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Items: 1 to 50 of 446

1.

A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade.

Zheng Y, Qiu Y, Grace CRR, Liu X, Klionsky DJ, Schulman BA.

Nat Commun. 2019 Aug 9;10(1):3600. doi: 10.1038/s41467-019-11435-y.

2.

TEX264 is a major receptor for mammalian reticulophagy.

Delorme-Axford E, Popelka H, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1677-1681. doi: 10.1080/15548627.2019.1646540. Epub 2019 Jul 30.

PMID:
31362563
3.

Clockophagy is a novel selective autophagy process favoring ferroptosis.

Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Sci Adv. 2019 Jul 24;5(7):eaaw2238. doi: 10.1126/sciadv.aaw2238. eCollection 2019 Jul.

4.

The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain.

Gatica D, Damasio A, Pascual C, Klionsky DJ, Ragusa MJ, Popelka H.

Autophagy. 2019 Aug 2:1-14. doi: 10.1080/15548627.2019.1648117. [Epub ahead of print]

PMID:
31352862
5.

Gene essentiality of Tubgcp4: dosage effect and autophagy regulation in retinal photoreceptors.

Xu X, Shang D, Cheng H, Klionsky DJ, Zhou R.

Autophagy. 2019 Oct;15(10):1834-1837. doi: 10.1080/15548627.2019.1647023. Epub 2019 Jul 29.

PMID:
31345090
6.

Found art: the yeast vacuole.

Hartley S, Klionsky DJ.

Autophagy. 2019 Sep;15(9):1638-1644. doi: 10.1080/15548627.2019.1638208. Epub 2019 Jul 15.

PMID:
31305202
7.

The "found-art vacuole"-people learn in different ways.

Klionsky DJ.

Autophagy. 2019 Sep;15(9):1493-1494. doi: 10.1080/15548627.2019.1630225. Epub 2019 Jun 25.

PMID:
31238790
8.

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Liu M, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Weaver J, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, Mizushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Shen HM, Simonsen A, Tooze SA, Vaccaro M, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1829-1833. doi: 10.1080/15548627.2019.1634444. Epub 2019 Jul 15.

PMID:
31234750
9.

2020 Is not that far away, which means it is time for the new guidelines.

Klionsky DJ.

Autophagy. 2019 Jul;15(7):1129. doi: 10.1080/15548627.2019.1624415. Epub 2019 May 31. No abstract available.

PMID:
31149865
10.

Bidirectional roles of Dhh1 in regulating autophagy.

Liu X, Jin M, Yao Z, Bernard A, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1838-1839. doi: 10.1080/15548627.2019.1621632. Epub 2019 Jun 11.

PMID:
31116636
11.

UIM-UDS: a new interface between ATG8 and its interactors.

Lei Y, Klionsky DJ.

Cell Res. 2019 Jul;29(7):507-508. doi: 10.1038/s41422-019-0179-y. No abstract available.

PMID:
31110250
12.

Dhh1 promotes autophagy-related protein translation during nitrogen starvation.

Liu X, Yao Z, Jin M, Namkoong S, Yin Z, Lee JH, Klionsky DJ.

PLoS Biol. 2019 Apr 11;17(4):e3000219. doi: 10.1371/journal.pbio.3000219. eCollection 2019 Apr.

13.

Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism.

Lahiri V, Hawkins WD, Klionsky DJ.

Cell Metab. 2019 Apr 2;29(4):803-826. doi: 10.1016/j.cmet.2019.03.003. Review.

PMID:
30943392
14.

The Pat1-Lsm complex prevents 3' to 5' degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy.

Gatica D, Hu G, Zhang N, Williamson PR, Klionsky DJ.

Autophagy. 2019 Apr;15(4):750-751. doi: 10.1080/15548627.2019.1587262. Epub 2019 Mar 18.

PMID:
30885034
15.

Ferroptosis is a type of autophagy-dependent cell death.

Zhou B, Liu J, Kang R, Klionsky DJ, Kroemer G, Tang D.

Semin Cancer Biol. 2019 Mar 14. pii: S1044-579X(19)30006-9. doi: 10.1016/j.semcancer.2019.03.002. [Epub ahead of print] Review.

PMID:
30880243
16.

Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy.

Gatica D, Klionsky DJ.

Curr Genet. 2019 Aug;65(4):847-849. doi: 10.1007/s00294-019-00943-5. Epub 2019 Feb 19. Review.

PMID:
30783742
17.

Podocytes and autophagy: a potential therapeutic target in lupus nephritis.

Zhou XJ, Klionsky DJ, Zhang H.

Autophagy. 2019 May;15(5):908-912. doi: 10.1080/15548627.2019.1580512. Epub 2019 Feb 17.

PMID:
30755075
18.

Follicular lymphoma-associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR.

Wang F, Gatica D, Ying ZX, Peterson LF, Kim P, Bernard D, Saiya-Cork K, Wang S, Kaminski MS, Chang AE, Phillips T, Klionsky DJ, Malek SN.

J Clin Invest. 2019 Mar 4;130:1626-1640. doi: 10.1172/JCI98288. eCollection 2019 Mar 4.

19.

Spatially distinct pools of TORC1 balance protein homeostasis.

Lahiri V, Klionsky DJ.

Autophagy. 2019 Apr;15(4):561-564. doi: 10.1080/15548627.2019.1575162. Epub 2019 Feb 6.

PMID:
30696339
20.

PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex.

Memisoglu G, Eapen VV, Yang Y, Klionsky DJ, Haber JE.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1613-1620. doi: 10.1073/pnas.1817078116. Epub 2019 Jan 17.

21.

Regulation of JMY's actin nucleation activity by TTC5/STRAP and LC3 during autophagy.

Liu X, Klionsky DJ.

Autophagy. 2019 Mar;15(3):373-374. doi: 10.1080/15548627.2018.1564417. Epub 2019 Jan 6.

PMID:
30593260
22.

On the edge of degradation: Autophagy regulation by RNA decay.

Delorme-Axford E, Klionsky DJ.

Wiley Interdiscip Rev RNA. 2019 May;10(3):e1522. doi: 10.1002/wrna.1522. Epub 2018 Dec 17. Review.

PMID:
30560575
23.

The Pat1-Lsm Complex Stabilizes ATG mRNA during Nitrogen Starvation-Induced Autophagy.

Gatica D, Hu G, Liu X, Zhang N, Williamson PR, Klionsky DJ.

Mol Cell. 2019 Jan 17;73(2):314-324.e4. doi: 10.1016/j.molcel.2018.11.002. Epub 2018 Dec 6.

PMID:
30527663
24.

Vacuolar hydrolysis and efflux: current knowledge and unanswered questions.

Parzych KR, Klionsky DJ.

Autophagy. 2019 Feb;15(2):212-227. doi: 10.1080/15548627.2018.1545821. Epub 2018 Nov 22.

PMID:
30422029
25.

Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain.

Delorme-Axford E, Klionsky DJ.

Autophagy. 2019 Jan;15(1):1-3. doi: 10.1080/15548627.2018.1539585. Epub 2018 Nov 1.

PMID:
30354937
26.

MAP1A/BLC3? Now I am really confused.

Klionsky DJ.

Autophagy. 2018;14(12):2033-2034. doi: 10.1080/15548627.2018.1528810. Epub 2018 Oct 9.

PMID:
30296899
27.

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity.

Kang R, Xie Y, Zeh HJ, Klionsky DJ, Tang D.

Autophagy. 2019 Jan;15(1):172-173. doi: 10.1080/15548627.2018.1526611. Epub 2018 Oct 8.

PMID:
30252570
28.

Structural basis for extremely strong binding affinity of giant ankyrins to LC3/GABARAP and its application in the inhibition of autophagy.

Popelka H, Klionsky DJ.

Autophagy. 2018;14(11):1847-1849. doi: 10.1080/15548627.2018.1522884.

PMID:
30231788
29.

Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles.

Mohammadinejad R, Moosavi MA, Tavakol S, Vardar DÖ, Hosseini A, Rahmati M, Dini L, Hussain S, Mandegary A, Klionsky DJ.

Autophagy. 2019 Jan;15(1):4-33. doi: 10.1080/15548627.2018.1509171. Epub 2018 Sep 13.

PMID:
30160607
30.

BECN1 is a new driver of ferroptosis.

Kang R, Zhu S, Zeh HJ, Klionsky DJ, Tang D.

Autophagy. 2018;14(12):2173-2175. doi: 10.1080/15548627.2018.1513758. Epub 2018 Sep 6.

PMID:
30145930
31.

Why do we need to regulate autophagy (and how can we do it)? A cartoon depiction.

Klionsky DJ.

Autophagy. 2018;14(10):1661-1664. doi: 10.1080/15548627.2018.1511218.

PMID:
30129812
32.

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.

Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, Wen Q, Xie Y, Liu J, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Dev Cell. 2018 Aug 20;46(4):441-455.e8. doi: 10.1016/j.devcel.2018.07.012. Epub 2018 Aug 9.

PMID:
30100261
33.

Finding a ribophagy receptor.

Jin M, Klionsky DJ.

Autophagy. 2018;14(9):1479-1480. doi: 10.1080/15548627.2018.1483672. Epub 2018 Aug 1.

34.

Plasmodium protein UIS3 protects the parasite from autophagy clearance.

Yao Z, Klionsky DJ.

Autophagy. 2018;14(8):1291-1292. doi: 10.1080/15548627.2018.1483671. Epub 2018 Aug 1.

35.

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.

Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7748-E7757. doi: 10.1073/pnas.1805784115. Epub 2018 Jul 31.

36.

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity.

Song X, Zhu S, Chen P, Hou W, Wen Q, Liu J, Xie Y, Liu J, Klionsky DJ, Kroemer G, Lotze MT, Zeh HJ, Kang R, Tang D.

Curr Biol. 2018 Aug 6;28(15):2388-2399.e5. doi: 10.1016/j.cub.2018.05.094. Epub 2018 Jul 26.

37.

The phagophore in four dimensions-a study in wood.

Sewell JC, Klionsky DJ.

Autophagy. 2018;14(10):1674-1676. doi: 10.1080/15548627.2018.1493315. Epub 2018 Aug 1.

38.

Inhibiting autophagy reduces retinal degeneration caused by protein misfolding.

Yao J, Qiu Y, Frontera E, Jia L, Khan NW, Klionsky DJ, Ferguson TA, Thompson DA, Zacks DN.

Autophagy. 2018;14(7):1226-1238. doi: 10.1080/15548627.2018.1463121. Epub 2018 Jul 13.

39.

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Hotamisligi G, Jäättelä M, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, MIzushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Simonsen A, Tooze S, Vaccaro MI, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2018;14(6):925-929. doi: 10.1080/15548627.2018.1465784.

40.

CCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis.

Lahiri V, Klionsky DJ.

Autophagy. 2018;14(7):1107-1109. doi: 10.1080/15548627.2018.1467199.

41.

An atypical BAR domain protein in autophagy.

Popelka H, Klionsky DJ, Ragusa MJ.

Autophagy. 2018;14(7):1155-1156. doi: 10.1080/15548627.2018.1445915. Epub 2018 May 25.

42.

Why do we need autophagy? A cartoon depiction.

Klionsky DJ.

Autophagy. 2018;14(5):739-742. doi: 10.1080/15548627.2018.1446628. Epub 2018 May 21.

43.

Genetic aberrations in macroautophagy genes leading to diseases.

van Beek N, Klionsky DJ, Reggiori F.

Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):803-816. doi: 10.1016/j.bbamcr.2018.03.002. Epub 2018 Mar 8. Review.

44.

A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae.

Parzych KR, Ariosa A, Mari M, Klionsky DJ.

Mol Biol Cell. 2018 May 1;29(9):1089-1099. doi: 10.1091/mbc.E17-08-0516. Epub 2018 Mar 22.

45.

Cargo recognition and degradation by selective autophagy.

Gatica D, Lahiri V, Klionsky DJ.

Nat Cell Biol. 2018 Mar;20(3):233-242. doi: 10.1038/s41556-018-0037-z. Epub 2018 Feb 23. Review.

46.

The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy.

Delorme-Axford E, Abernathy E, Lennemann NJ, Bernard A, Ariosa A, Coyne CB, Kirkegaard K, Klionsky DJ.

Autophagy. 2018;14(5):898-912. doi: 10.1080/15548627.2018.1441648. Epub 2018 Mar 21.

47.

Transcriptional and post-transcriptional regulation of autophagy in the yeast Saccharomyces cerevisiae.

Delorme-Axford E, Klionsky DJ.

J Biol Chem. 2018 Apr 13;293(15):5396-5403. doi: 10.1074/jbc.R117.804641. Epub 2018 Jan 25. Review.

48.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

49.

An Autophagy-Independent Role for ATG41 in Sulfur Metabolism During Zinc Deficiency.

Bucci MD, Weisenhorn E, Haws S, Yao Z, Zimmerman G, Gannon M, Taggart J, Lee T, Klionsky DJ, Russell J, Coon J, Eide DJ.

Genetics. 2018 Mar;208(3):1115-1130. doi: 10.1534/genetics.117.300679. Epub 2018 Jan 10.

50.

Autophagy and inflammation: A special review issue.

Deretic V, Klionsky DJ.

Autophagy. 2018;14(2):179-180. doi: 10.1080/15548627.2017.1412229. Epub 2018 Jan 29.

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