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Items: 1 to 50 of 140

1.

Erratum: Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting: Erratum.

Klingler M, Decristoforo C, Rangger C, Summer D, Foster J, Sosabowski JK, von Guggenberg E.

Theranostics. 2019 Jun 19;9(16):4595-4596. doi: 10.7150/thno.36746. eCollection 2019.

2.

Correction: Klingler, M., et al. Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m. Pharmaceuticals 2019, 12, 13.

Klingler M, Rangger C, Summer D, Kaeopookum P, Decristoforo C, von Guggenberg E.

Pharmaceuticals (Basel). 2019 Jun 13;12(2). pii: E88. doi: 10.3390/ph12020088.

3.

The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning.

Ray S, Rosenberg MI, Chanut-Delalande H, Decaras A, Schwertner B, Toubiana W, Auman T, Schnellhammer I, Teuscher M, Valenti P, Khila A, Klingler M, Payre F.

Elife. 2019 Mar 21;8. pii: e39748. doi: 10.7554/eLife.39748.

4.

Prolonged monitoring of postprandial lipid metabolism after a western meal rich in linoleic acid (LA) and carbohydrates.

Shokry E, Raab R, Kirchberg FF, Hellmuth C, Klingler M, Demmelmair H, Koletzko B, Uhl O.

Appl Physiol Nutr Metab. 2019 Mar 20. doi: 10.1139/apnm-2018-0798. [Epub ahead of print]

PMID:
30893569
5.

Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m.

Klingler M, Rangger C, Summer D, Kaeopookum P, Decristoforo C, von Guggenberg E.

Pharmaceuticals (Basel). 2019 Jan 15;12(1). pii: E13. doi: 10.3390/ph12010013. Erratum in: Pharmaceuticals (Basel). 2019 Jun 13;12(2):.

6.

A re-inducible gap gene cascade patterns the anterior-posterior axis of insects in a threshold-free fashion.

Boos A, Distler J, Rudolf H, Klingler M, El-Sherif E.

Elife. 2018 Dec 20;7. pii: e41208. doi: 10.7554/eLife.41208.

7.

DOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use.

Klingler M, Summer D, Rangger C, Haubner R, Foster J, Sosabowski J, Decristoforo C, Virgolini I, von Guggenberg E.

J Nucl Med. 2019 Jul;60(7):1010-1016. doi: 10.2967/jnumed.118.221283. Epub 2018 Dec 7.

PMID:
30530828
8.

Assessment of volume preservation performed before or after partial nephrectomy accurately predicts postoperative renal function: Results from a prospective multicenter study.

Klingler MJ, Babitz SK, Kutikov A, Campi R, Hatzichristodoulou G, Sanguedolce F, Brookman-May S, Akdogan B, Capitanio U, Roscigno M, Volpe A, Marszalek M, Uzzo RG, Antonelli A, Langenhuijsen J, Carini M, Minervini A, Lane BR.

Urol Oncol. 2019 Jan;37(1):33-39. doi: 10.1016/j.urolonc.2018.11.007. Epub 2018 Nov 23.

PMID:
30473205
9.

Multimerization results in formation of re-bindable metabolites: A proof of concept study with FSC-based minigastrin imaging probes targeting CCK2R expression.

Summer D, Kroess A, Woerndle R, Rangger C, Klingler M, Haas H, Kremser L, Lindner HH, von Guggenberg E, Decristoforo C.

PLoS One. 2018 Jul 30;13(7):e0201224. doi: 10.1371/journal.pone.0201224. eCollection 2018.

10.

Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting.

Klingler M, Decristoforo C, Rangger C, Summer D, Foster J, Sosabowski JK, von Guggenberg E.

Theranostics. 2018 Apr 16;8(11):2896-2908. doi: 10.7150/thno.24378. eCollection 2018. Erratum in: Theranostics. 2019 Jun 19;9(16):4595-4596.

11.

Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression.

Summer D, Rangger C, Klingler M, Laverman P, Franssen GM, Lechner BE, Orasch T, Haas H, von Guggenberg E, Decristoforo C.

Contrast Media Mol Imaging. 2018 Apr 10;2018:3171794. doi: 10.1155/2018/3171794. eCollection 2018.

12.

Double abdomen in a short-germ insect: Zygotic control of axis formation revealed in the beetle Tribolium castaneum.

Ansari S, Troelenberg N, Dao VA, Richter T, Bucher G, Klingler M.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1819-1824. doi: 10.1073/pnas.1716512115. Epub 2018 Feb 5.

13.

The flipflop orphan genes are required for limb bud eversion in the Tribolium embryo.

Thümecke S, Beermann A, Klingler M, Schröder R.

Front Zool. 2017 Oct 19;14:48. doi: 10.1186/s12983-017-0234-9. eCollection 2017.

14.

Speed regulation of genetic cascades allows for evolvability in the body plan specification of insects.

Zhu X, Rudolf H, Healey L, François P, Brown SJ, Klingler M, El-Sherif E.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8646-E8655. doi: 10.1073/pnas.1702478114. Epub 2017 Sep 25.

15.

177Lu Labeled Cyclic Minigastrin Analogues with Therapeutic Activity in CCK2R Expressing Tumors: Preclinical Evaluation of a Kit Formulation.

Rangger C, Klingler M, Balogh L, Pöstényi Z, Polyak A, Pawlak D, Mikołajczak R, von Guggenberg E.

Mol Pharm. 2017 Sep 5;14(9):3045-3058. doi: 10.1021/acs.molpharmaceut.7b00241. Epub 2017 Aug 7.

16.

Whole blood glycerophospholipids in dried blood spots - a reliable marker for the fatty acid status.

Drzymała-Czyż S, Janich S, Klingler M, Demmelmair J, Walkowiak J, Koletzko B.

Chem Phys Lipids. 2017 Oct;207(Pt A):1-9. doi: 10.1016/j.chemphyslip.2017.06.003. Epub 2017 Jun 29.

PMID:
28669639
17.

Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding.

Summer D, Grossrubatscher L, Petrik M, Michalcikova T, Novy Z, Rangger C, Klingler M, Haas H, Kaeopookum P, von Guggenberg E, Haubner R, Decristoforo C.

Bioconjug Chem. 2017 Jun 21;28(6):1722-1733. doi: 10.1021/acs.bioconjchem.7b00182. Epub 2017 May 10.

18.

Hippocampal GluA2 and GluA4 protein but not corresponding mRNA and promoter methylation levels are modulated at retrieval in spatial learning of the rat.

Rössner B, Klingler M, Bulat T, Sase A, Zeilinger A, Spitzwieser M, Aradska J, Cichna-Markl M, Lubec G.

Amino Acids. 2017 Jan;49(1):117-127. doi: 10.1007/s00726-016-2335-8. Epub 2016 Oct 6.

PMID:
27714514
19.

Dalfampridine Effects Beyond Walking Speed in Multiple Sclerosis.

Fjeldstad C, Suárez G, Klingler M, Henney HR 3rd, Rabinowicz AL, Pardo G.

Int J MS Care. 2015 Nov-Dec;17(6):275-83. doi: 10.7224/1537-2073.2014-036.

20.

Effects of Dalfampridine Extended-release Tablets on 6-minute Walk Distance in Patients With Multiple Sclerosis: A Post Hoc Analysis of a Double-blind, Placebo-controlled Trial.

Applebee A, Goodman AD, Mayadev AS, Bethoux F, Goldman MD, Klingler M, Blight AR, Carrazana EJ.

Clin Ther. 2015 Dec 1;37(12):2780-7. doi: 10.1016/j.clinthera.2015.10.014. Epub 2015 Nov 10.

21.

The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology.

Schmitt-Engel C, Schultheis D, Schwirz J, Ströhlein N, Troelenberg N, Majumdar U, Dao VA, Grossmann D, Richter T, Tech M, Dönitz J, Gerischer L, Theis M, Schild I, Trauner J, Koniszewski ND, Küster E, Kittelmann S, Hu Y, Lehmann S, Siemanowski J, Ulrich J, Panfilio KA, Schröder R, Morgenstern B, Stanke M, Buchhholz F, Frasch M, Roth S, Wimmer EA, Schoppmeier M, Klingler M, Bucher G.

Nat Commun. 2015 Jul 28;6:7822. doi: 10.1038/ncomms8822.

22.

Evaluation of Dalfampridine Extended Release 5 and 10 mg in Multiple Sclerosis: A Randomized Controlled Trial.

Yapundich R, Applebee A, Bethoux F, Goldman MD, Hutton GJ, Mass M, Pardo G, Klingler M, Henney HR 3rd, Blight AR, Carrazana EJ.

Int J MS Care. 2015 May-Jun;17(3):138-45. doi: 10.7224/1537-2073.2014-040.

23.

Metastasizing Esthesioneuroblastoma in a Dog.

Siudak K, Klingler M, Schmidt MJ, Herden C.

Vet Pathol. 2015 Jul;52(4):692-5. doi: 10.1177/0300985814559402. Epub 2014 Nov 26.

PMID:
25428407
24.

iBeetle-Base: a database for RNAi phenotypes in the red flour beetle Tribolium castaneum.

Dönitz J, Schmitt-Engel C, Grossmann D, Gerischer L, Tech M, Schoppmeier M, Klingler M, Bucher G.

Nucleic Acids Res. 2015 Jan;43(Database issue):D720-5. doi: 10.1093/nar/gku1054. Epub 2014 Nov 5.

25.

A pooled analysis of two phase 3 clinical trials of dalfampridine in patients with multiple sclerosis.

Goodman AD, Brown TR, Schapiro RT, Klingler M, Cohen R, Blight AR.

Int J MS Care. 2014 Fall;16(3):153-60. doi: 10.7224/1537-2073.2013-023.

26.

Comparison of the endocranial- and brain volumes in brachycephalic dogs, mesaticephalic dogs and Cavalier King Charles spaniels in relation to their body weight.

Schmidt MJ, Amort KH, Failing K, Klingler M, Kramer M, Ondreka N.

Acta Vet Scand. 2014 May 13;56:30. doi: 10.1186/1751-0147-56-30.

27.

Predictors for the development of temporomandibular disorders in scuba divers.

Lobbezoo F, van Wijk AJ, Klingler MC, Ruiz Vicente E, van Dijk CJ, Eijkman MA.

J Oral Rehabil. 2014 Aug;41(8):573-80. doi: 10.1111/joor.12178. Epub 2014 Apr 28.

PMID:
24766672
28.

Changes of molecular glycerophospholipid species in plasma and red blood cells during docosahexaenoic acid supplementation.

Uhl O, Demmelmair H, Klingler M, Koletzko B.

Lipids. 2013 Nov;48(11):1103-13. doi: 10.1007/s11745-013-3837-8. Epub 2013 Sep 17.

PMID:
24043586
29.

Comparison of closure times for cranial base synchondroses in mesaticephalic, brachycephalic, and Cavalier King Charles Spaniel dogs.

Schmidt MJ, Volk H, Klingler M, Failing K, Kramer M, Ondreka N.

Vet Radiol Ultrasound. 2013 Sep-Oct;54(5):497-503. doi: 10.1111/vru.12072. Epub 2013 Jun 19.

PMID:
23782353
30.

Tc-knirps plays different roles in the specification of antennal and mandibular parasegment boundaries and is regulated by a pair-rule gene in the beetle Tribolium castaneum.

Peel AD, Schanda J, Grossmann D, Ruge F, Oberhofer G, Gilles AF, Schinko JB, Klingler M, Bucher G.

BMC Dev Biol. 2013 Jun 18;13:25. doi: 10.1186/1471-213X-13-25.

31.

Evidence for rhombomeric organization of multiple respiratory oscillators in the bullfrog brainstem.

Klingler MJ, Hedrick MS.

Respir Physiol Neurobiol. 2013 Mar 1;186(1):7-15. doi: 10.1016/j.resp.2012.12.007. Epub 2012 Dec 29.

PMID:
23279869
32.

Comparison of the incorporation of orally administered DHA into plasma, erythrocyte and cheek cell glycerophospholipids.

Klingler M, Klem S, Demmelmair H, Koletzko B.

Br J Nutr. 2013 Mar 14;109(5):962-8. doi: 10.1017/S000711451200222X. Epub 2012 Jul 3.

PMID:
22874641
33.

Genetic variations in polyunsaturated fatty acid metabolism--implications for child health?

Lattka E, Klopp N, Demmelmair H, Klingler M, Heinrich J, Koletzko B.

Ann Nutr Metab. 2012;60 Suppl 3:8-17. doi: 10.1159/000337308. Epub 2012 May 15. Review.

34.

Novel methodologies for assessing omega-3 fatty acid status - a systematic review.

Klingler M, Koletzko B.

Br J Nutr. 2012 Jun;107 Suppl 2:S53-63. doi: 10.1017/S0007114512001468. Review.

PMID:
22591903
35.

Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition.

Klem S, Klingler M, Demmelmair H, Koletzko B.

PLoS One. 2012;7(3):e33874. doi: 10.1371/journal.pone.0033874. Epub 2012 Mar 30.

36.

Fatty acid status determination by cheek cell sampling combined with methanol-based ultrasound extraction of glycerophospholipids.

Klingler M, Demmelmair H, Koletzko B, Glaser C.

Lipids. 2011 Oct;46(10):981-90. doi: 10.1007/s11745-011-3576-7. Epub 2011 Jun 17.

PMID:
21681560
37.

Functionality of the GAL4/UAS system in Tribolium requires the use of endogenous core promoters.

Schinko JB, Weber M, Viktorinova I, Kiupakis A, Averof M, Klingler M, Wimmer EA, Bucher G.

BMC Dev Biol. 2010 May 19;10:53. doi: 10.1186/1471-213X-10-53.

38.

Apparent role of Tribolium orthodenticle in anteroposterior blastoderm patterning largely reflects novel functions in dorsoventral axis formation and cell survival.

Kotkamp K, Klingler M, Schoppmeier M.

Development. 2010 Jun;137(11):1853-62. doi: 10.1242/dev.047043. Epub 2010 Apr 28.

39.

Red flour beetle (Tribolium) germline transformation and insertional mutagenesis.

Berghammer AJ, Weber M, Trauner J, Klingler M.

Cold Spring Harb Protoc. 2009 Aug;2009(8):pdb.prot5259. doi: 10.1101/pdb.prot5259. No abstract available.

PMID:
20147235
40.

The red flour beetle, Tribolium castaneum (Coleoptera): a model for studies of development and pest biology.

Brown SJ, Shippy TD, Miller S, Bolognesi R, Beeman RW, Lorenzen MD, Bucher G, Wimmer EA, Klingler M.

Cold Spring Harb Protoc. 2009 Aug;2009(8):pdb.emo126. doi: 10.1101/pdb.emo126. No abstract available.

PMID:
20147228
41.

Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps.

Trauner J, Schinko J, Lorenzen MD, Shippy TD, Wimmer EA, Beeman RW, Klingler M, Bucher G, Brown SJ.

BMC Biol. 2009 Nov 5;7:73. doi: 10.1186/1741-7007-7-73.

42.

An ancient anterior patterning system promotes caudal repression and head formation in ecdysozoa.

Schoppmeier M, Fischer S, Schmitt-Engel C, Löhr U, Klingler M.

Curr Biol. 2009 Nov 17;19(21):1811-5. doi: 10.1016/j.cub.2009.09.026. Epub 2009 Oct 8.

43.

Probing the Drosophila retinal determination gene network in Tribolium (II): The Pax6 genes eyeless and twin of eyeless.

Yang X, Weber M, Zarinkamar N, Posnien N, Friedrich F, Wigand B, Beutel R, Damen WG, Bucher G, Klingler M, Friedrich M.

Dev Biol. 2009 Sep 1;333(1):215-27. doi: 10.1016/j.ydbio.2009.06.013. Epub 2009 Jun 13.

44.

The Tribolium ortholog of knirps and knirps-related is crucial for head segmentation but plays a minor role during abdominal patterning.

Cerny AC, Grossmann D, Bucher G, Klingler M.

Dev Biol. 2008 Sep 1;321(1):284-94. doi: 10.1016/j.ydbio.2008.05.527. Epub 2008 May 20.

45.

The genome of the model beetle and pest Tribolium castaneum.

Tribolium Genome Sequencing Consortium, Richards S, Gibbs RA, Weinstock GM, Brown SJ, Denell R, Beeman RW, Gibbs R, Beeman RW, Brown SJ, Bucher G, Friedrich M, Grimmelikhuijzen CJ, Klingler M, Lorenzen M, Richards S, Roth S, Schröder R, Tautz D, Zdobnov EM, Muzny D, Gibbs RA, Weinstock GM, Attaway T, Bell S, Buhay CJ, Chandrabose MN, Chavez D, Clerk-Blankenburg KP, Cree A, Dao M, Davis C, Chacko J, Dinh H, Dugan-Rocha S, Fowler G, Garner TT, Garnes J, Gnirke A, Hawes A, Hernandez J, Hines S, Holder M, Hume J, Jhangiani SN, Joshi V, Khan ZM, Jackson L, Kovar C, Kowis A, Lee S, Lewis LR, Margolis J, Morgan M, Nazareth LV, Nguyen N, Okwuonu G, Parker D, Richards S, Ruiz SJ, Santibanez J, Savard J, Scherer SE, Schneider B, Sodergren E, Tautz D, Vattahil S, Villasana D, White CS, Wright R, Park Y, Beeman RW, Lord J, Oppert B, Lorenzen M, Brown S, Wang L, Savard J, Tautz D, Richards S, Weinstock G, Gibbs RA, Liu Y, Worley K, Weinstock G, Elsik CG, Reese JT, Elhaik E, Landan G, Graur D, Arensburger P, Atkinson P, Beeman RW, Beidler J, Brown SJ, Demuth JP, Drury DW, Du YZ, Fujiwara H, Lorenzen M, Maselli V, Osanai M, Park Y, Robertson HM, Tu Z, Wang JJ, Wang S, Richards S, Song H, Zhang L, Sodergren E, Werner D, Stanke M, Morgenstern B, Solovyev V, Kosarev P, Brown G, Chen HC, Ermolaeva O, Hlavina W, Kapustin Y, Kiryutin B, Kitts P, Maglott D, Pruitt K, Sapojnikov V, Souvorov A, Mackey AJ, Waterhouse RM, Wyder S, Zdobnov EM, Zdobnov EM, Wyder S, Kriventseva EV, Kadowaki T, Bork P, Aranda M, Bao R, Beermann A, Berns N, Bolognesi R, Bonneton F, Bopp D, Brown SJ, Bucher G, Butts T, Chaumot A, Denell RE, Ferrier DE, Friedrich M, Gordon CM, Jindra M, Klingler M, Lan Q, Lattorff HM, Laudet V, von Levetsow C, Liu Z, Lutz R, Lynch JA, da Fonseca RN, Posnien N, Reuter R, Roth S, Savard J, Schinko JB, Schmitt C, Schoppmeier M, Schröder R, Shippy TD, Simonnet F, Marques-Souza H, Tautz D, Tomoyasu Y, Trauner J, Van der Zee M, Vervoort M, Wittkopp N, Wimmer EA, Yang X, Jones AK, Sattelle DB, Ebert PR, Nelson D, Scott JG, Beeman RW, Muthukrishnan S, Kramer KJ, Arakane Y, Beeman RW, Zhu Q, Hogenkamp D, Dixit R, Oppert B, Jiang H, Zou Z, Marshall J, Elpidina E, Vinokurov K, Oppert C, Zou Z, Evans J, Lu Z, Zhao P, Sumathipala N, Altincicek B, Vilcinskas A, Williams M, Hultmark D, Hetru C, Jiang H, Grimmelikhuijzen CJ, Hauser F, Cazzamali G, Williamson M, Park Y, Li B, Tanaka Y, Predel R, Neupert S, Schachtner J, Verleyen P, Raible F, Bork P, Friedrich M, Walden KK, Robertson HM, Angeli S, Forêt S, Bucher G, Schuetz S, Maleszka R, Wimmer EA, Beeman RW, Lorenzen M, Tomoyasu Y, Miller SC, Grossmann D, Bucher G.

Nature. 2008 Apr 24;452(7190):949-55. doi: 10.1038/nature06784. Epub 2008 Mar 23.

PMID:
18362917
46.

Antenna and all gnathal appendages are similarly transformed by homothorax knock-down in the cricket Gryllus bimaculatus.

Ronco M, Uda T, Mito T, Minelli A, Noji S, Klingler M.

Dev Biol. 2008 Jan 1;313(1):80-92. Epub 2007 Oct 10.

47.

Docosahexaenoic acid supply in pregnancy affects placental expression of fatty acid transport proteins.

Larqué E, Krauss-Etschmann S, Campoy C, Hartl D, Linde J, Klingler M, Demmelmair H, Caño A, Gil A, Bondy B, Koletzko B.

Am J Clin Nutr. 2006 Oct;84(4):853-61.

PMID:
17023713
48.

The effect of docosahexaenoic acid and folic acid supplementation on placental apoptosis and proliferation.

Klingler M, Blaschitz A, Campoy C, Caño A, Molloy AM, Scott JM, Dohr G, Demmelmair H, Koletzko B, Desoye G.

Br J Nutr. 2006 Jul;96(1):182-90.

PMID:
16870008
49.

Maintenance of segment and appendage primordia by the Tribolium gene knödel.

Wohlfrom H, Schinko JB, Klingler M, Bucher G.

Mech Dev. 2006 Jun;123(6):430-9. Epub 2006 May 5.

50.

Expression pattern of fatty acid transport protein-1 (FATP-1), FATP-4 and heart-fatty acid binding protein (H-FABP) genes in human term placenta.

Larqué E, Demmelmair H, Klingler M, De Jonge S, Bondy B, Koletzko B.

Early Hum Dev. 2006 Oct;82(10):697-701. Epub 2006 Mar 30.

PMID:
16574350

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