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Items: 30


Long-term effect of CFTR modulator therapy on airway nitric oxide.

Grasemann H, Klingel M, Avolio J, Prentice C, Gonska T, Tullis E, Ratjen F.

Eur Respir J. 2019 Oct 10. pii: 1901113. doi: 10.1183/13993003.01113-2019. [Epub ahead of print] No abstract available.


Effect of changes in tidal volume on multiple breath washout outcomes.

Ratjen F, Jensen R, Klingel M, McDonald R, Moore C, Benseler N, Wilson D, Stanojevic S.

PLoS One. 2019 Jul 3;14(7):e0219309. doi: 10.1371/journal.pone.0219309. eCollection 2019.


Oral Azithromycin and Response to Pulmonary Exacerbations Treated with Intravenous Tobramycin in Children with Cystic Fibrosis.

Klingel M, Stanojevic S, Tullis E, Ratjen F, Waters V.

Ann Am Thorac Soc. 2019 Jul;16(7):861-867. doi: 10.1513/AnnalsATS.201811-774OC.


The impact of delayed critical care outreach team activation on in-hospital mortality and other patient outcomes: a historical cohort study.

Tillmann BW, Klingel ML, McLeod SL, Anderson S, Haddara W, Parry NG.

Can J Anaesth. 2018 Nov;65(11):1210-1217. doi: 10.1007/s12630-018-1180-5. Epub 2018 Jul 6.


Epidemiology of Clonal Pseudomonas aeruginosa Infection in a Canadian Cystic Fibrosis Population.

Middleton MA, Layeghifard M, Klingel M, Stanojevic S, Yau YCW, Zlosnik JEA, Coriati A, Ratjen FA, Tullis ED, Stephenson A, Wilcox P, Freitag A, Chilvers M, McKinney M, Lavoie A, Wang PW, Guttman DS, Waters VJ.

Ann Am Thorac Soc. 2018 Jul;15(7):827-836. doi: 10.1513/AnnalsATS.201801-007OC.


The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF.

Eckford PDW, McCormack J, Munsie L, He G, Stanojevic S, Pereira SL, Ho K, Avolio J, Bartlett C, Yang JY, Wong AP, Wellhauser L, Huan LJ, Jiang JX, Ouyang H, Du K, Klingel M, Kyriakopoulou L, Gonska T, Moraes TJ, Strug LJ, Rossant J, Ratjen F, Bear CE.

J Cyst Fibros. 2019 Jan;18(1):35-43. doi: 10.1016/j.jcf.2018.03.013. Epub 2018 Oct 10.


Changes in Lung Clearance Index in Preschool-aged Patients with Cystic Fibrosis Treated with Ivacaftor (GOAL): A Clinical Trial.

Ratjen F, Klingel M, Black P, Powers MR, Grasemann H, Solomon M, Sagel SD, Donaldson SH, Rowe SM, Rosenfeld M.

Am J Respir Crit Care Med. 2018 Aug 15;198(4):526-528. doi: 10.1164/rccm.201802-0243LE. No abstract available.


Early detection using qPCR of Pseudomonas aeruginosa infection in children with cystic fibrosis undergoing eradication treatment.

Blanchard AC, Rooney AM, Yau Y, Zhang Y, Stapleton PJ, Horton E, Klingel M, Stanojevic S, Ratjen F, Coburn B, Waters V.

J Cyst Fibros. 2018 Nov;17(6):723-728. doi: 10.1016/j.jcf.2018.02.008. Epub 2018 Mar 7.


Echocardiography Grading for Pulmonary Arteriovenous Malformation Screening in Children with Hereditary Hemorrhagic Telangiectasia.

Fernandopulle N, Mertens L, Klingel M, Manson D, Ratjen F.

J Pediatr. 2018 Apr;195:288-291.e1. doi: 10.1016/j.jpeds.2017.11.047. Epub 2017 Dec 20.


Changes in magnetic resonance imaging scores and ventilation inhomogeneity in children with cystic fibrosis pulmonary exacerbations.

Grasemann H, Ciet P, Amin R, McDonald N, Klingel M, Tiddens HAWM, Ratjen F, Grosse-Wortmann L.

Eur Respir J. 2017 Aug 24;50(2). pii: 1700244. doi: 10.1183/13993003.00244-2017. Print 2017 Aug. No abstract available.


Presentation and outcomes of necrotizing soft tissue infections.

Chen KJ, Klingel M, McLeod S, Mindra S, Ng VK.

Int J Gen Med. 2017 Jul 31;10:215-220. doi: 10.2147/IJGM.S131768. eCollection 2017.


Extracorporeal membrane oxygenation (ECMO) as a treatment strategy for severe acute respiratory distress syndrome (ARDS) in the low tidal volume era: A systematic review.

Tillmann BW, Klingel ML, Iansavichene AE, Ball IM, Nagpal AD.

J Crit Care. 2017 Oct;41:64-71. doi: 10.1016/j.jcrc.2017.04.041. Epub 2017 Apr 27. Review.


Pilot trial of tobramycin inhalation powder in cystic fibrosis patients with chronic Burkholderia cepacia complex infection.

Waters V, Yau Y, Beaudoin T, Wettlaufer J, Tom SK, McDonald N, Rizvi L, Klingel M, Ratjen F, Tullis E.

J Cyst Fibros. 2017 Jul;16(4):492-495. doi: 10.1016/j.jcf.2017.02.008. Epub 2017 Mar 3.


Effect of Hydroxyurea Therapy on Pulmonary Function in Children with Sickle Cell Anemia.

McLaren A, Klingel M, Behera S, Odame I, Kirby-Allen M, Grasemann H.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):689-691. doi: 10.1164/rccm.201606-1119LE. No abstract available.


Longitudinal study of Stenotrophomonas maltophilia antibody levels and outcomes in cystic fibrosis patients.

Wettlaufer J, Klingel M, Yau Y, Stanojevic S, Tullis E, Ratjen F, Waters V.

J Cyst Fibros. 2017 Jan;16(1):58-63. doi: 10.1016/j.jcf.2016.06.007. Epub 2016 Jun 23.


A Systematic Approach to Multiple Breath Nitrogen Washout Test Quality.

Jensen R, Stanojevic S, Klingel M, Pizarro ME, Hall GL, Ramsey K, Foong R, Saunders C, Robinson PD, Webster H, Hardaker K, Kane M, Ratjen F.

PLoS One. 2016 Jun 15;11(6):e0157523. doi: 10.1371/journal.pone.0157523. eCollection 2016.


Reducing length of stay and satisfying learner needs.

Shepherd L, Chahine S, Klingel M, Zibrowski E, Meiwald A, Lingard L.

Perspect Med Educ. 2016 Jun;5(3):170-8. doi: 10.1007/s40037-016-0276-2.


An Assessment of the Industry-Faculty Surgeon Relationship Within Colon and Rectum Surgical Training Programs.

Patel SV, Klingel M, Sonoda T.

J Surg Educ. 2016 Jul-Aug;73(4):595-9. doi: 10.1016/j.jsurg.2016.01.013. Epub 2016 Mar 7.


Lung clearance index response in patients with CF with class III CFTR mutations.

Kane M, Gonska T, Jensen R, Avolio J, Klingel M, Stanojevic S, Ratjen F.

Thorax. 2016 May;71(5):476-7. doi: 10.1136/thoraxjnl-2015-207894. Epub 2016 Mar 4. No abstract available.


First Responder Accuracy Using SALT during Mass-casualty Incident Simulation.

Lee CW, McLeod SL, Van Aarsen K, Klingel M, Franc JM, Peddle MB.

Prehosp Disaster Med. 2016 Apr;31(2):150-4. doi: 10.1017/S1049023X16000091. Epub 2016 Feb 9.


Changes in airway inflammation during pulmonary exacerbations in patients with cystic fibrosis and primary ciliary dyskinesia.

Ratjen F, Waters V, Klingel M, McDonald N, Dell S, Leahy TR, Yau Y, Grasemann H.

Eur Respir J. 2016 Mar;47(3):829-36. doi: 10.1183/13993003.01390-2015. Epub 2015 Nov 19.


Predictors of posttraumatic stress and preferred sources of social support among Canadian paramedics.

Donnelly EA, Bradford P, Davis M, Hedges C, Klingel M.

CJEM. 2016 May;18(3):205-12. doi: 10.1017/cem.2015.92. Epub 2015 Sep 1.


Prolongation of antibiotic treatment for cystic fibrosis pulmonary exacerbations.

Waters V, Stanojevic S, Klingel M, Chiang J, Sonneveld N, Kukkar R, Tullis E, Ratjen F.

J Cyst Fibros. 2015 Nov;14(6):770-6. doi: 10.1016/j.jcf.2015.07.010. Epub 2015 Aug 9.


Effect of ivacaftor therapy on exhaled nitric oxide in patients with cystic fibrosis.

Grasemann H, Gonska T, Avolio J, Klingel M, Tullis E, Ratjen F.

J Cyst Fibros. 2015 Nov;14(6):727-32. doi: 10.1016/j.jcf.2015.07.001. Epub 2015 Jul 11.


Funding source and primary outcome changes in clinical trials registered on are associated with the reporting of a statistically significant primary outcome: a cross-sectional study.

Ramagopalan SV, Skingsley AP, Handunnetthi L, Magnus D, Klingel M, Pakpoor J, Goldacre B.

Version 2. F1000Res. 2015 Mar 26 [revised 2015 Jan 1];4:80. doi: 10.12688/f1000research.6312.2. eCollection 2015.


Factors associated with response to treatment of pulmonary exacerbations in cystic fibrosis patients.

Waters VJ, Stanojevic S, Sonneveld N, Klingel M, Grasemann H, Yau YC, Tullis E, Wilcox P, Freitag A, Chilvers M, Ratjen FA.

J Cyst Fibros. 2015 Nov;14(6):755-62. doi: 10.1016/j.jcf.2015.01.007. Epub 2015 Feb 14.


Prevalence of primary outcome changes in clinical trials registered on a cross-sectional study.

Ramagopalan S, Skingsley AP, Handunnetthi L, Klingel M, Magnus D, Pakpoor J, Goldacre B.

F1000Res. 2014 Mar 26;3:77. doi: 10.12688/f1000research.3784.1. eCollection 2014.


Risks associated with red blood cell transfusion in the trauma population, a meta-analysis.

Patel SV, Kidane B, Klingel M, Parry N.

Injury. 2014 Oct;45(10):1522-33. doi: 10.1016/j.injury.2014.05.015. Epub 2014 May 24. Review.


A meta-analysis of the effect of inspired oxygen concentration on the incidence of surgical site infection following cesarean section.

Klingel ML, Patel SV.

Int J Obstet Anesth. 2013 Apr;22(2):104-12. doi: 10.1016/j.ijoa.2013.01.001. Epub 2013 Mar 13. Review.


Comparative evaluation of AMPLICOR HPV PCR and Linear Array assays on SurePath liquid-based Pap samples for the detection of high-risk HPV genotypes.

Chernesky M, Jang D, Portillo E, Smieja M, Chong S, Buracond S, Klingel M, El Sebai R, Kapala J, Patel J, Biers K, Harroun N, Doucette C, Sumner J.

J Clin Virol. 2011 Mar;50(3):201-4. doi: 10.1016/j.jcv.2010.12.003. Epub 2010 Dec 30.


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