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Items: 1 to 50 of 82

1.

Stabilizing Techniques and Guided Imagery for Traumatized Male Refugees in a German State Registration and Reception Center: A Qualitative Study on a Psychotherapeutic Group Intervention.

Zehetmair C, Tegeler I, Kaufmann C, Klippel A, Reddemann L, Junne F, Herpertz SC, Friederich HC, Nikendei C.

J Clin Med. 2019 Jun 22;8(6). pii: E894. doi: 10.3390/jcm8060894.

2.

Acquisition and transfer of spatial knowledge during wayfinding.

He Q, McNamara TP, Bodenheimer B, Klippel A.

J Exp Psychol Learn Mem Cogn. 2019 Aug;45(8):1364-1386. doi: 10.1037/xlm0000654. Epub 2018 Aug 20.

PMID:
30124310
3.

Sensitivity to Peer Evaluation and Its Genetic and Environmental Determinants: Findings from a Population-Based Twin Study.

Klippel A, Reininghaus U, Viechtbauer W, Decoster J, Delespaul P, Derom C, de Hert M, Jacobs N, Menne-Lothmann C, Rutten B, Thiery E, van Os J, van Winkel R, Myin-Germeys I, Wichers M.

Child Psychiatry Hum Dev. 2018 Oct;49(5):766-778. doi: 10.1007/s10578-018-0792-x.

4.

The Impact of Treatments for Depression on the Dynamic Network Structure of Mental States: Two Randomized Controlled Trials.

Snippe E, Viechtbauer W, Geschwind N, Klippel A, de Jonge P, Wichers M.

Sci Rep. 2017 Apr 20;7:46523. doi: 10.1038/srep46523.

5.

The Cascade of Stress: A Network Approach to Explore Differential Dynamics in Populations Varying in Risk for Psychosis.

Klippel A, Viechtbauer W, Reininghaus U, Wigman J, van Borkulo C; MERGE, Myin-Germeys I, Wichers M.

Schizophr Bull. 2018 Feb 15;44(2):328-337. doi: 10.1093/schbul/sbx037.

6.

Modeling the Interplay Between Psychological Processes and Adverse, Stressful Contexts and Experiences in Pathways to Psychosis: An Experience Sampling Study.

Klippel A, Myin-Germeys I, Chavez-Baldini U, Preacher KJ, Kempton M, Valmaggia L, Calem M, So S, Beards S, Hubbard K, Gayer-Anderson C, Onyejiaka A, Wichers M, McGuire P, Murray R, Garety P, van Os J, Wykes T, Morgan C, Reininghaus U.

Schizophr Bull. 2017 Mar 1;43(2):302-315. doi: 10.1093/schbul/sbw185. Erratum in: Schizophr Bull. 2018 Aug 20;44(5):1159-1165.

7.

Ecological momentary interventions in psychiatry.

Myin-Germeys I, Klippel A, Steinhart H, Reininghaus U.

Curr Opin Psychiatry. 2016 Jul;29(4):258-63. doi: 10.1097/YCO.0000000000000255. Review.

PMID:
27153125
8.

Rate of CRL4(CRBN) substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4.

Bjorklund CC, Lu L, Kang J, Hagner PR, Havens CG, Amatangelo M, Wang M, Ren Y, Couto S, Breider M, Ning Y, Gandhi AK, Daniel TO, Chopra R, Klippel A, Thakurta AG.

Blood Cancer J. 2015 Oct 2;5:e354. doi: 10.1038/bcj.2015.66.

9.

Using DNA Barcodes to Identify Road-Killed Animals in Two Atlantic Forest Nature Reserves, Brazil.

Klippel AH, Oliveira PV, Britto KB, Freire BF, Moreno MR, Dos Santos AR, Banhos A, Paneto GG.

PLoS One. 2015 Aug 5;10(8):e0134877. doi: 10.1371/journal.pone.0134877. eCollection 2015.

10.

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL.

Hagner PR, Man HW, Fontanillo C, Wang M, Couto S, Breider M, Bjorklund C, Havens CG, Lu G, Rychak E, Raymon H, Narla RK, Barnes L, Khambatta G, Chiu H, Kosek J, Kang J, Amantangelo MD, Waldman M, Lopez-Girona A, Cai T, Pourdehnad M, Trotter M, Daniel TO, Schafer PH, Klippel A, Thakurta A, Chopra R, Gandhi AK.

Blood. 2015 Aug 6;126(6):779-89. doi: 10.1182/blood-2015-02-628669. Epub 2015 May 22.

11.

Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH2.

Dann SG, Ryskin M, Barsotti AM, Golas J, Shi C, Miranda M, Hosselet C, Lemon L, Lucas J, Karnoub M, Wang F, Myers JS, Garza SJ, Follettie MT, Geles KG, Klippel A, Rollins RA, Fantin VR.

EMBO J. 2015 Jul 2;34(13):1773-85. doi: 10.15252/embj.201488166. Epub 2015 May 15.

12.

Exploring the underlying structure of mental disorders: cross-diagnostic differences and similarities from a network perspective using both a top-down and a bottom-up approach.

Wigman JT, van Os J, Borsboom D, Wardenaar KJ, Epskamp S, Klippel A; MERGE, Viechtbauer W, Myin-Germeys I, Wichers M.

Psychol Med. 2015 Aug;45(11):2375-87. doi: 10.1017/S0033291715000331. Epub 2015 Mar 25.

PMID:
25804221
13.

Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

Falk MD, Liu W, Bolaños B, Unsal-Kacmaz K, Klippel A, Grant S, Brooun A, Timofeevski S.

Biosci Rep. 2014 Apr 1;34(2). pii: e00097. Print 2014 Apr 1.

14.

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

Gandhi AK, Kang J, Havens CG, Conklin T, Ning Y, Wu L, Ito T, Ando H, Waldman MF, Thakurta A, Klippel A, Handa H, Daniel TO, Schafer PH, Chopra R.

Br J Haematol. 2014 Mar;164(6):811-21. doi: 10.1111/bjh.12708. Epub 2013 Dec 13.

15.

p120 catenin is a key effector of a Ras-PKCɛ oncogenic signaling axis.

Dann SG, Golas J, Miranda M, Shi C, Wu J, Jin G, Rosfjord E, Upeslacis E, Klippel A.

Oncogene. 2014 Mar 13;33(11):1385-94. doi: 10.1038/onc.2013.91. Epub 2013 Apr 1.

PMID:
23542175
16.

Formally grounding spatio-temporal thinking.

Klippel A, Wallgrün JO, Yang J, Li R, Dylla F.

Cogn Process. 2012 Aug;13 Suppl 1:S209-14. doi: 10.1007/s10339-012-0451-2. Review.

PMID:
22806649
17.

The interaction of PKN3 with RhoC promotes malignant growth.

Unsal-Kacmaz K, Ragunathan S, Rosfjord E, Dann S, Upeslacis E, Grillo M, Hernandez R, Mack F, Klippel A.

Mol Oncol. 2012 Jun;6(3):284-98. doi: 10.1016/j.molonc.2011.12.001. Epub 2011 Dec 28.

18.

Movement choremes: bridging cognitive understanding and formal characterizations of movement patterns(1.).

Klippel A.

Top Cogn Sci. 2011 Oct;3(4):722-40. doi: 10.1111/j.1756-8765.2011.01159.x.

19.

Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor.

Nagashima K, Shumway SD, Sathyanarayanan S, Chen AH, Dolinski B, Xu Y, Keilhack H, Nguyen T, Wiznerowicz M, Li L, Lutterbach BA, Chi A, Paweletz C, Allison T, Yan Y, Munshi SK, Klippel A, Kraus M, Bobkova EV, Deshmukh S, Xu Z, Mueller U, Szewczak AA, Pan BS, Richon V, Pollock R, Blume-Jensen P, Northrup A, Andersen JN.

J Biol Chem. 2011 Feb 25;286(8):6433-48. doi: 10.1074/jbc.M110.156463. Epub 2010 Nov 30.

20.

Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells.

Dzwonek J, Preobrazhenska O, Cazzola S, Conidi A, Schellens A, van Dinther M, Stubbs A, Klippel A, Huylebroeck D, ten Dijke P, Verschueren K.

Mol Cancer Res. 2009 Aug;7(8):1342-53. doi: 10.1158/1541-7786.MCR-08-0558. Epub 2009 Aug 11.

21.

Human factors in GIScience laboratory at the Pennsylvania State University.

Klippel A.

Cogn Process. 2009 May;10(2):175-83. doi: 10.1007/s10339-008-0251-x. Epub 2009 Jan 10.

PMID:
19137344
22.

Peroxiredoxin 6 is required for blood vessel integrity in wounded skin.

Kümin A, Schäfer M, Epp N, Bugnon P, Born-Berclaz C, Oxenius A, Klippel A, Bloch W, Werner S.

J Cell Biol. 2007 Nov 19;179(4):747-60.

23.

Quantifying the usefulness of CT in evaluating seniors with abdominal pain.

Lewis LM, Klippel AP, Bavolek RA, Ross LM, Scherer TM, Banet GA.

Eur J Radiol. 2007 Feb;61(2):290-6. Epub 2006 Nov 7.

PMID:
17085004
24.

Regulation of epidermal homeostasis and repair by phosphoinositide 3-kinase.

Pankow S, Bamberger C, Klippel A, Werner S.

J Cell Sci. 2006 Oct 1;119(Pt 19):4033-46. Epub 2006 Sep 12.

25.

A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium.

Santel A, Aleku M, Keil O, Endruschat J, Esche V, Fisch G, Dames S, Löffler K, Fechtner M, Arnold W, Giese K, Klippel A, Kaufmann J.

Gene Ther. 2006 Aug;13(16):1222-34. Epub 2006 Apr 20.

PMID:
16625243
26.

RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy.

Santel A, Aleku M, Keil O, Endruschat J, Esche V, Durieux B, Löffler K, Fechtner M, Röhl T, Fisch G, Dames S, Arnold W, Giese K, Klippel A, Kaufmann J.

Gene Ther. 2006 Sep;13(18):1360-70. Epub 2006 Apr 20.

PMID:
16625242
27.

TRB3 is a PI 3-kinase dependent indicator for nutrient starvation.

Schwarzer R, Dames S, Tondera D, Klippel A, Kaufmann J.

Cell Signal. 2006 Jun;18(6):899-909. Epub 2005 Aug 29.

PMID:
16129579
28.

REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

Schwarzer R, Tondera D, Arnold W, Giese K, Klippel A, Kaufmann J.

Oncogene. 2005 Feb 10;24(7):1138-49.

PMID:
15592522
29.

PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.

Leenders F, Möpert K, Schmiedeknecht A, Santel A, Czauderna F, Aleku M, Penschuck S, Dames S, Sternberger M, Röhl T, Wellmann A, Arnold W, Giese K, Kaufmann J, Klippel A.

EMBO J. 2004 Aug 18;23(16):3303-13. Epub 2004 Jul 29.

30.

Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis.

Tondera D, Santel A, Schwarzer R, Dames S, Giese K, Klippel A, Kaufmann J.

J Biol Chem. 2004 Jul 23;279(30):31544-55. Epub 2004 May 20.

31.

Identification of novel effectors of invasive cell growth downstream of phosphoinositide 3-kinase.

Kaufmann J, Pronk G, Giese K, Klippel A.

Biochem Soc Trans. 2004 Apr;32(Pt 2):355-9. Review.

PMID:
15046608
32.

Inducible shRNA expression for application in a prostate cancer mouse model.

Czauderna F, Santel A, Hinz M, Fechtner M, Durieux B, Fisch G, Leenders F, Arnold W, Giese K, Klippel A, Kaufmann J.

Nucleic Acids Res. 2003 Nov 1;31(21):e127.

33.

Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4.

Kretschmer A, Moepert K, Dames S, Sternberger M, Kaufmann J, Klippel A.

Oncogene. 2003 Oct 2;22(43):6748-63.

PMID:
14555988
34.

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells.

Czauderna F, Fechtner M, Dames S, Aygün H, Klippel A, Pronk GJ, Giese K, Kaufmann J.

Nucleic Acids Res. 2003 Jun 1;31(11):2705-16.

35.

Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.

Czauderna F, Fechtner M, Aygün H, Arnold W, Klippel A, Giese K, Kaufmann J.

Nucleic Acids Res. 2003 Jan 15;31(2):670-82.

36.

GeneBlocs are powerful tools to study and delineate signal transduction processes that regulate cell growth and transformation.

Sternberger M, Schmiedeknecht A, Kretschmer A, Gebhardt F, Leenders F, Czauderna F, Von Carlowitz I, Engle M, Giese K, Beigelman L, Klippel A.

Antisense Nucleic Acid Drug Dev. 2002 Jun;12(3):131-43.

PMID:
12162696
37.

Unravelling novel intracellular pathways in cell-based assays.

Giese K, Kaufmann J, Pronk GJ, Klippel A.

Drug Discov Today. 2002 Feb 1;7(3):179-86. Review.

PMID:
11815234
38.

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

Krappmann D, Hatada EN, Tegethoff S, Li J, Klippel A, Giese K, Baeuerle PA, Scheidereit C.

J Biol Chem. 2000 Sep 22;275(38):29779-87.

39.

Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions.

Burow ME, Weldon CB, Collins-Burow BM, Ramsey N, McKee A, Klippel A, McLachlan JA, Clejan S, Beckman BS.

J Biol Chem. 2000 Mar 31;275(13):9628-35.

40.
41.

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation.

Klippel A, Escobedo MA, Wachowicz MS, Apell G, Brown TW, Giedlin MA, Kavanaugh WM, Williams LT.

Mol Cell Biol. 1998 Oct;18(10):5699-711.

42.
43.
44.

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons.

Philpott KL, McCarthy MJ, Klippel A, Rubin LL.

J Cell Biol. 1997 Nov 3;139(3):809-15.

45.

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis.

Kothakota S, Azuma T, Reinhard C, Klippel A, Tang J, Chu K, McGarry TJ, Kirschner MW, Koths K, Kwiatkowski DJ, Williams LT.

Science. 1997 Oct 10;278(5336):294-8.

46.

SIP/SHIP inhibits Xenopus oocyte maturation induced by insulin and phosphatidylinositol 3-kinase.

Deuter-Reinhard M, Apell G, Pot D, Klippel A, Williams LT, Kavanaugh WM.

Mol Cell Biol. 1997 May;17(5):2559-65.

47.
48.
49.

Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown.

Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM.

Endocrinology. 1996 Nov;137(11):5045-54.

PMID:
8895379
50.

Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes.

Tanti JF, Grémeaux T, Grillo S, Calleja V, Klippel A, Williams LT, Van Obberghen E, Le Marchand-Brustel Y.

J Biol Chem. 1996 Oct 11;271(41):25227-32.

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