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Items: 11

1.

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma.

Bleu M, Gaulis S, Lopes R, Sprouffske K, Apfel V, Holwerda S, Pregnolato M, Yildiz U, Cordoʹ V, Dost AFM, Knehr J, Carbone W, Lohmann F, Lin CY, Bradner JE, Kauffmann A, Tordella L, Roma G, Galli GG.

Nat Commun. 2019 Aug 20;10(1):3739. doi: 10.1038/s41467-019-11672-1.

2.

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy.

Bertschi NL, Voorberg-van der Wel A, Zeeman AM, Schuierer S, Nigsch F, Carbone W, Knehr J, Gupta DK, Hofman SO, van der Werff N, Nieuwenhuis I, Klooster E, Faber BW, Flannery EL, Mikolajczak SA, Chuenchob V, Shrestha B, Beibel M, Bouwmeester T, Kangwanrangsan N, Sattabongkot J, Diagana TT, Kocken CH, Roma G.

Elife. 2018 Dec 27;7. pii: e41081. doi: 10.7554/eLife.41081.

3.

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte.

Plasschaert LW, Žilionis R, Choo-Wing R, Savova V, Knehr J, Roma G, Klein AM, Jaffe AB.

Nature. 2018 Aug;560(7718):377-381. doi: 10.1038/s41586-018-0394-6. Epub 2018 Aug 1.

4.

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy.

Potting C, Crochemore C, Moretti F, Nigsch F, Schmidt I, Manneville C, Carbone W, Knehr J, DeJesus R, Lindeman A, Maher R, Russ C, McAllister G, Reece-Hoyes JS, Hoffman GR, Roma G, Müller M, Sailer AW, Helliwell SB.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E180-E189. doi: 10.1073/pnas.1711023115. Epub 2017 Dec 21. Erratum in: Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8579.

5.

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi.

Voorberg-van der Wel A, Roma G, Gupta DK, Schuierer S, Nigsch F, Carbone W, Zeeman AM, Lee BH, Hofman SO, Faber BW, Knehr J, Pasini E, Kinzel B, Bifani P, Bonamy GMC, Bouwmeester T, Kocken CHM, Diagana TT.

Elife. 2017 Dec 7;6. pii: e29605. doi: 10.7554/eLife.29605.

6.

A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples.

Schuierer S, Carbone W, Knehr J, Petitjean V, Fernandez A, Sultan M, Roma G.

BMC Genomics. 2017 Jun 5;18(1):442. doi: 10.1186/s12864-017-3827-y.

7.

Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology.

Ley S, Galuba O, Salathe A, Melin N, Aebi A, Pikiolek M, Knehr J, Carbone W, Beibel M, Nigsch F, Roma G, d'Ario G, Kirkland S, Bouchez LC, Gubser Keller C, Bouwmeester T, Parker CN, Ruffner H.

SLAS Discov. 2017 Jun;22(5):571-582. doi: 10.1177/2472555216683651. Epub 2017 Jan 6.

PMID:
28345372
8.

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D.

Sci Rep. 2017 Feb 16;7:42728. doi: 10.1038/srep42728.

9.

Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening.

Kiessling MK, Schuierer S, Stertz S, Beibel M, Bergling S, Knehr J, Carbone W, de Vallière C, Tchinda J, Bouwmeester T, Seuwen K, Rogler G, Roma G.

BMC Genomics. 2016 Sep 9;17(1):723. doi: 10.1186/s12864-016-3042-2.

10.

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62.

DeJesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, Frias E, Alford J, Reece-Hoyes JS, Lindeman A, Kelliher J, Russ C, Knehr J, Carbone W, Beibel M, Roma G, Ng A, Tallarico JA, Porter JA, Xavier RJ, Mickanin C, Murphy LO, Hoffman GR, Nyfeler B.

Elife. 2016 Jun 28;5. pii: e17290. doi: 10.7554/eLife.17290.

11.

MiR-210 promotes sensory hair cell formation in the organ of corti.

Riccardi S, Bergling S, Sigoillot F, Beibel M, Werner A, Leighton-Davies J, Knehr J, Bouwmeester T, Parker CN, Roma G, Kinzel B.

BMC Genomics. 2016 Apr 27;17:309. doi: 10.1186/s12864-016-2620-7.

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