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Items: 35


PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.

Andrzejewski S, Klimcakova E, Johnson RM, Tabariès S, Annis MG, McGuirk S, Northey JJ, Chénard V, Sriram U, Papadopoli DJ, Siegel PM, St-Pierre J.

Cell Metab. 2017 Nov 7;26(5):778-787.e5. doi: 10.1016/j.cmet.2017.09.006. Epub 2017 Oct 5.


Soluble CD163 is associated with CD163 mRNA expression in adipose tissue and with insulin sensitivity in steady-state condition but not in response to calorie restriction.

Kračmerová J, Rossmeislová L, Kováčová Z, Klimčáková E, Polák J, Tencerová M, Mališová L, Štich V, Langin D, Šiklová M.

J Clin Endocrinol Metab. 2014 Mar;99(3):E528-35. doi: 10.1210/jc.2013-3348. Epub 2014 Jan 13.


WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.

Hammarstedt A, Hedjazifar S, Jenndahl L, Gogg S, Grünberg J, Gustafson B, Klimcakova E, Stich V, Langin D, Laakso M, Smith U.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2563-8. doi: 10.1073/pnas.1211255110. Epub 2013 Jan 28.


Adipose tissue secretion and expression of adipocyte-produced and stromavascular fraction-produced adipokines vary during multiple phases of weight-reducing dietary intervention in obese women.

Siklova-Vitkova M, Klimcakova E, Polak J, Kovacova Z, Tencerova M, Rossmeislova L, Bajzova M, Langin D, Stich V.

J Clin Endocrinol Metab. 2012 Jul;97(7):E1176-81. doi: 10.1210/jc.2011-2380. Epub 2012 Apr 24.


PGC-1α promotes the growth of ErbB2/Neu-induced mammary tumors by regulating nutrient supply.

Klimcakova E, Chénard V, McGuirk S, Germain D, Avizonis D, Muller WJ, St-Pierre J.

Cancer Res. 2012 Mar 15;72(6):1538-46. doi: 10.1158/0008-5472.CAN-11-2967. Epub 2012 Jan 19.


Catecholamine and insulin control of lipolysis in subcutaneous adipose tissue during long-term diet-induced weight loss in obese women.

Koppo K, Siklová-Vitková M, Klimcáková E, Polák J, Marques MA, Berlan M, Van de Voorde J, Bulow J, Langin D, de Glisezinski I, Stich V.

Am J Physiol Endocrinol Metab. 2012 Jan 15;302(2):E226-32. doi: 10.1152/ajpendo.00240.2011. Epub 2011 Nov 8.


Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain.

Austin S, Klimcakova E, St-Pierre J.

Free Radic Biol Med. 2011 Dec 15;51(12):2243-8. doi: 10.1016/j.freeradbiomed.2011.08.036. Epub 2011 Sep 10.


Macrophage gene expression is related to obesity and the metabolic syndrome in human subcutaneous fat as well as in visceral fat.

Klimcakova E, Roussel B, Kovacova Z, Kovacikova M, Siklova-Vitkova M, Combes M, Hejnova J, Decaunes P, Maoret JJ, Vedral T, Viguerie N, Bourlier V, Bouloumié A, Stich V, Langin D.

Diabetologia. 2011 Apr;54(4):876-87. doi: 10.1007/s00125-010-2014-3. Epub 2011 Jan 26.


Worsening of obesity and metabolic status yields similar molecular adaptations in human subcutaneous and visceral adipose tissue: decreased metabolism and increased immune response.

Klimcáková E, Roussel B, Márquez-Quiñones A, Kovácová Z, Kováciková M, Combes M, Siklová-Vítková M, Hejnová J, Srámková P, Bouloumié A, Viguerie N, Stich V, Langin D.

J Clin Endocrinol Metab. 2011 Jan;96(1):E73-82. doi: 10.1210/jc.2010-1575. Epub 2010 Nov 3.


Dietary intervention-induced weight loss decreases macrophage content in adipose tissue of obese women.

Kováčiková M, Sengenes C, Kováčová Z, Šiklová-Vítková M, Klimčáková E, Polák J, Rossmeislová L, Bajzová M, Hejnová J, Hněvkovská Z, Bouloumié A, Langin D, Štich V.

Int J Obes (Lond). 2011 Jan;35(1):91-8. doi: 10.1038/ijo.2010.112. Epub 2010 Jun 8.


Adipokines and dietary interventions in human obesity.

Klimcakova E, Kovacikova M, Stich V, Langin D.

Obes Rev. 2010 Jun;11(6):446-56. doi: 10.1111/j.1467-789X.2009.00704.x. Epub 2010 Jan 6. Review.


TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet.

Grau K, Cauchi S, Holst C, Astrup A, Martinez JA, Saris WH, Blaak EE, Oppert JM, Arner P, Rössner S, Macdonald IA, Klimcakova E, Langin D, Pedersen O, Froguel P, Sørensen TI.

Am J Clin Nutr. 2010 Feb;91(2):472-9. doi: 10.3945/ajcn.2009.27947. Epub 2009 Dec 23.


Effect of hyperinsulinemia and very-low-calorie diet on interstitial cytokine levels in subcutaneous adipose tissue of obese women.

Siklova-Vitkova M, Polak J, Klimcakova E, Vrzalova J, Hejnova J, Kovacikova M, Kovacova Z, Bajzova M, Rossmeislova L, Hnevkovska Z, Langin D, Stich V.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1154-61. doi: 10.1152/ajpendo.00086.2009. Epub 2009 Sep 1.


Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization.

Capel F, Klimcáková E, Viguerie N, Roussel B, Vítková M, Kováciková M, Polák J, Kovácová Z, Galitzky J, Maoret JJ, Hanácek J, Pers TH, Bouloumié A, Stich V, Langin D.

Diabetes. 2009 Jul;58(7):1558-67. doi: 10.2337/db09-0033. Epub 2009 Apr 28.


Secretion of adiponectin multimeric complexes from adipose tissue explants is not modified by very low calorie diet.

Kovacova Z, Vitkova M, Kovacikova M, Klimcakova E, Bajzova M, Hnevkovska Z, Rossmeislova L, Stich V, Langin D, Polak J.

Eur J Endocrinol. 2009 Apr;160(4):585-92. doi: 10.1530/EJE-08-0727. Epub 2009 Jan 20.


Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women.

Capel F, Viguerie N, Vega N, Dejean S, Arner P, Klimcakova E, Martinez JA, Saris WH, Holst C, Taylor M, Oppert JM, Sørensen TI, Clément K, Vidal H, Langin D.

J Clin Endocrinol Metab. 2008 Nov;93(11):4315-22. doi: 10.1210/jc.2008-0814. Epub 2008 Sep 9.


[Relation between insulin resistance and amount of visceral adipose tissue].

Bajzová M, Kováciková M, Vítková M, Polák J, Klimcáková E, Srp A, Vedral T, Mikulásek L, Srámková SP, Stich V, Hejnová J.

Cas Lek Cesk. 2008;147(7):376-80. Czech.


Visfatin expression in subcutaneous adipose tissue of pre-menopausal women: relation to hormones and weight reduction.

Kovacikova M, Vitkova M, Klimcakova E, Polak J, Hejnova J, Bajzova M, Kovacova Z, Viguerie N, Langin D, Stich V.

Eur J Clin Invest. 2008 Jul;38(7):516-22. doi: 10.1111/j.1365-2362.2008.01964.x.


Exercise-induced lipid mobilization in subcutaneous adipose tissue is mainly related to natriuretic peptides in overweight men.

Moro C, Pillard F, de Glisezinski I, Klimcakova E, Crampes F, Thalamas C, Harant I, Marques MA, Lafontan M, Berlan M.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E505-13. doi: 10.1152/ajpendo.90227.2008. Epub 2008 Jun 17.


Retinol-binding protein 4 expression in visceral and subcutaneous fat in human obesity.

Bajzová M, Kováciková M, Vítková M, Klimcáková E, Polák J, Kovácová Z, Viguerie N, Vedral T, Mikulásek L, Srámková P, Srp A, Hejnová J, Langin D, Stich V.

Physiol Res. 2008;57(6):927-34. Epub 2007 Nov 30.


Phosphodiesterase-5A and neutral endopeptidase activities in human adipocytes do not control atrial natriuretic peptide-mediated lipolysis.

Moro C, Klimcakova E, Lafontan M, Berlan M, Galitzky J.

Br J Pharmacol. 2007 Dec;152(7):1102-10. Epub 2007 Oct 1.


The transcriptional coactivator peroxisome proliferator activated receptor (PPAR)gamma coactivator-1 alpha and the nuclear receptor PPAR alpha control the expression of glycerol kinase and metabolism genes independently of PPAR gamma activation in human white adipocytes.

Mazzucotelli A, Viguerie N, Tiraby C, Annicotte JS, Mairal A, Klimcakova E, Lepin E, Delmar P, Dejean S, Tavernier G, Lefort C, Hidalgo J, Pineau T, Fajas L, Clément K, Langin D.

Diabetes. 2007 Oct;56(10):2467-75. Epub 2007 Jul 23.


Profiling of adipokines secreted from human subcutaneous adipose tissue in response to PPAR agonists.

Klimcakova E, Moro C, Mazzucotelli A, Lolmède K, Viguerie N, Galitzky J, Stich V, Langin D.

Biochem Biophys Res Commun. 2007 Jul 6;358(3):897-902. Epub 2007 May 11.


Plasma levels and adipose tissue messenger ribonucleic acid expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-induced changes in insulin sensitivity.

Vitkova M, Klimcakova E, Kovacikova M, Valle C, Moro C, Polak J, Hanacek J, Capel F, Viguerie N, Richterova B, Bajzova M, Hejnova J, Stich V, Langin D.

J Clin Endocrinol Metab. 2007 Jun;92(6):2330-5. Epub 2007 Apr 3.


The atrial natriuretic peptide- and catecholamine-induced lipolysis and expression of related genes in adipose tissue in hypothyroid and hyperthyroid patients.

Polak J, Moro C, Klimcakova E, Kovacikova M, Bajzova M, Vitkova M, Kovacova Z, Sotornik R, Berlan M, Viguerie N, Langin D, Stich V.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E246-51. Epub 2007 Mar 27.


Atrial natriuretic peptide inhibits the production of adipokines and cytokines linked to inflammation and insulin resistance in human subcutaneous adipose tissue.

Moro C, Klimcakova E, Lolmède K, Berlan M, Lafontan M, Stich V, Bouloumié A, Galitzky J, Arner P, Langin D.

Diabetologia. 2007 May;50(5):1038-47. Epub 2007 Feb 23.


An increase in plasma adiponectin multimeric complexes follows hypocaloric diet-induced weight loss in obese and overweight pre-menopausal women.

Polak J, Kovacova Z, Jacek M, Klimcakova E, Kovacikova M, Vitkova M, Kuda O, Sebela M, Samcova E, Stich V.

Clin Sci (Lond). 2007 Jun;112(11):557-65.


Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor alpha in obese women.

Polak J, Klimcakova E, Moro C, Viguerie N, Berlan M, Hejnova J, Richterova B, Kraus I, Langin D, Stich V.

Metabolism. 2006 Oct;55(10):1375-81.


Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men.

Klimcakova E, Polak J, Moro C, Hejnova J, Majercik M, Viguerie N, Berlan M, Langin D, Stich V.

J Clin Endocrinol Metab. 2006 Dec;91(12):5107-12. Epub 2006 Sep 12.


[Changes in serum and adipose tissue fatty acid composition after low calorie diet with respect to dietary fat content in obese].

Vecka M, Richterová B, Zák A, Tvrzická E, Srámková P, Stanková B, Klimcáková E, Stich V.

Cas Lek Cesk. 2006;145(6):464-9. Czech.


Atrial natriuretic peptide stimulates lipid mobilization during repeated bouts of endurance exercise.

Moro C, Polak J, Hejnova J, Klimcakova E, Crampes F, Stich V, Lafontan M, Berlan M.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E864-9. Epub 2005 Nov 15.


Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects.

Polak J, Moro C, Klimcakova E, Hejnova J, Majercik M, Viguerie N, Langin D, Lafontan M, Stich V, Berlan M.

Diabetologia. 2005 Dec;48(12):2631-40. Epub 2005 Nov 5.


Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets.

Viguerie N, Vidal H, Arner P, Holst C, Verdich C, Avizou S, Astrup A, Saris WH, Macdonald IA, Klimcakova E, Clément K, Martinez A, Hoffstedt J, Sørensen TI, Langin D; Nutrient-Gene Interactions in Human Obesity--Implications for Dietary Guideline (NUGENOB) project.

Diabetologia. 2005 Jan;48(1):123-31. Epub 2004 Dec 29.


Effect of endurance training on adrenergic control of lipolysis in adipose tissue of obese women.

Richterova B, Stich V, Moro C, Polak J, Klimcakova E, Majercik M, Harant I, Viguerie N, Crampes F, Langin D, Lafontan M, Berlan M.

J Clin Endocrinol Metab. 2004 Mar;89(3):1325-31.


Adiponectin gene expression and plasma values in obese women during very-low-calorie diet. Relationship with cardiovascular risk factors and insulin resistance.

Garaulet M, Viguerie N, Porubsky S, Klimcakova E, Clement K, Langin D, Stich V.

J Clin Endocrinol Metab. 2004 Feb;89(2):756-60.


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