: 10.1111/pcmr.12729. Epub 2018 Sep 6.

PMID:
30117276
14.

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas.

Kunz M, Löffler-Wirth H, Dannemann M, Willscher E, Doose G, Kelso J, Kottek T, Nickel B, Hopp L, Landsberg J, Hoffmann S, Tüting T, Zigrino P, Mauch C, Utikal J, Ziemer M, Schulze HJ, Hölzel M, Roesch A, Kneitz S, Meierjohann S, Bosserhoff A, Binder H, Schartl M.

Oncogene. 2018 Nov;37(47):6136-6151. doi: 10.1038/s41388-018-0385-y. Epub 2018 Jul 11.

PMID:
29995873
15.

APOBEC3G-Regulated Host Factors Interfere with Measles Virus Replication: Role of REDD1 and Mammalian TORC1 Inhibition.

Tiwarekar V, Wohlfahrt J, Fehrholz M, Scholz CJ, Kneitz S, Schneider-Schaulies J.

J Virol. 2018 Aug 16;92(17). pii: e00835-18. doi: 10.1128/JVI.00835-18. Print 2018 Sep 1.

16.

Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly.

Warren WC, García-Pérez R, Xu S, Lampert KP, Chalopin D, Stöck M, Loewe L, Lu Y, Kuderna L, Minx P, Montague MJ, Tomlinson C, Hillier LW, Murphy DN, Wang J, Wang Z, Garcia CM, Thomas GCW, Volff JN, Farias F, Aken B, Walter RB, Pruitt KD, Marques-Bonet T, Hahn MW, Kneitz S, Lynch M, Schartl M.

Nat Ecol Evol. 2018 Apr;2(4):669-679. doi: 10.1038/s41559-018-0473-y. Epub 2018 Feb 12.

17.

Comparison of Xiphophorus and human melanoma transcriptomes reveals conserved pathway interactions.

Lu Y, Boswell M, Boswell W, Kneitz S, Hausmann M, Klotz B, Regneri J, Savage M, Amores A, Postlethwait J, Warren W, Schartl M, Walter R.

Pigment Cell Melanoma Res. 2018 Jul;31(4):496-508. doi: 10.1111/pcmr.12686. Epub 2018 Jan 29.

18.

Expression signatures of early-stage and advanced medaka melanomas.

Klotz B, Kneitz S, Regensburger M, Hahn L, Dannemann M, Kelso J, Nickel B, Lu Y, Boswell W, Postlethwait J, Warren W, Kunz M, Walter RB, Schartl M.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Jun;208:20-28. doi: 10.1016/j.cbpc.2017.11.005. Epub 2017 Nov 21.

19.

Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion.

Silva-Vilches C, Pletinckx K, Lohnert M, Pavlovic V, Ashour D, John V, Vendelova E, Kneitz S, Zhou J, Chen R, Reinheckel T, Mueller TD, Bodem J, Lutz MB.

PLoS One. 2017 Jul 31;12(7):e0178114. doi: 10.1371/journal.pone.0178114. eCollection 2017.

20.

Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels.

Hupe M, Li MX, Kneitz S, Davydova D, Yokota C, Kele J, Hot B, Stenman JM, Gessler M.

Sci Signal. 2017 Jul 11;10(487). pii: eaag2476. doi: 10.1126/scisignal.aag2476.

PMID:
28698213
21.

The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation.

Maurus K, Hufnagel A, Geiger F, Graf S, Berking C, Heinemann A, Paschen A, Kneitz S, Stigloher C, Geissinger E, Otto C, Bosserhoff A, Schartl M, Meierjohann S.

Oncogene. 2017 Sep 7;36(36):5110-5121. doi: 10.1038/onc.2017.135. Epub 2017 May 8.

PMID:
28481878
22.

Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybrids.

Lu Y, Boswell M, Boswell W, Kneitz S, Hausmann M, Klotz B, Regneri J, Savage M, Amores A, Postlethwait J, Warren W, Schartl M, Walter R.

Mol Carcinog. 2017 Aug;56(8):1935-1944. doi: 10.1002/mc.22651. Epub 2017 Apr 13.

23.

Silencing of CDK2, but not CDK1, separates mitogenic from anti-apoptotic signaling, sensitizing p53 defective cells for synthetic lethality.

Nekova TS, Kneitz S, Einsele H, Bargou R, Stuhler G.

Cell Cycle. 2016 Dec;15(23):3203-3209. Epub 2016 Nov 10.

24.

Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1).

Endres M, Kneitz S, Orth MF, Perera RK, Zernecke A, Butt E.

Oncotarget. 2016 Sep 27;7(39):64244-64259. doi: 10.18632/oncotarget.11720.

25.

Germ cell and tumor associated piRNAs in the medaka and Xiphophorus melanoma models.

Kneitz S, Mishra RR, Chalopin D, Postlethwait J, Warren WC, Walter RB, Schartl M.

BMC Genomics. 2016 May 17;17:357. doi: 10.1186/s12864-016-2697-z.

26.

Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy.

Simon CM, Rauskolb S, Gunnersen JM, Holtmann B, Drepper C, Dombert B, Braga M, Wiese S, Jablonka S, Pühringer D, Zielasek J, Hoeflich A, Silani V, Wolf E, Kneitz S, Sommer C, Toyka KV, Sendtner M.

Acta Neuropathol. 2015 Sep;130(3):373-87. doi: 10.1007/s00401-015-1446-8. Epub 2015 May 30.

27.

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells.

Leikam C, Hufnagel AL, Otto C, Murphy DJ, Mühling B, Kneitz S, Nanda I, Schmid M, Wagner TU, Haferkamp S, Bröcker EB, Schartl M, Meierjohann S.

Cell Death Dis. 2015 Apr 2;6:e1711. doi: 10.1038/cddis.2015.71.

28.

Transcriptomics of two evolutionary novelties: how to make a sperm-transfer organ out of an anal fin and a sexually selected "sword" out of a caudal fin.

Kang JH, Manousaki T, Franchini P, Kneitz S, Schartl M, Meyer A.

Ecol Evol. 2015 Feb;5(4):848-64. doi: 10.1002/ece3.1390. Epub 2015 Jan 23.

29.

Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.

Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, Ziegler B, Bausenwein S, Nourkami N, Ludwig N, Keller A, Grimm C, Kneitz S, Williams RD, Chagtai T, Pritchard-Jones K, van Sluis P, Volckmann R, Koster J, Versteeg R, Acha T, O'Sullivan MJ, Bode PK, Niggli F, Tytgat GA, van Tinteren H, van den Heuvel-Eibrink MM, Meese E, Vokuhl C, Leuschner I, Graf N, Eils R, Pfister SM, Kool M, Gessler M.

Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002.

30.

Mechanisms of epigenetic and cell-type specific regulation of Hey target genes in ES cells and cardiomyocytes.

Weber D, Heisig J, Kneitz S, Wolf E, Eilers M, Gessler M.

J Mol Cell Cardiol. 2015 Feb;79:79-88. doi: 10.1016/j.yjmcc.2014.11.004. Epub 2014 Nov 13.

PMID:
25446183
31.

Impact of miR-21, miR-126 and miR-221 as prognostic factors of clear cell renal cell carcinoma with tumor thrombus of the inferior vena cava.

Vergho DC, Kneitz S, Kalogirou C, Burger M, Krebs M, Rosenwald A, Spahn M, Löser A, Kocot A, Riedmiller H, Kneitz B.

PLoS One. 2014 Oct 3;9(10):e109877. doi: 10.1371/journal.pone.0109877. eCollection 2014.

32.

Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation.

Saal L, Briese M, Kneitz S, Glinka M, Sendtner M.

RNA. 2014 Nov;20(11):1789-802. doi: 10.1261/rna.047373.114. Epub 2014 Sep 22.

33.

Gene expression profiles of human dendritic cells interacting with Aspergillus fumigatus in a bilayer model of the alveolar epithelium/endothelium interface.

Morton CO, Fliesser M, Dittrich M, Mueller T, Bauer R, Kneitz S, Hope W, Rogers TR, Einsele H, Loeffler J.

PLoS One. 2014 May 28;9(5):e98279. doi: 10.1371/journal.pone.0098279. eCollection 2014.

34.

Silencing of Dicer1 temporally separates pro- and anti-apoptotic signaling and confers susceptibility to chemotherapy in p53 mutated cells.

Nekova TS, Kneitz S, Einsele H, Stuhler G.

Cell Cycle. 2014;13(14):2192-8. doi: 10.4161/cc.29216. Epub 2014 May 20.

35.

Survival in patients with high-risk prostate cancer is predicted by miR-221, which regulates proliferation, apoptosis, and invasion of prostate cancer cells by inhibiting IRF2 and SOCS3.

Kneitz B, Krebs M, Kalogirou C, Schubert M, Joniau S, van Poppel H, Lerut E, Kneitz S, Scholz CJ, Ströbel P, Gessler M, Riedmiller H, Spahn M.

Cancer Res. 2014 May 1;74(9):2591-603. doi: 10.1158/0008-5472.CAN-13-1606. Epub 2014 Mar 7.

36.

Comparative analysis of melanoma deregulated miRNAs in the medaka and Xiphophorus pigment cell cancer models.

Mishra RR, Kneitz S, Schartl M.

Comp Biochem Physiol C Toxicol Pharmacol. 2014 Jun;163:64-76. doi: 10.1016/j.cbpc.2014.01.002. Epub 2014 Jan 22.

PMID:
24462553
37.

Combination of expression levels of miR-21 and miR-126 is associated with cancer-specific survival in clear-cell renal cell carcinoma.

Vergho D, Kneitz S, Rosenwald A, Scherer C, Spahn M, Burger M, Riedmiller H, Kneitz B.

BMC Cancer. 2014 Jan 15;14:25. doi: 10.1186/1471-2407-14-25.

38.

Anti-Apoptotic Signature in Thymic Squamous Cell Carcinomas - Functional Relevance of Anti-Apoptotic BIRC3 Expression in the Thymic Carcinoma Cell Line 1889c.

Huang B, Belharazem D, Li L, Kneitz S, Schnabel PA, Rieker RJ, Körner D, Nix W, Schalke B, Müller-Hermelink HK, Ott G, Rosenwald A, Ströbel P, Marx A.

Front Oncol. 2013 Dec 31;3:316. doi: 10.3389/fonc.2013.00316. eCollection 2013.

39.

MiR-205 is progressively down-regulated in lymph node metastasis but fails as a prognostic biomarker in high-risk prostate cancer.

Kalogirou C, Spahn M, Krebs M, Joniau S, Lerut E, Burger M, Scholz CJ, Kneitz S, Riedmiller H, Kneitz B.

Int J Mol Sci. 2013 Oct 29;14(11):21414-34. doi: 10.3390/ijms141121414.

40.

Distinct microRNA expression profile in prostate cancer patients with early clinical failure and the impact of let-7 as prognostic marker in high-risk prostate cancer.

Schubert M, Spahn M, Kneitz S, Scholz CJ, Joniau S, Stroebel P, Riedmiller H, Kneitz B.

PLoS One. 2013 Jun 14;8(6):e65064. doi: 10.1371/journal.pone.0065064. Print 2013.

41.

How do stomata sense reductions in atmospheric relative humidity?

Bauer H, Ache P, Wohlfart F, Al-Rasheid KA, Sonnewald S, Sonnewald U, Kneitz S, Hetherington AM, Hedrich R.

Mol Plant. 2013 Sep;6(5):1703-6. doi: 10.1093/mp/sst055. Epub 2013 Mar 27. No abstract available.

42.

DNA methylation mediated control of gene expression is critical for development of crown gall tumors.

Gohlke J, Scholz CJ, Kneitz S, Weber D, Fuchs J, Hedrich R, Deeken R.

PLoS Genet. 2013;9(2):e1003267. doi: 10.1371/journal.pgen.1003267. Epub 2013 Feb 7.

43.

Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells.

Riedel A, Mofolo B, Avota E, Schneider-Schaulies S, Meintjes A, Mulder N, Kneitz S.

PLoS One. 2013;8(2):e50695. doi: 10.1371/journal.pone.0050695. Epub 2013 Feb 1.

44.

Cystathionase mediates senescence evasion in melanocytes and melanoma cells.

Leikam C, Hufnagel A, Walz S, Kneitz S, Fekete A, Müller MJ, Eilers M, Schartl M, Meierjohann S.

Oncogene. 2014 Feb 6;33(6):771-82. doi: 10.1038/onc.2012.641. Epub 2013 Jan 28.

PMID:
23353821
45.

Sequential induction of effector function, tissue migration and cell death during polyclonal activation of mouse regulatory T-cells.

Langenhorst D, Gogishvili T, Ribechini E, Kneitz S, McPherson K, Lutz MB, Hünig T.

PLoS One. 2012;7(11):e50080. doi: 10.1371/journal.pone.0050080. Epub 2012 Nov 30.

46.

The stomatal response to reduced relative humidity requires guard cell-autonomous ABA synthesis.

Bauer H, Ache P, Lautner S, Fromm J, Hartung W, Al-Rasheid KA, Sonnewald S, Sonnewald U, Kneitz S, Lachmann N, Mendel RR, Bittner F, Hetherington AM, Hedrich R.

Curr Biol. 2013 Jan 7;23(1):53-7. doi: 10.1016/j.cub.2012.11.022. Epub 2012 Dec 6.

47.

Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction.

Frantz S, Hofmann U, Fraccarollo D, Schäfer A, Kranepuhl S, Hagedorn I, Nieswandt B, Nahrendorf M, Wagner H, Bayer B, Pachel C, Schön MP, Kneitz S, Bobinger T, Weidemann F, Ertl G, Bauersachs J.

FASEB J. 2013 Mar;27(3):871-81. doi: 10.1096/fj.12-214049. Epub 2012 Nov 16.

PMID:
23159933
48.

KCNIP4 as a candidate gene for personality disorders and adult ADHD.

Weißflog L, Scholz CJ, Jacob CP, Nguyen TT, Zamzow K, Groß-Lesch S, Renner TJ, Romanos M, Rujescu D, Walitza S, Kneitz S, Lesch KP, Reif A.

Eur Neuropsychopharmacol. 2013 Jun;23(6):436-47. doi: 10.1016/j.euroneuro.2012.07.017. Epub 2012 Sep 14.

PMID:
22981920
49.

The estrogen receptor-α is required and sufficient to maintain physiological glucose uptake in the mouse heart.

Arias-Loza PA, Kreissl MC, Kneitz S, Kaiser FR, Israel I, Hu K, Frantz S, Bayer B, Fritzemeier KH, Korach KS, Pelzer T.

Hypertension. 2012 Oct;60(4):1070-7. doi: 10.1161/HYPERTENSIONAHA.111.190389. Epub 2012 Aug 14.

50.

Conserved expression signatures between medaka and human pigment cell tumors.

Schartl M, Kneitz S, Wilde B, Wagner T, Henkel CV, Spaink HP, Meierjohann S.

PLoS One. 2012;7(5):e37880. doi: 10.1371/journal.pone.0037880. Epub 2012 May 31.

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