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Items: 31


Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function.

Scott J, Thakar S, Mao Y, Qin H, Hejran H, Lee SY, Yu T, Klezovitch O, Cheng H, Mu Y, Ghosh S, Vasioukhin V, Zou Y.

iScience. 2019 Oct 25;20:25-41. doi: 10.1016/j.isci.2019.09.005. Epub 2019 Sep 9.


Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells.

Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien WH, Fernandez TE, Cooper JA, Vasioukhin V.

Dev Cell. 2017 Jun 5;41(5):481-495.e5. doi: 10.1016/j.devcel.2017.05.002. Epub 2017 May 25.


Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.

Beattie R, Postiglione MP, Burnett LE, Laukoter S, Streicher C, Pauler FM, Xiao G, Klezovitch O, Vasioukhin V, Ghashghaei TH, Hippenmeyer S.

Neuron. 2017 May 3;94(3):517-533.e3. doi: 10.1016/j.neuron.2017.04.012.


DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.

Kwan J, Sczaniecka A, Heidary Arash E, Nguyen L, Chen CC, Ratkovic S, Klezovitch O, Attisano L, McNeill H, Emili A, Vasioukhin V.

Genes Dev. 2016 Dec 15;30(24):2696-2709. doi: 10.1101/gad.284539.116.


Cadherin signaling: keeping cells in touch.

Klezovitch O, Vasioukhin V.

F1000Res. 2015 Aug 12;4(F1000 Faculty Rev):550. doi: 10.12688/f1000research.6445.1. eCollection 2015. Review.


ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

Nguyen LT, Tretiakova MS, Silvis MR, Lucas J, Klezovitch O, Coleman I, Bolouri H, Kutyavin VI, Morrissey C, True LD, Nelson PS, Vasioukhin V.

Cancer Cell. 2015 Jun 8;27(6):797-808. doi: 10.1016/j.ccell.2015.05.005.


Your gut is right to turn left.

Klezovitch O, Vasioukhin V.

Dev Cell. 2013 Sep 30;26(6):553-4. doi: 10.1016/j.devcel.2013.08.018.


Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.

Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V.

Dev Biol. 2013 May 15;377(2):375-84. doi: 10.1016/j.ydbio.2013.02.019. Epub 2013 Mar 4.


Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis.

Clark BS, Cui S, Miesfeld JB, Klezovitch O, Vasioukhin V, Link BA.

Development. 2012 May;139(9):1599-610. doi: 10.1242/dev.078097.


α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1.

Silvis MR, Kreger BT, Lien WH, Klezovitch O, Rudakova GM, Camargo FD, Lantz DM, Seykora JT, Vasioukhin V.

Sci Signal. 2011 May 24;4(174):ra33. doi: 10.1126/scisignal.2001823.


Discs large 5 is required for polarization of citron kinase in mitotic neural precursors.

Chang Y, Klezovitch O, Walikonis RS, Vasioukhin V, LoTurco JJ.

Cell Cycle. 2010 May 15;9(10):1990-7. Epub 2010 May 15.


alphaE-catenin is not a significant regulator of beta-catenin signaling in the developing mammalian brain.

Lien WH, Klezovitch O, Null M, Vasioukhin V.

J Cell Sci. 2008 May 1;121(Pt 9):1357-62. doi: 10.1242/jcs.020537. Epub 2008 Apr 8.


A causal role for ERG in neoplastic transformation of prostate epithelium.

Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, Nelson PS, Vasioukhin V.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2105-10. doi: 10.1073/pnas.0711711105. Epub 2008 Feb 1.


Cadherin-catenin proteins in vertebrate development.

Lien WH, Klezovitch O, Vasioukhin V.

Curr Opin Cell Biol. 2006 Oct;18(5):499-506. Epub 2006 Jul 21. Review.


alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.

Lien WH, Klezovitch O, Fernandez TE, Delrow J, Vasioukhin V.

Science. 2006 Mar 17;311(5767):1609-12.


Hepsin promotes prostate cancer progression and metastasis.

Klezovitch O, Chevillet J, Mirosevich J, Roberts RL, Matusik RJ, Vasioukhin V.

Cancer Cell. 2004 Aug;6(2):185-95.


Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.

Klezovitch O, Fernandez TE, Tapscott SJ, Vasioukhin V.

Genes Dev. 2004 Mar 1;18(5):559-71.


Structural determinants in the C-terminal domain of apolipoprotein E mediating binding to the protein core of human aortic biglycan.

Klezovitch O, Formato M, Cherchi GM, Weisgraber KH, Scanu AM.

J Biol Chem. 2000 Jun 23;275(25):18913-8.


Effect of phospholipase A2 digestion on the conformation and lysine/fibrinogen binding properties of human lipoprotein[a].

Fless GM, Kirk EW, Klezovitch O, Santiago JY, Edelstein C, Hoover-Plow J, Scanu AM.

J Lipid Res. 1999 Apr;40(4):583-92.


Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.

Mochalkin I, Cheng B, Klezovitch O, Scanu AM, Tulinsky A.

Biochemistry. 1999 Feb 16;38(7):1990-8.


Lipoprotein(a): identification of subjects with a superbinding capacity for fibrinogen.

Scanu AM, Atzeni MM, Edelstein C, Tonolo G, Maioli M, Klezovitch O.

Clin Genet. 1997 Nov;52(5):367-70.


Functional and metabolic differences between elastase-generated fragments of human lipoprotein[a] and apolipoprotein[a].

Edelstein C, Italia JA, Klezovitch O, Scanu AM.

J Lipid Res. 1996 Aug;37(8):1786-801.


Heterogeneity of lipoprotein (a): growing complexities.

Klezovitch O, Scanu AM.

Curr Opin Lipidol. 1995 Aug;6(4):223-8. Review.


Characterization of reactions catalysed by yeast phosphatidylinositol synthase.

Klezovitch O, Brandenburger Y, Geindre M, Deshusses J.

FEBS Lett. 1993 Apr 12;320(3):256-60.

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