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Items: 12

1.

Driving cars to the clinic for solid tumors.

Castellarin M, Watanabe K, June CH, Kloss CC, Posey AD Jr.

Gene Ther. 2018 Jun 7. doi: 10.1038/s41434-018-0007-x. [Epub ahead of print]

PMID:
29880908
2.

Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication.

Kloss CC, Lee J, Zhang A, Chen F, Melenhorst JJ, Lacey SF, Maus MV, Fraietta JA, Zhao Y, June CH.

Mol Ther. 2018 Jul 5;26(7):1855-1866. doi: 10.1016/j.ymthe.2018.05.003. Epub 2018 May 8.

PMID:
29807781
3.

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.

Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM.

Sci Immunol. 2018 Jan 12;3(19). pii: eaal2736. doi: 10.1126/sciimmunol.aal2736.

4.

Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells.

Zhao Z, Condomines M, van der Stegen SJC, Perna F, Kloss CC, Gunset G, Plotkin J, Sadelain M.

Cancer Cell. 2015 Oct 12;28(4):415-428. doi: 10.1016/j.ccell.2015.09.004.

5.

Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma.

Johnson LA, Scholler J, Ohkuri T, Kosaka A, Patel PR, McGettigan SE, Nace AK, Dentchev T, Thekkat P, Loew A, Boesteanu AC, Cogdill AP, Chen T, Fraietta JA, Kloss CC, Posey AD Jr, Engels B, Singh R, Ezell T, Idamakanti N, Ramones MH, Li N, Zhou L, Plesa G, Seykora JT, Okada H, June CH, Brogdon JL, Maus MV.

Sci Transl Med. 2015 Feb 18;7(275):275ra22. doi: 10.1126/scitranslmed.aaa4963.

6.

Activation of the vascular niche supports leukemic progression and resistance to chemotherapy.

Poulos MG, Gars EJ, Gutkin MC, Kloss CC, Ginsberg M, Scandura JM, Rafii S, Butler JM.

Exp Hematol. 2014 Nov;42(11):976-986.e3. doi: 10.1016/j.exphem.2014.08.003. Epub 2014 Aug 29.

7.

Novel approaches to enhance the specificity and safety of engineered T cells.

Fedorov VD, Sadelain M, Kloss CC.

Cancer J. 2014 Mar-Apr;20(2):160-5. doi: 10.1097/PPO.0000000000000040.

PMID:
24667964
8.

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy.

Themeli M, Kloss CC, Ciriello G, Fedorov VD, Perna F, Gonen M, Sadelain M.

Nat Biotechnol. 2013 Oct;31(10):928-33. doi: 10.1038/nbt.2678. Epub 2013 Aug 11.

9.

CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia.

Davila ML, Kloss CC, Gunset G, Sadelain M.

PLoS One. 2013 Apr 9;8(4):e61338. doi: 10.1371/journal.pone.0061338. Print 2013.

10.

Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells.

Kloss CC, Condomines M, Cartellieri M, Bachmann M, Sadelain M.

Nat Biotechnol. 2013 Jan;31(1):71-5. doi: 10.1038/nbt.2459. Epub 2012 Dec 16.

11.

Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition.

Rafii S, Kloss CC, Butler JM, Ginsberg M, Gars E, Lis R, Zhan Q, Josipovic P, Ding BS, Xiang J, Elemento O, Zaninovic N, Rosenwaks Z, Sadelain M, Rafii JA, James D.

Blood. 2013 Jan 31;121(5):770-80. doi: 10.1182/blood-2012-07-444208. Epub 2012 Nov 20.

12.

A large-scale study of differential gene expression in monocyte-derived macrophages infected with several strains of Mycobacterium avium subspecies paratuberculosis.

Kabara E, Kloss CC, Wilson M, Tempelman RJ, Sreevatsan S, Janagama H, Coussens PM.

Brief Funct Genomics. 2010 May;9(3):220-37. doi: 10.1093/bfgp/elq009. Epub 2010 Apr 30.

PMID:
20495212

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