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Items: 1 to 50 of 193

1.

Epigenetic regulation of RCAN1 expression in kidney disease and its role in podocyte injury.

Li H, Zhang W, Zhong F, Das GC, Xie Y, Li Z, Cai W, Jiang G, Choi J, Sidani M, Hyink DP, Lee K, Klotman PE, He JC.

Kidney Int. 2018 Dec;94(6):1160-1176. doi: 10.1016/j.kint.2018.07.023. Epub 2018 Oct 23.

PMID:
30366682
2.

Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.

Cheung JY, Gordon J, Wang J, Song J, Zhang XQ, Prado FJ, Shanmughapriya S, Rajan S, Tomar D, Tahrir FG, Gupta MK, Knezevic T, Merabova N, Kontos CD, McClung JM, Klotman PE, Madesh M, Khalili K, Feldman AM.

J Cell Physiol. 2019 Apr;234(4):4432-4444. doi: 10.1002/jcp.27232. Epub 2018 Sep 7.

PMID:
30256393
3.

Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3.

Cheung JY, Gordon J, Wang J, Song J, Zhang XQ, Tilley DG, Gao E, Koch WJ, Rabinowitz J, Klotman PE, Khalili K, Feldman AM.

Clin Transl Sci. 2015 Aug;8(4):305-10. doi: 10.1111/cts.12331. Epub 2015 Aug 24.

4.

Trends in the outcomes of end-stage renal disease secondary to human immunodeficiency virus-associated nephropathy.

Razzak Chaudhary S, Workeneh BT, Montez-Rath ME, Zolopa AR, Klotman PE, Winkelmayer WC.

Nephrol Dial Transplant. 2015 Oct;30(10):1734-40. doi: 10.1093/ndt/gfv207. Epub 2015 Jul 13.

5.

Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte.

Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE.

PLoS One. 2014 Jun 20;9(6):e100660. doi: 10.1371/journal.pone.0100660. eCollection 2014.

6.

Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury.

Potla U, Ni J, Vadaparampil J, Yang G, Leventhal JS, Campbell KN, Chuang PY, Morozov A, He JC, D'Agati VD, Klotman PE, Kaufman L.

J Clin Invest. 2014 Apr;124(4):1757-69. doi: 10.1172/JCI67846. Epub 2014 Mar 18.

7.

Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma.

Hutter R, Huang L, Speidl WS, Giannarelli C, Trubin P, Bauriedel G, Klotman ME, Fuster V, Badimon JJ, Klotman PE.

Circulation. 2013 Nov 26;128(22):2351-63. doi: 10.1161/CIRCULATIONAHA.113.004634. Epub 2013 Sep 16.

8.

Estimating kidney function in HIV-infected adults in Kenya: comparison to a direct measure of glomerular filtration rate by iohexol clearance.

Wyatt CM, Schwartz GJ, Owino Ong'or W, Abuya J, Abraham AG, Mboku C, M'mene LB, Koima WJ, Hotta M, Maier P, Klotman PE, Wools-Kaloustian K.

PLoS One. 2013 Aug 8;8(8):e69601. doi: 10.1371/journal.pone.0069601. eCollection 2013.

9.

Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase.

Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC.

J Am Soc Nephrol. 2013 Apr;24(5):801-11. doi: 10.1681/ASN.2012060590. Epub 2013 Apr 4.

10.

Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.

Sharma M, Magenheimer LK, Home T, Tamano KN, Singhal PC, Hyink DP, Klotman PE, Vanden Heuvel GB, Fields TA.

Am J Physiol Renal Physiol. 2013 Apr 15;304(8):F1127-36. doi: 10.1152/ajprenal.00475.2012. Epub 2013 Feb 6.

11.

Deletion of podocyte STAT3 mitigates the entire spectrum of HIV-1-associated nephropathy.

Gu L, Dai Y, Xu J, Mallipattu S, Kaufman L, Klotman PE, He JC, Chuang PY.

AIDS. 2013 Apr 24;27(7):1091-8. doi: 10.1097/QAD.0b013e32835f1ea1.

12.

Expression of HIV transgene aggravates kidney injury in diabetic mice.

Mallipattu SK, Liu R, Zhong Y, Chen EY, D'Agati V, Kaufman L, Ma'ayan A, Klotman PE, Chuang PY, He JC.

Kidney Int. 2013 Apr;83(4):626-34. doi: 10.1038/ki.2012.445. Epub 2013 Jan 16.

13.

Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans.

Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, Winkler CA, Kopp JB; SK Investigators.

Kidney Int. 2013 Jan;83(1):114-20. doi: 10.1038/ki.2012.263. Epub 2012 Jul 25.

14.

Glomerular MYH9 expression is reduced by HIV-1.

Hays T, D'Agati VD, Garellek JA, Warren T, Trubin ME, Hyink DP, He JC, Klotman PE.

AIDS. 2012 Apr 24;26(7):797-803. doi: 10.1097/QAD.0b013e328351f6cf.

15.

Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure.

Zhong Y, Wu Y, Liu R, Deng Y, Mallipattu SK, Klotman PE, Chuang PY, He JC.

Kidney Int. 2012 May;81(9):856-64. doi: 10.1038/ki.2011.467. Epub 2012 Jan 18.

16.

APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy.

Papeta N, Kiryluk K, Patel A, Sterken R, Kacak N, Snyder HJ, Imus PH, Mhatre AN, Lawani AK, Julian BA, Wyatt RJ, Novak J, Wyatt CM, Ross MJ, Winston JA, Klotman ME, Cohen DJ, Appel GB, D'Agati VD, Klotman PE, Gharavi AG.

J Am Soc Nephrol. 2011 Nov;22(11):1991-6. doi: 10.1681/ASN.2011040434. Epub 2011 Oct 13.

17.

Recent progress in HIV-associated nephropathy.

Wyatt CM, Meliambro K, Klotman PE.

Annu Rev Med. 2012;63:147-59. doi: 10.1146/annurev-med-041610-134224. Epub 2011 Sep 1. Review.

PMID:
21888512
18.

Pre-existing albuminuria predicts AIDS and non-AIDS mortality in women initiating antiretroviral therapy.

Wyatt CM, Hoover DR, Shi Q, Tien PC, Karim R, Cohen MH, Goderre JL, Seaberg EC, Lazar J, Young MA, Klotman PE, Anastos K.

Antivir Ther. 2011;16(4):591-6. doi: 10.3851/IMP1766.

19.

Career development of physician scientists: a survey of leaders in academic medicine.

Shea JA, Stern DT, Klotman PE, Clayton CP, O'Hara JL, Feldman MD, Griendling KK, Moss M, Straus SE, Jagsi R.

Am J Med. 2011 Aug;124(8):779-87. doi: 10.1016/j.amjmed.2011.04.004. No abstract available.

PMID:
21640329
20.

HIV-associated nephropathy: pathogenesis.

Medapalli RK, He JC, Klotman PE.

Curr Opin Nephrol Hypertens. 2011 May;20(3):306-11. doi: 10.1097/MNH.0b013e328345359a. Review.

21.

World Kidney Day 2011.

Hostetter TH, Kochis DJ, Shaffer RN, Chertow G, Harmon WE, Klotman PE, Powe NR, Sedor JR, Smedberg PC, Watnick S, Winkelmayer WC; ASN Public Policy Board.

J Am Soc Nephrol. 2011 Mar;22(3):397-8. doi: 10.1681/ASN.2011020115. Epub 2011 Feb 25. No abstract available.

22.

Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells.

Chen P, Chen BK, Mosoian A, Hays T, Ross MJ, Klotman PE, Klotman ME.

J Am Soc Nephrol. 2011 Mar;22(3):496-507. doi: 10.1681/ASN.2010040379. Epub 2011 Feb 18.

23.

Role of the retinoic acid receptor-α in HIV-associated nephropathy.

Ratnam KK, Feng X, Chuang PY, Verma V, Lu TC, Wang J, Jin Y, Farias EF, Napoli JL, Chen N, Kaufman L, Takano T, D'Agati VD, Klotman PE, He JC.

Kidney Int. 2011 Mar;79(6):624-634. doi: 10.1038/ki.2010.470. Epub 2010 Dec 8.

24.

HIV type-1 transgene expression in mice alters adipose tissue and adipokine levels: towards a rodent model of HIV type-1 lipodystrophy.

Villarroya J, Diaz-Delfin J, Hyink D, Domingo P, Giralt M, Klotman PE, Villarroya F.

Antivir Ther. 2010;15(7):1021-8. doi: 10.3851/IMP1669.

PMID:
21041917
25.

The future of malpractice reform.

Bishop TF, Klotman PE, Vladeck BC, Callahan MA.

Am J Med. 2010 Aug;123(8):673-4. doi: 10.1016/j.amjmed.2010.03.013. No abstract available.

PMID:
20670716
26.

Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis.

Kaufman L, Potla U, Coleman S, Dikiy S, Hata Y, Kurihara H, He JC, D'Agati VD, Klotman PE.

J Biol Chem. 2010 Aug 13;285(33):25677-85. doi: 10.1074/jbc.M110.133959. Epub 2010 Jun 18.

27.

HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells.

Snyder A, Alsauskas ZC, Leventhal JS, Rosenstiel PE, Gong P, Chan JJ, Barley K, He JC, Klotman ME, Ross MJ, Klotman PE.

AIDS. 2010 May 15;24(8):1107-19. doi: 10.1097/QAD.0b013e328337b0ab.

28.

Microalbuminuria is associated with all-cause and AIDS mortality in women with HIV infection.

Wyatt CM, Hoover DR, Shi Q, Seaberg E, Wei C, Tien PC, Karim R, Lazar J, Young MA, Cohen MH, Klotman PE, Anastos K.

J Acquir Immune Defic Syndr. 2010 Sep;55(1):73-7. doi: 10.1097/QAI.0b013e3181cc1070.

29.

The pathogenesis of HIV-associated nephropathy.

Kaufman L, Collins SE, Klotman PE.

Adv Chronic Kidney Dis. 2010 Jan;17(1):36-43. doi: 10.1053/j.ackd.2009.08.012. Review.

PMID:
20005487
30.

FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy.

Snyder A, Alsauskas Z, Gong P, Rosenstiel PE, Klotman ME, Klotman PE, Ross MJ.

J Virol. 2009 Nov;83(22):11983-8. doi: 10.1128/JVI.00034-09. Epub 2009 Sep 2.

31.

HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells.

Rosenstiel PE, Chan J, Snyder A, Planelles V, D'Agati VD, Klotman PE, Klotman ME.

AIDS. 2009 Sep 24;23(15):2054-6. doi: 10.1097/QAD.0b013e32833088a0.

32.

Reduction of Stat3 activity attenuates HIV-induced kidney injury.

Feng X, Lu TC, Chuang PY, Fang W, Ratnam K, Xiong H, Ouyang X, Shen Y, Levy DE, Hyink D, Klotman M, D'Agati V, Iyengar R, Klotman PE, He JC.

J Am Soc Nephrol. 2009 Oct;20(10):2138-46. doi: 10.1681/ASN.2008080879. Epub 2009 Jul 16.

33.

Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression.

Papeta N, Chan KT, Prakash S, Martino J, Kiryluk K, Ballard D, Bruggeman LA, Frankel R, Zheng Z, Klotman PE, Zhao H, D'Agati VD, Lifton RP, Gharavi AG.

J Clin Invest. 2009 May;119(5):1178-88. doi: 10.1172/JCI37131. Epub 2009 Apr 20.

34.

World Kidney Day 2009: problems and challenges in the emerging epidemic of kidney disease.

Szczech LA, Harmon W, Hostetter TH, Klotman PE, Powe NR, Sedor JR, Smedberg P, Himmelfarb J.

J Am Soc Nephrol. 2009 Mar;20(3):453-5. doi: 10.1681/ASN.2009010041. Epub 2009 Feb 25. No abstract available.

35.

Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus.

Chan KT, Papeta N, Martino J, Zheng Z, Frankel RZ, Klotman PE, D'Agati VD, Lifton RP, Gharavi AG.

Kidney Int. 2009 Feb;75(4):366-72. doi: 10.1038/ki.2008.625. Epub 2008 Dec 17.

36.

The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy.

Wyatt CM, Morgello S, Katz-Malamed R, Wei C, Klotman ME, Klotman PE, D'Agati VD.

Kidney Int. 2009 Feb;75(4):428-34. doi: 10.1038/ki.2008.604. Epub 2008 Dec 3.

37.

Localization of the nucleic acid channel regulatory subunit, cytosolic malate dehydrogenase.

Hanss B, Leal-Pinto E, Teixeira A, Tran B, Lee CH, Henderson SC, Klotman PE.

J Membr Biol. 2008 Nov-Dec;226(1-3):1-8. doi: 10.1007/s00232-008-9133-5. Epub 2008 Nov 18.

PMID:
19015805
38.

HIV-associated nephropathy: clinical presentation, pathology, and epidemiology in the era of antiretroviral therapy.

Wyatt CM, Klotman PE, D'Agati VD.

Semin Nephrol. 2008 Nov;28(6):513-22. doi: 10.1016/j.semnephrol.2008.08.005. Review.

39.

Kidney disease in HIV infection: introduction.

Wyatt CM, Klotman PE.

Semin Nephrol. 2008 Nov;28(6):511-2. doi: 10.1016/j.semnephrol.2008.08.004. No abstract available.

40.

The impact of hepatitis C virus coinfection on HIV-related kidney disease: a systematic review and meta-analysis.

Wyatt CM, Malvestutto C, Coca SG, Klotman PE, Parikh CR.

AIDS. 2008 Sep 12;22(14):1799-807. doi: 10.1097/QAD.0b013e32830e0152. Review.

41.

Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes.

Lu TC, Wang Z, Feng X, Chuang P, Fang W, Chen Y, Neves S, Maayan A, Xiong H, Liu Y, Iyengar R, Klotman PE, He JC.

Mol Cell Biol. 2008 Sep;28(18):5785-94. doi: 10.1128/MCB.00245-08. Epub 2008 Jul 14.

42.

HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells.

Rosenstiel PE, Gruosso T, Letourneau AM, Chan JJ, LeBlanc A, Husain M, Najfeld V, Planelles V, D'Agati VD, Klotman ME, Klotman PE.

Kidney Int. 2008 Oct;74(8):1049-58. doi: 10.1038/ki.2008.303. Epub 2008 Jul 9.

43.

HIV-1 upregulates VEGF in podocytes.

Korgaonkar SN, Feng X, Ross MD, Lu TC, D'Agati V, Iyengar R, Klotman PE, He JC.

J Am Soc Nephrol. 2008 May;19(5):877-83. doi: 10.1681/ASN.2007050629.

44.

HIV-associated nephropathy.

Wyatt CM, Rosenstiel PE, Klotman PE.

Contrib Nephrol. 2008;159:151-161. doi: 10.1159/000125831.

PMID:
18391591
45.

Fact and fiction: debunking myths in the US healthcare system.

Sarpel U, Vladeck BC, Divino CM, Klotman PE.

Ann Surg. 2008 Apr;247(4):563-9. doi: 10.1097/SLA.0b013e318159d566.

PMID:
18362617
46.

HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein.

Lu TC, He JC, Wang ZH, Feng X, Fukumi-Tominaga T, Chen N, Xu J, Iyengar R, Klotman PE.

J Biol Chem. 2008 Mar 28;283(13):8173-82. doi: 10.1074/jbc.M708920200. Epub 2008 Jan 30.

47.

HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers.

Serrano AL, Jardi M, Suelves M, Klotman PE, Munoz-Canoves P.

Front Biosci. 2008 Jan 1;13:2797-805.

PMID:
17981754
48.

Chronic kidney disease in HIV infection: an urban epidemic.

Wyatt CM, Winston JA, Malvestutto CD, Fishbein DA, Barash I, Cohen AJ, Klotman ME, Klotman PE.

AIDS. 2007 Oct 1;21(15):2101-3.

PMID:
17885301
49.

HIV-1 and HIV-Associated Nephropathy 25 Years Later.

Wyatt CM, Klotman PE.

Clin J Am Soc Nephrol. 2007 Jul;2 Suppl 1:S20-4. Review.

50.

Podocytes in HIV-associated nephropathy.

Lu TC, He JC, Klotman PE.

Nephron Clin Pract. 2007;106(2):c67-71. Epub 2007 Jun 6. Review.

PMID:
17570932

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