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Items: 1 to 50 of 160

1.

Comparison of the liquid and lyophilized formulations of Prolastin®-C for Alpha1-Antitrypsin deficiency: Biochemical characteristics, pharmacokinetics, safety and neoantigenicity in rabbits.

Arora V, Cruz M, Lang J, Klos AM, Merritt WK, Price J, Taylor G, Vandeberg P, Wee K, Willis T.

Biologicals. 2019 Nov;62:77-84. doi: 10.1016/j.biologicals.2019.09.002. Epub 2019 Sep 12.

PMID:
31522909
2.

An assessment of energy expenditure of soldiers serving in the Polish chemical units, performing training tasks in 2 types of personal chemical protective clothing - comparative studies.

Bertrandt J, Kłos A, Łakomy R, Bertrandt B.

Int J Occup Med Environ Health. 2019 Oct 16;32(5):645-652. doi: 10.13075/ijomeh.1896.01382. Epub 2019 Sep 10.

3.

Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections.

Muenstermann M, Strobel L, Klos A, Wetsel RA, Woodruff TM, Köhl J, Johswich KO.

Virulence. 2019 Dec;10(1):677-694. doi: 10.1080/21505594.2019.1640035.

5.

Enhanced activation of interleukin-10, heme oxygenase-1, and AKT in C5aR2-deficient mice is associated with protection from ischemia reperfusion injury-induced inflammation and fibrosis.

Thorenz A, Derlin K, Schröder C, Dressler L, Vijayan V, Pradhan P, Immenschuh S, Jörns A, Echtermeyer F, Herzog C, Chen R, Rong S, Bräsen JH, van Kooten C, Kirsch T, Klemann C, Meier M, Klos A, Haller H, Hensen B, Gueler F.

Kidney Int. 2018 Oct;94(4):741-755. doi: 10.1016/j.kint.2018.04.005. Epub 2018 Jun 21.

PMID:
29935951
6.

Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection.

Rother M, Gonzalez E, Teixeira da Costa AR, Wask L, Gravenstein I, Pardo M, Pietzke M, Gurumurthy RK, Angermann J, Laudeley R, Glage S, Meyer M, Chumduri C, Kempa S, Dinkel K, Unger A, Klebl B, Klos A, Meyer TF.

Cell Host Microbe. 2018 May 9;23(5):661-671.e8. doi: 10.1016/j.chom.2018.04.002. Epub 2018 Apr 26.

7.

Using moss and lichens in biomonitoring of heavy-metal contamination of forest areas in southern and north-eastern Poland.

Kłos A, Ziembik Z, Rajfur M, Dołhańczuk-Śródka A, Bochenek Z, Bjerke JW, Tømmervik H, Zagajewski B, Ziółkowski D, Jerz D, Zielińska M, Krems P, Godyń P, Marciniak M, Świsłowski P.

Sci Total Environ. 2018 Jun 15;627:438-449. doi: 10.1016/j.scitotenv.2018.01.211. Epub 2018 Feb 3.

PMID:
29426166
8.

Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment.

Herrmann JB, Muenstermann M, Strobel L, Schubert-Unkmeir A, Woodruff TM, Gray-Owen SD, Klos A, Johswich KO.

mBio. 2018 Jan 23;9(1). pii: e01755-17. doi: 10.1128/mBio.01755-17.

9.

Effect of 3-year education in the Main Fire Service School on the fitness level of students.

Tomczak A, Bertrandt J, Kłos A, Szymańska W, Stankiewicz W.

Ann Agric Environ Med. 2017 Dec 23;24(4):628-631. doi: 10.5604/12321966.1232765. Epub 2017 May 11.

10.

The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments.

Luo S, Dasari P, Reiher N, Hartmann A, Jacksch S, Wende E, Barz D, Niemiec MJ, Jacobsen I, Beyersdorf N, Hünig T, Klos A, Skerka C, Zipfel PF.

Mol Immunol. 2018 Jan;93:266-277. doi: 10.1016/j.molimm.2017.07.010. Epub 2017 Aug 30.

PMID:
28860090
11.

Formyl-peptide receptor 2 governs leukocyte influx in local Staphylococcus aureus infections.

Weiss E, Hanzelmann D, Fehlhaber B, Klos A, von Loewenich FD, Liese J, Peschel A, Kretschmer D.

FASEB J. 2018 Jan;32(1):26-36. doi: 10.1096/fj.201700441R. Epub 2017 Aug 30.

12.

Influence of protein deficient diet, vitamin B[sub]2[/sub] supplementation and physical training on serum composition of polyunsaturated fatty acids (PUFAs) in rats.

Lewicka A, Lewicki S, Kłos A, Dębski B, Kurył T, Bertrandt J.

Ann Agric Environ Med. 2017 May 11;24(2):185-189. doi: 10.5604/12321966.1228391.

13.

[Health awareness and cooperation with the patient in the therapeutic process in a population of patients with chronic kidney disease in the center of Gdansk].

Heleniak Z, Cieplińska M, Szychliński T, Rychter D, Jagodzińska K, Kłos A, Kuźmiuk-Glembin I, Tylicki L, Rutkowski B, Dębska-Ślizień A.

Przegl Lek. 2017;74(2):71-5. Polish.

PMID:
29694009
14.

Nonsteroidal anti-inflammatory drug use in patients with chronic kidney disease.

Heleniak Z, Cieplińska M, Szychliński T, Rychter D, Jagodzińska K, Kłos A, Kuźmiuk I, Tylicka MJ, Tylicki L, Rutkowski B, Dębska-Ślizień A.

J Nephrol. 2017 Dec;30(6):781-786. doi: 10.1007/s40620-016-0352-z. Epub 2016 Sep 27.

15.

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C.

Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210.

16.

An optimized, fast-to-perform mouse lung infection model with the human pathogen Chlamydia trachomatis for in vivo screening of antibiotics, vaccine candidates and modified host-pathogen interactions.

Dutow P, Wask L, Bothe M, Fehlhaber B, Laudeley R, Rheinheimer C, Yang Z, Zhong G, Glage S, Klos A.

Pathog Dis. 2016 Mar;74(2). pii: ftv120. doi: 10.1093/femspd/ftv120. Epub 2015 Dec 15.

PMID:
26676260
17.

Differential Contributions of the Complement Anaphylotoxin Receptors C5aR1 and C5aR2 to the Early Innate Immune Response against Staphylococcus aureus Infection.

Horst SA, Itzek A, Klos A, Beineke A, Medina E.

Pathogens. 2015 Oct 23;4(4):722-38. doi: 10.3390/pathogens4040722.

18.

Severe pneumonia due to Parachlamydia acanthamoebae following intranasal inoculation: a mice model.

Pilloux L, Casson N, Sommer K, Klos A, Stehle JC, Pusztaszeri M, Greub G.

Microbes Infect. 2015 Nov-Dec;17(11-12):755-60. doi: 10.1016/j.micinf.2015.08.007. Epub 2015 Sep 1.

19.

Atheroprotective role of C5ar2 deficiency in apolipoprotein E-deficient mice.

Selle J, Asare Y, Köhncke J, Alampour-Rajabi S, Shagdarsuren G, Klos A, Weber C, Jankowski J, Shagdarsuren E.

Thromb Haemost. 2015 Oct;114(4):848-58. doi: 10.1160/TH14-12-1075. Epub 2015 Jun 18.

PMID:
26084965
20.

Temperature and host cell-dependent changes in virulence of Chlamydia pneumoniae CWL029 in an optimized mouse infection model.

Janik K, Bode J, Dutow P, Laudeley R, Geffers R, Sommer K, Glage S, Klos A.

Pathog Dis. 2015 Feb;73(1):1-8. doi: 10.1093/femspd/ftu001. Epub 2014 Dec 4.

PMID:
25853997
21.

DXD motif-dependent and -independent effects of the chlamydia trachomatis cytotoxin CT166.

Bothe M, Dutow P, Pich A, Genth H, Klos A.

Toxins (Basel). 2015 Feb 17;7(2):621-37. doi: 10.3390/toxins7020621.

22.

The activity concentration of post-Chernobyl ¹³⁷Cs in the area of the Opole Anomaly (southern Poland).

Wróbel Ł, Dołhańczuk-Śródka A, Kłos A, Ziembik Z.

Environ Monit Assess. 2015 Jan;187(1):4084. doi: 10.1007/s10661-014-4084-z. Epub 2014 Nov 12.

PMID:
25389020
23.

Influence of Military Training and Standardized Nutrition in Military Unit on Soldiers' Nutritional Status and Physical Fitness.

Tomczak A, Bertrandt J, Kłos A, Kłos K.

J Strength Cond Res. 2016 Oct;30(10):2774-80. doi: 10.1519/JSC.0000000000000716.

PMID:
25268293
24.

Chlamydia psittaci: new insights into genomic diversity, clinical pathology, host-pathogen interaction and anti-bacterial immunity.

Knittler MR, Berndt A, Böcker S, Dutow P, Hänel F, Heuer D, Kägebein D, Klos A, Koch S, Liebler-Tenorio E, Ostermann C, Reinhold P, Saluz HP, Schöfl G, Sehnert P, Sachse K.

Int J Med Microbiol. 2014 Oct;304(7):877-93. doi: 10.1016/j.ijmm.2014.06.010. Epub 2014 Jun 28. Review.

25.

Structural and functional characterization of human and murine C5a anaphylatoxins.

Schatz-Jakobsen JA, Yatime L, Larsen C, Petersen SV, Klos A, Andersen GR.

Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1704-17. doi: 10.1107/S139900471400844X. Epub 2014 May 30.

26.

Complement factor C5 but not C3 contributes significantly to hydrosalpinx development in mice infected with Chlamydia muridarum.

Yang Z, Conrad T, Zhou Z, Chen J, Dutow P, Klos A, Zhong G.

Infect Immun. 2014 Aug;82(8):3154-63. doi: 10.1128/IAI.01833-14. Epub 2014 May 19.

27.

C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.

Croker DE, Halai R, Kaeslin G, Wende E, Fehlhaber B, Klos A, Monk PN, Cooper MA.

Immunol Cell Biol. 2014 Aug;92(7):631-9. doi: 10.1038/icb.2014.32. Epub 2014 Apr 29.

28.

Role of capsule and suilysin in mucosal infection of complement-deficient mice with Streptococcus suis.

Seitz M, Beineke A, Singpiel A, Willenborg J, Dutow P, Goethe R, Valentin-Weigand P, Klos A, Baums CG.

Infect Immun. 2014 Jun;82(6):2460-71. doi: 10.1128/IAI.00080-14. Epub 2014 Mar 31.

29.

Sorption of cadmium and zinc in selected species of epigeic mosses.

Kłos A, Gordzielik E, Jóźwiak MA, Rajfur M.

Bull Environ Contam Toxicol. 2014 Mar;92(3):323-8. doi: 10.1007/s00128-014-1210-0. Epub 2014 Jan 28.

30.

The influence of vitamin B12 supplementation on the level of white blood cells and lymphocytes phenotype in rats fed a low-protein diet.

Lewicki S, Lewicka A, Kalicki B, Kłos A, Bertrandt J, Zdanowski R.

Cent Eur J Immunol. 2014;39(4):419-25. doi: 10.5114/ceji.2014.47723. Epub 2014 Dec 15.

31.

Histamine induces chemotaxis and phagocytosis in murine bone marrow-derived macrophages and RAW 264.7 macrophage-like cells via histamine H4-receptor.

Czerner CP, Klos A, Seifert R, Neumann D.

Inflamm Res. 2014 Mar;63(3):239-47. doi: 10.1007/s00011-013-0694-0. Epub 2013 Dec 8.

PMID:
24316866
32.

The complement C3a receptor is critical in defense against Chlamydia psittaci in mouse lung infection and required for antibody and optimal T cell response.

Dutow P, Fehlhaber B, Bode J, Laudeley R, Rheinheimer C, Glage S, Wetsel RA, Pabst O, Klos A.

J Infect Dis. 2014 Apr 15;209(8):1269-78. doi: 10.1093/infdis/jit640. Epub 2013 Nov 23.

33.

Sorption of heavy metals in the biomass of alga Palmaria palmata.

Rajfur M, Kłos A.

Water Sci Technol. 2013;68(7):1543-9. doi: 10.2166/wst.2013.400.

PMID:
24135103
34.

The impact of candle burning during All Saints' Day ceremonies on ambient alkyl-substituted benzene concentrations.

Olszowski T, Kłos A.

Bull Environ Contam Toxicol. 2013 Nov;91(5):588-94. doi: 10.1007/s00128-013-1104-6. Epub 2013 Sep 20.

36.

Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor.

Glatzer F, Gschwandtner M, Ehling S, Rossbach K, Janik K, Klos A, Bäumer W, Kietzmann M, Werfel T, Gutzmer R.

J Allergy Clin Immunol. 2013 Dec;132(6):1358-67. doi: 10.1016/j.jaci.2013.06.023. Epub 2013 Aug 9.

37.

Severity of allergic airway disease due to house dust mite allergen is not increased after clinical recovery of lung infection with Chlamydia pneumoniae in mice.

Dutow P, Lingner S, Laudeley R, Glage S, Hoymann HG, Dittrich AM, Fehlhaber B, Müller M, Braun A, Klos A.

Infect Immun. 2013 Sep;81(9):3366-74. doi: 10.1128/IAI.00334-13. Epub 2013 Jul 1.

38.

The complement anaphylatoxin C3a receptor (C3aR) contributes to the inflammatory response in dextran sulfate sodium (DSS)-induced colitis in mice.

Wende E, Laudeley R, Bleich A, Bleich E, Wetsel RA, Glage S, Klos A.

PLoS One. 2013 Apr 26;8(4):e62257. doi: 10.1371/journal.pone.0062257. Print 2013.

39.

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors.

Klos A, Wende E, Wareham KJ, Monk PN.

Pharmacol Rev. 2013 Jan;65(1):500-43. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):466.

PMID:
23383423
40.

Physical fitness and nutritional status of polish ground force unit recruits.

Tomczak A, Bertrandt J, Kłos A.

Biol Sport. 2012 Dec;29(4):277-80. doi: 10.5604/20831862.1019665. Epub 2012 Nov 15.

41.

A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci.

Bode J, Dutow P, Sommer K, Janik K, Glage S, Tümmler B, Munder A, Laudeley R, Sachse KW, Klos A.

PLoS One. 2012;7(11):e50327. doi: 10.1371/journal.pone.0050327. Epub 2012 Nov 26.

42.

Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.

Bajic G, Yatime L, Klos A, Andersen GR.

Protein Sci. 2013 Feb;22(2):204-12. doi: 10.1002/pro.2200. Epub 2012 Dec 16.

43.

4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.

Pechulis AD, Beck JP, Curry MA, Wolf MA, Harms AE, Xi N, Opalka C, Sweet MP, Yang Z, Vellekoop AS, Klos AM, Crocker PJ, Hassler C, Laws M, Kitchen DB, Smith MA, Olson RE, Liu S, Molino BF.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7219-22. doi: 10.1016/j.bmcl.2012.09.050. Epub 2012 Sep 25.

PMID:
23084899
44.

Phosphorylation of C3a receptor at multiple sites mediates desensitization, β-arrestin-2 recruitment and inhibition of NF-κB activity in mast cells.

Gupta K, Subramanian H, Klos A, Ali H.

PLoS One. 2012;7(10):e46369. doi: 10.1371/journal.pone.0046369. Epub 2012 Oct 15.

45.

Mechanisms for Translocation of Heavy Metals from Soil to Epigeal Mosses.

Kłos A, Czora M, Rajfur M, Wacławek M.

Water Air Soil Pollut. 2012 May;223(4):1829-1836. Epub 2011 Oct 11.

46.

Sorption of copper(II) ions in the biomass of alga Spirogyra sp.

Rajfur M, Kłos A, Wacławek M.

Bioelectrochemistry. 2012 Oct;87:65-70. doi: 10.1016/j.bioelechem.2011.12.007. Epub 2011 Dec 30.

PMID:
22245248
47.

Use of Lichen and Moss in Assessment of Forest Contamination with Heavy Metals in Praded and Glacensis Euroregions (Poland and Czech Republic).

Kłos A, Rajfur M, Srámek I, Wacławek M.

Water Air Soil Pollut. 2011 Nov;222(1-4):367-376. Epub 2011 May 27.

48.

Mercury concentration in lichen, moss and soil samples collected from the forest areas of Praded and Glacensis Euroregions (Poland and Czech Republic).

Kłos A, Rajfur M, Šrámek I, Wacławek M.

Environ Monit Assess. 2012 Nov;184(11):6765-74. doi: 10.1007/s10661-011-2456-1. Epub 2011 Dec 2.

49.

Algae utilization in assessment of the large Turawa Lake (Poland) pollution with heavy metals.

Rajfur M, Kłos A, Wacławek M.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2011;46(12):1401-8. doi: 10.1080/10934529.2011.606717.

PMID:
21942393
50.

Distinct different contributions of the alternative and classical complement activation pathway for the innate host response during sepsis.

Dahlke K, Wrann CD, Sommerfeld O, Sossdorf M, Recknagel P, Sachse S, Winter SW, Klos A, Stahl GL, Ma YX, Claus RA, Reinhart K, Bauer M, Riedemann NC.

J Immunol. 2011 Mar 1;186(5):3066-75. doi: 10.4049/jimmunol.1002741. Epub 2011 Jan 24.

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