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Items: 1 to 50 of 126

1.

Simultaneous computer-assisted assessment of mucosal and serosal perfusion in a model of segmental colonic ischemia.

Seeliger B, Agnus V, Mascagni P, Barberio M, Longo F, Lapergola A, Mutter D, Klymchenko AS, Chand M, Marescaux J, Diana M.

Surg Endosc. 2019 Nov 18. doi: 10.1007/s00464-019-07258-z. [Epub ahead of print]

PMID:
31741157
2.

Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.

Buenaventura T, Bitsi S, Laughlin WE, Burgoyne T, Lyu Z, Oqua AI, Norman H, McGlone ER, Klymchenko AS, Corrêa IR Jr, Walker A, Inoue A, Hanyaloglu A, Grimes J, Koszegi Z, Calebiro D, Rutter GA, Bloom SR, Jones B, Tomas A.

PLoS Biol. 2019 Aug 20;17(8):e3000097. doi: 10.1371/journal.pbio.3000097. eCollection 2019 Aug.

3.

Switchable Solvatochromic Probes for Live-Cell Super-resolution Imaging of Plasma Membrane Organization.

Danylchuk DI, Moon S, Xu K, Klymchenko AS.

Angew Chem Int Ed Engl. 2019 Oct 14;58(42):14920-14924. doi: 10.1002/anie.201907690. Epub 2019 Aug 27.

PMID:
31392763
4.

BODIPY-loaded polymer nanoparticles: chemical structure of cargo defines leakage from nanocarrier in living cells.

Trofymchuk K, Valanciunaite J, Andreiuk B, Reisch A, Collot M, Klymchenko AS.

J Mater Chem B. 2019 Aug 28;7(34):5199-5210. doi: 10.1039/c8tb02781a.

PMID:
31364614
5.

S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane.

Jiang M, Hu J, White FKH, Williamson J, Klymchenko AS, Murthy A, Workman SW, Tseng GN.

J Biol Chem. 2019 Sep 6;294(36):13487-13501. doi: 10.1074/jbc.RA118.006772. Epub 2019 Jul 23.

PMID:
31337710
6.

Hybrid fluorescent magnetic gastrojejunostomy: an experimental feasibility study in the porcine model and human cadaver.

Watanabe R, Barberio M, Kanaji S, Lapergola A, Ashoka AH, Andreiuk B, Guerriero L, Pizzicannella M, Seeliger B, Saida Y, Kaneko H, Worreth M, Saadi A, Marescaux J, Klymchenko AS, Diana M.

Surg Endosc. 2019 Jul 17. doi: 10.1007/s00464-019-06963-z. [Epub ahead of print]

PMID:
31317330
7.

Ionic aggregation-induced emission dye with bulky counterions for preparation of bright near-infrared polymeric nanoparticles.

Adarsh N, Klymchenko AS.

Nanoscale. 2019 Aug 7;11(29):13977-13987. doi: 10.1039/c9nr04085d. Epub 2019 Jul 16.

PMID:
31309959
8.

A fluorogenic BODIPY molecular rotor as an apoptosis marker.

Ashokkumar P, Ashoka AH, Collot M, Das A, Klymchenko AS.

Chem Commun (Camb). 2019 Jun 11;55(48):6902-6905. doi: 10.1039/c9cc03242h.

PMID:
31134979
9.

Solvatochromic Near-Infrared Probe for Polarity Mapping of Biomembranes and Lipid Droplets in Cells under Stress.

Ashoka AH, Ashokkumar P, Kovtun YP, Klymchenko AS.

J Phys Chem Lett. 2019 May 16;10(10):2414-2421. doi: 10.1021/acs.jpclett.9b00668. Epub 2019 Apr 30.

PMID:
31021640
10.

Optimizing the Fluorescence Properties of Nanoemulsions for Single Particle Tracking in Live Cells.

Wang X, Anton N, Ashokkumar P, Anton H, Fam TK, Vandamme T, Klymchenko AS, Collot M.

ACS Appl Mater Interfaces. 2019 Apr 10;11(14):13079-13090. doi: 10.1021/acsami.8b22297. Epub 2019 Mar 28.

PMID:
30844230
11.

MemBright: A Family of Fluorescent Membrane Probes for Advanced Cellular Imaging and Neuroscience.

Collot M, Ashokkumar P, Anton H, Boutant E, Faklaris O, Galli T, Mély Y, Danglot L, Klymchenko AS.

Cell Chem Biol. 2019 Apr 18;26(4):600-614.e7. doi: 10.1016/j.chembiol.2019.01.009. Epub 2019 Feb 7.

PMID:
30745238
12.

Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo.

Hyenne V, Ghoroghi S, Collot M, Bons J, Follain G, Harlepp S, Mary B, Bauer J, Mercier L, Busnelli I, Lefebvre O, Fekonja N, Garcia-Leon MJ, Machado P, Delalande F, López AA, Silva SG, Verweij FJ, van Niel G, Djouad F, Peinado H, Carapito C, Klymchenko AS, Goetz JG.

Dev Cell. 2019 Feb 25;48(4):554-572.e7. doi: 10.1016/j.devcel.2019.01.014. Epub 2019 Feb 7.

PMID:
30745140
13.

Fighting Aggregation-Caused Quenching and Leakage of Dyes in Fluorescent Polymer Nanoparticles: Universal Role of Counterion.

Andreiuk B, Reisch A, Bernhardt E, Klymchenko AS.

Chem Asian J. 2019 Mar 15;14(6):836-846. doi: 10.1002/asia.201801592. Epub 2019 Jan 23.

PMID:
30604924
14.

Probing Polarity and Heterogeneity of Lipid Droplets in Live Cells Using a Push-Pull Fluorophore.

Collot M, Bou S, Fam TK, Richert L, Mély Y, Danglot L, Klymchenko AS.

Anal Chem. 2019 Feb 5;91(3):1928-1935. doi: 10.1021/acs.analchem.8b04218. Epub 2019 Jan 11.

PMID:
30592219
15.

BODIPY with Tuned Amphiphilicity as a Fluorogenic Plasma Membrane Probe.

Collot M, Boutant E, Lehmann M, Klymchenko AS.

Bioconjug Chem. 2019 Jan 16;30(1):192-199. doi: 10.1021/acs.bioconjchem.8b00828. Epub 2019 Jan 3.

PMID:
30562000
16.

Quantifying Release from Lipid Nanocarriers by Fluorescence Correlation Spectroscopy.

Bouchaala R, Richert L, Anton N, Vandamme TF, Djabi S, Mély Y, Klymchenko AS.

ACS Omega. 2018 Oct 31;3(10):14333-14340. doi: 10.1021/acsomega.8b01488. Epub 2018 Oct 29.

17.

Recent Advances in Fluorescent Probes for Lipid Droplets.

Fam TK, Klymchenko AS, Collot M.

Materials (Basel). 2018 Sep 18;11(9). pii: E1768. doi: 10.3390/ma11091768. Review.

18.

DNA-Functionalized Dye-Loaded Polymeric Nanoparticles: Ultrabright FRET Platform for Amplified Detection of Nucleic Acids.

Melnychuk N, Klymchenko AS.

J Am Chem Soc. 2018 Aug 29;140(34):10856-10865. doi: 10.1021/jacs.8b05840. Epub 2018 Aug 15.

PMID:
30067022
19.

Apoptosis and eryptosis: Striking differences on biomembrane level.

Pyrshev KA, Klymchenko AS, Csúcs G, Demchenko AP.

Biochim Biophys Acta Biomembr. 2018 Jun;1860(6):1362-1371. doi: 10.1016/j.bbamem.2018.03.019. Epub 2018 Mar 22.

20.

Ultrabright and Fluorogenic Probes for Multicolor Imaging and Tracking of Lipid Droplets in Cells and Tissues.

Collot M, Fam TK, Ashokkumar P, Faklaris O, Galli T, Danglot L, Klymchenko AS.

J Am Chem Soc. 2018 Apr 25;140(16):5401-5411. doi: 10.1021/jacs.7b12817. Epub 2018 Feb 27.

PMID:
29446627
21.

In Vivo FRET Imaging to Predict the Risk Associated with Hepatic Accumulation of Squalene-Based Prodrug Nanoparticles.

Cayre F, Mura S, Andreiuk B, Sobot D, Gouazou S, Desmaële D, Klymchenko AS, Couvreur P.

Adv Healthc Mater. 2018 Feb;7(3). doi: 10.1002/adhm.201700830. Epub 2017 Nov 30.

PMID:
29195020
22.

Tailoring Fluorescence Brightness and Switching of Nanoparticles through Dye Organization in the Polymer Matrix.

Reisch A, Trofymchuk K, Runser A, Fleith G, Rawiso M, Klymchenko AS.

ACS Appl Mater Interfaces. 2017 Dec 13;9(49):43030-43042. doi: 10.1021/acsami.7b12292. Epub 2017 Nov 29.

PMID:
29185702
23.

Turn-on Fluorene Push-Pull Probes with High Brightness and Photostability for Visualizing Lipid Order in Biomembranes.

Shaya J, Collot M, Bénailly F, Mahmoud N, Mély Y, Michel BY, Klymchenko AS, Burger A.

ACS Chem Biol. 2017 Dec 15;12(12):3022-3030. doi: 10.1021/acschembio.7b00658. Epub 2017 Nov 8.

PMID:
29053920
24.

PEGylated Red-Emitting Calcium Probe with Improved Sensing Properties for Neuroscience.

Ponsot F, Shen W, Ashokkumar P, Audinat E, Klymchenko AS, Collot M.

ACS Sens. 2017 Nov 22;2(11):1706-1712. doi: 10.1021/acssensors.7b00665. Epub 2017 Oct 24.

PMID:
29019233
25.

Giant light-harvesting nanoantenna for single-molecule detection in ambient light.

Trofymchuk K, Reisch A, Didier P, Fras F, Gilliot P, Mely Y, Klymchenko AS.

Nat Photonics. 2017 Oct;11(10):657-663. doi: 10.1038/s41566-017-0001-7. Epub 2017 Sep 29.

26.

Fluorescent Polymer Nanoparticles for Cell Barcoding In Vitro and In Vivo.

Andreiuk B, Reisch A, Lindecker M, Follain G, Peyriéras N, Goetz JG, Klymchenko AS.

Small. 2017 Oct;13(38). doi: 10.1002/smll.201701582. Epub 2017 Aug 9.

PMID:
28791769
27.

Caspase-3 activation decreases lipid order in the outer plasma membrane leaflet during apoptosis: A fluorescent probe study.

Pyrshev KA, Yesylevskyy SO, Mély Y, Demchenko AP, Klymchenko AS.

Biochim Biophys Acta Biomembr. 2017 Oct;1859(10):2123-2132. doi: 10.1016/j.bbamem.2017.08.002. Epub 2017 Aug 5.

28.

Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.

Sezgin E, Schneider F, Zilles V, Urbančič I, Garcia E, Waithe D, Klymchenko AS, Eggeling C.

Biophys J. 2017 Sep 19;113(6):1321-1330. doi: 10.1016/j.bpj.2017.06.050. Epub 2017 Jul 19.

29.

A Toolbox of Chromones and Quinolones for Measuring a Wide Range of ATP Concentrations.

Pivovarenko VG, Bugera O, Humbert N, Klymchenko AS, Mély Y.

Chemistry. 2017 Sep 4;23(49):11927-11934. doi: 10.1002/chem.201702484. Epub 2017 Aug 9.

PMID:
28708306
30.

Visualising the membrane viscosity of porcine eye lens cells using molecular rotors.

Sherin PS, López-Duarte I, Dent MR, Kubánková M, Vyšniauskas A, Bull JA, Reshetnikova ES, Klymchenko AS, Tsentalovich YP, Kuimova MK.

Chem Sci. 2017 May 1;8(5):3523-3528. doi: 10.1039/c6sc05369f. Epub 2017 Feb 14.

31.

Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery.

Sobot D, Mura S, Yesylevskyy SO, Dalbin L, Cayre F, Bort G, Mougin J, Desmaële D, Lepetre-Mouelhi S, Pieters G, Andreiuk B, Klymchenko AS, Paul JL, Ramseyer C, Couvreur P.

Nat Commun. 2017 May 30;8:15678. doi: 10.1038/ncomms15678.

32.

Light-triggered release from dye-loaded fluorescent lipid nanocarriers in vitro and in vivo.

Bouchaala R, Anton N, Anton H, Vandamme T, Vermot J, Smail D, Mély Y, Klymchenko AS.

Colloids Surf B Biointerfaces. 2017 Aug 1;156:414-421. doi: 10.1016/j.colsurfb.2017.05.035. Epub 2017 May 15.

PMID:
28551576
33.

Ca-NIR: a ratiometric near-infrared calcium probe based on a dihydroxanthene-hemicyanine fluorophore.

Collot M, Ponsot F, Klymchenko AS.

Chem Commun (Camb). 2017 Jun 1;53(45):6117-6120. doi: 10.1039/c7cc02418e.

PMID:
28530289
34.

Push-pull dioxaborine as fluorescent molecular rotor: far-red fluorogenic probe for ligand-receptor interactions.

Karpenko IA, Niko Y, Yakubovskyi VP, Gerasov AO, Bonnet D, Kovtun YP, Klymchenko AS.

J Mater Chem C Mater. 2016 Apr 14;4(14):3002-3009. doi: 10.1039/C5TC03411F. Epub 2015 Dec 7.

35.

Functionalizing Nanoemulsions with Carboxylates: Impact on the Biodistribution and Pharmacokinetics in Mice.

Attia MF, Dieng SM, Collot M, Klymchenko AS, Bouillot C, Serra CA, Schmutz M, Er-Rafik M, Vandamme TF, Anton N.

Macromol Biosci. 2017 Jul;17(7). doi: 10.1002/mabi.201600471. Epub 2017 Mar 17.

PMID:
28306222
36.

Lipid nanocapsules maintain full integrity after crossing a human intestinal epithelium model.

Roger E, Gimel JC, Bensley C, Klymchenko AS, Benoit JP.

J Control Release. 2017 May 10;253:11-18. doi: 10.1016/j.jconrel.2017.03.005. Epub 2017 Mar 6.

PMID:
28274740
37.

Solvatochromic and Fluorogenic Dyes as Environment-Sensitive Probes: Design and Biological Applications.

Klymchenko AS.

Acc Chem Res. 2017 Feb 21;50(2):366-375. doi: 10.1021/acs.accounts.6b00517. Epub 2017 Jan 9.

PMID:
28067047
38.

Protein-Sized Bright Fluorogenic Nanoparticles Based on Cross-Linked Calixarene Micelles with Cyanine Corona.

Shulov I, Rodik RV, Arntz Y, Reisch A, Kalchenko VI, Klymchenko AS.

Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15884-15888. doi: 10.1002/anie.201609138. Epub 2016 Nov 16.

39.

Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice.

Bouchaala R, Mercier L, Andreiuk B, Mély Y, Vandamme T, Anton N, Goetz JG, Klymchenko AS.

J Control Release. 2016 Aug 28;236:57-67. doi: 10.1016/j.jconrel.2016.06.027. Epub 2016 Jun 17.

40.

Non-coordinating anions assemble cyanine amphiphiles into ultra-small fluorescent nanoparticles.

Shulov I, Arntz Y, Mély Y, Pivovarenko VG, Klymchenko AS.

Chem Commun (Camb). 2016 Jun 28;52(51):7962-5. doi: 10.1039/c6cc03716j. Epub 2016 Jun 2.

PMID:
27251475
41.

Labeling nanoparticles: Dye leakage and altered cellular uptake.

Snipstad S, Hak S, Baghirov H, Sulheim E, Mørch Ý, Lélu S, von Haartman E, Bäck M, Nilsson KPR, Klymchenko AS, de Lange Davies C, Åslund AKO.

Cytometry A. 2017 Aug;91(8):760-766. doi: 10.1002/cyto.a.22853. Epub 2016 Apr 14.

42.

Fluorescent Polymer Nanoparticles Based on Dyes: Seeking Brighter Tools for Bioimaging.

Reisch A, Klymchenko AS.

Small. 2016 Apr;12(15):1968-92. doi: 10.1002/smll.201503396. Epub 2016 Feb 22. Review.

43.

Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes.

Niko Y, Didier P, Mely Y, Konishi G, Klymchenko AS.

Sci Rep. 2016 Jan 11;6:18870. doi: 10.1038/srep18870.

44.

Inter-nanocarrier and nanocarrier-to-cell transfer assays demonstrate the risk of an immediate unloading of dye from labeled lipid nanocapsules.

Simonsson C, Bastiat G, Pitorre M, Klymchenko AS, Béjaud J, Mély Y, Benoit JP.

Eur J Pharm Biopharm. 2016 Jan;98:47-56. doi: 10.1016/j.ejpb.2015.10.011. Epub 2015 Oct 30.

PMID:
26522878
45.

Fluorinated counterion-enhanced emission of rhodamine aggregates: ultrabright nanoparticles for bioimaging and light-harvesting.

Shulov I, Oncul S, Reisch A, Arntz Y, Collot M, Mely Y, Klymchenko AS.

Nanoscale. 2015 Nov 21;7(43):18198-210. doi: 10.1039/c5nr04955e.

PMID:
26482443
46.

Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum.

Collot M, Kreder R, Tatarets AL, Patsenker LD, Mely Y, Klymchenko AS.

Chem Commun (Camb). 2015 Dec 14;51(96):17136-9. doi: 10.1039/c5cc06094j.

PMID:
26455447
47.

Exploiting Fast Exciton Diffusion in Dye-Doped Polymer Nanoparticles to Engineer Efficient Photoswitching.

Trofymchuk K, Prodi L, Reisch A, Mély Y, Altenhöner K, Mattay J, Klymchenko AS.

J Phys Chem Lett. 2015 Jun 18;6(12):2259-64. doi: 10.1021/acs.jpclett.5b00769. Epub 2015 Jun 3.

PMID:
26266601
48.

Microfluidic conceived Trojan microcarriers for oral delivery of nanoparticles.

Khan IU, Serra CA, Anton N, Er-Rafik M, Blanck C, Schmutz M, Kraus I, Messaddeq N, Sutter C, Anton H, Klymchenko AS, Vandamme TF.

Int J Pharm. 2015 Sep 30;493(1-2):7-15. doi: 10.1016/j.ijpharm.2015.06.028. Epub 2015 Jun 23.

PMID:
26116014
49.

Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties.

Neuberg P, Perino A, Morin-Picardat E, Anton N, Darwich Z, Weltin D, Mely Y, Klymchenko AS, Remy JS, Wagner A.

Chem Commun (Camb). 2015 Jul 25;51(58):11595-8. doi: 10.1039/c5cc03820k. Epub 2015 Jun 22.

PMID:
26095460
50.

Charge-controlled nanoprecipitation as a modular approach to ultrasmall polymer nanocarriers: making bright and stable nanoparticles.

Reisch A, Runser A, Arntz Y, Mély Y, Klymchenko AS.

ACS Nano. 2015 May 26;9(5):5104-16. doi: 10.1021/acsnano.5b00214. Epub 2015 Apr 27.

PMID:
25894117

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