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Comparison between liver transplantation and resection for hilar cholangiocarcinoma: A systematic review and meta-analysis.

Moris D, Kostakis ID, Machairas N, Prodromidou A, Tsilimigras DI, Ravindra KV, Sudan DL, Knechtle SJ, Barbas AS.

PLoS One. 2019 Jul 31;14(7):e0220527. doi: 10.1371/journal.pone.0220527. eCollection 2019.


Translational impact of NIH-funded nonhuman primate research in transplantation.

Knechtle SJ, Shaw JM, Hering BJ, Kraemer K, Madsen JC.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaau0143. doi: 10.1126/scitranslmed.aau0143. Review.


Daratumumab in Sensitized Kidney Transplantation: Potentials and Limitations of Experimental and Clinical Use.

Kwun J, Matignon M, Manook M, Guendouz S, Audard V, Kheav D, Poullot E, Gautreau C, Ezekian B, Bodez D, Damy T, Faivre L, Menouch D, Yoon J, Park J, Belhadj K, Chen D, Bilewski AM, Yi JS, Collins B, Stegall M, Farris AB, Knechtle S, Grimbert P.

J Am Soc Nephrol. 2019 Jul;30(7):1206-1219. doi: 10.1681/ASN.2018121254. Epub 2019 Jun 21.


The past, present, and future of costimulation blockade in organ transplantation.

Schroder PM, Fitch ZW, Schmitz R, Choi AY, Kwun J, Knechtle SJ.

Curr Opin Organ Transplant. 2019 Aug;24(4):391-401. doi: 10.1097/MOT.0000000000000656.


Transplant research in nonhuman primates to evaluate clinically relevant immune strategies in organ transplantation.

Fitch Z, Schmitz R, Kwun J, Hering B, Madsen J, Knechtle SJ.

Transplant Rev (Orlando). 2019 Jul;33(3):115-129. doi: 10.1016/j.trre.2019.03.002. Epub 2019 Apr 5. Review.


Neuroendocrine carcinomas of the gallbladder: Lessons learnt from cases at opposite ends of the spectrum.

Moris D, Tsilimigras DI, Lim J, Camastra D, Nanavati A, Knechtle SJ, Barbas AS.

J BUON. 2018 Nov-Dec;23(6):1922-1926.


A Propensity-matched Survival Analysis: Do Simultaneous Liver-lung Transplant Recipients Need a Liver?

Freischlag K, Ezekian B, Schroder PM, Mulvihill MS, Cox ML, Hartwig MG, Knechtle S.

Transplantation. 2019 Aug;103(8):1675-1682. doi: 10.1097/TP.0000000000002529.


IL-21 Biased Alemtuzumab Induced Chronic Antibody-Mediated Rejection Is Reversed by LFA-1 Costimulation Blockade.

Kwun J, Park J, Yi JS, Farris AB, Kirk AD, Knechtle SJ.

Front Immunol. 2018 Oct 15;9:2323. doi: 10.3389/fimmu.2018.02323. eCollection 2018.


Improved contemporary outcomes of liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma.

Ezekian B, Mulvihill MS, Schroder PM, Gilmore BF, Leraas HJ, Gulack BC, Jane Commander S, Mavis AM, Kreissman SG, Knechtle SJ, Tracy ET, Barbas AS.

Pediatr Transplant. 2018 Dec;22(8):e13305. doi: 10.1111/petr.13305. Epub 2018 Oct 19.


Toward Long-term Livers.

Knechtle SJ.

Ann Surg. 2019 Jan;269(1):28-29. doi: 10.1097/SLA.0000000000003068. No abstract available.


Improved survival in simultaneous lung-liver recipients and candidates in the modern era of lung allocation.

Freischlag K, Schroder PM, Ezekian B, Cox ML, Mulvihill MS, Hartwig MG, Knechtle SJ.

J Surg Res. 2018 Nov;231:395-402. doi: 10.1016/j.jss.2018.06.007. Epub 2018 Jun 30.


The impact of human leukocyte antigen donor and recipient serotyping and matching on liver transplant graft failure in primary sclerosing cholangitis, autoimmune hepatitis, and primary biliary cholangitis.

Patel YA, Henson JB, Wilder JM, Zheng J, Chow SC, Berg CL, Knechtle SJ, Muir AJ.

Clin Transplant. 2018 Oct;32(10):e13388. doi: 10.1111/ctr.13388. Epub 2018 Sep 15.


Identification and Management of Abdominal Wall Varices in Pregnancy.

Wood AM, Grotegut CA, Ronald J, Pabon-Ramos W, Pedro C, Knechtle SJ, Wysokinska E, Rubin GD, Brady CW, Gilner JB.

Obstet Gynecol. 2018 Oct;132(4):882-887. doi: 10.1097/AOG.0000000000002805.


Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients.

Burghuber CK, Manook M, Ezekian B, Gibby AC, Leopardi FV, Song M, Jenks J, Saccoccio F, Permar S, Farris AB, Iwakoshi NN, Kwun J, Knechtle SJ.

Am J Transplant. 2019 Mar;19(3):724-736. doi: 10.1111/ajt.15067. Epub 2018 Sep 17.


Improvement in Liver Transplant Outcomes From Older Donors: A US National Analysis.

Gao Q, Mulvihill MS, Scheuermann U, Davis RP, Yerxa J, Yerokun BA, Hartwig MG, Sudan DL, Knechtle SJ, Barbas AS.

Ann Surg. 2019 Aug;270(2):333-339. doi: 10.1097/SLA.0000000000002876.


Innate networking: Thrombotic microangiopathy, the activation of coagulation and complement in the sensitized kidney transplant recipient.

Manook M, Kwun J, Sacks S, Dorling A, Mamode N, Knechtle S.

Transplant Rev (Orlando). 2018 Jul;32(3):119-126. doi: 10.1016/j.trre.2018.01.001. Epub 2018 Feb 10. Review.


Single-Center Long-Term Analysis of Combined Liver-Lung Transplant Outcomes.

Freischlag KW, Messina J, Ezekian B, Mulvihill MS, Barbas A, Berg C, Sudan D, Reynolds J, Hartwig M, Knechtle S.

Transplant Direct. 2018 Apr 26;4(5):e349. doi: 10.1097/TXD.0000000000000785. eCollection 2018 May.


Contemporary Strategies and Barriers to Transplantation Tolerance.

Ezekian B, Schroder PM, Freischlag K, Yoon J, Kwun J, Knechtle SJ.

Transplantation. 2018 Aug;102(8):1213-1222. doi: 10.1097/TP.0000000000002242. Review.


Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report.

Tambur AR, Campbell P, Claas FH, Feng S, Gebel HM, Jackson AM, Mannon RB, Reed EF, Tinckam K, Askar M, Chandraker A, Chang PP, Colvin M, Demetris AJ, Diamond JM, Dipchand AI, Fairchild RL, Ford ML, Friedewald J, Gill RG, Glotz D, Goldberg H, Hachem R, Knechtle S, Kobashigawa J, Levine DJ, Levitsky J, Mengel M, Milford E, Newell KA, O'Leary JG, Palmer S, Randhawa P, Smith J, Snyder L, Starling RC, Sweet S, Taner T, Taylor CJ, Woodle S, Zeevi A, Nickerson P.

Am J Transplant. 2018 Jul;18(7):1604-1614. doi: 10.1111/ajt.14752. Epub 2018 May 22.


Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates.

Kwun J, Burghuber C, Manook M, Ezekian B, Park J, Yoon J, Yi JS, Iwakoshi N, Gibby A, Hong JJ, Farris AB, Kirk AD, Knechtle SJ.

Blood Adv. 2017 Oct 26;1(24):2115-2119. doi: 10.1182/bloodadvances.2017010991. eCollection 2017 Nov 14. Erratum in: Blood Adv. 2018 Jan 23;2(2):89.


Commentary: Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation.

Schroder PM, Ezekian B, Ford M, Knechtle SJ, Kwun J.

Front Immunol. 2017 Nov 23;8:1615. doi: 10.3389/fimmu.2017.01615. eCollection 2017. No abstract available.


Infiltrative Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis Treated With a Single High-Dose Y90 Radioembolization and Subsequent Liver Transplantation Without a Recurrence.

Dendy MS, Camacho JC, Ludwig JM, Krasinskas AM, Knechtle SJ, Kim HS.

Transplant Direct. 2017 Aug 18;3(9):e206. doi: 10.1097/TXD.0000000000000707. eCollection 2017 Sep.


Elevated HbA1c in donor organs from patients without a diagnosis of diabetes portends worse liver allograft survival.

Ezekian B, Mulvihill MS, Freischlag K, Yerokun BA, Davis RP, Hartwig MG, Knechtle SJ, Barbas AS.

Clin Transplant. 2017 Sep;31(9). doi: 10.1111/ctr.13047. Epub 2017 Jul 21.


The Volume-outcome Relationship in Deceased Donor Kidney Transplantation and Implications for Regionalization.

Barbas AS, Dib MJ, Rege AS, Vikraman DS, Sudan DL, Knechtle SJ, Scarborough JE.

Ann Surg. 2018 Jun;267(6):1169-1172. doi: 10.1097/SLA.0000000000002351.


Humoral Compensation after Bortezomib Treatment of Allosensitized Recipients.

Kwun J, Burghuber C, Manook M, Iwakoshi N, Gibby A, Hong JJ, Knechtle S.

J Am Soc Nephrol. 2017 Jul;28(7):1991-1996. doi: 10.1681/ASN.2016070727. Epub 2017 Feb 23.


Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation.

Manook M, Kwun J, Burghuber C, Samy K, Mulvihill M, Yoon J, Xu H, MacDonald AL, Freischlag K, Curfman V, Branum E, Howell D, Farris AB, Smith RA, Sacks S, Dorling A, Mamode N, Knechtle SJ.

Am J Transplant. 2017 Aug;17(8):2055-2064. doi: 10.1111/ajt.14234. Epub 2017 Mar 23. Erratum in: Am J Transplant. 2017 Nov;17 (11):2993.


Crosstalk Between T and B Cells in the Germinal Center After Transplantation.

Kwun J, Manook M, Page E, Burghuber C, Hong J, Knechtle SJ.

Transplantation. 2017 Apr;101(4):704-712. doi: 10.1097/TP.0000000000001588. Review.


Bridging Locoregional Therapy Prolongs Survival in Patients Listed for Liver Transplant with Hepatocellular Carcinoma.

Xing M, Sakaria S, Dhanasekaran R, Parekh S, Spivey J, Knechtle SJ, Zhang D, Kim HS.

Cardiovasc Intervent Radiol. 2017 Mar;40(3):410-420. doi: 10.1007/s00270-016-1505-0. Epub 2016 Nov 29.


Expanding the Donor Pool With Normothermic Ex Vivo Liver Perfusion: The Future Is Now.

Barbas AS, Knechtle SJ.

Am J Transplant. 2016 Nov;16(11):3075-3076. doi: 10.1111/ajt.13959. Epub 2016 Aug 16. No abstract available.


Hypoxia of the growing liver accelerates regeneration.

Schadde E, Tsatsaris C, Swiderska-Syn M, Breitenstein S, Urner M, Schimmer R, Booy C, Z'graggen BR, Wenger RH, Spahn DR, Hertl M, Knechtle S, Diehl AM, Schläpfer M, Beck-Schimmer B.

Surgery. 2017 Mar;161(3):666-679. doi: 10.1016/j.surg.2016.05.018. Epub 2016 Jul 16.


Reply to: "Percutaneous Management of Benign Biliary Strictures: Is It Time to Focus on Reducing Procedure Invasiveness?".

Ludwig JM, Knechtle SJ, Kim HS.

J Vasc Interv Radiol. 2016 Jun;27(6):936-7. doi: 10.1016/j.jvir.2016.03.003. Epub 2016 Jun 3. No abstract available.


2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

Demetris AJ, Bellamy C, Hübscher SG, O'Leary J, Randhawa PS, Feng S, Neil D, Colvin RB, McCaughan G, Fung JJ, Del Bello A, Reinholt FP, Haga H, Adeyi O, Czaja AJ, Schiano T, Fiel MI, Smith ML, Sebagh M, Tanigawa RY, Yilmaz F, Alexander G, Baiocchi L, Balasubramanian M, Batal I, Bhan AK, Bucuvalas J, Cerski CTS, Charlotte F, de Vera ME, ElMonayeri M, Fontes P, Furth EE, Gouw ASH, Hafezi-Bakhtiari S, Hart J, Honsova E, Ismail W, Itoh T, Jhala NC, Khettry U, Klintmalm GB, Knechtle S, Koshiba T, Kozlowski T, Lassman CR, Lerut J, Levitsky J, Licini L, Liotta R, Mazariegos G, Minervini MI, Misdraji J, Mohanakumar T, Mölne J, Nasser I, Neuberger J, O'Neil M, Pappo O, Petrovic L, Ruiz P, Sağol Ö, Sanchez Fueyo A, Sasatomi E, Shaked A, Shiller M, Shimizu T, Sis B, Sonzogni A, Stevenson HL, Thung SN, Tisone G, Tsamandas AC, Wernerson A, Wu T, Zeevi A, Zen Y.

Am J Transplant. 2016 Oct;16(10):2816-2835. doi: 10.1111/ajt.13909. Epub 2016 Jul 14.


Rapamycin Interferes With Postdepletion Regulatory T Cell Homeostasis and Enhances DSA Formation Corrected by CTLA4-Ig.

Oh B, Yoon J, Farris A 3rd, Kirk A, Knechtle S, Kwun J.

Am J Transplant. 2016 Sep;16(9):2612-23. doi: 10.1111/ajt.13789. Epub 2016 Apr 8.


Regulating T Cell Behavior.

Knechtle SJ, Fairchild RL.

Am J Transplant. 2016 Jul;16(7):1949-50. doi: 10.1111/ajt.13724. Epub 2016 Mar 17. No abstract available.


Percutaneous Management of Benign Biliary Strictures with Large-Bore Catheters: Comparison between Patients with and without Orthotopic Liver Transplantation.

Ludwig JM, Webber GR, Knechtle SJ, Spivey JR, Xing M, Kim HS.

J Vasc Interv Radiol. 2016 Feb;27(2):219-225.e1. doi: 10.1016/j.jvir.2015.10.021. Epub 2015 Dec 17.


Antibody-Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology.

Burghuber CK, Kwun J, Page EJ, Manook M, Gibby AC, Leopardi FV, Song M, Farris AB 3rd, Hong JJ, Villinger F, Adams AB, Iwakoshi NN, Knechtle SJ.

Am J Transplant. 2016 Jun;16(6):1726-38. doi: 10.1111/ajt.13688. Epub 2016 Mar 25.


One Size Does Not Fit All--Regional Variation in the Impact of the Share 35 Liver Allocation Policy.

Halazun KJ, Mathur AK, Rana AA, Massie AB, Mohan S, Patzer RE, Wedd JP, Samstein B, Subramanian RM, Campos BD, Knechtle SJ.

Am J Transplant. 2016 Jan;16(1):137-42. doi: 10.1111/ajt.13500. Epub 2015 Nov 12.


Surgical technique in transplantation: how much does it matter?

Knechtle SJ, Sudan DL.

Am J Transplant. 2015 Nov;15(11):2791-2. doi: 10.1111/ajt.13484. No abstract available.


Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.

Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA.

Am J Transplant. 2015 Nov;15(11):2908-20. doi: 10.1111/ajt.13480. Epub 2015 Oct 13.


Equalizing MELD Scores Over Broad Geographies Is Not the Most Efficacious Way to Allocate a Scarce Resource in a Value-based Environment.

Reed A, Chapman WC, Knechtle S, Chavin K, Gilroy R, Klintmalm GB.

Ann Surg. 2015 Aug;262(2):220-3. doi: 10.1097/SLA.0000000000001331. No abstract available.


Impact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft.

Kwun J, Farris AB, Song H, Mahle WT, Burlingham WJ, Knechtle SJ.

Transplantation. 2015 Dec;99(12):2485-93. doi: 10.1097/TP.0000000000000805.


Urine Metabolite Profiles Predictive of Human Kidney Allograft Status.

Suhre K, Schwartz JE, Sharma VK, Chen Q, Lee JR, Muthukumar T, Dadhania DM, Ding R, Ikle DN, Bridges ND, Williams NM, Kastenmüller G, Karoly ED, Mohney RP, Abecassis M, Friedewald J, Knechtle SJ, Becker YT, Samstein B, Shaked A, Gross SS, Suthanthiran M.

J Am Soc Nephrol. 2016 Feb;27(2):626-36. doi: 10.1681/ASN.2015010107. Epub 2015 Jun 5.


Open-label prospective study of the safety and efficacy of glass-based yttrium 90 radioembolization for infiltrative hepatocellular carcinoma with portal vein thrombosis.

Kokabi N, Camacho JC, Xing M, El-Rayes BF, Spivey JR, Knechtle SJ, Kim HS.

Cancer. 2015 Jul 1;121(13):2164-74. doi: 10.1002/cncr.29275. Epub 2015 Apr 6.


Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model.

Kwun J, Page E, Hong JJ, Gibby A, Yoon J, Farris AB, Villinger F, Knechtle S.

Am J Transplant. 2015 Mar;15(3):815-22. doi: 10.1111/ajt.13045. Epub 2015 Feb 12.


The clinical relevance of alloantibody in liver transplantation.

Burghuber CK, Roberts TK, Knechtle SJ.

Transplant Rev (Orlando). 2015 Jan;29(1):16-22. doi: 10.1016/j.trre.2014.06.001. Epub 2014 Jul 22. Review.


The Association Between Hospital Finances and Complications After Complex Abdominal Surgery: Deficiencies in the Current Health Care Reimbursement System and Implications for the Future.

Knechtle WS, Perez SD, Medbery RL, Gartland BD, Sullivan PS, Knechtle SJ, Kooby DA, Maithel SK, Sarmiento JM, Shaffer VO, Srinivasan JK, Staley CA, Sweeney JF.

Ann Surg. 2015 Aug;262(2):273-9. doi: 10.1097/SLA.0000000000001042.


Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.

Velazquez VM, Uebelhoer LS, Thapa M, Ibegbu CC, Courtney C, Bosinger SE, Magliocca JF, Adams AB, Kirk AD, Knechtle SJ, Kalman D, Suthar MS, Grakoui A.

Hepatology. 2015 Mar;61(3):843-56. doi: 10.1002/hep.27575. Epub 2015 Jan 30.


Belatacept: is there BENEFIT for liver transplantation too?

Knechtle SJ, Adams AB.

Am J Transplant. 2014 Aug;14(8):1717-8.


Laparoscopic vs open right hepatectomy: a value-based analysis.

Medbery RL, Chadid TS, Sweeney JF, Knechtle SJ, Kooby DA, Maithel SK, Lin E, Sarmiento JM.

J Am Coll Surg. 2014 May;218(5):929-39. doi: 10.1016/j.jamcollsurg.2014.01.045. Epub 2014 Feb 14.


The role of donor-specific HLA alloantibodies in liver transplantation.

O'Leary JG, Demetris AJ, Friedman LS, Gebel HM, Halloran PF, Kirk AD, Knechtle SJ, McDiarmid SV, Shaked A, Terasaki PI, Tinckam KJ, Tomlanovich SJ, Wood KJ, Woodle ES, Zachary AA, Klintmalm GB.

Am J Transplant. 2014 Apr;14(4):779-87. doi: 10.1111/ajt.12667. Epub 2014 Mar 1.

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