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Items: 21

1.

Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database.

Kluxen FM, Grégoire S, Schepky A, Hewitt NJ, Klaric M, Domoradzki JY, Felkers E, Fernandes J, Fisher P, McEuen SF, Parr-Dobrzanski R, Wiemann C.

Regul Toxicol Pharmacol. 2019 Nov;108:104475. doi: 10.1016/j.yrtph.2019.104475. Epub 2019 Sep 17.

2.

Scatter plotting as a simple tool to analyse relative organ to body weight in toxicological bioassays.

Kluxen FM.

Arch Toxicol. 2019 Aug;93(8):2409-2420. doi: 10.1007/s00204-019-02509-3. Epub 2019 Jul 1.

PMID:
31263913
3.

A Review of Recent Advances in Benchmark Dose Methodology.

Jensen SM, Kluxen FM, Ritz C.

Risk Anal. 2019 Oct;39(10):2295-2315. doi: 10.1111/risa.13324. Epub 2019 May 2.

PMID:
31046141
4.

Assessing in vitro dermal absorption of dry residues of agrochemical sprays using human skin within OECD TG 428.

Aggarwal M, Fisher P, Kluxen FM, Maas W, Morgan N, Parr-Dobrzanski R, Strupp C, Wiemann C.

Regul Toxicol Pharmacol. 2019 Aug;106:55-67. doi: 10.1016/j.yrtph.2019.04.016. Epub 2019 Apr 25.

5.

Lifelong exposure to dietary isoflavones reduces risk of obesity in ovariectomized Wistar rats.

Kurrat A, Blei T, Kluxen FM, Mueller DR, Piechotta M, Soukup ST, Kulling SE, Diel P.

Mol Nutr Food Res. 2015 Dec;59(12):2407-18. doi: 10.1002/mnfr.201500240. Epub 2015 Sep 30.

PMID:
26346629
6.

Assessment of an extended dataset of in vitro human dermal absorption studies on pesticides to determine default values, opportunities for read-across and influence of dilution on absorption.

Aggarwal M, Fisher P, Hüser A, Kluxen FM, Parr-Dobrzanski R, Soufi M, Strupp C, Wiemann C, Billington R.

Regul Toxicol Pharmacol. 2015 Jun;72(1):58-70. doi: 10.1016/j.yrtph.2015.02.017. Epub 2015 Mar 9.

7.

Genistein modulates the anti-tumor activity of cisplatin in MCF-7 breast and HT-29 colon cancer cells.

Hu XJ, Xie MY, Kluxen FM, Diel P.

Arch Toxicol. 2014 Mar;88(3):625-35. doi: 10.1007/s00204-013-1184-4. Epub 2014 Feb 7.

PMID:
24504162
8.

Molecular effects of ER alpha- and beta-selective agonists on regulation of energy homeostasis in obese female Wistar rats.

Weigt C, Hertrampf T, Kluxen FM, Flenker U, Hülsemann F, Fritzemeier KH, Diel P.

Mol Cell Endocrinol. 2013 Sep 5;377(1-2):147-58. doi: 10.1016/j.mce.2013.07.007. Epub 2013 Jul 19.

PMID:
23871901
9.

The metallohormone cadmium modulates AhR-associated gene expression in the small intestine of rats similar to ethinyl-estradiol.

Kluxen FM, Diel P, Höfer N, Becker E, Degen GH.

Arch Toxicol. 2013 Apr;87(4):633-43. doi: 10.1007/s00204-012-0971-7. Epub 2012 Nov 8.

PMID:
23135549
10.

Cadmium modulates expression of aryl hydrocarbon receptor-associated genes in rat uterus by interaction with the estrogen receptor.

Kluxen FM, Höfer N, Kretzschmar G, Degen GH, Diel P.

Arch Toxicol. 2012 Apr;86(4):591-601. doi: 10.1007/s00204-011-0787-x. Epub 2011 Nov 30.

PMID:
22127542
11.

ERβ-specific agonists and genistein inhibit proliferation and induce apoptosis in the large and small intestine.

Schleipen B, Hertrampf T, Fritzemeier KH, Kluxen FM, Lorenz A, Molzberger A, Velders M, Diel P.

Carcinogenesis. 2011 Nov;32(11):1675-83. doi: 10.1093/carcin/bgr188. Epub 2011 Aug 19.

PMID:
21856997
12.

Investigations on the estrogenic activity of the metallohormone cadmium in the rat intestine.

Höfer N, Diel P, Wittsiepe J, Wilhelm M, Kluxen FM, Degen GH.

Arch Toxicol. 2010 Jul;84(7):541-52. doi: 10.1007/s00204-010-0524-x. Epub 2010 Feb 26.

PMID:
20186393
13.

Late ischemic preconditioning of the myocardium alters the expression of genes involved in inflammatory response.

Zubakov D, Hoheisel JD, Kluxen FW, Brändle M, Ehring T, Hentsch B, Frohme M.

FEBS Lett. 2003 Jul 17;547(1-3):51-5.

14.

Cardiac ankyrin repeat protein, a negative regulator of cardiac gene expression, is augmented in human heart failure.

Zolk O, Frohme M, Maurer A, Kluxen FW, Hentsch B, Zubakov D, Hoheisel JD, Zucker IH, Pepe S, Eschenhagen T.

Biochem Biophys Res Commun. 2002 May 24;293(5):1377-82.

PMID:
12054667
15.
16.

Molecular cloning and expression of a novel type V adenylyl cyclase from rabbit myocardium.

Wallach J, Droste M, Kluxen FW, Pfeuffer T, Frank R.

FEBS Lett. 1994 Feb 7;338(3):257-63.

17.

Maximal expression of recombinant cDNAs in COS cells for use in expression cloning.

Kluxen FW, Lübbert H.

Anal Biochem. 1993 Feb 1;208(2):352-6.

PMID:
8452232
18.

Cloning and functional characterization of the rat stomach fundus serotonin receptor.

Foguet M, Hoyer D, Pardo LA, Parekh A, Kluxen FW, Kalkman HO, Stühmer W, Lübbert H.

EMBO J. 1992 Sep;11(9):3481-7.

19.

Expression cloning of a rat brain somatostatin receptor cDNA.

Kluxen FW, Bruns C, Lübbert H.

Proc Natl Acad Sci U S A. 1992 May 15;89(10):4618-22.

20.

Opposite regulation of the mRNAs for parvalbumin and p19/6.8 in myotonic mouse muscle.

Kluxen FW, Schöffl F, Berchtold MW, Jockusch H.

Eur J Biochem. 1988 Sep 1;176(1):153-8.

21.

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