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Items: 1 to 50 of 157

1.

High Aldehyde Dehydrogenase Levels Are Detectable in the Serum of Patients with Lung Cancer and May Be Exploited as Screening Biomarkers.

Rossi A, Voigtlaender M, Klose H, Schlüter H, Schön G, Loges S, Paolini M, Bokemeyer C, Reck M, Tarro G, Binder M.

J Oncol. 2019 Aug 22;2019:8970645. doi: 10.1155/2019/8970645. eCollection 2019.

2.

OrganoCat Fractionation of Empty Fruit Bunches from Palm Trees into Lignin, Sugars, and Cellulose-Enriched Pulp.

Grande PM, Weidener D, Dietrich S, Dama M, Bellof M, Maas R, Pauly M, Leitner W, Klose H, Domínguez de María P.

ACS Omega. 2019 Aug 29;4(11):14451-14457. doi: 10.1021/acsomega.9b01371. eCollection 2019 Sep 10.

3.

The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension.

Hennigs JK, Lüneburg N, Stage A, Schmitz M, Körbelin J, Harbaum L, Matuszcak C, Mienert J, Bokemeyer C, Böger RH, Kiefmann R, Klose H.

Purinergic Signal. 2019 Sep;15(3):299-311. doi: 10.1007/s11302-019-09674-1. Epub 2019 Aug 8.

PMID:
31396838
4.

[Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension].

Rosenkranz S, Diller GP, Dumitrescu D, Ewert R, Ghofrani HA, Grünig E, Halank M, Held M, Kaemmerer H, Klose H, Kovacs G, Konstantinides S, Lang IM, Lange TJ, Leuchte H, Mayer E, Olschewski A, Olschewski H, Olsson KM, Opitz C, Schermuly RT, Seeger W, Wilkens H, Hoeper MM.

Dtsch Med Wochenschr. 2019 Sep;144(19):1367-1372. doi: 10.1055/a-0918-3772. Epub 2019 Jul 5. German.

5.

Right ventricular size and function under riociguat in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension (the RIVER study).

Marra AM, Halank M, Benjamin N, Bossone E, Cittadini A, Eichstaedt CA, Egenlauf B, Harutyunova S, Fischer C, Gall H, Ghofrani HA, Hoeper MM, Lange TJ, Olsson KM, Klose H, Grünig E.

Respir Res. 2018 Dec 19;19(1):258. doi: 10.1186/s12931-018-0957-y.

6.

Cologne consensus conference on pulmonary hypertension - Update 2018.

Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Hoeper MM.

Int J Cardiol. 2018 Dec 1;272S:1-3. doi: 10.1016/j.ijcard.2018.09.064. Epub 2018 Sep 22. No abstract available.

PMID:
30344062
7.

Risk assessment in medically treated chronic thromboembolic pulmonary hypertension patients.

Delcroix M, Staehler G, Gall H, Grünig E, Held M, Halank M, Klose H, Vonk-Noordegraaf A, Rosenkranz S, Pepke-Zaba J, Opitz CF, Gibbs JSR, Lange TJ, Tsangaris I, Huscher D, Pittrow D, Olsson KM, Hoeper MM.

Eur Respir J. 2018 Nov 8;52(5). pii: 1800248. doi: 10.1183/13993003.00248-2018. Print 2018 Nov.

PMID:
30337446
8.

Long-term safety and outcome of intravenous treprostinil via an implanted pump in pulmonary hypertension.

Richter MJ, Harutyunova S, Bollmann T, Classen S, Gall H, Gerhardt Md F, Grimminger F, Grimminger J, Grünig E, Guth S, Halank M, Heine A, Hoeper MM, Klose H, Lange TJ, Meyer K, Neurohr C, Nickolaus K, Olsson KM, Opitz CF, Rosenkranz S, Seyfarth HJ, Warnke C, Wiedenroth C, Ghofrani HA, Ewert R.

J Heart Lung Transplant. 2018 Oct;37(10):1235-1244. doi: 10.1016/j.healun.2018.06.006. Epub 2018 Jun 21.

PMID:
30293617
9.

TRM4 is essential for cellulose deposition in Arabidopsis seed mucilage by maintaining cortical microtubule organization and interacting with CESA3.

Yang B, Voiniciuc C, Fu L, Dieluweit S, Klose H, Usadel B.

New Phytol. 2019 Jan;221(2):881-895. doi: 10.1111/nph.15442. Epub 2018 Sep 13.

10.

Targeted therapy of pulmonary arterial hypertension: Updated recommendations from the Cologne Consensus Conference 2018.

Hoeper MM, Apitz C, Grünig E, Halank M, Ewert R, Kaemmerer H, Kabitz HJ, Kähler C, Klose H, Leuchte H, Ulrich S, Olsson KM, Distler O, Rosenkranz S, Ghofrani HA.

Int J Cardiol. 2018 Dec 1;272S:37-45. doi: 10.1016/j.ijcard.2018.08.082. Epub 2018 Aug 25.

PMID:
30190158
11.

General measures and supportive therapy for pulmonary arterial hypertension: Updated recommendations from the Cologne Consensus Conference 2018.

Grünig E, Benjamin N, Krüger U, Kaemmerer H, Harutyunova S, Olsson KM, Ulrich S, Gerhardt F, Neurohr C, Sablotzki A, Halank M, Marra AM, Kabitz HJ, Thimm G, Fliegel KG, Klose H.

Int J Cardiol. 2018 Dec 1;272S:30-36. doi: 10.1016/j.ijcard.2018.08.085. Epub 2018 Aug 27. Review.

PMID:
30190156
12.

Pulmonary hypertension due to lung diseases: Updated recommendations from the Cologne Consensus Conference 2018.

Olschewski H, Behr J, Bremer H, Claussen M, Douschan P, Halank M, Held M, Hoeper MM, Holt S, Klose H, Krüger S, Lange TJ, Reichenberger F, Skowasch D, Ulrich S, Wilkens H, Seeger W.

Int J Cardiol. 2018 Dec 1;272S:63-68. doi: 10.1016/j.ijcard.2018.08.043. Epub 2018 Aug 11. Review.

PMID:
30131231
13.

Right Ventricular Index for Risk Stratification of Patients with Pulmonary Arterial Hypertension.

Sinning C, Harbaum L, Schrage B, Rübsamen N, Magnussen C, Waschki B, Kleemann WH, Baaske KM, Kögler M, Ojeda F, Fischer C, Benjamin N, Westermann D, Zengin E, Schäfer U, Egenlauf B, Klose HF, Blankenberg S, Grünig E.

Respiration. 2018;96(3):249-258. doi: 10.1159/000489231. Epub 2018 Jul 12.

14.

Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.

Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi GA, Aytekin M, Dweik RA, Hennigs JK, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph TK, Hazen SL, Klose H, Schermuly RT, Rudolph V, Baldus S.

JCI Insight. 2018 Jun 7;3(11). pii: 97530. doi: 10.1172/jci.insight.97530. eCollection 2018 Jun 7.

15.

One-Step Lignocellulose Fractionation by using 2,5-Furandicarboxylic Acid as a Biogenic and Recyclable Catalyst.

Weidener D, Klose H, Leitner W, Schurr U, Usadel B, Domínguez de María P, Grande PM.

ChemSusChem. 2018 Jul 11;11(13):2051-2056. doi: 10.1002/cssc.201800653. Epub 2018 Jun 19.

PMID:
29791080
16.

Endoscopic lung volume reduction coil treatment in patients with very low FEV1: an observational study.

Simon M, Harbaum L, Oqueka T, Kluge S, Klose H.

Ther Adv Respir Dis. 2018 Jan-Dec;12:1753466618760133. doi: 10.1177/1753466618760133.

17.

The 6MWT as a prognostic tool in pulmonary arterial hypertension: results from the COMPERA registry.

Zelniker TA, Huscher D, Vonk-Noordegraaf A, Ewert R, Lange TJ, Klose H, Dumitrescu D, Halank M, Held M, Gall H, Pittrow D, Hoeper MM, Frankenstein L.

Clin Res Cardiol. 2018 Jun;107(6):460-470. doi: 10.1007/s00392-018-1207-5. Epub 2018 Jan 24.

PMID:
29368137
18.

OrganoCat pretreatment of perennial plants: Synergies between a biogenic fractionation and valuable feedstocks.

Damm T, Grande PM, Jablonowski ND, Thiele B, Disko U, Mann U, Schurr U, Leitner W, Usadel B, Domínguez de María P, Klose H.

Bioresour Technol. 2017 Nov;244(Pt 1):889-896. doi: 10.1016/j.biortech.2017.08.027. Epub 2017 Aug 9.

PMID:
28847077
19.

The Diagnosis and Treatment of Hemoptysis.

Ittrich H, Bockhorn M, Klose H, Simon M.

Dtsch Arztebl Int. 2017 Jun 5;114(21):371-381. doi: 10.3238/arztebl.2017.0371. Review.

20.

The safety and pharmacokinetics of rapid iloprost aerosol delivery via the BREELIB nebulizer in pulmonary arterial hypertension.

Gessler T, Ghofrani HA, Held M, Klose H, Leuchte H, Olschewski H, Rosenkranz S, Fels L, Li N, Ren D, Kaiser A, Schultze-Mosgau MH, Müllinger B, Rohde B, Seeger W.

Pulm Circ. 2017 Apr-Jun;7(2):505-513. doi: 10.1177/2045893217706691. Epub 2017 May 12.

21.

Plasma Drug Concentrations in Patients with Pulmonary Arterial Hypertension on Combination Treatment.

Grünig E, Ohnesorge J, Benjamin N, Burhenne J, Enderle Y, Egenlauf B, Fischer C, Harutyunova S, Huppertz A, Klose H, Haefeli WE.

Respiration. 2017;94(1):26-37. doi: 10.1159/000470916. Epub 2017 May 12.

22.

Insights into cell wall structure of Sida hermaphrodita and its influence on recalcitrance.

Damm T, Pattathil S, Günl M, Jablonowski ND, O'Neill M, Grün KS, Grande PM, Leitner W, Schurr U, Usadel B, Klose H.

Carbohydr Polym. 2017 Jul 15;168:94-102. doi: 10.1016/j.carbpol.2017.03.062. Epub 2017 Mar 20.

PMID:
28457468
23.

Exploratory analysis of the neutrophil to lymphocyte ratio in patients with pulmonary arterial hypertension.

Harbaum L, Baaske KM, Simon M, Oqueka T, Sinning C, Glatzel A, Lüneburg N, Sydow K, Bokemeyer C, Klose H.

BMC Pulm Med. 2017 Apr 26;17(1):72. doi: 10.1186/s12890-017-0407-5.

24.

Pulmonary Hypertension.

Hoeper MM, Ghofrani HA, Grünig E, Klose H, Olschewski H, Rosenkranz S.

Dtsch Arztebl Int. 2017 Feb 3;114(5):73-84. doi: 10.3238/arztebl.2017.0073. Review.

25.

[ESC guidelines 2015 pulmonary hypertension: diagnosis and treatment].

Opitz C, Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Hoeper M.

Dtsch Med Wochenschr. 2016 Nov;141(24):1764-1769. Epub 2016 Nov 30. German.

PMID:
27903027
26.

Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension.

Harbaum L, Renk E, Yousef S, Glatzel A, Lüneburg N, Hennigs JK, Oqueka T, Baumann HJ, Atanackovic D, Grünig E, Böger RH, Bokemeyer C, Klose H.

BMC Pulm Med. 2016 Nov 11;16(1):145.

27.

[Pulmonary Hypertension: Cologne Consensus Conference 2016].

Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Opitz C, Hoeper M.

Dtsch Med Wochenschr. 2016 Nov;141(24):1778-1782. Epub 2016 Nov 8. Review. German.

PMID:
27825176
28.

Endoscopic lung volume reduction coil treatment in patients with chronic hypercapnic respiratory failure: an observational study.

Simon M, Harbaum L, Oqueka T, Kluge S, Klose H.

Ther Adv Respir Dis. 2017 Jan;11(1):9-19. doi: 10.1177/1753465816676222. Epub 2016 Oct 27.

29.

Safety, Tolerability and Clinical Effects of a Rapid Dose Titration of Subcutaneous Treprostinil Therapy in Pulmonary Arterial Hypertension: A Prospective Multi-Centre Trial.

Grünig E, Benjamin N, Lange TJ, Krueger U, Klose H, Neurohr C, Wilkens H, Halank M, Seyfarth HJ, Held M, Traube A, Pernow M, Grover ER, Egenlauf B, Gerhardt F, Viethen T, Rosenkranz S.

Respiration. 2016;92(6):362-370. Epub 2016 Oct 27.

30.

[Pulmonary hypertension due to chronic lung disease: Recommendations of the Cologne Consensus Conference 2016].

Olschewski H, Behr J, Bremer H, Claussen M, Douschan P, Halank M, Held M, Hoeper MM, Holt S, Klose H, Krüger S, Lange TJ, Reichenberger F, Skowasch D, Ulrich S, Wilkens H, Seeger W.

Dtsch Med Wochenschr. 2016 Oct;141(S 01):S57-S61. Epub 2016 Oct 19. German.

PMID:
27760451
31.

[Targeted therapy of pulmonary arterial hypertension: Recommendations of the Cologne Consensus Conference 2016].

Hoeper MM, Apitz C, Grünig E, Halank M, Ewert R, Kaemmerer H, Kabitz HJ, Kähler C, Klose H, Leuchte H, Ulrich S, Olsson KM, Distler O, Rosenkranz S, Ghofrani HA.

Dtsch Med Wochenschr. 2016 Oct;141(S 01):S33-S41. Epub 2016 Oct 19. Review. German.

PMID:
27760448
32.

[General and supportive therapy of pulmonary arterial hypertension].

Grünig E, Benjamin N, Krüger U, Kaemmerer H, Harutyunova S, Olsson KM, Ulrich S, Gerhardt F, Neurohr C, Sablotzki A, Halank M, Kabitz HJ, Thimm G, Fliegel KG, Klose H.

Dtsch Med Wochenschr. 2016 Oct;141(S 01):S26-S32. Epub 2016 Oct 19. Review. German.

PMID:
27760447
33.

Bleeding Complications After Endoscopic Lung Volume Reduction Coil Treatment: A Retrospective Observational Study.

Simon M, Ittrich H, Harbaum L, Oqueka T, Kluge S, Klose H.

Arch Bronconeumol. 2016 Dec;52(12):590-595. doi: 10.1016/j.arbres.2016.04.012. Epub 2016 Aug 12. English, Spanish.

34.

Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?

Lüneburg N, Siques P, Brito J, Arriaza K, Pena E, Klose H, Leon-Velarde F, Böger RH.

Pulm Med. 2016;2016:6578578. doi: 10.1155/2016/6578578. Epub 2016 May 30.

35.

COPD-associated pulmonary hypertension: clinical implications and current methods for treatment.

Grimminger J, Ghofrani HA, Weissmann N, Klose H, Grimminger F.

Expert Rev Respir Med. 2016 Jul;10(7):755-66. doi: 10.1080/17476348.2016.1190275. Epub 2016 Jun 7. Review.

PMID:
27212458
36.

Value of Computed Tomography of the Chest in Subjects With ARDS: A Retrospective Observational Study.

Simon M, Braune S, Laqmani A, Metschke M, Berliner C, Kalsow M, Klose H, Kluge S.

Respir Care. 2016 Mar;61(3):316-23. doi: 10.4187/respcare.04308. Epub 2015 Dec 8.

37.

Pulmonary Hypertension in Patients with Chronic Fibrosing Idiopathic Interstitial Pneumonias.

Hoeper MM, Behr J, Held M, Grunig E, Vizza CD, Vonk-Noordegraaf A, Lange TJ, Claussen M, Grohé C, Klose H, Olsson KM, Zelniker T, Neurohr C, Distler O, Wirtz H, Opitz C, Huscher D, Pittrow D, Gibbs JS.

PLoS One. 2015 Dec 2;10(12):e0141911. doi: 10.1371/journal.pone.0141911. eCollection 2015.

38.

Right heart failure in pregnant women with cyanotic congenital heart disease--The good, the bad and the ugly.

Zengin E, Sinning C, Schrage B, Mueller GC, Klose H, Sachweh J, Goepfert M, Hueneke B, Blankenberg S, Kozlik-Feldmann R.

Int J Cardiol. 2016 Jan 1;202:773-5. doi: 10.1016/j.ijcard.2015.10.036. Epub 2015 Oct 9. No abstract available.

PMID:
26474467
39.

Does circulating IL-17 identify a subset of patients with idiopathic pulmonary arterial hypertension?

Harbaum L, Oqueka T, Glatzel A, Hennigs JK, Lüneburg N, Klose H.

Chest. 2015 Oct;148(4):e131-e132. doi: 10.1378/chest.15-0963. No abstract available.

PMID:
26437826
40.

MR-proADM Predicts Exercise Capacity and Survival Superior to Other Biomarkers in PH.

Kolditz M, Seyfarth HJ, Wilkens H, Ewert R, Bollmann T, Dinter C, Hertel S, Klose H, Opitz C, Grünig E, Höffken G, Halank M.

Lung. 2015 Dec;193(6):901-10. doi: 10.1007/s00408-015-9802-y. Epub 2015 Sep 12.

PMID:
26363916
41.

Exercise training improves peak oxygen consumption and haemodynamics in patients with severe pulmonary arterial hypertension and inoperable chronic thrombo-embolic pulmonary hypertension: a prospective, randomized, controlled trial.

Ehlken N, Lichtblau M, Klose H, Weidenhammer J, Fischer C, Nechwatal R, Uiker S, Halank M, Olsson K, Seeger W, Gall H, Rosenkranz S, Wilkens H, Mertens D, Seyfarth HJ, Opitz C, Ulrich S, Egenlauf B, Grünig E.

Eur Heart J. 2016 Jan 1;37(1):35-44. doi: 10.1093/eurheartj/ehv337. Epub 2015 Jul 31.

42.

[Therapy of Pulmonary Arterial Hypertension].

Klose H, Harbaum L, Oqueka T, Simon M, Grünig E.

Pneumologie. 2015 Aug;69(8):483-93; quiz 494-5. doi: 10.1055/s-0034-1392103. Epub 2015 Jul 28. German.

43.

Long-term safety and efficacy of imatinib in pulmonary arterial hypertension.

Frost AE, Barst RJ, Hoeper MM, Chang HJ, Frantz RP, Fukumoto Y, Galié N, Hassoun PM, Klose H, Matsubara H, Morrell NW, Peacock AJ, Pfeifer M, Simonneau G, Tapson VF, Torres F, Dario Vizza C, Lawrence D, Yang W, Felser JM, Quinn DA, Ghofrani HA.

J Heart Lung Transplant. 2015 Nov;34(11):1366-75. doi: 10.1016/j.healun.2015.05.025. Epub 2015 Jun 11.

44.

[Pulmonary hypertension: Possible genetic causes and therapeutic options].

Grünig E, Eichstaedt CA, Ehlken N, Mayer E, Klose H.

Herz. 2015 May;40(3):457-68; quiz 469-70. doi: 10.1007/s00059-015-4230-6. German.

PMID:
25963173
45.

[Dyspnoea in Patients with Pulmonary Hypertension (PH) - a Survey in Spezialized German PH Centres].

Ewert R, Wilkens H, Skowasch D, Reppel M, Bollmann T, Halank M, Held M, Klose H, Gall H, Lange TJ, Opitz CF, Seyfarth HJ, Winkler J.

Pneumologie. 2015 Jun;69(6):361-5. doi: 10.1055/s-0034-1391893. Epub 2015 Apr 21. German.

46.

Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension.

Wellbrock J, Harbaum L, Stamm H, Hennigs JK, Schulz B, Klose H, Bokemeyer C, Fiedler W, Lüneburg N.

Lung. 2015 Aug;193(4):567-70. doi: 10.1007/s00408-015-9735-5. Epub 2015 Apr 30.

PMID:
25926293
47.

Cell wall modification in tobacco by differential targeting of recombinant endoglucanase from Trichoderma reesei.

Klose H, Günl M, Usadel B, Fischer R, Commandeur U.

BMC Plant Biol. 2015 Feb 13;15:54. doi: 10.1186/s12870-015-0443-3.

48.

[Riociguat: stimulator of soluble guanylate-cyclase. New mode of action for the treatment of pulmonary arterial and non operable chronic thromboembolic pulmonary hypertension].

Leuchte HH, Behr J, Ewert R, Ghofrani HA, Grünig E, Halank M, Held M, Klose H, Rosenkranz S, Schermuly RT, Wilkens H, Hoeper MM.

Pneumologie. 2015 Mar;69(3):135-43. doi: 10.1055/s-0034-1391435. Epub 2015 Mar 6. Review. German.

49.
50.

[Imatinib for pulmonary arterial hypertension].

Hoeper MM, Opitz C, Olschewski H, Ulrich S, Speich R, Behr J, Halank M, Wilkens H, Klose H, Lange TJ, Grünig E, Seeger W, Ewert R, Borst MM, Welte T, Rosenkranz S, Ghofrani HA.

Dtsch Med Wochenschr. 2014 Dec;139 Suppl 4:S151-4. doi: 10.1055/s-0034-1387457. Epub 2014 Dec 9. Review. German. No abstract available.

PMID:
25489685

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