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Items: 1 to 50 of 933

1.

Does Race Influence Decision Making for Advanced Heart Failure Therapies?

Breathett K, Yee E, Pool N, Hebdon M, Crist JD, Knapp S, Larsen A, Solola S, Luy L, Herrera-Theut K, Zabala L, Stone J, McEwen MM, Calhoun E, Sweitzer NK.

J Am Heart Assoc. 2019 Nov 19;8(22):e013592. doi: 10.1161/JAHA.119.013592. Epub 2019 Nov 11.

2.

A fast iterative synthetic approach towards the identification of novel highly selective p38 MAP kinase inhibitors.

Röhm S, Berger BT, Schröder M, Chaikuad A, Winkel R, Hekking KFW, Benningshof JJC, Mueller G, Tesch R, Kudolo M, Forster M, Laufer SA, Knapp S.

J Med Chem. 2019 Nov 8. doi: 10.1021/acs.jmedchem.9b01227. [Epub ahead of print]

PMID:
31702918
3.

Lessons from LIMK1 enzymology and their impact on inhibitor design.

Salah E, Chatterjee D, Beltrami A, Tumber A, Preuss F, Canning P, Chaikuad A, Knaus P, Knapp S, Bullock AN, Mathea S.

Biochem J. 2019 Nov 15;476(21):3197-3209. doi: 10.1042/BCJ20190517.

PMID:
31652302
4.

A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences.

Pollinger J, Schierle S, Gellrich L, Ohrndorf J, Kaiser A, Heitel P, Chaikuad A, Knapp S, Merk D.

ACS Med Chem Lett. 2019 Aug 16;10(9):1346-1352. doi: 10.1021/acsmedchemlett.9b00306. eCollection 2019 Sep 12.

PMID:
31531208
5.

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.

Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E.

J Med Chem. 2019 Sep 26;62(18):8443-8460. doi: 10.1021/acs.jmedchem.9b00445. Epub 2019 Sep 17.

PMID:
31436984
6.

Disease Resistance Genetics and Genomics in Octoploid Strawberry.

Barbey CR, Lee S, Verma S, Bird KA, Yocca AE, Edger PP, Knapp SJ, Whitaker VM, Folta KM.

G3 (Bethesda). 2019 Oct 7;9(10):3315-3332. doi: 10.1534/g3.119.400597.

7.

Dichotomous keys to the species of Solanum L. (Solanaceae) in continental Africa, Madagascar (incl. the Indian Ocean islands), Macaronesia and the Cape Verde Islands.

Knapp S, Vorontsova MS, Särkinen T.

PhytoKeys. 2019 Jul 19;127:39-76. doi: 10.3897/phytokeys.127.34326. eCollection 2019.

8.

Platelet PI3K Modulates Innate Leukocyte Extravasation during Acid-Induced Acute Lung Inflammation.

Kral-Pointner JB, Schrottmaier WC, Salzmann M, Mussbacher M, Schmidt GJ, Moser B, Heber S, Birnecker B, Paar H, Zellner M, Knapp S, Assinger A, Schabbauer G.

Thromb Haemost. 2019 Oct;19(10):1642-1654. doi: 10.1055/s-0039-1693693. Epub 2019 Aug 1.

PMID:
31370072
9.

Increasing Economic Burden in Hospitalized Patients With Cirrhosis: Analysis of a National Database.

Desai AP, Mohan P, Nokes B, Sheth D, Knapp S, Boustani M, Chalasani N, Fallon MB, Calhoun EA.

Clin Transl Gastroenterol. 2019 Jul;10(7):e00062. doi: 10.14309/ctg.0000000000000062.

10.

Alzheimer's disease medication and risk of all-cause mortality and all-cause hospitalization: A retrospective cohort study.

Bhattacharjee S, Patanwala AE, Lo-Ciganic WH, Malone DC, Lee JK, Knapp SM, Warholak T, Burke WJ.

Alzheimers Dement (N Y). 2019 Jul 10;5:294-302. doi: 10.1016/j.trci.2019.05.005. eCollection 2019.

11.

Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study.

Nené NR, Reisel D, Leimbach A, Franchi D, Jones A, Evans I, Knapp S, Ryan A, Ghazali S, Timms JF, Paprotka T, Bjørge L, Zikan M, Cibula D, Colombo N, Widschwendter M.

Lancet Oncol. 2019 Aug;20(8):1171-1182. doi: 10.1016/S1470-2045(19)30340-7. Epub 2019 Jul 9. Erratum in: Lancet Oncol. 2019 Sep;20(9):e468. Lancet Oncol. 2019 Oct;20(10):e559.

PMID:
31300207
12.

High-Throughput Purification of Protein Kinases from Escherichia coli and Insect Cells.

Mathea S, Salah E, Knapp S.

Methods Mol Biol. 2019;2025:191-202. doi: 10.1007/978-1-4939-9624-7_8.

PMID:
31267453
13.

The origins and adaptation of European potatoes reconstructed from historical genomes.

Gutaker RM, Weiß CL, Ellis D, Anglin NL, Knapp S, Luis Fernández-Alonso J, Prat S, Burbano HA.

Nat Ecol Evol. 2019 Jul;3(7):1093-1101. doi: 10.1038/s41559-019-0921-3. Epub 2019 Jun 24.

PMID:
31235927
14.

A revision of the Morelloid Clade of Solanum L. (Solanaceae) in North and Central America and the Caribbean.

Knapp S, Barboza GE, Bohs L, Särkinen T.

PhytoKeys. 2019 May 30;123:1-144. doi: 10.3897/phytokeys.123.31738. eCollection 2019.

15.

Interval Endurance and Resistance Training as Part of a Community-Based Secondary Prevention Program for Patients With Diabetes Mellitus and Coronary Artery Disease.

Christle JW, Knapp S, Geisberger M, Cervenka M, Moneghetti K, Myers J, Halle M, Boscheri A.

J Cardiopulm Rehabil Prev. 2019 Jun 11. doi: 10.1097/HCR.0000000000000426. [Epub ahead of print]

PMID:
31192806
16.

Operando Spectroscopic and Kinetic Characterization of Aerobic Allylic C-H Acetoxylation Catalyzed by Pd(OAc)2/4,5-Diazafluoren-9-one.

Jaworski JN, Kozack CV, Tereniak SJ, Knapp SMM, Landis CR, Miller JT, Stahl SS.

J Am Chem Soc. 2019 Jul 3;141(26):10462-10474. doi: 10.1021/jacs.9b04699. Epub 2019 Jun 25.

PMID:
31184479
17.

Identification of mutations in circulating cell-free tumour DNA as a biomarker in hepatocellular carcinoma.

Howell J, Atkinson SR, Pinato DJ, Knapp S, Ward C, Minisini R, Burlone ME, Leutner M, Pirisi M, Büttner R, Khan SA, Thursz M, Odenthal M, Sharma R.

Eur J Cancer. 2019 Jul;116:56-66. doi: 10.1016/j.ejca.2019.04.014. Epub 2019 Jun 4.

PMID:
31173963
18.

Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity.

Verdonck S, Pu SY, Sorrell FJ, Elkins JM, Froeyen M, Gao LJ, Prugar LI, Dorosky DE, Brannan JM, Barouch-Bentov R, Knapp S, Dye JM, Herdewijn P, Einav S, De Jonghe S.

J Med Chem. 2019 Jun 27;62(12):5810-5831. doi: 10.1021/acs.jmedchem.9b00136. Epub 2019 Jun 12.

PMID:
31136173
19.

Early consequences of allopolyploidy alter floral evolution in Nicotiana (Solanaceae).

McCarthy EW, Landis JB, Kurti A, Lawhorn AJ, Chase MW, Knapp S, Le Comber SC, Leitch AR, Litt A.

BMC Plant Biol. 2019 Apr 27;19(1):162. doi: 10.1186/s12870-019-1771-5.

20.

A chemical toolbox for the study of bromodomains and epigenetic signaling.

Wu Q, Heidenreich D, Zhou S, Ackloo S, Krämer A, Nakka K, Lima-Fernandes E, Deblois G, Duan S, Vellanki RN, Li F, Vedadi M, Dilworth J, Lupien M, Brennan PE, Arrowsmith CH, Müller S, Fedorov O, Filippakopoulos P, Knapp S.

Nat Commun. 2019 Apr 23;10(1):1915. doi: 10.1038/s41467-019-09672-2.

21.

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.

Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Tan L, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, Westover KD, Sorger PK, Gray NS.

Cell Chem Biol. 2019 Jun 20;26(6):818-829.e9. doi: 10.1016/j.chembiol.2019.02.021. Epub 2019 Apr 11.

PMID:
30982749
22.

Microbial Metabolites in Cystic Fibrosis: A Target for Future Therapy?

Widder S, Knapp S.

Am J Respir Cell Mol Biol. 2019 Aug;61(2):132-133. doi: 10.1165/rcmb.2019-0081ED. No abstract available.

23.

Grey mould of strawberry, a devastating disease caused by the ubiquitous necrotrophic fungal pathogen Botrytis cinerea.

Petrasch S, Knapp SJ, van Kan JAL, Blanco-Ulate B.

Mol Plant Pathol. 2019 Jun;20(6):877-892. doi: 10.1111/mpp.12794. Epub 2019 Apr 4. Review.

24.

Extent and Predictors of Potentially Inappropriate Antidepressant Use Among Older Adults With Dementia and Major Depressive Disorder.

Bhattacharjee S, Lee JK, Patanwala AE, Vadiei N, Malone DC, Knapp SM, Lo-Ciganic WH, Burke WJ.

Am J Geriatr Psychiatry. 2019 Aug;27(8):794-805. doi: 10.1016/j.jagp.2019.02.002. Epub 2019 Feb 7.

PMID:
30926273
25.

Infection Strategies Deployed by Botrytis cinerea, Fusarium acuminatum, and Rhizopus stolonifer as a Function of Tomato Fruit Ripening Stage.

Petrasch S, Silva CJ, Mesquida-Pesci SD, Gallegos K, van den Abeele C, Papin V, Fernandez-Acero FJ, Knapp SJ, Blanco-Ulate B.

Front Plant Sci. 2019 Mar 1;10:223. doi: 10.3389/fpls.2019.00223. eCollection 2019.

26.

Solanummedusae (Solanaceae), a new wolf-fruit from Brazil, and a key to the extra-Amazonian Brazilian Androceras/Crinitum Clade species.

Gouvêa YF, Tehmann JR, Knapp S.

PhytoKeys. 2019 Feb 27;(118):15-32. doi: 10.3897/phytokeys.118.31598. eCollection 2019.

27.

Author Correction: Origin and evolution of the octoploid strawberry genome.

Edger PP, Poorten TJ, VanBuren R, Hardigan MA, Colle M, McKain MR, Smith RD, Teresi SJ, Nelson ADL, Wai CM, Alger EI, Bird KA, Yocca AE, Pumplin N, Ou S, Ben-Zvi G, Brodt A, Baruch K, Swale T, Shiue L, Acharya CB, Cole GS, Mower JP, Childs KL, Jiang N, Lyons E, Freeling M, Puzey JR, Knapp SJ.

Nat Genet. 2019 Apr;51(4):765. doi: 10.1038/s41588-019-0380-4.

PMID:
30842601
28.

Origin and evolution of the octoploid strawberry genome.

Edger PP, Poorten TJ, VanBuren R, Hardigan MA, Colle M, McKain MR, Smith RD, Teresi SJ, Nelson ADL, Wai CM, Alger EI, Bird KA, Yocca AE, Pumplin N, Ou S, Ben-Zvi G, Brodt A, Baruch K, Swale T, Shiue L, Acharya CB, Cole GS, Mower JP, Childs KL, Jiang N, Lyons E, Freeling M, Puzey JR, Knapp SJ.

Nat Genet. 2019 Mar;51(3):541-547. doi: 10.1038/s41588-019-0356-4. Epub 2019 Feb 25. Erratum in: Nat Genet. 2019 Apr;51(4):765.

PMID:
30804557
29.

Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

Watts E, Heidenreich D, Tucker E, Raab M, Strebhardt K, Chesler L, Knapp S, Bellenie B, Hoelder S.

J Med Chem. 2019 Mar 14;62(5):2618-2637. doi: 10.1021/acs.jmedchem.8b01947. Epub 2019 Feb 21.

30.

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2).

Chaikuad A, Koschade SE, Stolz A, Zivkovic K, Pohl C, Shaid S, Ren H, Lambert LJ, Cosford NDP, Brandts CH, Knapp S.

Biochem J. 2019 Mar 12;476(5):875-887. doi: 10.1042/BCJ20190038.

PMID:
30782972
31.

SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK).

Asquith CRM, Berger BT, Wan J, Bennett JM, Capuzzi SJ, Crona DJ, Drewry DH, East MP, Elkins JM, Fedorov O, Godoi PH, Hunter DM, Knapp S, Müller S, Torrice CD, Wells CI, Earp HS, Willson TM, Zuercher WJ.

J Med Chem. 2019 Mar 14;62(5):2830-2836. doi: 10.1021/acs.jmedchem.8b01213. Epub 2019 Feb 26.

32.

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

Tazarki H, Zeinyeh W, Esvan YJ, Knapp S, Chatterjee D, Schröder M, Joerger AC, Khiari J, Josselin B, Baratte B, Bach S, Ruchaud S, Anizon F, Giraud F, Moreau P.

Eur J Med Chem. 2019 Mar 15;166:304-317. doi: 10.1016/j.ejmech.2019.01.052. Epub 2019 Jan 26.

PMID:
30731399
33.

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27.

34.

Single-Molecule Protein Phosphorylation and Dephosphorylation by Nanopore Enzymology.

Harrington L, Alexander LT, Knapp S, Bayley H.

ACS Nano. 2019 Jan 22;13(1):633-641. doi: 10.1021/acsnano.8b07697. Epub 2019 Jan 4.

PMID:
30588793
35.

Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.

Němec V, Hylsová M, Maier L, Flegel J, Sievers S, Ziegler S, Schröder M, Berger BT, Chaikuad A, Valčíková B, Uldrijan S, Drápela S, Souček K, Waldmann H, Knapp S, Paruch K.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1062-1066. doi: 10.1002/anie.201810312. Epub 2018 Dec 20.

PMID:
30569600
36.

Early-Life Formation of the Microbial and Immunological Environment of the Human Airways.

Pattaroni C, Watzenboeck ML, Schneidegger S, Kieser S, Wong NC, Bernasconi E, Pernot J, Mercier L, Knapp S, Nicod LP, Marsland CP, Roth-Kleiner M, Marsland BJ.

Cell Host Microbe. 2018 Dec 12;24(6):857-865.e4. doi: 10.1016/j.chom.2018.10.019. Epub 2018 Nov 29.

PMID:
30503510
37.

Domestication of Temperate and Coastal Hybrids with Distinct Ancestral Gene Selection in Octoploid Strawberry.

Hardigan MA, Poorten TJ, Acharya CB, Cole GS, Hummer KE, Bassil N, Edger PP, Knapp SJ.

Plant Genome. 2018 Nov;11(3). doi: 10.3835/plantgenome2018.07.0049.

38.

Correction to "Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID subunit 1".

Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV.

Biochemistry. 2018 Dec 11;57(49):6806. doi: 10.1021/acs.biochem.8b01187. Epub 2018 Nov 28. No abstract available.

PMID:
30485080
39.

Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).

Heidenreich D, Moustakim M, Schmidt J, Merk D, Brennan PE, Fedorov O, Chaikuad A, Knapp S.

J Med Chem. 2018 Dec 13;61(23):10929-10934. doi: 10.1021/acs.jmedchem.8b01457. Epub 2018 Nov 26.

PMID:
30407816
40.

A Pseudo-Kinase Double Act.

Preuß F, Mathea S, Knapp S.

Structure. 2018 Nov 6;26(11):1564. doi: 10.1016/j.str.2018.10.019. No abstract available.

41.

Interleukin 28A.rs12980602 and interleukin 28B.rs8103142 genotypes could be protective against HCV infection among Egyptians.

Zakaria ZA, Knapp S, Hashem M, Zaghla H, Thursz M, Waked I, Abdelwahab S.

Immunol Res. 2019 Feb;67(1):123-133. doi: 10.1007/s12026-018-9035-2.

PMID:
30402710
42.

Binding Kinetics Survey of the Drugged Kinome.

Georgi V, Schiele F, Berger BT, Steffen A, Marin Zapata PA, Briem H, Menz S, Preusse C, Vasta JD, Robers MB, Brands M, Knapp S, Fernández-Montalván A.

J Am Chem Soc. 2018 Nov 21;140(46):15774-15782. doi: 10.1021/jacs.8b08048. Epub 2018 Nov 6.

PMID:
30362749
43.

Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase.

Juettner NE, Schmelz S, Kraemer A, Knapp S, Becker B, Kolmar H, Scrima A, Fuchsbauer HL.

FEBS J. 2018 Dec;285(24):4684-4694. doi: 10.1111/febs.14678. Epub 2018 Oct 26.

PMID:
30318745
44.

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting.

Cohen M, Giladi A, Gorki AD, Solodkin DG, Zada M, Hladik A, Miklosi A, Salame TM, Halpern KB, David E, Itzkovitz S, Harkany T, Knapp S, Amit I.

Cell. 2018 Nov 1;175(4):1031-1044.e18. doi: 10.1016/j.cell.2018.09.009. Epub 2018 Oct 11.

45.

Discovery of an MLLT1/3 YEATS Domain Chemical Probe.

Moustakim M, Christott T, Monteiro OP, Bennett J, Giroud C, Ward J, Rogers CM, Smith P, Panagakou I, Díaz-Sáez L, Felce SL, Gamble V, Gileadi C, Halidi N, Heidenreich D, Chaikuad A, Knapp S, Huber KVM, Farnie G, Heer J, Manevski N, Poda G, Al-Awar R, Dixon DJ, Brennan PE, Fedorov O.

Angew Chem Int Ed Engl. 2018 Dec 10;57(50):16302-16307. doi: 10.1002/anie.201810617. Epub 2018 Nov 16.

46.

A new black nightshade (Morelloid clade, Solanum, Solanaceae) from the caatinga biome of north-eastern Brazil with a key to Brazilian morelloids.

Knapp S, Särkinen T.

PhytoKeys. 2018 Aug 13;(108):1-12. doi: 10.3897/phytokeys.108.27254. eCollection 2018.

47.

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Infection. 2018 Oct;46(5):745-747. doi: 10.1007/s15010-018-1197-2.

48.

A global meta-analysis of yield stability in organic and conservation agriculture.

Knapp S, van der Heijden MGA.

Nat Commun. 2018 Sep 7;9(1):3632. doi: 10.1038/s41467-018-05956-1.

49.

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.

Ngeow KC, Friedrichsen HJ, Li L, Zeng Z, Andrews S, Volpon L, Brunsdon H, Berridge G, Picaud S, Fischer R, Lisle R, Knapp S, Filippakopoulos P, Knowles H, Steingrímsson E, Borden KLB, Patton EE, Goding CR.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8668-E8677. doi: 10.1073/pnas.1810498115. Epub 2018 Aug 27.

50.

Right ventricular afterload predicts long-term transition from parenteral to oral treprostinil in pulmonary arterial hypertension.

Maestas T, Hansen LM, Vanderpool RR, Desai AA, Airhart S, Knapp SM, Cohen A, Feldman J, Rischard FP.

Pulm Circ. 2018 Oct-Dec;8(4):2045894018797270. doi: 10.1177/2045894018797270. Epub 2018 Aug 20.

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