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Items: 1 to 50 of 458

1.

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein.

Dai E, Han L, Liu J, Xie Y, Kroemer G, Klionsky DJ, Zeh HJ, Kang R, Wang J, Tang D.

Autophagy. 2020 Jan 16:1-15. doi: 10.1080/15548627.2020.1714209. [Epub ahead of print]

PMID:
31920150
2.

Autophagy and disease: unanswered questions.

Yang Y, Klionsky DJ.

Cell Death Differ. 2020 Jan 3. doi: 10.1038/s41418-019-0480-9. [Epub ahead of print] Review.

PMID:
31900427
3.

The curious case of polyamines: spermidine drives reversal of B cell senescence.

Metur SP, Klionsky DJ.

Autophagy. 2019 Dec 3:1-2. doi: 10.1080/15548627.2019.1698210. [Epub ahead of print]

PMID:
31795807
4.

At a glance: A history of autophagy and cancer.

Wen X, Klionsky DJ.

Semin Cancer Biol. 2019 Nov 7. pii: S1044-579X(19)30167-1. doi: 10.1016/j.semcancer.2019.11.005. [Epub ahead of print] Review.

PMID:
31707087
5.

Allosteric regulation through a switch element in the autophagy E2, Atg3.

Qiu Y, Zheng Y, Grace CRR, Liu X, Klionsky DJ, Schulman BA.

Autophagy. 2020 Jan;16(1):183-184. doi: 10.1080/15548627.2019.1688550. Epub 2019 Nov 9.

PMID:
31690182
6.

On the relevance of precision autophagy flux control in vivo - Points of departure for clinical translation.

Loos B, Klionsky DJ, Du Toit A, Hofmeyr JS.

Autophagy. 2019 Nov 11:1-13. doi: 10.1080/15548627.2019.1687211. [Epub ahead of print]

PMID:
31679454
7.

Psp2, a novel regulator of autophagy that promotes autophagy-related protein translation.

Yin Z, Liu X, Ariosa A, Huang H, Jin M, Karbstein K, Klionsky DJ.

Cell Res. 2019 Dec;29(12):994-1008. doi: 10.1038/s41422-019-0246-4. Epub 2019 Oct 30.

PMID:
31666677
8.

How bacteria can block xenophagy: an insight from Salmonella.

Wen X, Klionsky DJ.

Autophagy. 2020 Feb;16(2):193-194. doi: 10.1080/15548627.2019.1666580. Epub 2019 Sep 18.

PMID:
31530078
9.

The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy.

Zheng L, Shu WJ, Li YM, Mari M, Yan C, Wang D, Yin ZH, Jiang W, Zhou Y, Okamoto K, Reggiori F, Klionsky DJ, Song Z, Du HN.

Autophagy. 2019 Sep 19:1-14. doi: 10.1080/15548627.2019.1668228. [Epub ahead of print]

PMID:
31525119
10.

A novel role of UBQLNs (ubiquilins) in regulating autophagy, MTOR signaling and v-ATPase function.

Yang Y, Klionsky DJ.

Autophagy. 2020 Jan;16(1):1-2. doi: 10.1080/15548627.2019.1665293. Epub 2019 Sep 13.

PMID:
31516068
11.

The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.

Wen X, Gatica D, Yin Z, Hu Z, Dengjel J, Klionsky DJ.

Autophagy. 2019 Sep 8:1-14. doi: 10.1080/15548627.2019.1659573. [Epub ahead of print]

PMID:
31462158
12.

Autophagic degradation of the circadian clock regulator promotes ferroptosis.

Liu J, Yang M, Kang R, Klionsky DJ, Tang D.

Autophagy. 2019 Nov;15(11):2033-2035. doi: 10.1080/15548627.2019.1659623. Epub 2019 Aug 26.

PMID:
31441366
13.

A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade.

Zheng Y, Qiu Y, Grace CRR, Liu X, Klionsky DJ, Schulman BA.

Nat Commun. 2019 Aug 9;10(1):3600. doi: 10.1038/s41467-019-11435-y.

14.

TEX264 is a major receptor for mammalian reticulophagy.

Delorme-Axford E, Popelka H, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1677-1681. doi: 10.1080/15548627.2019.1646540. Epub 2019 Jul 30.

PMID:
31362563
15.

Clockophagy is a novel selective autophagy process favoring ferroptosis.

Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Sci Adv. 2019 Jul 24;5(7):eaaw2238. doi: 10.1126/sciadv.aaw2238. eCollection 2019 Jul.

16.

The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain.

Gatica D, Damasio A, Pascual C, Klionsky DJ, Ragusa MJ, Popelka H.

Autophagy. 2019 Aug 2:1-14. doi: 10.1080/15548627.2019.1648117. [Epub ahead of print]

PMID:
31352862
17.

Gene essentiality of Tubgcp4: dosage effect and autophagy regulation in retinal photoreceptors.

Xu X, Shang D, Cheng H, Klionsky DJ, Zhou R.

Autophagy. 2019 Oct;15(10):1834-1837. doi: 10.1080/15548627.2019.1647023. Epub 2019 Jul 29.

PMID:
31345090
18.

Found art: the yeast vacuole.

Hartley S, Klionsky DJ.

Autophagy. 2019 Sep;15(9):1638-1644. doi: 10.1080/15548627.2019.1638208. Epub 2019 Jul 15.

PMID:
31305202
19.

The "found-art vacuole"-people learn in different ways.

Klionsky DJ.

Autophagy. 2019 Sep;15(9):1493-1494. doi: 10.1080/15548627.2019.1630225. Epub 2019 Jun 25.

PMID:
31238790
20.

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Liu M, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Weaver J, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, Mizushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Shen HM, Simonsen A, Tooze SA, Vaccaro M, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1829-1833. doi: 10.1080/15548627.2019.1634444. Epub 2019 Jul 15.

PMID:
31234750
21.

2020 Is not that far away, which means it is time for the new guidelines.

Klionsky DJ.

Autophagy. 2019 Jul;15(7):1129. doi: 10.1080/15548627.2019.1624415. Epub 2019 May 31. No abstract available.

PMID:
31149865
22.

Bidirectional roles of Dhh1 in regulating autophagy.

Liu X, Jin M, Yao Z, Bernard A, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1838-1839. doi: 10.1080/15548627.2019.1621632. Epub 2019 Jun 11.

PMID:
31116636
23.

UIM-UDS: a new interface between ATG8 and its interactors.

Lei Y, Klionsky DJ.

Cell Res. 2019 Jul;29(7):507-508. doi: 10.1038/s41422-019-0179-y. No abstract available.

PMID:
31110250
24.

Dhh1 promotes autophagy-related protein translation during nitrogen starvation.

Liu X, Yao Z, Jin M, Namkoong S, Yin Z, Lee JH, Klionsky DJ.

PLoS Biol. 2019 Apr 11;17(4):e3000219. doi: 10.1371/journal.pbio.3000219. eCollection 2019 Apr.

25.

Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism.

Lahiri V, Hawkins WD, Klionsky DJ.

Cell Metab. 2019 Apr 2;29(4):803-826. doi: 10.1016/j.cmet.2019.03.003. Review.

PMID:
30943392
26.

The Pat1-Lsm complex prevents 3' to 5' degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy.

Gatica D, Hu G, Zhang N, Williamson PR, Klionsky DJ.

Autophagy. 2019 Apr;15(4):750-751. doi: 10.1080/15548627.2019.1587262. Epub 2019 Mar 18.

PMID:
30885034
27.

Ferroptosis is a type of autophagy-dependent cell death.

Zhou B, Liu J, Kang R, Klionsky DJ, Kroemer G, Tang D.

Semin Cancer Biol. 2019 Mar 14. pii: S1044-579X(19)30006-9. doi: 10.1016/j.semcancer.2019.03.002. [Epub ahead of print] Review.

PMID:
30880243
28.

Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy.

Gatica D, Klionsky DJ.

Curr Genet. 2019 Aug;65(4):847-849. doi: 10.1007/s00294-019-00943-5. Epub 2019 Feb 19. Review.

PMID:
30783742
29.

Podocytes and autophagy: a potential therapeutic target in lupus nephritis.

Zhou XJ, Klionsky DJ, Zhang H.

Autophagy. 2019 May;15(5):908-912. doi: 10.1080/15548627.2019.1580512. Epub 2019 Feb 17.

PMID:
30755075
30.

Follicular lymphoma-associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR.

Wang F, Gatica D, Ying ZX, Peterson LF, Kim P, Bernard D, Saiya-Cork K, Wang S, Kaminski MS, Chang AE, Phillips T, Klionsky DJ, Malek SN.

J Clin Invest. 2019 Mar 4;130:1626-1640. doi: 10.1172/JCI98288. eCollection 2019 Mar 4.

31.

Spatially distinct pools of TORC1 balance protein homeostasis.

Lahiri V, Klionsky DJ.

Autophagy. 2019 Apr;15(4):561-564. doi: 10.1080/15548627.2019.1575162. Epub 2019 Feb 6.

PMID:
30696339
32.

PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex.

Memisoglu G, Eapen VV, Yang Y, Klionsky DJ, Haber JE.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1613-1620. doi: 10.1073/pnas.1817078116. Epub 2019 Jan 17.

33.

Regulation of JMY's actin nucleation activity by TTC5/STRAP and LC3 during autophagy.

Liu X, Klionsky DJ.

Autophagy. 2019 Mar;15(3):373-374. doi: 10.1080/15548627.2018.1564417. Epub 2019 Jan 6.

34.

On the edge of degradation: Autophagy regulation by RNA decay.

Delorme-Axford E, Klionsky DJ.

Wiley Interdiscip Rev RNA. 2019 May;10(3):e1522. doi: 10.1002/wrna.1522. Epub 2018 Dec 17. Review.

PMID:
30560575
35.

The Pat1-Lsm Complex Stabilizes ATG mRNA during Nitrogen Starvation-Induced Autophagy.

Gatica D, Hu G, Liu X, Zhang N, Williamson PR, Klionsky DJ.

Mol Cell. 2019 Jan 17;73(2):314-324.e4. doi: 10.1016/j.molcel.2018.11.002. Epub 2018 Dec 6.

36.

Vacuolar hydrolysis and efflux: current knowledge and unanswered questions.

Parzych KR, Klionsky DJ.

Autophagy. 2019 Feb;15(2):212-227. doi: 10.1080/15548627.2018.1545821. Epub 2018 Nov 22.

37.

Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain.

Delorme-Axford E, Klionsky DJ.

Autophagy. 2019 Jan;15(1):1-3. doi: 10.1080/15548627.2018.1539585. Epub 2018 Nov 1.

38.

MAP1A/BLC3? Now I am really confused.

Klionsky DJ.

Autophagy. 2018;14(12):2033-2034. doi: 10.1080/15548627.2018.1528810. Epub 2018 Oct 9.

PMID:
30296899
39.

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity.

Kang R, Xie Y, Zeh HJ, Klionsky DJ, Tang D.

Autophagy. 2019 Jan;15(1):172-173. doi: 10.1080/15548627.2018.1526611. Epub 2018 Oct 8.

40.
41.

Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles.

Mohammadinejad R, Moosavi MA, Tavakol S, Vardar DÖ, Hosseini A, Rahmati M, Dini L, Hussain S, Mandegary A, Klionsky DJ.

Autophagy. 2019 Jan;15(1):4-33. doi: 10.1080/15548627.2018.1509171. Epub 2018 Sep 13.

42.

BECN1 is a new driver of ferroptosis.

Kang R, Zhu S, Zeh HJ, Klionsky DJ, Tang D.

Autophagy. 2018;14(12):2173-2175. doi: 10.1080/15548627.2018.1513758. Epub 2018 Sep 6.

PMID:
30145930
43.

Why do we need to regulate autophagy (and how can we do it)? A cartoon depiction.

Klionsky DJ.

Autophagy. 2018;14(10):1661-1664. doi: 10.1080/15548627.2018.1511218.

44.

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.

Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, Wen Q, Xie Y, Liu J, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Dev Cell. 2018 Aug 20;46(4):441-455.e8. doi: 10.1016/j.devcel.2018.07.012. Epub 2018 Aug 9.

45.

Finding a ribophagy receptor.

Jin M, Klionsky DJ.

Autophagy. 2018;14(9):1479-1480. doi: 10.1080/15548627.2018.1483672. Epub 2018 Aug 1.

46.

Plasmodium protein UIS3 protects the parasite from autophagy clearance.

Yao Z, Klionsky DJ.

Autophagy. 2018;14(8):1291-1292. doi: 10.1080/15548627.2018.1483671. Epub 2018 Aug 1.

47.

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.

Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7748-E7757. doi: 10.1073/pnas.1805784115. Epub 2018 Jul 31.

48.

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity.

Song X, Zhu S, Chen P, Hou W, Wen Q, Liu J, Xie Y, Liu J, Klionsky DJ, Kroemer G, Lotze MT, Zeh HJ, Kang R, Tang D.

Curr Biol. 2018 Aug 6;28(15):2388-2399.e5. doi: 10.1016/j.cub.2018.05.094. Epub 2018 Jul 26.

49.

The phagophore in four dimensions-a study in wood.

Sewell JC, Klionsky DJ.

Autophagy. 2018;14(10):1674-1676. doi: 10.1080/15548627.2018.1493315. Epub 2018 Aug 1.

50.

Inhibiting autophagy reduces retinal degeneration caused by protein misfolding.

Yao J, Qiu Y, Frontera E, Jia L, Khan NW, Klionsky DJ, Ferguson TA, Thompson DA, Zacks DN.

Autophagy. 2018;14(7):1226-1238. doi: 10.1080/15548627.2018.1463121. Epub 2018 Jul 13.

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