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Items: 6


Specific tools for targeting and expression in Müller glial cells.

Pellissier LP, Hoek RM, Vos RM, Aartsen WM, Klimczak RR, Hoyng SA, Flannery JG, Wijnholds J.

Mol Ther Methods Clin Dev. 2014 Mar 19;1:14009. doi: 10.1038/mtm.2014.9. eCollection 2014.


In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous.

Dalkara D, Byrne LC, Klimczak RR, Visel M, Yin L, Merigan WH, Flannery JG, Schaffer DV.

Sci Transl Med. 2013 Jun 12;5(189):189ra76. doi: 10.1126/scitranslmed.3005708.


AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa.

Dalkara D, Kolstad KD, Guerin KI, Hoffmann NV, Visel M, Klimczak RR, Schaffer DV, Flannery JG.

Mol Ther. 2011 Sep;19(9):1602-8. doi: 10.1038/mt.2011.62. Epub 2011 Apr 26.


A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells.

Klimczak RR, Koerber JT, Dalkara D, Flannery JG, Schaffer DV.

PLoS One. 2009 Oct 14;4(10):e7467. doi: 10.1371/journal.pone.0007467.


Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.

Dalkara D, Kolstad KD, Caporale N, Visel M, Klimczak RR, Schaffer DV, Flannery JG.

Mol Ther. 2009 Dec;17(12):2096-102. doi: 10.1038/mt.2009.181. Epub 2009 Aug 11.


Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.

Samuelson AV, Klimczak RR, Thompson DB, Carr CE, Ruvkun G.

Cold Spring Harb Symp Quant Biol. 2007;72:489-97. doi: 10.1101/sqb.2007.72.068.


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