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Items: 17


Novel Transgenic Mouse Model for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure.

Sheng J, Wang Y, Turesky RJ, Kluetzman K, Zhang QY, Ding X.

Chem Res Toxicol. 2016 May 16;29(5):797-809. doi: 10.1021/acs.chemrestox.5b00529. Epub 2016 Apr 14.


Generation and characterization of a novel CYP2A13--transgenic mouse model.

Jia K, Li L, Liu Z, Hartog M, Kluetzman K, Zhang QY, Ding X.

Drug Metab Dispos. 2014 Aug;42(8):1341-8. doi: 10.1124/dmd.114.059188. Epub 2014 Jun 6.


Inhibition of follicle-stimulating hormone-induced preovulatory follicles in rats treated with a nonsteroidal negative allosteric modulator of follicle-stimulating hormone receptor.

Dias JA, Campo B, Weaver BA, Watts J, Kluetzman K, Thomas RM, Bonnet B, Mutel V, Poli SM.

Biol Reprod. 2014 Jan 30;90(1):19. doi: 10.1095/biolreprod.113.109397. Print 2014 Jan.


The maternal autoimmune environment affects the social behavior of offspring.

Zhang Y, Gao D, Kluetzman K, Mendoza A, Bolivar VJ, Reilly A, Jolly JK, Lawrence DA.

J Neuroimmunol. 2013 May 15;258(1-2):51-60. doi: 10.1016/j.jneuroim.2013.02.019. Epub 2013 Mar 26.


Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse model.

Wei Y, Li L, Zhou X, Zhang QY, Dunbar A, Liu F, Kluetzman K, Yang W, Ding X.

Drug Metab Dispos. 2013 Jan;41(1):132-40. doi: 10.1124/dmd.112.048736. Epub 2012 Oct 16.


Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model.

Wei Y, Wu H, Li L, Liu Z, Zhou X, Zhang QY, Weng Y, D'Agostino J, Ling G, Zhang X, Kluetzman K, Yao Y, Ding X.

Drug Metab Dispos. 2012 Jun;40(6):1144-50. doi: 10.1124/dmd.112.044826. Epub 2012 Mar 7.


Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa.

Li L, Wei Y, Van Winkle L, Zhang QY, Zhou X, Hu J, Xie F, Kluetzman K, Ding X.

J Pharmacol Exp Ther. 2011 Oct;339(1):62-71. doi: 10.1124/jpet.111.184671. Epub 2011 Jul 5.


A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.

Zhou X, Wei Y, Xie F, Laukaitis CM, Karn RC, Kluetzman K, Gu J, Zhang QY, Roberts DW, Ding X.

Mol Pharmacol. 2011 Apr;79(4):710-23. doi: 10.1124/mol.110.070045. Epub 2011 Jan 20.


A negative allosteric modulator demonstrates biased antagonism of the follicle stimulating hormone receptor.

Dias JA, Bonnet B, Weaver BA, Watts J, Kluetzman K, Thomas RM, Poli S, Mutel V, Campo B.

Mol Cell Endocrinol. 2011 Feb 20;333(2):143-50. doi: 10.1016/j.mce.2010.12.023. Epub 2010 Dec 22.


Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.

Zhou X, Zhuo X, Xie F, Kluetzman K, Shu YZ, Humphreys WG, Ding X.

J Pharmacol Exp Ther. 2010 Feb;332(2):578-87. doi: 10.1124/jpet.109.162610. Epub 2009 Nov 18.


Knock-in of the Oas1b(r) allele into a flavivirus-induced disease susceptible mouse generates the resistant phenotype.

Scherbik SV, Kluetzman K, Perelygin AA, Brinton MA.

Virology. 2007 Nov 25;368(2):232-7. Epub 2007 Sep 27.


DSCR1 (ADAPT78) lethality: evidence for a protective effect of trisomy 21 genes?

Kluetzman KS, Perez AV, Crawford DR.

Biochem Biophys Res Commun. 2005 Nov 18;337(2):595-601. Epub 2005 Sep 22.


Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: effects on development, reproduction, and microsomal cytochrome P450.

Wu L, Gu J, Cui H, Zhang QY, Behr M, Fang C, Weng Y, Kluetzman K, Swiatek PJ, Yang W, Kaminsky L, Ding X.

J Pharmacol Exp Ther. 2005 Jan;312(1):35-43. Epub 2004 Aug 24.


Conditional knockout of the mouse NADPH-cytochrome p450 reductase gene.

Wu L, Gu J, Weng Y, Kluetzman K, Swiatek P, Behr M, Zhang QY, Zhuo X, Xie Q, Ding X.

Genesis. 2003 Aug;36(4):177-81.


Posterior column ataxia and retinitis pigmentosa: a distinct clinical and genetic disorder.

Higgins JJ, Kluetzman K, Berciano J, Combarros O, Loveless JM.

Mov Disord. 2000 May;15(3):575-8.


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