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Items: 1 to 50 of 118

1.

Shotgun lipidomics discovered diurnal regulation of lipid metabolism linked to insulin sensitivity in non-diabetic men.

Kessler K, Gerl MJ, Hornemann S, Damm M, Klose C, Petzke KJ, Kemper M, Weber D, Rudovich N, Grune T, Simons K, Kramer A, Pfeiffer AFH, Pivovarova-Ramich O.

J Clin Endocrinol Metab. 2019 Nov 4. pii: dgz176. doi: 10.1210/clinem/dgz176. [Epub ahead of print]

PMID:
31680138
2.

Integrative analysis of prognostic biomarkers derived from multiomics panels helps discrimination of chronic kidney disease trajectories in people with type 2 diabetes.

Kammer M, Heinzel A, Willency JA, Duffin KL, Mayer G, Simons K, Gerl MJ, Klose C, Heinze G, Reindl-Schwaighofer R, Hu K, Perco P, Eder S, Rosivall L, Mark PB, Ju W, Kretzler M, McCarthy MI, Heerspink HL, Wiecek A, Gomez MF, Oberbauer R; BEAt-DKD Consortium.

Kidney Int. 2019 Aug 30. pii: S0085-2538(19)30841-5. doi: 10.1016/j.kint.2019.07.025. [Epub ahead of print]

PMID:
31679767
3.

[Design and Evaluation of a Clinical Investigator Training for Student-lead Prospective Multicentre Clinical Trials: a CHIR-Net SIGMA Research-based Learning Project].

Rädeker L, Schwab M, Frey PE, Friedrich M, Sliwinski S, Steinle J, Fink CA, Leuk A, Ganschow P, Ottawa GB, Klose C, Feißt M, Dörr-Harim C, Tenckhoff S, Mihaljevic AL.

Zentralbl Chir. 2019 Oct 28. doi: 10.1055/a-1007-1995. [Epub ahead of print] German.

PMID:
31658485
4.

Machine learning of human plasma lipidomes for obesity estimation in a large population cohort.

Gerl MJ, Klose C, Surma MA, Fernandez C, Melander O, Männistö S, Borodulin K, Havulinna AS, Salomaa V, Ikonen E, Cannistraci CV, Simons K.

PLoS Biol. 2019 Oct 18;17(10):e3000443. doi: 10.1371/journal.pbio.3000443. eCollection 2019 Oct.

5.

Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial.

Mendes Jorge M, Ouermi L, Meissner P, Compaoré G, Coulibaly B, Nebie E, Krisam J, Klose C, Kieser M, Jahn A, Lu G, D Alessandro U, Sié A, Mockenhaupt FP, Müller O.

PLoS One. 2019 Oct 10;14(10):e0222993. doi: 10.1371/journal.pone.0222993. eCollection 2019.

6.

Differential phosphorylation of the N-terminal extension regulates phytochrome B signaling.

Viczián A, Ádám É, Staudt AM, Lambert D, Klement E, Romero Montepaone S, Hiltbrunner A, Casal J, Schäfer E, Nagy F, Klose C.

New Phytol. 2019 Oct 9. doi: 10.1111/nph.16243. [Epub ahead of print]

PMID:
31596952
7.

Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis.

Schönenberger S, Hendén PL, Simonsen CZ, Uhlmann L, Klose C, Pfaff JAR, Yoo AJ, Sørensen LH, Ringleb PA, Wick W, Kieser M, Möhlenbruch MA, Rasmussen M, Rentzos A, Bösel J.

JAMA. 2019 Oct 1;322(13):1283-1293. doi: 10.1001/jama.2019.11455.

PMID:
31573636
8.

Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Tabassum R, Rämö JT, Ripatti P, Koskela JT, Kurki M, Karjalainen J, Palta P, Hassan S, Nunez-Fontarnau J, Kiiskinen TTJ, Söderlund S, Matikainen N, Gerl MJ, Surma MA, Klose C, Stitziel NO, Laivuori H, Havulinna AS, Service SK, Salomaa V, Pirinen M; FinnGen Project, Jauhiainen M, Daly MJ, Freimer NB, Palotie A, Taskinen MR, Simons K, Ripatti S.

Nat Commun. 2019 Sep 24;10(1):4329. doi: 10.1038/s41467-019-11954-8.

9.

A simulation model for the degradation of magnesium-based bone implants.

Gartzke AK, Julmi S, Klose C, Waselau AC, Meyer-Lindenberg A, Maier HJ, Besdo S, Wriggers P.

J Mech Behav Biomed Mater. 2019 Sep 5;101:103411. doi: 10.1016/j.jmbbm.2019.103411. [Epub ahead of print]

PMID:
31546176
10.

The molecular basis of chaperone-mediated interleukin 23 assembly control.

Meier S, Bohnacker S, Klose CJ, Lopez A, Choe CA, Schmid PWN, Bloemeke N, Rührnößl F, Haslbeck M, Bieren JE, Sattler M, Huang PS, Feige MJ.

Nat Commun. 2019 Sep 11;10(1):4121. doi: 10.1038/s41467-019-12006-x.

11.

Osh Proteins Control Nanoscale Lipid Organization Necessary for PI(4,5)P2 Synthesis.

Nishimura T, Gecht M, Covino R, Hummer G, Surma MA, Klose C, Arai H, Kono N, Stefan CJ.

Mol Cell. 2019 Sep 5;75(5):1043-1057.e8. doi: 10.1016/j.molcel.2019.06.037. Epub 2019 Aug 8.

12.

In Vivo Spectroscopy.

Klose C.

Methods Mol Biol. 2019;2026:113-120. doi: 10.1007/978-1-4939-9612-4_8.

PMID:
31317406
13.

Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population-Ascertained Hyperlipidemias.

Rämö JT, Ripatti P, Tabassum R, Söderlund S, Matikainen N, Gerl MJ, Klose C, Surma MA, Stitziel NO, Havulinna AS, Pirinen M, Salomaa V, Freimer NB, Jauhiainen M, Palotie A, Taskinen MR, Simons K, Ripatti S.

J Am Heart Assoc. 2019 Jul 2;8(13):e012415. doi: 10.1161/JAHA.119.012415. Epub 2019 Jun 29.

14.

eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.

Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A.

Science. 2019 May 3;364(6439):491-495. doi: 10.1126/science.aaw2922.

15.

Children of Mentally III Parents at Risk Evaluation (COMPARE): Design and Methods of a Randomized Controlled Multicenter Study-Part I.

Christiansen H, Reck C, Zietlow AL, Otto K, Steinmayr R, Wirthwein L, Weigelt S, Stark R, Ebert DD, Buntrock C, Krisam J, Klose C, Kieser M, Schwenck C.

Front Psychiatry. 2019 Mar 26;10:128. doi: 10.3389/fpsyt.2019.00128. eCollection 2019.

17.

Processing and coating of open-pored absorbable magnesium-based bone implants.

Julmi S, Krüger AK, Waselau AC, Meyer-Lindenberg A, Wriggers P, Klose C, Maier HJ.

Mater Sci Eng C Mater Biol Appl. 2019 May;98:1073-1086. doi: 10.1016/j.msec.2018.12.125. Epub 2019 Jan 21.

PMID:
30812991
18.

Comprehensive and quantitative analysis of white and brown adipose tissue by shotgun lipidomics.

Grzybek M, Palladini A, Alexaki VI, Surma MA, Simons K, Chavakis T, Klose C, Coskun Ü.

Mol Metab. 2019 Apr;22:12-20. doi: 10.1016/j.molmet.2019.01.009. Epub 2019 Jan 30.

19.

Interleukin-22 protects intestinal stem cells against genotoxic stress.

Gronke K, Hernández PP, Zimmermann J, Klose CSN, Kofoed-Branzk M, Guendel F, Witkowski M, Tizian C, Amann L, Schumacher F, Glatt H, Triantafyllopoulou A, Diefenbach A.

Nature. 2019 Feb;566(7743):249-253. doi: 10.1038/s41586-019-0899-7. Epub 2019 Jan 30.

20.

Neuronal regulation of innate lymphoid cells.

Klose CS, Artis D.

Curr Opin Immunol. 2019 Feb;56:94-99. doi: 10.1016/j.coi.2018.11.002. Epub 2018 Dec 7. Review.

PMID:
30530300
21.

Prospective multicentre cohort study of patient-reported outcomes and complications following major abdominal neoplastic surgery (PATRONUS) - study protocol for a CHIR-Net student-initiated German medical audit study (CHIR-Net SIGMA study).

Fink CA, Friedrich M, Frey PE, Rädeker L, Leuck A, Bruckner T, Feisst M, Tenckhoff S, Klose C, Dörr-Harim C, Neudecker J, Mihaljevic AL.

BMC Surg. 2018 Oct 29;18(1):90. doi: 10.1186/s12893-018-0422-3.

22.

Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients.

Gerl MJ, Vaz WLC, Domingues N, Klose C, Surma MA, Sampaio JL, Almeida MS, Rodrigues G, Araújo-Gonçalves P, Ferreira J, Borbinha C, Marto JP, Viana-Baptista M, Simons K, Vieira OV.

Sci Rep. 2018 Oct 3;8(1):14764. doi: 10.1038/s41598-018-33116-4.

23.

Fast current-driven domain walls and small skyrmions in a compensated ferrimagnet.

Caretta L, Mann M, Büttner F, Ueda K, Pfau B, Günther CM, Hessing P, Churikova A, Klose C, Schneider M, Engel D, Marcus C, Bono D, Bagschik K, Eisebitt S, Beach GSD.

Nat Nanotechnol. 2018 Dec;13(12):1154-1160. doi: 10.1038/s41565-018-0255-3. Epub 2018 Sep 17.

PMID:
30224795
24.

Precision and reproducibility of automated computer-guided Psoriasis Area and Severity Index measurements in comparison with trained physicians.

Fink C, Alt C, Uhlmann L, Klose C, Enk A, Haenssle HA.

Br J Dermatol. 2019 Feb;180(2):390-396. doi: 10.1111/bjd.17200. Epub 2018 Oct 14.

PMID:
30218575
25.

Whole brain radiation therapy alone versus radiosurgery for patients with 1-10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial.

Bernhardt D, Hommertgen A, Schmitt D, El Shafie R, Paul A, König L, Mair-Walther J, Krisam J, Klose C, Welzel T, Hörner-Rieber J, Kappes J, Thomas M, Heußel CP, Steins M, Kieser M, Debus J, Rieken S.

Trials. 2018 Jul 16;19(1):388. doi: 10.1186/s13063-018-2745-x.

26.

Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183.

Chu C, Moriyama S, Li Z, Zhou L, Flamar AL, Klose CSN, Moeller JB, Putzel GG, Withers DR, Sonnenberg GF, Artis D.

Cell Rep. 2018 Jun 26;23(13):3750-3758. doi: 10.1016/j.celrep.2018.05.099.

28.

Association of Blood Pressure With Short- and Long-Term Functional Outcome After Stroke Thrombectomy: Post Hoc Analysis of the SIESTA Trial.

Schönenberger S, Uhlmann L, Ungerer M, Pfaff J, Nagel S, Klose C, Bendszus M, Wick W, Ringleb PA, Kieser M, Möhlenbruch MA, Bösel J.

Stroke. 2018 Jun;49(6):1451-1456. doi: 10.1161/STROKEAHA.117.019709. Epub 2018 May 2.

PMID:
29720440
29.

Intra- and interobserver variability of image-based PASI assessments in 120 patients suffering from plaque-type psoriasis.

Fink C, Alt C, Uhlmann L, Klose C, Enk A, Haenssle HA.

J Eur Acad Dermatol Venereol. 2018 Aug;32(8):1314-1319. doi: 10.1111/jdv.14960. Epub 2018 Apr 27.

PMID:
29569769
30.

Robotic Radiosurgery for Brain Metastases Diagnosed With Either SPACE or MPRAGE Sequence (CYBER-SPACE)-A Single-Center Prospective Randomized Trial.

El Shafie RA, Paul A, Bernhardt D, Lang K, Welzel T, Sprave T, Hommertgen A, Krisam J, Schmitt D, Klüter S, Schubert K, Klose C, Kieser M, Debus J, Rieken S.

Neurosurgery. 2019 Jan 1;84(1):253-260. doi: 10.1093/neuros/nyy026.

PMID:
29554321
31.

Evaluation of Stereotactic Radiotherapy of the Resection Cavity After Surgery of Brain Metastases Compared to Postoperative Whole-Brain Radiotherapy (ESTRON)-A Single-Center Prospective Randomized Trial.

El Shafie RA, Paul A, Bernhardt D, Hauswald H, Welzel T, Sprave T, Hommertgen A, Krisam J, Schmitt D, Klüter S, Schubert K, Klose C, Kieser M, Debus J, Rieken S.

Neurosurgery. 2018 Sep 1;83(3):566-573. doi: 10.1093/neuros/nyy021.

PMID:
29528419
32.

Lack of Type 2 Innate Lymphoid Cells Promotes a Type I-Driven Enhanced Immune Response in Contact Hypersensitivity.

Rafei-Shamsabadi DA, van de Poel S, Dorn B, Kunz S, Martin SF, Klose CSN, Arnold SJ, Tanriver Y, Ebert K, Diefenbach A, Halim TYF, McKenzie ANJ, Jakob T.

J Invest Dermatol. 2018 Sep;138(9):1962-1972. doi: 10.1016/j.jid.2018.03.001. Epub 2018 Mar 9.

33.

β2-adrenergic receptor-mediated negative regulation of group 2 innate lymphoid cell responses.

Moriyama S, Brestoff JR, Flamar AL, Moeller JB, Klose CSN, Rankin LC, Yudanin NA, Monticelli LA, Putzel GG, Rodewald HR, Artis D.

Science. 2018 Mar 2;359(6379):1056-1061. doi: 10.1126/science.aan4829.

PMID:
29496881
34.

PWWP-DOMAIN INTERACTOR OF POLYCOMBS1 Interacts with Polycomb-Group Proteins and Histones and Regulates Arabidopsis Flowering and Development.

Hohenstatt ML, Mikulski P, Komarynets O, Klose C, Kycia I, Jeltsch A, Farrona S, Schubert D.

Plant Cell. 2018 Jan;30(1):117-133. doi: 10.1105/tpc.17.00117. Epub 2018 Jan 12.

35.

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.

Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U.

PLoS Genet. 2018 Jan 10;14(1):e1007171. doi: 10.1371/journal.pgen.1007171. eCollection 2018 Jan.

36.

Cell Size and Growth Rate Are Modulated by TORC2-Dependent Signals.

Lucena R, Alcaide-Gavilán M, Schubert K, He M, Domnauer MG, Marquer C, Klose C, Surma MA, Kellogg DR.

Curr Biol. 2018 Jan 22;28(2):196-210.e4. doi: 10.1016/j.cub.2017.11.069. Epub 2017 Dec 28.

37.

Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells.

Hwang S, Gustafsson HT, O'Sullivan C, Bisceglia G, Huang X, Klose C, Schevchenko A, Dickson RC, Cavaliere P, Dephoure N, Torres EM.

Cell Rep. 2017 Dec 26;21(13):3807-3818. doi: 10.1016/j.celrep.2017.11.103.

38.

PCH1 and PCHL promote photomorphogenesis in plants by controlling phytochrome B dark reversion.

Enderle B, Sheerin DJ, Paik I, Kathare PK, Schwenk P, Klose C, Ulbrich MH, Huq E, Hiltbrunner A.

Nat Commun. 2017 Dec 20;8(1):2221. doi: 10.1038/s41467-017-02311-8.

39.

Erratum: The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.

Nature. 2017 Nov 30;551(7682):658. doi: 10.1038/nature24480. Epub 2017 Nov 15.

PMID:
29143821
40.

ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis.

Levental KR, Surma MA, Skinkle AD, Lorent JH, Zhou Y, Klose C, Chang JT, Hancock JF, Levental I.

Sci Adv. 2017 Nov 8;3(11):eaao1193. doi: 10.1126/sciadv.aao1193. eCollection 2017 Nov.

41.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S.

J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.

42.

Assessment of renal function in routine care of people living with HIV on ART in a resource-limited setting in urban Zambia.

Deckert A, Neuhann F, Klose C, Bruckner T, Beiersmann C, Haloka J, Nsofwa M, Banda G, Brune M, Reutter H, Rothenbacher D, Zeier M.

PLoS One. 2017 Sep 20;12(9):e0184766. doi: 10.1371/journal.pone.0184766. eCollection 2017.

43.

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.

Nature. 2017 Sep 21;549(7672):351-356. doi: 10.1038/nature24029. Epub 2017 Sep 13. Erratum in: Nature. 2017 Nov 15;:.

44.

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.

Klose CSN, Mahlakõiv T, Moeller JB, Rankin LC, Flamar AL, Kabata H, Monticelli LA, Moriyama S, Putzel GG, Rakhilin N, Shen X, Kostenis E, König GM, Senda T, Carpenter D, Farber DL, Artis D.

Nature. 2017 Sep 14;549(7671):282-286. doi: 10.1038/nature23676. Epub 2017 Sep 6.

45.

A committed postselection precursor to natural TCRαβ+ intraepithelial lymphocytes.

Klose CSN, Hummel JF, Faller L, d'Hargues Y, Ebert K, Tanriver Y.

Mucosal Immunol. 2018 Mar;11(2):333-344. doi: 10.1038/mi.2017.54. Epub 2017 Jul 26.

PMID:
28745324
46.

Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs.

Nussbaum K, Burkhard SH, Ohs I, Mair F, Klose CSN, Arnold SJ, Diefenbach A, Tugues S, Becher B.

J Exp Med. 2017 Aug 7;214(8):2331-2347. doi: 10.1084/jem.20162031. Epub 2017 Jul 11.

47.

Heritability and responses to high fat diet of plasma lipidomics in a twin study.

Frahnow T, Osterhoff MA, Hornemann S, Kruse M, Surma MA, Klose C, Simons K, Pfeiffer AFH.

Sci Rep. 2017 Jun 16;7(1):3750. doi: 10.1038/s41598-017-03965-6.

48.

The Impact of Conscious Sedation versus General Anesthesia for Stroke Thrombectomy on the Predictive Value of Collateral Status: A Post Hoc Analysis of the SIESTA Trial.

Schönenberger S, Pfaff J, Uhlmann L, Klose C, Nagel S, Ringleb PA, Hacke W, Kieser M, Bendszus M, Möhlenbruch MA, Bösel J.

AJNR Am J Neuroradiol. 2017 Aug;38(8):1580-1585. doi: 10.3174/ajnr.A5243. Epub 2017 Jun 8.

49.

Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry.

Sadowski T, Klose C, Gerl MJ, Wójcik-Maciejewicz A, Herzog R, Simons K, Reich A, Surma MA.

Sci Rep. 2017 Mar 7;7:43761. doi: 10.1038/srep43761.

50.

New insights of red light-induced development.

Viczián A, Klose C, Ádám É, Nagy F.

Plant Cell Environ. 2017 Nov;40(11):2457-2468. doi: 10.1111/pce.12880. Epub 2017 Feb 18. Review.

PMID:
27943362

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