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Items: 1 to 50 of 887

1.

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Infection. 2018 Sep 17. doi: 10.1007/s15010-018-1197-2. [Epub ahead of print]

PMID:
30225655
2.

A global meta-analysis of yield stability in organic and conservation agriculture.

Knapp S, van der Heijden MGA.

Nat Commun. 2018 Sep 7;9(1):3632. doi: 10.1038/s41467-018-05956-1.

3.

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.

Ngeow KC, Friedrichsen HJ, Li L, Zeng Z, Andrews S, Volpon L, Brunsdon H, Berridge G, Picaud S, Fischer R, Lisle R, Knapp S, Filippakopoulos P, Knowles H, Steingrímsson E, Borden KLB, Patton EE, Goding CR.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8668-E8677. doi: 10.1073/pnas.1810498115. Epub 2018 Aug 27.

PMID:
30150413
4.

Right ventricular afterload predicts long-term transition from parenteral to oral treprostinil in pulmonary arterial hypertension.

Maestas T, Hansen LM, Vanderpool RR, Desai AA, Airhart S, Knapp SM, Cohen A, Feldman J, Rischard FP.

Pulm Circ. 2018 Oct-Dec;8(4):2045894018797270. doi: 10.1177/2045894018797270. Epub 2018 Aug 20.

5.

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Joost Wiersinga W, Xiao X, Zingarelli B.

Intensive Care Med Exp. 2018 Aug 14;6(1):26. doi: 10.1186/s40635-018-0189-y. Review.

6.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman CS, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Shock. 2018 Oct;50(4):377-380. doi: 10.1097/SHK.0000000000001212.

7.

Part II: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS) for Types of Infections and Organ Dysfunction Endpoints.

Libert C, Ayala A, Bauer M, Cavaillon JM, Deutschman C, Frostell C, Knapp S, Kozlov AV, Wang P, Osuchowski MF, Remick DG.

Shock. 2018 Aug 14. doi: 10.1097/SHK.0000000000001242. [Epub ahead of print]

PMID:
30106873
8.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Infection. 2018 Aug 14. doi: 10.1007/s15010-018-1183-8. [Epub ahead of print] Review. Erratum in: Infection. 2018 Sep 17;:.

PMID:
30105433
9.

Shedding new light on the origin and spread of the brinjal eggplant (Solanum melongena L.) and its wild relatives.

Aubriot X, Knapp S, Syfert MM, Poczai P, Buerki S.

Am J Bot. 2018 Jul;105(7):1175-1187. doi: 10.1002/ajb2.1133. Epub 2018 Aug 9.

PMID:
30091787
10.

A revision of the Old World Black Nightshades (Morelloid clade of Solanum L., Solanaceae).

Särkinen T, Poczai P, Barboza GE, van der Weerden GM, Baden M, Knapp S.

PhytoKeys. 2018 Jul 25;(106):1-223. doi: 10.3897/phytokeys.106.21991. eCollection 2018.

11.

Targeting Pim Kinases and DAPK3 to Control Hypertension.

Carlson DA, Singer MR, Sutherland C, Redondo C, Alexander LT, Hughes PF, Knapp S, Gurley SB, Sparks MA, MacDonald JA, Haystead TAJ.

Cell Chem Biol. 2018 Jul 4. pii: S2451-9456(18)30220-4. doi: 10.1016/j.chembiol.2018.06.006. [Epub ahead of print]

PMID:
30033129
12.

Chemoproteomics and Chemical Probes for Target Discovery.

Drewes G, Knapp S.

Trends Biotechnol. 2018 Jul 12. pii: S0167-7799(18)30172-0. doi: 10.1016/j.tibtech.2018.06.008. [Epub ahead of print] Review.

PMID:
30017093
13.

PhytoKeys at 100: progress in sustainability, innovation, and speed to enhance publication in plant systematics.

Kress WJ, Knapp S, Stoev P, Penev L.

PhytoKeys. 2018 Jun 21;(100):1-9. doi: 10.3897/phytokeys.100.27591. eCollection 2018. No abstract available.

14.

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.

Casey AE, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, Cruickshank J, Shehata M, Drysdale E, Fang H, Kim H, Isserlin R, Bailey S, Medina T, Deblois G, Shiah YJ, Barsyte-Lovejoy D, Hofer S, Bader G, Lupien M, Arrowsmith C, Knapp S, De Carvalho D, Berman H, Boutros PC, Kislinger T, Khokha R.

J Cell Biol. 2018 Aug 6;217(8):2951-2974. doi: 10.1083/jcb.201804042. Epub 2018 Jun 19.

15.

STK3 is a therapeutic target for a subset of acute myeloid leukemias.

Camgoz A, Paszkowski-Rogacz M, Satpathy S, Wermke M, Hamann MV, von Bonin M, Choudhary C, Knapp S, Buchholz F.

Oncotarget. 2018 May 22;9(39):25458-25473. doi: 10.18632/oncotarget.25238. eCollection 2018 May 22.

16.

Large-scale analysis of water stability in bromodomain binding pockets with grand canonical Monte Carlo.

Aldeghi M, Ross GA, Bodkin MJ, Essex JW, Knapp S, Biggin PC.

Commun Chem. 2018 Apr 5;1. pii: 19. doi: 10.1038/s42004-018-0019-x.

17.

Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold.

Forster M, Chaikuad A, Dimitrov T, Döring E, Holstein J, Berger BT, Gehringer M, Ghoreschi K, Müller S, Knapp S, Laufer SA.

J Med Chem. 2018 Jun 28;61(12):5350-5366. doi: 10.1021/acs.jmedchem.8b00571. Epub 2018 Jun 13.

PMID:
29852068
18.

Formal [4 + 2] cycloaddition of imines with alkoxyisocoumarins.

Jarvis CL, Jemal NM, Knapp S, Seidel D.

Org Biomol Chem. 2018 Jun 13;16(23):4231-4235. doi: 10.1039/c8ob01015c.

PMID:
29796555
19.

Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype.

Walter A, Chaikuad A, Helmer R, Loaëc N, Preu L, Ott I, Knapp S, Meijer L, Kunick C.

PLoS One. 2018 May 3;13(5):e0196761. doi: 10.1371/journal.pone.0196761. eCollection 2018.

20.

Co-targeting of BET proteins and HDACs as a novel approach to trigger apoptosis in rhabdomyosarcoma cells.

Enßle JC, Boedicker C, Wanior M, Vogler M, Knapp S, Fulda S.

Cancer Lett. 2018 Aug 1;428:160-172. doi: 10.1016/j.canlet.2018.04.032. Epub 2018 Apr 27.

PMID:
29709701
21.

Donated chemical probes for open science.

Müller S, Ackloo S, Arrowsmith CH, Bauser M, Baryza JL, Blagg J, Böttcher J, Bountra C, Brown PJ, Bunnage ME, Carter AJ, Damerell D, Dötsch V, Drewry DH, Edwards AM, Edwards J, Elkins JM, Fischer C, Frye SV, Gollner A, Grimshaw CE, IJzerman A, Hanke T, Hartung IV, Hitchcock S, Howe T, Hughes TV, Laufer S, Li VM, Liras S, Marsden BD, Matsui H, Mathias J, O'Hagan RC, Owen DR, Pande V, Rauh D, Rosenberg SH, Roth BL, Schneider NS, Scholten C, Singh Saikatendu K, Simeonov A, Takizawa M, Tse C, Thompson PR, Treiber DK, Viana AY, Wells CI, Willson TM, Zuercher WJ, Knapp S, Mueller-Fahrnow A.

Elife. 2018 Apr 20;7. pii: e34311. doi: 10.7554/eLife.34311.

22.

A Pseudo-Kinase Double Act.

Preuß F, Mathea S, Knapp S.

Structure. 2018 Apr 3;26(4):527-528. doi: 10.1016/j.str.2018.03.008.

PMID:
29617648
23.

Genome-Wide Association Mapping Uncovers Fw1, a Dominant Gene Conferring Resistance to Fusarium Wilt in Strawberry.

Pincot DDA, Poorten TJ, Hardigan MA, Harshman JM, Acharya CB, Cole GS, Gordon TR, Stueven M, Edger PP, Knapp SJ.

G3 (Bethesda). 2018 May 4;8(5):1817-1828. doi: 10.1534/g3.118.200129.

24.

Halogen-Aromatic π Interactions Modulate Inhibitor Residence Times.

Heroven C, Georgi V, Ganotra GK, Brennan P, Wolfreys F, Wade RC, Fernández-Montalván AE, Chaikuad A, Knapp S.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7220-7224. doi: 10.1002/anie.201801666. Epub 2018 May 9.

PMID:
29601130
25.

Identifying Small-Molecule Binding Sites for Epigenetic Proteins at Domain-Domain Interfaces.

Bowkett D, Talon R, Tallant C, Schofield C, von Delft F, Knapp S, Bruton G, Brennan PE.

ChemMedChem. 2018 May 23;13(10):1051-1057. doi: 10.1002/cmdc.201800030. Epub 2018 Apr 17.

26.

BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells.

Wroblewski M, Scheller-Wendorff M, Udonta F, Bauer R, Schlichting J, Zhao L, Ben Batalla I, Gensch V, Päsler S, Wu L, Wanior M, Taipaleenmäki H, Bolamperti S, Najafova Z, Pantel K, Bokemeyer C, Qi J, Hesse E, Knapp S, Johnsen S, Loges S.

Haematologica. 2018 Jun;103(6):939-948. doi: 10.3324/haematol.2017.181354. Epub 2018 Mar 22.

27.

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.

Moustakim M, Riedel K, Schuller M, Gehring AP, Monteiro OP, Martin SP, Fedorov O, Heer J, Dixon DJ, Elkins JM, Knapp S, Bracher F, Brennan PE.

Bioorg Med Chem. 2018 Jul 15;26(11):2965-2972. doi: 10.1016/j.bmc.2018.03.020. Epub 2018 Mar 12.

28.

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1.

Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV.

Biochemistry. 2018 Apr 10;57(14):2140-2149. doi: 10.1021/acs.biochem.8b00150. Epub 2018 Mar 28.

29.

New opportunities for kinase drug repurposing and target discovery.

Knapp S.

Br J Cancer. 2018 Apr;118(7):936-937. doi: 10.1038/s41416-018-0045-6. Epub 2018 Mar 16.

PMID:
29545596
30.

A new commelinid monocot seed fossil from the early Eocene previously identified as Solanaceae.

Särkinen T, Kottner S, Stuppy W, Ahmed F, Knapp S.

Am J Bot. 2018 Jan;105(1):95-107. doi: 10.1002/ajb2.1009. Epub 2018 Feb 12.

PMID:
29532926
31.

θ-Defensins-A Magic Bullet for Acute Lung Injury?

Knapp S.

Am J Respir Cell Mol Biol. 2018 Mar;58(3):277-278. doi: 10.1165/rcmb.2017-0368ED. No abstract available.

PMID:
29493326
32.

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Felici M, Behrends C, Klinger FG, Dötsch V.

Nat Struct Mol Biol. 2018 Mar;25(3):261-269. doi: 10.1038/s41594-018-0035-7. Epub 2018 Feb 26.

PMID:
29483652
33.

Computational assessment of thioether isosteres.

Barrows RD, Blacklock KM, Rablen PR, Khare SD, Knapp S.

J Mol Graph Model. 2018 Mar;80:282-292. doi: 10.1016/j.jmgm.2018.01.018. Epub 2018 Feb 1.

PMID:
29414047
34.

Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Karaminejadranjbar M, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA.

Nat Commun. 2018 Feb 2;9(1):476. doi: 10.1038/s41467-017-02811-7.

35.

Digest: Shape-shifting in Solanaceae flowers: The influence of pollinators.

Dodsworth S, Orejuela A, Pérez-Escobar OA, Särkinen T, Knapp S.

Evolution. 2018 Mar;72(3):717-718. doi: 10.1111/evo.13437. Epub 2018 Mar 1. No abstract available.

PMID:
29380354
36.

Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.

Perugorria MJ, Esparza-Baquer A, Oakley F, Labiano I, Korosec A, Jais A, Mann J, Tiniakos D, Santos-Laso A, Arbelaiz A, Gawish R, Sampedro A, Fontanellas A, Hijona E, Jimenez-Agüero R, Esterbauer H, Stoiber D, Bujanda L, Banales JM, Knapp S, Sharif O, Mann DA.

Gut. 2018 Jan 27. pii: gutjnl-2017-314107. doi: 10.1136/gutjnl-2017-314107. [Epub ahead of print]

37.

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.

Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E.

PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018.

38.

Stereochemistry and Reactivity of the HPA-Imine Mannich Intermediate.

Polyak D, Phung N, Liu J, Barrows R, Emge TJ, Knapp S.

Tetrahedron Lett. 2017 Oct 4;58(40):3879-3883. doi: 10.1016/j.tetlet.2017.08.070. Epub 2017 Aug 31.

PMID:
29276314
39.

Single-molecule sequencing and optical mapping yields an improved genome of woodland strawberry (Fragaria vesca) with chromosome-scale contiguity.

Edger PP, VanBuren R, Colle M, Poorten TJ, Wai CM, Niederhuth CE, Alger EI, Ou S, Acharya CB, Wang J, Callow P, McKain MR, Shi J, Collier C, Xiong Z, Mower JP, Slovin JP, Hytönen T, Jiang N, Childs KL, Knapp SJ.

Gigascience. 2018 Feb 1;7(2):1-7. doi: 10.1093/gigascience/gix124.

40.

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement.

Vasta JD, Corona CR, Wilkinson J, Zimprich CA, Hartnett JR, Ingold MR, Zimmerman K, Machleidt T, Kirkland TA, Huwiler KG, Ohana RF, Slater M, Otto P, Cong M, Wells CI, Berger BT, Hanke T, Glas C, Ding K, Drewry DH, Huber KVM, Willson TM, Knapp S, Müller S, Meisenheimer PL, Fan F, Wood KV, Robers MB.

Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. doi: 10.1016/j.chembiol.2017.10.010. Epub 2017 Nov 22.

41.

Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.

Shadrick WR, Slavish PJ, Chai SC, Waddell B, Connelly M, Low JA, Tallant C, Young BM, Bharatham N, Knapp S, Boyd VA, Morfouace M, Roussel MF, Chen T, Lee RE, Kiplin Guy R, Shelat AA, Potter PM.

Bioorg Med Chem. 2018 Jan 1;26(1):25-36. doi: 10.1016/j.bmc.2017.10.042. Epub 2017 Nov 4.

PMID:
29170024
42.

The Type 1 Diabetes-Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice.

Whitener RL, Gallo Knight L, Li J, Knapp S, Zhang S, Annamalai M, Pliner VM, Fu D, Radichev I, Amatya C, Savinov A, Yurdagul A Jr, Yuan S, Glawe J, Kevil CG, Chen J, Stimpson SE, Mathews CE.

J Immunol. 2017 Dec 15;199(12):3991-4000. doi: 10.4049/jimmunol.1602037. Epub 2017 Nov 6.

PMID:
29109122
43.

Heme and hemolysis in innate immunity: adding insult to injury.

Martins R, Knapp S.

Curr Opin Immunol. 2018 Feb;50:14-20. doi: 10.1016/j.coi.2017.10.005. Epub 2017 Nov 5. Review.

PMID:
29107115
44.

Estimating the potential biodiversity impact of redeveloping small urban spaces: the Natural History Museum's grounds.

Phillips HRP, Knapp S, Purvis A.

PeerJ. 2017 Oct 30;5:e3914. doi: 10.7717/peerj.3914. eCollection 2017.

45.

Pharmacoproteomic characterisation of human colon and rectal cancer.

Frejno M, Zenezini Chiozzi R, Wilhelm M, Koch H, Zheng R, Klaeger S, Ruprecht B, Meng C, Kramer K, Jarzab A, Heinzlmeir S, Johnstone E, Domingo E, Kerr D, Jesinghaus M, Slotta-Huspenina J, Weichert W, Knapp S, Feller SM, Kuster B.

Mol Syst Biol. 2017 Nov 3;13(11):951. doi: 10.15252/msb.20177701.

46.

Dietary Compound Resveratrol Is a Pan-BET Bromodomain Inhibitor.

Dutra LA, Heidenreich D, Silva GDBD, Man Chin C, Knapp S, Santos JLD.

Nutrients. 2017 Oct 27;9(11). pii: E1172. doi: 10.3390/nu9111172.

47.

The Shenzhen Declaration on Plant Sciences: Too late or just in time?

Kress WJ, Knapp S.

PhytoKeys. 2017 Sep 18;(86):1-2. doi: 10.3897/phytokeys.86.20712. eCollection 2017. No abstract available.

48.

A revision of the Solanum elaeagnifolium clade (Elaeagnifolium clade; subgenus Leptostemonum, Solanaceae).

Knapp S, Sagona E, Carbonell AKZ, Chiarini F.

PhytoKeys. 2017 Aug 7;(84):1-104. doi: 10.3897/phytokeys.84.12695. eCollection 2017.

49.

The Cysteinome of Protein Kinases as a Target in Drug Development.

Chaikuad A, Koch P, Laufer SA, Knapp S.

Angew Chem Int Ed Engl. 2018 Apr 9;57(16):4372-4385. doi: 10.1002/anie.201707875. Epub 2018 Feb 2. Review.

PMID:
28994500
50.

Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14.

Schuller M, Riedel K, Gibbs-Seymour I, Uth K, Sieg C, Gehring AP, Ahel I, Bracher F, Kessler BM, Elkins JM, Knapp S.

ACS Chem Biol. 2017 Nov 17;12(11):2866-2874. doi: 10.1021/acschembio.7b00445. Epub 2017 Oct 19.

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