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Items: 40

1.

Possibilities and limitations of three-dimensional reconstruction and simulation techniques to identify patterns, rhythms and functions of apoptosis in the early developing neural tube.

Washausen S, Scheffel T, Brunnett G, Knabe W.

Hist Philos Life Sci. 2018 Aug 29;40(3):55. doi: 10.1007/s40656-018-0222-1.

PMID:
30159859
2.

Lateral line placodes of aquatic vertebrates are evolutionarily conserved in mammals.

Washausen S, Knabe W.

Biol Open. 2018 Jun 19;7(6). pii: bio031815. doi: 10.1242/bio.031815.

3.

Neural Progenitors in the Developing Neocortex of the Northern Tree Shrew (Tupaia belangeri) Show a Closer Relationship to Gyrencephalic Primates Than to Lissencephalic Rodents.

Römer S, Bender H, Knabe W, Zimmermann E, Rübsamen R, Seeger J, Fietz SA.

Front Neuroanat. 2018 Apr 19;12:29. doi: 10.3389/fnana.2018.00029. eCollection 2018.

4.

Small Molecules Engage Hot Spots through Cooperative Binding To Inhibit a Tight Protein-Protein Interaction.

Liu D, Xu D, Liu M, Knabe WE, Yuan C, Zhou D, Huang M, Meroueh SO.

Biochemistry. 2017 Mar 28;56(12):1768-1784. doi: 10.1021/acs.biochem.6b01039. Epub 2017 Mar 17.

5.

Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice.

Washausen S, Knabe W.

Brain Struct Funct. 2017 Aug;222(6):2671-2695. doi: 10.1007/s00429-016-1364-0. Epub 2017 Feb 3.

PMID:
28160066
6.

Sex selection of sperm in farm animals: status report and developmental prospects.

Rath D, Barcikowski S, de Graaf S, Garrels W, Grossfeld R, Klein S, Knabe W, Knorr C, Kues W, Meyer H, Michl J, Moench-Tegeder G, Rehbock C, Taylor U, Washausen S.

Reproduction. 2015 Mar;149(3):X1. doi: 10.1530/REP-12-0151e. No abstract available.

PMID:
25680787
7.

A new class of orthosteric uPAR·uPA small-molecule antagonists are allosteric inhibitors of the uPAR·vitronectin interaction.

Liu D, Zhou D, Wang B, Knabe WE, Meroueh SO.

ACS Chem Biol. 2015 Jun 19;10(6):1521-34. doi: 10.1021/cb500832q. Epub 2015 Mar 31.

8.

Discovery and characterization of small molecules that target the GTPase Ral.

Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D.

Nature. 2014 Nov 20;515(7527):443-7. doi: 10.1038/nature13713. Epub 2014 Sep 14.

9.

Probing binding and cellular activity of pyrrolidinone and piperidinone small molecules targeting the urokinase receptor.

Mani T, Liu D, Zhou D, Li L, Knabe WE, Wang F, Oh K, Meroueh SO.

ChemMedChem. 2013 Dec;8(12):1963-77. doi: 10.1002/cmdc.201300340. Epub 2013 Oct 2.

10.

Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis.

Mani T, Wang F, Knabe WE, Sinn AL, Khanna M, Jo I, Sandusky GE, Sledge GW Jr, Jones DR, Khanna R, Pollok KE, Meroueh SO.

Bioorg Med Chem. 2013 Apr 1;21(7):2145-55. doi: 10.1016/j.bmc.2012.12.047. Epub 2013 Jan 9.

11.

Sex selection of sperm in farm animals: status report and developmental prospects.

Rath D, Barcikowski S, de Graaf S, Garrels W, Grossfeld R, Klein S, Knabe W, Knorr C, Kues W, Meyer H, Michl J, Moench-Tegeder G, Rehbock C, Taylor U, Washausen S.

Reproduction. 2013 Jan 8;145(1):R15-30. doi: 10.1530/REP-12-0151. Print 2013 Jan. Review. Erratum in: Reproduction. 2015 Mar;149(3):X1.

PMID:
23148085
12.

Apoptosis contributes to placode morphogenesis in the posterior placodal area of mice.

Washausen S, Knabe W.

Brain Struct Funct. 2013 May;218(3):789-803. doi: 10.1007/s00429-012-0429-y. Epub 2012 May 29.

PMID:
22644920
13.

Targeting multiple conformations leads to small molecule inhibitors of the uPAR·uPA protein-protein interaction that block cancer cell invasion.

Khanna M, Wang F, Jo I, Knabe WE, Wilson SM, Li L, Bum-Erdene K, Li J, W Sledge G, Khanna R, Meroueh SO.

ACS Chem Biol. 2011 Nov 18;6(11):1232-43. doi: 10.1021/cb200180m. Epub 2011 Sep 29.

14.

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.

Wang F, Li J, Sinn AL, Knabe WE, Khanna M, Jo I, Silver JM, Oh K, Li L, Sandusky GE, Sledge GW, Nakshatri H, Jones DR, Pollok KE, Meroueh SO.

J Med Chem. 2011 Oct 27;54(20):7193-205. doi: 10.1021/jm200782y. Epub 2011 Oct 4.

15.

Apoptosis and proliferation in the trigeminal placode.

Knabe W, Obermayer B, Kuhn HJ, Brunnett G, Washausen S.

Brain Struct Funct. 2009 Dec;214(1):49-65. doi: 10.1007/s00429-009-0228-2. Epub 2009 Nov 14.

16.

Reversal of enantioselectivity between the copper(I)- and silver(I)-catalyzed 1,3-dipolar cycloaddition reactions using a brucine-derived amino alcohol ligand.

Kim HY, Shih HJ, Knabe WE, Oh K.

Angew Chem Int Ed Engl. 2009;48(40):7420-3. doi: 10.1002/anie.200903479. No abstract available.

PMID:
19728354
17.

Diversity in mammalian chiasmatic architecture: ipsilateral axons are deflected at glial arches in the prechiasmatic optic nerve of the eutherian Tupaia belangeri.

Knabe W, Washausen S, Happel N, Kuhn HJ.

J Comp Neurol. 2008 May 20;508(3):437-57. doi: 10.1002/cne.21694.

PMID:
18335540
18.

Development of starburst cholinergic amacrine cells in the retina of Tupaia belangeri.

Knabe W, Washausen S, Happel N, Kuhn HJ.

J Comp Neurol. 2007 Jun 1;502(4):584-97.

PMID:
17394160
19.

Expression patterns of erythropoietin and its receptor in the developing spinal cord and dorsal root ganglia.

Knabe W, Sirén AL, Ehrenreich H, Kuhn HJ.

Anat Embryol (Berl). 2005 Oct;210(3):209-19. Epub 2005 Oct 18.

PMID:
16151855
20.

Apoptosis and proliferation in developing, mature, and regressing epibranchial placodes.

Washausen S, Obermayer B, Brunnett G, Kuhn HJ, Knabe W.

Dev Biol. 2005 Feb 1;278(1):86-102.

21.

Endothelin B receptor deficient transgenic rescue rats: a rescue phenomenon in the brain.

Riechers CC, Knabe W, Sirén AL, Gariepy CE, Yanagisawa M, Ehrenreich H.

Neuroscience. 2004;124(4):719-23.

PMID:
15026112
22.

Rhombomere-specific patterns of apoptosis in the tree shrew Tupaia belangeri.

Knabe W, Washausen S, Brunnett G, Kuhn HJ.

Cell Tissue Res. 2004 Apr;316(1):1-13. Epub 2004 Feb 24.

PMID:
14986099
23.

Expression patterns of erythropoietin and its receptor in the developing midbrain.

Knabe W, Knerlich F, Washausen S, Kietzmann T, Sirén AL, Brunnett G, Kuhn HJ, Ehrenreich H.

Anat Embryol (Berl). 2004 Mar;207(6):503-12. Epub 2004 Feb 10.

PMID:
14770308
24.
25.

Calretinin immunoreactivity in the prenatally developing olfactory systems of the tree shrew Tupaia belangeri.

Malz CR, Knabe W, Kuhn HJ.

Anat Embryol (Berl). 2002 May;205(2):83-97. Epub 2002 Apr 19.

PMID:
12021911
26.

High resolution scanning and three-dimensional reconstruction of cellular events in large objects during brain development.

Süss M, Washausen S, Kuhn HJ, Knabe W.

J Neurosci Methods. 2002 Jan 30;113(2):147-58.

PMID:
11772436
27.

Hypoxia and hypoxia-inducible factor modulated gene expression in brain: involvement in neuroprotection and cell death.

Kietzmann T, Knabe W, Schmidt-Kastner R.

Eur Arch Psychiatry Clin Neurosci. 2001 Aug;251(4):170-8. Review.

PMID:
11697581
29.
30.
31.

The patterns of cell death and of macrophages in the developing forebrain of the tree shrew Tupaia belangeri.

Knabe W, Süss M, Kuhn HJ.

Anat Embryol (Berl). 2000 Mar;201(3):157-68.

PMID:
10664177
32.

Horizontal cells invest retinal capillaries in the tree shrew Tupaia belangeri.

Knabe W, Ochs M.

Cell Tissue Res. 1999 Oct;298(1):33-43.

PMID:
10555537
33.
34.

Pattern of cell death during optic cup formation in the tree shrew Tupaia belangeri.

Knabe W, Kuhn HJ.

J Comp Neurol. 1998 Nov 23;401(3):352-66.

PMID:
9811113
35.

Disk formation in retinal cones of Tupaia belangeri (Scandentia).

Knabe W, Kuhn H.

Cell Tissue Res. 1998 Apr;292(1):67-76.

PMID:
9506913
36.

Ciliogenesis in photoreceptor cells of the tree shrew retina.

Knabe W, Kuhn HJ.

Anat Embryol (Berl). 1997 Aug;196(2):123-31.

PMID:
9278157
37.

"Lens mitochondria" in the retinal cones of the tree-shrew Tupaia belangeri.

Knabe W, Skatchkov S, Kuhn HJ.

Vision Res. 1997 Feb;37(3):267-71.

38.
39.
40.

Low-gravity environment in Spacelab.

Knabe W, Eilers D.

Acta Astronaut. 1982 Apr;9(4):187-98.

PMID:
11541689

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