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Understanding parental perspectives on outcomes following paediatric encephalitis: A qualitative study.

Lemon J, Cooper J, Defres S, Easton A, Sadarangani M, Griffiths MJ, Pollard AJ, Solomon T, Kneen R.

PLoS One. 2019 Sep 16;14(9):e0220042. doi: 10.1371/journal.pone.0220042. eCollection 2019.


Utility and safety of plasma exchange in paediatric neuroimmune disorders.

Eyre M, Hacohen Y, Lamb K, Absoud M, Agrawal S, Gadian J, Gupta R, Kneen R, Milford DV, Philip S, Rose K, Smith M, Spinty S, Wassmer E, Lim M, Hemingway C.

Dev Med Child Neurol. 2019 May;61(5):540-546. doi: 10.1111/dmcn.14150. Epub 2019 Jan 18.


A pragmatic cluster randomised controlled trial of a tailored intervention to improve the initial management of suspected encephalitis.

Backman R, Foy R, Diggle PJ, Kneen R, Easton A, Defres S, McGill F, Michael BD, Solomon T; ENCEPH UK Programme Steering Committee.

PLoS One. 2018 Dec 6;13(12):e0202257. doi: 10.1371/journal.pone.0202257. eCollection 2018.


Clinical features, course, and outcomes of a UK cohort of pediatric moyamoya.

Tho-Calvi SC, Thompson D, Saunders D, Agrawal S, Basu A, Chitre M, Chow G, Gibbon F, Hart A, Tallur KK, Kirkham F, Kneen R, McCullagh H, Mewasingh L, Vassallo G, Vijayakumar K, Wraige E, Yeo TH, Ganesan V; British Paediatric Neurology Association Moyamoya Study group.

Neurology. 2018 Feb 27;90(9):e763-e770. doi: 10.1212/WNL.0000000000005026.


Clinical and molecular characterization of KCNT1-related severe early-onset epilepsy.

McTague A, Nair U, Malhotra S, Meyer E, Trump N, Gazina EV, Papandreou A, Ngoh A, Ackermann S, Ambegaonkar G, Appleton R, Desurkar A, Eltze C, Kneen R, Kumar AV, Lascelles K, Montgomery T, Ramesh V, Samanta R, Scott RH, Tan J, Whitehouse W, Poduri A, Scheffer IE, Chong WKK, Cross JH, Topf M, Petrou S, Kurian MA.

Neurology. 2018 Jan 2;90(1):e55-e66. doi: 10.1212/WNL.0000000000004762. Epub 2017 Dec 1.


The inter-rater reliability and prognostic value of coma scales in Nepali children with acute encephalitis syndrome.

Ray S, Rayamajhi A, Bonnett LJ, Solomon T, Kneen R, Griffiths MJ.

Paediatr Int Child Health. 2018 Feb;38(1):60-65. doi: 10.1080/20469047.2017.1398503. Epub 2017 Nov 16.


Current evidence-based recommendations on investigating children with global developmental delay.

Mithyantha R, Kneen R, McCann E, Gladstone M.

Arch Dis Child. 2017 Nov;102(11):1071-1076. doi: 10.1136/archdischild-2016-311271. Review.


Care beyond the hospital ward: understanding the socio-medical trajectory of herpes simplex virus encephalitis.

Cooper J, Kierans C, Defres S, Easton A, Kneen R, Solomon T; ENCEPH-UK study group.

BMC Health Serv Res. 2017 Sep 12;17(1):646. doi: 10.1186/s12913-017-2608-2.


Ketogenic diet in the treatment of epilepsy in children under the age of 2 years: study protocol for a randomised controlled trial.

Titre-Johnson S, Schoeler N, Eltze C, Williams R, Vezyroglou K, McCullagh H, Freemantle N, Heales S, Kneen R, Marston L, Martland T, Nazareth I, Neal E, Lux A, Parker A, Agrawal S, Fallon P, Cross JH.

Trials. 2017 Apr 26;18(1):195. doi: 10.1186/s13063-017-1918-3.


ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial.

Iro MA, Sadarangani M, Absoud M, Chong WK, Clark CA, Easton A, Gray V, Kneen R, Lim M, Pike M, Solomon T, Vincent A, Willis L, Yu LM, Pollard AJ.

BMJ Open. 2016 Nov 3;6(11):e012356. doi: 10.1136/bmjopen-2016-012356.


Subdural Empyema Caused by Neisseria meningitidis: A Case Report and Review of the Literature.

Ray S, Riordan A, Tawil M, Mallucci C, Jauhari P, Solomon T, Kneen R.

Pediatr Infect Dis J. 2016 Oct;35(10):1156-9. doi: 10.1097/INF.0000000000001252. Review.


Acquired torticollis due to primary pyomyositis of the paraspinal muscles in an 11-year-old boy.

Ray S, Iyer A, Avula S, Kneen R.

BMJ Case Rep. 2016 Mar 18;2016. pii: bcr2015213409. doi: 10.1136/bcr-2015-213409.


Diagnostic Pathways as Social and Participatory Practices: The Case of Herpes Simplex Encephalitis.

Cooper J, Kierans C, Defres S, Easton A, Kneen R, Solomon T.

PLoS One. 2016 Mar 9;11(3):e0151145. doi: 10.1371/journal.pone.0151145. eCollection 2016.


Herpesvirus Infections and Childhood Arterial Ischemic Stroke: Results of the VIPS Study.

Elkind MS, Hills NK, Glaser CA, Lo WD, Amlie-Lefond C, Dlamini N, Kneen R, Hod EA, Wintermark M, deVeber GA, Fullerton HJ; VIPS Investigators*.

Circulation. 2016 Feb 23;133(8):732-41. doi: 10.1161/CIRCULATIONAHA.115.018595. Epub 2016 Jan 26.


Anti-N-Methyl-D-Aspartate Receptor Encephalitis In A Young Child With Histological Evidence On Brain Biopsy Of Coexistent Herpes Simplex Virus Type 1 Infection.

Ellul MA, Griffiths MJ, Iyer A, Avula S, Defres S, Baborie A, Vincent A, Martin NG, Sadarangani M, Pollard AJ, Solomon T, Kneen R.

Pediatr Infect Dis J. 2016 Mar;35(3):347-9. doi: 10.1097/INF.0000000000001011.


Managing patients with encephalitis.

Matata C, Easton A, Michael B, Evans B, Ward D, Solomon T, Kneen R.

Nurs Stand. 2015 Nov 11;30(11):50-8; quiz 60. doi: 10.7748/ns.30.11.50.s47.


Performing lumbar punctures for suspected CNS infections: experience and practice of trainee doctors.

Defres S, Mayer J, Backman R, Kneen R.

Br J Hosp Med (Lond). 2015 Nov;76(11):658-62. doi: 10.12968/hmed.2015.76.11.658.


Correction: A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal.

Rayamajhi A, Nightingale S, Bhatta NK, Singh R, Ledger E, Bista KP, Lewthwaite P, Mahaseth C, Turtle L, Robinson JS, Galbraith SE, Wnek M, Johnson BW, Faragher B, Kneen R, Griffiths MJ, Solomon T.

PLoS One. 2015 Aug 13;10(8):e0136008. doi: 10.1371/journal.pone.0136008. eCollection 2015. No abstract available.


The development of an intervention to promote adherence to national guidelines for suspected viral encephalitis.

Backman R, Foy R, Michael BD, Defres S, Kneen R, Solomon T.

Implement Sci. 2015 Mar 20;10:37. doi: 10.1186/s13012-015-0224-2.


A preliminary randomized double blind placebo-controlled trial of intravenous immunoglobulin for Japanese encephalitis in Nepal.

Rayamajhi A, Nightingale S, Bhatta NK, Singh R, Kneen R, Ledger E, Bista KP, Lewthwaite P, Mahaseth C, Turtle L, Robinson JS, Galbraith SE, Wnek M, Johnson BW, Faragher B, Griffiths MJ, Solomon T.

PLoS One. 2015 Apr 17;10(4):e0122608. doi: 10.1371/journal.pone.0122608. eCollection 2015. Erratum in: PLoS One. 2015;10(8):e0136008. Kneen, Rachel [added].


The evaluation of a tailored intervention to improve the management of suspected viral encephalitis: protocol for a cluster randomised controlled trial.

Backman R, Foy R, Diggle PJ, Kneen R, Defres S, Michael BD, Medina-Lara A, Solomon T.

Implement Sci. 2015 Jan 27;10:14. doi: 10.1186/s13012-014-0201-1.


IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.

Baker GA, Bromley RL, Briggs M, Cheyne CP, Cohen MJ, García-Fiñana M, Gummery A, Kneen R, Loring DW, Mawer G, Meador KJ, Shallcross R, Clayton-Smith J; Liverpool and Manchester Neurodevelopment Group.

Neurology. 2015 Jan 27;84(4):382-90. doi: 10.1212/WNL.0000000000001182. Epub 2014 Dec 24.


Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease.

Dale RC, Brilot F, Duffy LV, Twilt M, Waldman AT, Narula S, Muscal E, Deiva K, Andersen E, Eyre MR, Eleftheriou D, Brogan PA, Kneen R, Alper G, Anlar B, Wassmer E, Heineman K, Hemingway C, Riney CJ, Kornberg A, Tardieu M, Stocco A, Banwell B, Gorman MP, Benseler SM, Lim M.

Neurology. 2014 Jul 8;83(2):142-50. doi: 10.1212/WNL.0000000000000570. Epub 2014 Jun 11.


PLA2G6-associated neurodegeneration (PLAN): further expansion of the clinical, radiological and mutation spectrum associated with infantile and atypical childhood-onset disease.

Illingworth MA, Meyer E, Chong WK, Manzur AY, Carr LJ, Younis R, Hardy C, McDonald F, Childs AM, Stewart B, Warren D, Kneen R, King MD, Hayflick SJ, Kurian MA.

Mol Genet Metab. 2014 Jun;112(2):183-9. doi: 10.1016/j.ymgme.2014.03.008. Epub 2014 Mar 29.


Neurological manifestations of influenza infection in children and adults: results of a National British Surveillance Study.

Goenka A, Michael BD, Ledger E, Hart IJ, Absoud M, Chow G, Lilleker J, Lunn M, McKee D, Peake D, Pysden K, Roberts M, Carrol ED, Lim M, Avula S, Solomon T, Kneen R.

Clin Infect Dis. 2014 Mar;58(6):775-84. doi: 10.1093/cid/cit922. Epub 2013 Dec 18.


Benign hereditary chorea related to NKX2.1: expansion of the genotypic and phenotypic spectrum.

Peall KJ, Lumsden D, Kneen R, Madhu R, Peake D, Gibbon F, Lewis H, Hedderly T, Meyer E, Robb SA, Lynch B, King MD, Lin JP, Morris HR, Jungbluth H, Kurian MA.

Dev Med Child Neurol. 2014 Jul;56(7):642-8. doi: 10.1111/dmcn.12323. Epub 2013 Oct 31.


Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a national surveillance cohort.

Hacohen Y, Absoud M, Woodhall M, Cummins C, De Goede CG, Hemingway C, Jardine PE, Kneen R, Pike MG, Whitehouse WP, Wassmer E, Waters P, Vincent A, Lim M; UK & Ireland Childhood CNS Inflammatory Demyelination Working Group.

J Neurol Neurosurg Psychiatry. 2014 Apr;85(4):456-61. doi: 10.1136/jnnp-2013-306411. Epub 2013 Oct 16.


The functional, social and economic impact of acute encephalitis syndrome in Nepal--a longitudinal follow-up study.

Griffiths MJ, Lemon JV, Rayamajhi A, Poudel P, Shrestha P, Srivastav V, Kneen R, Medina-Lara A, Singh RR, Solomon T.

PLoS Negl Trop Dis. 2013 Sep 12;7(9):e2383. doi: 10.1371/journal.pntd.0002383. eCollection 2013.


An investigation into the relationship between vigabatrin, movement disorders, and brain magnetic resonance imaging abnormalities in children with infantile spasms.

Fong CY, Osborne JP, Edwards SW, Hemingway C, Hancock E, Johnson AL, Kennedy CR, Kneen R, Likeman M, Lux AL, Mordekar SR, Murugan V, Newton RW, Pike M, Quinn M, Spinty S, Vassallo G, Verity CM, Whitney A, O'Callaghan FJ.

Dev Med Child Neurol. 2013 Sep;55(9):862-7. doi: 10.1111/dmcn.12188. Epub 2013 Jun 22.


Migrating partial seizures of infancy: expansion of the electroclinical, radiological and pathological disease spectrum.

McTague A, Appleton R, Avula S, Cross JH, King MD, Jacques TS, Bhate S, Cronin A, Curran A, Desurkar A, Farrell MA, Hughes E, Jefferson R, Lascelles K, Livingston J, Meyer E, McLellan A, Poduri A, Scheffer IE, Spinty S, Kurian MA, Kneen R.

Brain. 2013 May;136(Pt 5):1578-91. doi: 10.1093/brain/awt073. Epub 2013 Apr 18.


Limbic encephalitis associated with elevated antithyroid antibodies.

Hacohen Y, Joseph S, Kneen R, Eunson P, Lin JP, Vincent A, Lim M.

J Child Neurol. 2014 Jun;29(6):769-73. doi: 10.1177/0883073813480392. Epub 2013 Mar 20.


The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs.

Bromley RL, Mawer GE, Briggs M, Cheyne C, Clayton-Smith J, García-Fiñana M, Kneen R, Lucas SB, Shallcross R, Baker GA; Liverpool and Manchester Neurodevelopment Group.

J Neurol Neurosurg Psychiatry. 2013 Jun;84(6):637-43. doi: 10.1136/jnnp-2012-304270. Epub 2013 Jan 31.


Suboptimal management of central nervous system infections in children: a multi-centre retrospective study.

Kelly C, Sohal A, Michael BD, Riordan A, Solomon T, Kneen R; Northwest Neurological Infections Network.

BMC Pediatr. 2012 Sep 7;12:145. doi: 10.1186/1471-2431-12-145.


Congenital trigeminal anaesthesia: a rare preventable cause of visual loss in children.

Iyer A, Hassan E, Newman W, Kneen R.

BMJ Case Rep. 2012 Jul 3;2012. pii: bcr0320125955. doi: 10.1136/bcr.03.2012.5955.


Intravenous levetiracetam in acute repetitive seizures and status epilepticus in children: experience from a children's hospital.

McTague A, Kneen R, Kumar R, Spinty S, Appleton R.

Seizure. 2012 Sep;21(7):529-34. doi: 10.1016/j.seizure.2012.05.010. Epub 2012 Jun 19.


Improving the diagnosis of central nervous system infections in adults through introduction of a simple lumbar puncture pack.

Michael BD, Powell G, Curtis S, Bailey L, Almond S, McGill F, Cousins D, Hart IJ, Griffiths M, Kneen R, Solomon T.

Emerg Med J. 2013 May;30(5):402-5. doi: 10.1136/emermed-2012-201248. Epub 2012 Jun 15.


Childhood presentation of COL4A1 mutations.

Shah S, Ellard S, Kneen R, Lim M, Osborne N, Rankin J, Stoodley N, van der Knaap M, Whitney A, Jardine P.

Dev Med Child Neurol. 2012 Jun;54(6):569-74. doi: 10.1111/j.1469-8749.2011.04198.x. Epub 2012 Jan 16. Review.


Paediatric acquired demyelinating syndromes: incidence, clinical and magnetic resonance imaging features.

Absoud M, Lim MJ, Chong WK, De Goede CG, Foster K, Gunny R, Hemingway C, Jardine PE, Kneen R, Likeman M, Nischal KK, Pike MG, Sibtain NA, Whitehouse WP, Cummins C, Wassmer E; UK and Ireland Childhood CNS Inflammatory Demyelination Working Group.

Mult Scler. 2013 Jan;19(1):76-86. doi: 10.1177/1352458512445944. Epub 2012 Apr 19.


VGKC-complex antibody mediated encephalitis presenting with psychiatric features and neuroleptic malignant syndrome - further expanding the phenotype.

Iyer A, McTague A, Curran A, Inbasagaran A, Vincent A, Kneen R.

Dev Med Child Neurol. 2012 Jun;54(6):575-6. doi: 10.1111/j.1469-8749.2012.04249.x. Epub 2012 Mar 12. No abstract available.


COL4A1 mutations associated with a characteristic pattern of intracranial calcification.

Livingston J, Doherty D, Orcesi S, Tonduti D, Piechiecchio A, La Piana R, Tournier-Lasserve E, Majumdar A, Tomkins S, Rice G, Kneen R, van der Knaap M, Crow Y.

Neuropediatrics. 2011 Dec;42(6):227-33. doi: 10.1055/s-0031-1295493. Epub 2011 Dec 1.


Management of suspected viral encephalitis in adults--Association of British Neurologists and British Infection Association National Guidelines.

Solomon T, Michael BD, Smith PE, Sanderson F, Davies NW, Hart IJ, Holland M, Easton A, Buckley C, Kneen R, Beeching NJ; National Encephalitis Guidelines Development and Stakeholder Groups.

J Infect. 2012 Apr;64(4):347-73. doi: 10.1016/j.jinf.2011.11.014. Epub 2011 Nov 18.


Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group national guidelines.

Kneen R, Michael BD, Menson E, Mehta B, Easton A, Hemingway C, Klapper PE, Vincent A, Lim M, Carrol E, Solomon T; National Encephalitis Guidelines Development and Stakeholder Groups.

J Infect. 2012 May;64(5):449-77. doi: 10.1016/j.jinf.2011.11.013. Epub 2011 Nov 18.


Sulthiame in refractory paediatric epilepsies: an experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit.

Swiderska N, Hawcutt D, Eaton V, Stockton F, Kumar R, Kneen R, Appleton R.

Seizure. 2011 Dec;20(10):805-8. doi: 10.1016/j.seizure.2011.08.006. Epub 2011 Sep 15.


Paediatric UK demyelinating disease longitudinal study (PUDDLS).

Absoud M, Cummins C, Chong WK, De Goede C, Foster K, Gunny R, Hemingway C, Jardine P, Kneen R, Likeman M, Lim MJ, Pike M, Sibtain N, Whitehouse WP, Wassmer E.

BMC Pediatr. 2011 Jul 28;11:68. doi: 10.1186/1471-2431-11-68.


Encephalitis in children.

Thompson C, Kneen R, Riordan A, Kelly D, Pollard AJ.

Arch Dis Child. 2012 Feb;97(2):150-61. doi: 10.1136/archdischild-2011-300100. Epub 2011 Jun 28. Review.


Recurrence risk of epilepsy and mental retardation in females due to parental mosaicism of PCDH19 mutations.

Dibbens LM, Kneen R, Bayly MA, Heron SE, Arsov T, Damiano JA, Desai T, Gibbs J, McKenzie F, Mulley JC, Ronan A, Scheffer IE.

Neurology. 2011 Apr 26;76(17):1514-9. doi: 10.1212/WNL.0b013e318217e7b6.


Disability after encephalitis: development and validation of a new outcome score.

Lewthwaite P, Begum A, Ooi MH, Faragher B, Lai BF, Sandaradura I, Mohan A, Mandhan G, Meharwade P, Subhashini S, Abhishek G, Begum A, Penkulinti S, Shankar MV, Ravikumar R, Young C, Cardosa MJ, Ravi V, Wong SC, Kneen R, Solomon T.

Bull World Health Organ. 2010 Aug 1;88(8):584-92. doi: 10.2471/BLT.09.071357. Epub 2010 Apr 19.


Acute central nervous system infections in adults--a retrospective cohort study in the NHS North West region.

Michael BD, Sidhu M, Stoeter D, Roberts M, Beeching NJ, Bonington A, Hart IJ, Kneen R, Miller A, Solomon T; North West Neurological Infections Network.

QJM. 2010 Oct;103(10):749-58. doi: 10.1093/qjmed/hcq121. Epub 2010 Jul 24.


Effect of delayed lumbar punctures on the diagnosis of acute bacterial meningitis in adults.

Michael B, Menezes BF, Cunniffe J, Miller A, Kneen R, Francis G, Beeching NJ, Solomon T.

Emerg Med J. 2010 Jun;27(6):433-8. doi: 10.1136/emj.2009.075598. Epub 2010 Apr 1.


Effectiveness and tolerability of zonisamide in children with epilepsy: a retrospective review.

Tan HJ, Martland TR, Appleton RE, Kneen R.

Seizure. 2010 Jan;19(1):31-5. doi: 10.1016/j.seizure.2009.10.008. Epub 2009 Nov 25.

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