Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 82

1.

FANTOM5 CAGE profiles of human and mouse samples.

Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, Nagao-Sato S, Nakazato K, Ninomiya N, Nishiyori-Sueki H, Noma S, Saijyo E, Saka A, Sakai M, Simon C, Suzuki N, Tagami M, Watanabe S, Yoshida S, Arner P, Axton RA, Babina M, Baillie JK, Barnett TC, Beckhouse AG, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Carlisle AJ, Clevers HC, Davis CA, Detmar M, Dohi T, Edge ASB, Edinger M, Ehrlund A, Ekwall K, Endoh M, Enomoto H, Eslami A, Fagiolini M, Fairbairn L, Farach-Carson MC, Faulkner GJ, Ferrai C, Fisher ME, Forrester LM, Fujita R, Furusawa JI, Geijtenbeek TB, Gingeras T, Goldowitz D, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Hasegawa Y, Herlyn M, Heutink P, Hitchens KJ, Hume DA, Ikawa T, Ishizu Y, Kai C, Kawamoto H, Kawamura YI, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klein S, Klinken SP, Knox AJ, Kojima S, Koseki H, Koyasu S, Lee W, Lennartsson A, Mackay-Sim A, Mejhert N, Mizuno Y, Morikawa H, Morimoto M, Moro K, Morris KJ, Motohashi H, Mummery CL, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nozaki T, Ogishima S, Ohkura N, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Passier R, Patrikakis M, Pombo A, Pradhan-Bhatt S, Qin XY, Rehli M, Rizzu P, Roy S, Sajantila A, Sakaguchi S, Sato H, Satoh H, Savvi S, Saxena A, Schmidl C, Schneider C, Schulze-Tanzil GG, Schwegmann A, Sheng G, Shin JW, Sugiyama D, Sugiyama T, Summers KM, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tomoiu A, Toyoda H, van de Wetering M, van den Berg LM, Verardo R, Vijayan D, Wells CA, Winteringham LN, Wolvetang E, Yamaguchi Y, Yamamoto M, Yanagi-Mizuochi C, Yoneda M, Yonekura Y, Zhang PG, Zucchelli S, Abugessaisa I, Arner E, Harshbarger J, Kondo A, Lassmann T, Lizio M, Sahin S, Sengstag T, Severin J, Shimoji H, Suzuki M, Suzuki H, Kawai J, Kondo N, Itoh M, Daub CO, Kasukawa T, Kawaji H, Carninci P, Forrest ARR, Hayashizaki Y.

Sci Data. 2017 Aug 29;4:170112. doi: 10.1038/sdata.2017.112.

2.

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Arner E, Daub CO, Vitting-Seerup K, Andersson R, Lilje B, Drabløs F, Lennartsson A, Rönnerblad M, Hrydziuszko O, Vitezic M, Freeman TC, Alhendi AM, Arner P, Axton R, Baillie JK, Beckhouse A, Bodega B, Briggs J, Brombacher F, Davis M, Detmar M, Ehrlund A, Endoh M, Eslami A, Fagiolini M, Fairbairn L, Faulkner GJ, Ferrai C, Fisher ME, Forrester L, Goldowitz D, Guler R, Ha T, Hara M, Herlyn M, Ikawa T, Kai C, Kawamoto H, Khachigian LM, Klinken SP, Kojima S, Koseki H, Klein S, Mejhert N, Miyaguchi K, Mizuno Y, Morimoto M, Morris KJ, Mummery C, Nakachi Y, Ogishima S, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov D, Passier R, Patrikakis M, Pombo A, Qin XY, Roy S, Sato H, Savvi S, Saxena A, Schwegmann A, Sugiyama D, Swoboda R, Tanaka H, Tomoiu A, Winteringham LN, Wolvetang E, Yanagi-Mizuochi C, Yoneda M, Zabierowski S, Zhang P, Abugessaisa I, Bertin N, Diehl AD, Fukuda S, Furuno M, Harshbarger J, Hasegawa A, Hori F, Ishikawa-Kato S, Ishizu Y, Itoh M, Kawashima T, Kojima M, Kondo N, Lizio M, Meehan TF, Mungall CJ, Murata M, Nishiyori-Sueki H, Sahin S, Nagao-Sato S, Severin J, de Hoon MJ, Kawai J, Kasukawa T, Lassmann T, Suzuki H, Kawaji H, Summers KM, Wells C; FANTOM Consortium, Hume DA, Forrest AR, Sandelin A, Carninci P, Hayashizaki Y.

Science. 2015 Feb 27;347(6225):1010-4. doi: 10.1126/science.1259418. Epub 2015 Feb 12.

3.

A promoter-level mammalian expression atlas.

FANTOM Consortium and the RIKEN PMI and CLST (DGT), Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, Bertin N, Jørgensen M, Dimont E, Arner E, Schmidl C, Schaefer U, Medvedeva YA, Plessy C, Vitezic M, Severin J, Semple C, Ishizu Y, Young RS, Francescatto M, Alam I, Albanese D, Altschuler GM, Arakawa T, Archer JA, Arner P, Babina M, Rennie S, Balwierz PJ, Beckhouse AG, Pradhan-Bhatt S, Blake JA, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Burroughs AM, Califano A, Cannistraci CV, Carbajo D, Chen Y, Chierici M, Ciani Y, Clevers HC, Dalla E, Davis CA, Detmar M, Diehl AD, Dohi T, Drabløs F, Edge AS, Edinger M, Ekwall K, Endoh M, Enomoto H, Fagiolini M, Fairbairn L, Fang H, Farach-Carson MC, Faulkner GJ, Favorov AV, Fisher ME, Frith MC, Fujita R, Fukuda S, Furlanello C, Furino M, Furusawa J, Geijtenbeek TB, Gibson AP, Gingeras T, Goldowitz D, Gough J, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Harbers M, Harshbarger J, Hasegawa A, Hasegawa Y, Hashimoto T, Herlyn M, Hitchens KJ, Ho Sui SJ, Hofmann OM, Hoof I, Hori F, Huminiecki L, Iida K, Ikawa T, Jankovic BR, Jia H, Joshi A, Jurman G, Kaczkowski B, Kai C, Kaida K, Kaiho A, Kajiyama K, Kanamori-Katayama M, Kasianov AS, Kasukawa T, Katayama S, Kato S, Kawaguchi S, Kawamoto H, Kawamura YI, Kawashima T, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klinken SP, Knox AJ, Kojima M, Kojima S, Kondo N, Koseki H, Koyasu S, Krampitz S, Kubosaki A, Kwon AT, Laros JF, Lee W, Lennartsson A, Li K, Lilje B, Lipovich L, Mackay-Sim A, Manabe R, Mar JC, Marchand B, Mathelier A, Mejhert N, Meynert A, Mizuno Y, de Lima Morais DA, Morikawa H, Morimoto M, Moro K, Motakis E, Motohashi H, Mummery CL, Murata M, Nagao-Sato S, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nakazato K, van Nimwegen E, Ninomiya N, Nishiyori H, Noma S, Noma S, Noazaki T, Ogishima S, Ohkura N, Ohimiya H, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Pain A, Passier R, Patrikakis M, Persson H, Piazza S, Prendergast JG, Rackham OJ, Ramilowski JA, Rashid M, Ravasi T, Rizzu P, Roncador M, Roy S, Rye MB, Saijyo E, Sajantila A, Saka A, Sakaguchi S, Sakai M, Sato H, Savvi S, Saxena A, Schneider C, Schultes EA, Schulze-Tanzil GG, Schwegmann A, Sengstag T, Sheng G, Shimoji H, Shimoni Y, Shin JW, Simon C, Sugiyama D, Sugiyama T, Suzuki M, Suzuki N, Swoboda RK, 't Hoen PA, Tagami M, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tatum Z, Thompson M, Toyodo H, Toyoda T, Valen E, van de Wetering M, van den Berg LM, Verado R, Vijayan D, Vorontsov IE, Wasserman WW, Watanabe S, Wells CA, Winteringham LN, Wolvetang E, Wood EJ, Yamaguchi Y, Yamamoto M, Yoneda M, Yonekura Y, Yoshida S, Zabierowski SE, Zhang PG, Zhao X, Zucchelli S, Summers KM, Suzuki H, Daub CO, Kawai J, Heutink P, Hide W, Freeman TC, Lenhard B, Bajic VB, Taylor MS, Makeev VJ, Sandelin A, Hume DA, Carninci P, Hayashizaki Y.

Nature. 2014 Mar 27;507(7493):462-70. doi: 10.1038/nature13182.

4.

Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival.

Slavova-Azmanova NS, Kucera N, Louw A, Satiaputra J, Handoko A, Singer P, Stone L, McCarthy DJ, Klinken SP, Hibbs ML, Ingley E.

Biochem J. 2014 May 1;459(3):455-66. doi: 10.1042/BJ20130903.

5.

Gain-of-function Lyn induces anemia: appropriate Lyn activity is essential for normal erythropoiesis and Epo receptor signaling.

Slavova-Azmanova NS, Kucera N, Satiaputra J, Stone L, Magno A, Maxwell MJ, Quilici C, Erber W, Klinken SP, Hibbs ML, Ingley E.

Blood. 2013 Jul 11;122(2):262-71. doi: 10.1182/blood-2012-10-463158. Epub 2013 May 21.

6.

Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation.

Samuels AL, Klinken SP, Ingley E.

Blood. 2009 Apr 16;113(16):3845-56. doi: 10.1182/blood-2008-04-153452. Epub 2008 Dec 8.

7.

Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state.

Williams NK, Lucet IS, Klinken SP, Ingley E, Rossjohn J.

J Biol Chem. 2009 Jan 2;284(1):284-91. doi: 10.1074/jbc.M807850200. Epub 2008 Nov 4.

8.

Erythroid defects in TRalpha-/- mice.

Kendrick TS, Payne CJ, Epis MR, Schneider JR, Leedman PJ, Klinken SP, Ingley E.

Blood. 2008 Mar 15;111(6):3245-8. doi: 10.1182/blood-2007-07-101105. Epub 2008 Jan 18.

9.

Hls5 regulated erythroid differentiation by modulating GATA-1 activity.

Endersby R, Majewski IJ, Winteringham L, Beaumont JG, Samuels A, Scaife R, Lim E, Crossley M, Klinken SP, Lalonde JP.

Blood. 2008 Feb 15;111(4):1946-50. Epub 2007 Dec 6.

10.

Myeloid leukemia factor 1 associates with a novel heterogeneous nuclear ribonucleoprotein U-like molecule.

Winteringham LN, Endersby R, Kobelke S, McCulloch RK, Williams JH, Stillitano J, Cornwall SM, Ingley E, Klinken SP.

J Biol Chem. 2006 Dec 15;281(50):38791-800. Epub 2006 Sep 28.

11.

Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.

Ingley E, Schneider JR, Payne CJ, McCarthy DJ, Harder KW, Hibbs ML, Klinken SP.

J Biol Chem. 2006 Oct 20;281(42):31920-9. Epub 2006 Aug 18.

12.

Cross-regulation of JAK and Src kinases.

Ingley E, Klinken SP.

Growth Factors. 2006 Mar;24(1):89-95. Review.

PMID:
16393697
13.

Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3.

Court NW, Ingley E, Klinken SP, Bogoyevitch MA.

Biochim Biophys Acta. 2005 May 15;1744(1):68-75. Epub 2004 Dec 31.

14.

Lyn deficiency reduces GATA-1, EKLF and STAT5, and induces extramedullary stress erythropoiesis.

Ingley E, McCarthy DJ, Pore JR, Sarna MK, Adenan AS, Wright MJ, Erber W, Tilbrook PA, Klinken SP.

Oncogene. 2005 Jan 13;24(3):336-43.

PMID:
15516974
15.

New insights into the regulation of erythroid cells.

Ingley E, Tilbrook PA, Klinken SP.

IUBMB Life. 2004 Apr;56(4):177-84. Review.

16.

Myeloid Leukemia Factor 1 inhibits erythropoietin-induced differentiation, cell cycle exit and p27Kip1 accumulation.

Winteringham LN, Kobelke S, Williams JH, Ingley E, Klinken SP.

Oncogene. 2004 Jun 24;23(29):5105-9.

PMID:
15122318
17.

HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor.

Lalonde JP, Lim R, Ingley E, Tilbrook PA, Thompson MJ, McCulloch R, Beaumont JG, Wicking C, Eyre HJ, Sutherland GR, Howe K, Solomon E, Williams JH, Klinken SP.

J Biol Chem. 2004 Feb 27;279(9):8181-9. Epub 2003 Dec 8.

18.

Differential regulation of SOCS genes in normal and transformed erythroid cells.

Sarna MK, Ingley E, Busfield SJ, Cull VS, Lepere W, McCarthy DJ, Wright MJ, Palmer GA, Chappell D, Sayer MS, Alexander WS, Hilton DJ, Starr R, Watowich SS, Bittorf T, Klinken SP, Tilbrook PA.

Oncogene. 2003 May 22;22(21):3221-30.

19.

Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells.

Greene WK, Ford J, Dixon D, Tilbrook PA, Watt PM, Klinken SP, Kees UR.

Br J Haematol. 2002 Sep;118(3):909-17.

PMID:
12181065
20.

MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.

Lim R, Winteringham LN, Williams JH, McCulloch RK, Ingley E, Tiao JY, Lalonde JP, Tsai S, Tilbrook PA, Sun Y, Wu X, Morris SW, Klinken SP.

J Biol Chem. 2002 Oct 25;277(43):40997-1008. Epub 2002 Aug 9.

21.

Erythropoietin-stimulated Raf-1 tyrosine phosphorylation is associated with the tyrosine kinase Lyn in J2E erythroleukemic cells.

Tilbrook PA, Colley SM, McCarthy DJ, Marais R, Klinken SP.

Arch Biochem Biophys. 2001 Dec 1;396(1):128-32.

PMID:
11716471
22.

Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells.

Ingley E, Chappell D, Poon SY, Sarna MK, Beaumont JG, Williams JH, Stillitano JP, Tsai S, Leedman PJ, Tilbrook PA, Klinken SP.

J Biol Chem. 2001 Nov 16;276(46):43428-34. Epub 2001 Sep 5.

23.

Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn.

Tilbrook PA, Palmer GA, Bittorf T, McCarthy DJ, Wright MJ, Sarna MK, Linnekin D, Cull VS, Williams JH, Ingley E, Schneider-Mergener J, Krystal G, Klinken SP.

Cancer Res. 2001 Mar 15;61(6):2453-8.

24.

Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells.

Sayer MS, Tilbrook PA, Spadaccini A, Ingley E, Sarna MK, Williams JH, Andrews NC, Klinken SP.

J Biol Chem. 2000 Aug 18;275(33):25292-8.

25.

Karyotypic abnormalities associated with haemopoietic lineage switching are not linked with mutations to p53.

Colley SM, Chappell DS, Busfield SJ, Voon DC, Klinken SP.

Int J Biochem Cell Biol. 2000 May;32(5):509-17.

PMID:
10736566
26.

HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells.

Ingley E, Sarna MK, Beaumont JG, Tilbrook PA, Tsai S, Takemoto Y, Williams JH, Klinken SP.

J Biol Chem. 2000 Mar 17;275(11):7887-93.

27.

Dominant action of mutated erythropoietin receptors on differentiation in vitro and erythroleukemia development in vivo.

Cull V, Tilbrook PA, Adenan AS, Chappell D, Ingley E, Sarna MK, Palmer TN, Watowich SS, Klinken SP.

Oncogene. 2000 Feb 17;19(7):953-60.

28.

Plasticity in the haemopoietic system.

Williams JH, Klinken SP.

Int J Biochem Cell Biol. 1999 Oct;31(10):1237-42. Review. No abstract available.

PMID:
10582350
29.

The erythropoietin receptor.

Tilbrook PA, Klinken SP.

Int J Biochem Cell Biol. 1999 Oct;31(10):1001-5. Review.

PMID:
10582333
30.

Regulation of hemopoietic system.

Klinken SP.

Int J Biochem Cell Biol. 1999 Oct;31(10):983-9.

PMID:
10582330
31.

HLS7, a hemopoietic lineage switch gene homologous to the leukemia-inducing gene MLF1.

Williams JH, Daly LN, Ingley E, Beaumont JG, Tilbrook PA, Lalonde JP, Stillitano JP, Klinken SP.

EMBO J. 1999 Oct 15;18(20):5559-66.

32.

A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.

Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP.

FEBS Lett. 1999 Oct 1;459(1):69-74.

33.

Erythropoietin and erythropoietin receptor.

Tilbrook PA, Klinken SP.

Growth Factors. 1999;17(1):25-35. Review. No abstract available.

PMID:
10495960
34.
35.

Haemoglobin synthesis in erythropoietin-stimulated J2E cells does not require increased numbers of transferrin receptors.

Callus BA, Busfield SJ, Rossi E, Tilbrook PA, Chappell D, Morgan EH, Klinken SP.

Eur J Biochem. 1997 Dec 1;250(2):459-66.

37.
38.

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells.

Tilbrook PA, Ingley E, Williams JH, Hibbs ML, Klinken SP.

EMBO J. 1997 Apr 1;16(7):1610-9.

39.

Prevention of apoptosis in J2E erythroid cells by erythropoietin: involvement of JAK2 but not MAP kinases.

Chappell D, Tilbrook PA, Bittorf T, Colley SM, Meyer GT, Klinken SP.

Cell Death Differ. 1997 Feb;4(2):105-13.

40.

Method for measuring a comprehensive energy budget in a proliferating cell system over multiple cell cycles.

Guppy M, Kong SE, Niu X, Busfield S, Klinken SP.

J Cell Physiol. 1997 Jan;170(1):1-7.

PMID:
9012779
41.

Inhibition of proliferation but not erythroid differentiation of J2E cells by rapamycin.

Jaster R, Bittorf T, Klinken SP, Brock J.

Biochem Pharmacol. 1996 May 3;51(9):1181-5.

PMID:
8645341
42.

Regulation of the erythropoietin receptor and involvement of JAK2 in differentiation of J2E erythroid cells.

Tilbrook PA, Bittorf T, Callus BA, Busfield SJ, Ingley E, Klinken SP.

Cell Growth Differ. 1996 Apr;7(4):511-20.

43.

Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin.

Tilbrook PA, Bittorf T, Busfield SJ, Chappell D, Klinken SP.

J Biol Chem. 1996 Feb 16;271(7):3453-9.

44.

Truncated erythropoietin receptor in a murine erythroleukemia cell line.

Bittorf T, Busfield SJ, Klinken SP, Tilbrook PA.

Int J Biochem Cell Biol. 1996 Feb;28(2):175-81.

PMID:
8729004
45.

Interferon-alpha inhibits erythropoietin-induced proliferation, but not differentiation, and restricts erythroleukemia development.

Lai CM, Swaminathan N, Beilharz MW, Papadimitriou J, Klinken SP.

J Interferon Cytokine Res. 1995 Aug;15(8):669-75.

PMID:
8528938
46.

Amiloride suppresses erythropoietin-induced proliferation and MAP kinase, but potentiates differentiation of J2E cells.

Callus B, Tilbrook PA, Busfield SJ, Cull VS, Bittorf T, Klinken SP.

Exp Cell Res. 1995 Jul;219(1):39-46.

PMID:
7543055
47.

The major erythroid DNA-binding protein GATA-1 is stimulated by erythropoietin but not by chemical inducers of erythroid differentiation.

Busfield SJ, Spadaccini A, Riches KJ, Tilbrook PA, Klinken SP.

Eur J Biochem. 1995 Jun 1;230(2):475-80.

48.

A rapid fatal erythroleukemia caused by J2E cells can be treated ex vivo with erythropoietin.

Farr TJ, Lai CM, Beilharz MW, Papadimitriou J, Riches K, Rossi E, Garcia-Webb P, Klinken SP.

Leukemia. 1995 May;9(5):900-7.

PMID:
7769854
49.

Emergence of myeloid cells from cultures of J2E erythroid cells is linked with karyotypic abnormalities.

Keil U, Busfield SJ, Farr TJ, Papadimitriou J, Green AR, Begley CG, Klinken SP.

Cell Growth Differ. 1995 Apr;6(4):439-48.

50.

Erythropoietin exerts transcriptional and translational control over globin synthesis in J2E cells.

Busfield SJ, Chappell DS, Jennings G, Trengove NJ, Riches KJ, Callus BA, Tilbrook PA, Klinken SP.

Cell Growth Differ. 1995 Apr;6(4):429-37.

Supplemental Content

Loading ...
Support Center