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Items: 1 to 50 of 94

1.

Filaments and phenotypes: cellular roles and orphan effects associated with mutations in cytoplasmic intermediate filament proteins.

Klymkowsky MW.

F1000Res. 2019 Sep 30;8. pii: F1000 Faculty Rev-1703. doi: 10.12688/f1000research.19950.1. eCollection 2019. Review.

2.

Whole-Mount Immunocytochemistry in Xenopus.

Klymkowsky MW.

Cold Spring Harb Protoc. 2018 Jan 2;2018(1). doi: 10.1101/pdb.prot097295.

PMID:
29192091
3.

TSPAN12 Is a Norrin Co-receptor that Amplifies Frizzled4 Ligand Selectivity and Signaling.

Lai MB, Zhang C, Shi J, Johnson V, Khandan L, McVey J, Klymkowsky MW, Chen Z, Junge HJ.

Cell Rep. 2017 Jun 27;19(13):2809-2822. doi: 10.1016/j.celrep.2017.06.004.

4.

Nuclear roles for cilia-associated proteins.

McClure-Begley TD, Klymkowsky MW.

Cilia. 2017 May 25;6:8. doi: 10.1186/s13630-017-0052-x. eCollection 2017. Review.

5.

Diagnostic of students' misconceptions using the Biological Concepts Instrument (BCI): A method for conducting an educational needs assessment.

Champagne Queloz A, Klymkowsky MW, Stern E, Hafen E, Köhler K.

PLoS One. 2017 May 11;12(5):e0176906. doi: 10.1371/journal.pone.0176906. eCollection 2017.

6.

The Design and Transformation of Biofundamentals: A Nonsurvey Introductory Evolutionary and Molecular Biology Course.

Klymkowsky MW, Rentsch JD, Begovic E, Cooper MM.

CBE Life Sci Educ. 2016 winter;15(4). pii: ar70.

7.

Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling.

Zhao Y, Shi J, Winey M, Klymkowsky MW.

Dev Biol. 2016 Mar 15;411(2):257-265. doi: 10.1016/j.ydbio.2016.01.004. Epub 2016 Jan 16.

8.

CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates.

Square T, Romášek M, Jandzik D, Cattell MV, Klymkowsky M, Medeiros DM.

Development. 2015 Dec 1;142(23):4180-7. doi: 10.1242/dev.125609. Epub 2015 Oct 28.

9.

Centrin-2 (Cetn2) mediated regulation of FGF/FGFR gene expression in Xenopus.

Shi J, Zhao Y, Vonderfecht T, Winey M, Klymkowsky MW.

Sci Rep. 2015 May 27;5:10283. doi: 10.1038/srep10283.

10.

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.

Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW.

Dev Biol. 2014 Nov 15;395(2):287-98. doi: 10.1016/j.ydbio.2014.09.008. Epub 2014 Sep 16.

11.

The trouble with chemical energy: why understanding bond energies requires an interdisciplinary systems approach.

Cooper MM, Klymkowsky MW.

CBE Life Sci Educ. 2013 Jun 1;12(2):306-12. doi: 10.1187/cbe.12-10-0170.

12.

Turning randomness into meaning at the molecular level using Muller's morphs.

Henson K, Cooper MM, Klymkowsky MW.

Biol Open. 2012 Apr 15;1(4):405-10. doi: 10.1242/bio.2012031. Epub 2012 Feb 27.

13.

sizzled function and secreted factor network dynamics.

Shi J, Zhang H, Dowell RD, Klymkowsky MW.

Biol Open. 2012 Mar 15;1(3):286-94. doi: 10.1242/bio.2012019. Epub 2012 Feb 3.

14.

A maternally established SoxB1/SoxF axis is a conserved feature of chordate germ layer patterning.

Cattell MV, Garnett AT, Klymkowsky MW, Medeiros DM.

Evol Dev. 2012 Jan-Feb;14(1):104-15. doi: 10.1111/j.1525-142X.2011.00525.x.

PMID:
23016978
15.

Now for the hard part: the path to coherent curricular design.

Klymkowsky MW, Cooper MM.

Biochem Mol Biol Educ. 2012 Jul;40(4):271-2. doi: 10.1002/bmb.20614. Epub 2012 Jun 18. No abstract available.

16.

Using graph-based assessments within socratic tutorials to reveal and refine students' analytical thinking about molecular networks.

Trujillo C, Cooper MM, Klymkowsky MW.

Biochem Mol Biol Educ. 2012 Mar-Apr;40(2):100-7. doi: 10.1002/bmb.20585. Epub 2012 Feb 28.

17.

Snail2 controls mesodermal BMP/Wnt induction of neural crest.

Shi J, Severson C, Yang J, Wedlich D, Klymkowsky MW.

Development. 2011 Aug;138(15):3135-45. doi: 10.1242/dev.064394. Epub 2011 Jun 29.

18.

Mitochondrial activity, embryogenesis, and the dialogue between the big and little brains of the cell.

Klymkowsky MW.

Mitochondrion. 2011 Sep;11(5):814-9. doi: 10.1016/j.mito.2010.11.002. Epub 2010 Dec 4. Review.

PMID:
21134489
19.

Thinking about the conceptual foundations of the biological sciences.

Klymkowsky MW.

CBE Life Sci Educ. 2010 Winter;9(4):405-7. doi: 10.1187/cbe.10-04-0061.

20.

Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis.

Klymkowsky MW, Rossi CC, Artinger KB.

Cell Adh Migr. 2010 Oct-Dec;4(4):595-608. Review.

21.

Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification.

Hikasa H, Ezan J, Itoh K, Li X, Klymkowsky MW, Sokol SY.

Dev Cell. 2010 Oct 19;19(4):521-32. doi: 10.1016/j.devcel.2010.09.005.

22.

Make room for computing.

Klymkowsky MW.

Science. 2009 Oct 9;326(5950):227. doi: 10.1126/science.326_227b. No abstract available.

PMID:
19815753
23.

Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus.

Zhang C, Klymkowsky MW.

Dev Biol. 2009 Jul 15;331(2):340-9. doi: 10.1016/j.ydbio.2009.04.016. Epub 2009 Apr 21.

24.

Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe.

Klymkowsky MW, Savagner P.

Am J Pathol. 2009 May;174(5):1588-93. doi: 10.2353/ajpath.2009.080545. Epub 2009 Mar 26. Review.

25.

Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion.

Schlosser G, Awtry T, Brugmann SA, Jensen ED, Neilson K, Ruan G, Stammler A, Voelker D, Yan B, Zhang C, Klymkowsky MW, Moody SA.

Dev Biol. 2008 Aug 1;320(1):199-214. doi: 10.1016/j.ydbio.2008.05.523. Epub 2008 May 20.

26.

Understanding randomness and its impact on student learning: lessons learned from building the Biology Concept Inventory (BCI).

Garvin-Doxas K, Klymkowsky MW.

CBE Life Sci Educ. 2008 Summer;7(2):227-33. doi: 10.1187/cbe.07-08-0063.

27.

Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis.

Rossi CC, Hernandez-Lagunas L, Zhang C, Choi IF, Kwok L, Klymkowsky M, Artinger KB.

Dev Biol. 2008 Feb 15;314(2):351-61. doi: 10.1016/j.ydbio.2007.11.036. Epub 2007 Dec 8.

28.

Recognizing student misconceptions through Ed's Tools and the Biology Concept Inventory.

Klymkowsky MW, Garvin-Doxas K.

PLoS Biol. 2008 Jan;6(1):e3. doi: 10.1371/journal.pbio.0060003. No abstract available.

30.
31.

The Sox axis, Nodal signaling, and germ layer specification.

Zhang C, Klymkowsky MW.

Differentiation. 2007 Jul;75(6):536-45. Epub 2007 Jul 2.

PMID:
17608734
32.

An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm.

Zhang C, Carl TF, Trudeau ED, Simmet T, Klymkowsky MW.

PLoS One. 2006 Dec 27;1:e106.

33.

Sox3 expression identifies neural progenitors in persistent neonatal and adult mouse forebrain germinative zones.

Wang TW, Stromberg GP, Whitney JT, Brower NW, Klymkowsky MW, Parent JM.

J Comp Neurol. 2006 Jul 1;497(1):88-100.

34.
35.

SOX7 and SOX18 are essential for cardiogenesis in Xenopus.

Zhang C, Basta T, Klymkowsky MW.

Dev Dyn. 2005 Dec;234(4):878-91.

36.

beta-catenin and its regulatory network.

Klymkowsky MW.

Hum Pathol. 2005 Mar;36(3):225-7. Review. No abstract available.

PMID:
15791565
37.

SOX7 is an immediate-early target of VegT and regulates Nodal-related gene expression in Xenopus.

Zhang C, Basta T, Fawcett SR, Klymkowsky MW.

Dev Biol. 2005 Feb 15;278(2):526-41.

38.

Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish.

Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple DL, Artinger KB, Klymkowsky MW.

Dev Biol. 2004 Sep 1;273(1):23-37.

39.

Embryonic expression of Xenopus laevis SOX7.

Fawcett SR, Klymkowsky MW.

Gene Expr Patterns. 2004 Jan;4(1):29-33.

PMID:
14678825
40.

The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation.

Zhang C, Basta T, Jensen ED, Klymkowsky MW.

Development. 2003 Dec;130(23):5609-24. Epub 2003 Oct 1.

41.

Bioliteracy and teaching efficacy: what biologists can learn from physicists.

Klymkowsky MW, Garvin-Doxas K, Zeilik M.

Cell Biol Educ. 2003 Fall;2(3):155-61.

42.

Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes.

Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW.

Cell Motil Cytoskeleton. 2003 Feb;54(2):105-21.

PMID:
12529857
43.

Limb development in a "nonmodel" vertebrate, the direct-developing frog Eleutherodactylus coqui.

Hanken J, Carl TF, Richardson MK, Olsson L, Schlosser G, Osabutey CK, Klymkowsky MW.

J Exp Zool. 2001 Dec 15;291(4):375-88.

PMID:
11754016
44.

Paranemin and the organization of desmin filament networks.

Schweitzer SC, Klymkowsky MW, Bellin RM, Robson RM, Capetanaki Y, Evans RM.

J Cell Sci. 2001 Mar;114(Pt 6):1079-89.

45.

Cadherins and catenins, Wnts and SOXs: embryonic patterning in Xenopus.

St Amand AL, Klymkowsky MW.

Int Rev Cytol. 2001;203:291-355. Review.

PMID:
11131519
46.

A comparative evaluation of beta-catenin and plakoglobin signaling activity.

Williams BO, Barish GD, Klymkowsky MW, Varmus HE.

Oncogene. 2000 Nov 23;19(50):5720-8.

47.

Weaving a tangled web: the interconnected cytoskeleton.

Klymkowsky MW.

Nat Cell Biol. 1999 Sep;1(5):E121-3. No abstract available.

PMID:
10559951
48.

Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin.

Zorn AM, Barish GD, Williams BO, Lavender P, Klymkowsky MW, Varmus HE.

Mol Cell. 1999 Oct;4(4):487-98.

49.

Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling.

Klymkowsky MW, Williams BO, Barish GD, Varmus HE, Vourgourakis YE.

Mol Biol Cell. 1999 Oct;10(10):3151-69.

50.

Inhibition of neural crest migration in Xenopus using antisense slug RNA.

Carl TF, Dufton C, Hanken J, Klymkowsky MW.

Dev Biol. 1999 Sep 1;213(1):101-15.

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