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Items: 1 to 50 of 52

1.

The NO-heme signaling hypothesis.

Kleschyov AL.

Free Radic Biol Med. 2017 Nov;112:544-552. doi: 10.1016/j.freeradbiomed.2017.08.025. Epub 2017 Sep 3.

PMID:
28877508
2.
3.

Electron paramagnetic resonance in a biomedical laboratory.

Kleschyov AL, Terekhov M.

Bioanalysis. 2013 Sep;5(18):2233-7. doi: 10.4155/bio.13.200. No abstract available.

PMID:
24053238
4.

Heparin-polynitroxide derivatives: a platform for new diagnostic and therapeutic agents in cardiovascular disease?

Kleschyov AL, Sen' VD.

Future Med Chem. 2013 Mar;5(4):385-8. doi: 10.4155/fmc.13.18. No abstract available.

PMID:
23495686
5.

Heparin-polynitroxides: synthesis and preliminary evaluation as cardiovascular EPR/MR imaging probes and extracellular space-targeted antioxidants.

Kleschyov AL, Sen' V, Golubev V, Münnemann K, Hinderberger D, Lackner KJ, Weber S, Terekhov M, Schreiber LM, Münzel T.

Eur J Med Chem. 2012 Dec;58:265-71. doi: 10.1016/j.ejmech.2012.09.028. Epub 2012 Oct 5.

PMID:
23127990
6.

Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress.

Kröller-Schön S, Schulz E, Wenzel P, Kleschyov AL, Hortmann M, Torzewski M, Oelze M, Renné T, Daiber A, Münzel T.

Basic Res Cardiol. 2011 Nov;106(6):1147-58. doi: 10.1007/s00395-011-0227-3. Epub 2011 Oct 2.

PMID:
21964558
7.

α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation.

Schuhmacher S, Foretz M, Knorr M, Jansen T, Hortmann M, Wenzel P, Oelze M, Kleschyov AL, Daiber A, Keaney JF Jr, Wegener G, Lackner K, Münzel T, Viollet B, Schulz E.

Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):560-6. doi: 10.1161/ATVBAHA.110.219543. Epub 2011 Jan 4.

8.

Spin-labeled heparins as polarizing agents for dynamic nuclear polarization.

Dollmann BC, Kleschyov AL, Sen V, Golubev V, Schreiber LM, Spiess HW, Münnemann K, Hinderberger D.

Chemphyschem. 2010 Dec 3;11(17):3656-63. doi: 10.1002/cphc.201000559.

PMID:
20960494
9.

Inactivation of soluble guanylate cyclase by stoichiometric S-nitrosation.

Mayer B, Kleschyov AL, Stessel H, Russwurm M, Münzel T, Koesling D, Schmidt K.

Mol Pharmacol. 2009 Apr;75(4):886-91. doi: 10.1124/mol.108.052142. Epub 2008 Dec 29.

10.

Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases.

Li H, Hortmann M, Daiber A, Oelze M, Ostad MA, Schwarz PM, Xu H, Xia N, Kleschyov AL, Mang C, Warnholtz A, Münzel T, Förstermann U.

J Pharmacol Exp Ther. 2008 Sep;326(3):745-53. doi: 10.1124/jpet.108.139030. Epub 2008 Jun 11.

11.

Sirolimus-induced vascular dysfunction. Increased mitochondrial and nicotinamide adenosine dinucleotide phosphate oxidase-dependent superoxide production and decreased vascular nitric oxide formation.

Jabs A, Göbel S, Wenzel P, Kleschyov AL, Hortmann M, Oelze M, Daiber A, Münzel T.

J Am Coll Cardiol. 2008 Jun 3;51(22):2130-8. doi: 10.1016/j.jacc.2008.01.058.

12.

Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH.

Deng S, Kruger A, Kleschyov AL, Kalinowski L, Daiber A, Wojnowski L.

Free Radic Biol Med. 2007 Feb 15;42(4):466-73. Epub 2006 Nov 15.

PMID:
17275678
13.

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):850-7. Epub 2007 Jan 25.

14.

Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice.

Wenzel P, Hink U, Oelze M, Seeling A, Isse T, Bruns K, Steinhoff L, Brandt M, Kleschyov AL, Schulz E, Lange K, Weiner H, Lehmann J, Lackner KJ, Kawamoto T, Münzel T, Daiber A.

Br J Pharmacol. 2007 Feb;150(4):526-33. Epub 2007 Jan 15.

15.

Electron paramagnetic resonance (EPR) spin trapping of biological nitric oxide.

Kleschyov AL, Wenzel P, Munzel T.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 15;851(1-2):12-20. Epub 2006 Oct 27. Review.

PMID:
17070113
16.

Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.

Oelze M, Daiber A, Brandes RP, Hortmann M, Wenzel P, Hink U, Schulz E, Mollnau H, von Sandersleben A, Kleschyov AL, Mülsch A, Li H, Förstermann U, Münzel T.

Hypertension. 2006 Oct;48(4):677-84. Epub 2006 Aug 28.

17.

NADPH oxidase accounts for enhanced superoxide production and impaired endothelium-dependent smooth muscle relaxation in BKbeta1-/- mice.

Oelze M, Warnholtz A, Faulhaber J, Wenzel P, Kleschyov AL, Coldewey M, Hink U, Pongs O, Fleming I, Wassmann S, Meinertz T, Ehmke H, Daiber A, Münzel T.

Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1753-9. Epub 2006 Jun 8.

18.

Dinitrosyl-iron triggers apoptosis in Jurkat cells despite overexpression of Bcl-2.

Kleschyov AL, Strand S, Schmitt S, Gottfried D, Skatchkov M, Sjakste N, Daiber A, Umansky V, Munzel T.

Free Radic Biol Med. 2006 Apr 15;40(8):1340-8. Epub 2005 Dec 27.

PMID:
16631524
19.

Mechanisms underlying dysfunction of carotid arteries in genetically hyperlipidemic rabbits.

August M, Wingerter O, Oelze M, Wenzel P, Kleschyov AL, Daiber A, Mülsch A, Münzel T, Tsilimingas N.

Nitric Oxide. 2006 Nov;15(3):241-51. Epub 2006 Apr 4.

PMID:
16597505
20.

Mechanisms of increased vascular superoxide production in an experimental model of idiopathic dilated cardiomyopathy.

Mollnau H, Oelze M, August M, Wendt M, Daiber A, Schulz E, Baldus S, Kleschyov AL, Materne A, Wenzel P, Hink U, Nickenig G, Fleming I, Münzel T.

Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2554-9. Epub 2005 Oct 13.

21.

Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.

Wendt MC, Daiber A, Kleschyov AL, Mülsch A, Sydow K, Schulz E, Chen K, Keaney JF Jr, Lassègue B, Walter U, Griendling KK, Münzel T.

Free Radic Biol Med. 2005 Aug 1;39(3):381-91. Epub 2005 Apr 7.

PMID:
15993337
22.

Molecular mechanisms underlying the role of nitric oxide in the cardiovascular system.

Stoclet JC, Troncy E, Muller B, Brua C, Kleschyov AL.

Expert Opin Investig Drugs. 1998 Nov;7(11):1769-79.

PMID:
15991928
23.

Role of the adventitia in the cyclic GMP-mediated relaxant effect of N-hydroxy-L-arginine in rat aorta.

Beranova P, Schott C, Chalupsky K, Kleschyov AL, Stoclet JC, Muller B.

J Vasc Res. 2005 Jul-Aug;42(4):331-6. Epub 2005 Jun 20.

PMID:
15976507
24.

Nomega-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents.

Beranova P, Chalupsky K, Kleschyov AL, Schott C, Boucher JL, Mansuy D, Munzel T, Muller B, Stoclet JC.

Eur J Pharmacol. 2005 Jun 15;516(3):260-7.

PMID:
15964563
25.

Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates.

Daiber A, Oelze M, Coldewey M, Bachschmid M, Wenzel P, Sydow K, Wendt M, Kleschyov AL, Stalleicken D, Ullrich V, Mülsch A, Münzel T.

Mol Pharmacol. 2004 Dec;66(6):1372-82. Epub 2004 Aug 26.

26.

Endothelium- and nitric oxide-dependent vasorelaxing activities of gamma-butyrobetaine esters: possible link to the antiischemic activities of mildronate.

Sjakste N, Kleschyov AL, Boucher JL, Baumane L, Dzintare M, Meirena D, Sjakste J, Sydow K, Münzel T, Kalvinsh I.

Eur J Pharmacol. 2004 Jul 8;495(1):67-73.

PMID:
15219822
27.

Detection of superoxide and peroxynitrite in model systems and mitochondria by the luminol analogue L-012.

Daiber A, Oelze M, August M, Wendt M, Sydow K, Wieboldt H, Kleschyov AL, Munzel T.

Free Radic Res. 2004 Mar;38(3):259-69.

PMID:
15129734
28.

Measurement of NAD(P)H oxidase-derived superoxide with the luminol analogue L-012.

Daiber A, August M, Baldus S, Wendt M, Oelze M, Sydow K, Kleschyov AL, Munzel T.

Free Radic Biol Med. 2004 Jan 1;36(1):101-11.

PMID:
14732294
29.

Does nitric oxide mediate the vasodilator activity of nitroglycerin?

Kleschyov AL, Oelze M, Daiber A, Huang Y, Mollnau H, Schulz E, Sydow K, Fichtlscherer B, Mülsch A, Münzel T.

Circ Res. 2003 Oct 31;93(9):e104-12. Epub 2003 Oct 9.

30.

Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells.

Mollnau H, Schulz E, Daiber A, Baldus S, Oelze M, August M, Wendt M, Walter U, Geiger C, Agrawal R, Kleschyov AL, Meinertz T, Münzel T.

Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):615-21. Epub 2003 Mar 6.

31.

Advanced spin trapping of vascular nitric oxide using colloid iron diethyldithiocarbamate.

Kleschyov AL, Münzel T.

Methods Enzymol. 2002;359:42-51. No abstract available.

PMID:
12481558
32.

Detection of superoxide in vascular tissue.

Münzel T, Afanas'ev IB, Kleschyov AL, Harrison DG.

Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1761-8. Review.

33.

Heme oxygenase-1-mediated protection: potential role of nonheme iron-nitric oxide complexes.

Kleschyov AL, Wendt M, Munzel T.

Circulation. 2002 Jun 25;105(25):e196; author reply e196. No abstract available.

34.

Nitric oxide transport and storage in the cardiovascular system.

Muller B, Kleschyov AL, Alencar JL, Vanin A, Stoclet JC.

Ann N Y Acad Sci. 2002 May;962:131-9. Review.

PMID:
12076970
35.

Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.

Mollnau H, Wendt M, Szöcs K, Lassègue B, Schulz E, Oelze M, Li H, Bodenschatz M, August M, Kleschyov AL, Tsilimingas N, Walter U, Förstermann U, Meinertz T, Griendling K, Münzel T.

Circ Res. 2002 Mar 8;90(4):E58-65.

36.

Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery.

Kleschyov AL, Hubert G, Munzel T, Stoclet JC, Bucher B.

BMC Pharmacol. 2002;2:3. Epub 2002 Feb 8.

37.

Novel activation of non-selective cationic channels by dinitrosyl iron-thiosulfate in PC12 cells.

Giannone G, Takeda K, Kleschyov AL.

J Physiol. 2000 Dec 15;529 Pt 3:735-45. Erratum in: J Physiol 2001 Feb;530(3):575. Kleyschov AL [corrected to Kleschyov AL].

38.

Adventitia-derived nitric oxide in rat aortas exposed to endotoxin: cell origin and functional consequences.

Kleschyov AL, Muller B, Keravis T, Stoeckel ME, Stoclet JC.

Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2743-51.

39.

Spin trapping of vascular nitric oxide using colloid Fe(II)-diethyldithiocarbamate.

Kleschyov AL, Mollnau H, Oelze M, Meinertz T, Huang Y, Harrison DG, Munzel T.

Biochem Biophys Res Commun. 2000 Aug 28;275(2):672-7.

PMID:
10964721
40.

Inducible NO synthase activity in blood vessels and heart: new insight into cell origin and consequences.

Muller B, Kleschyov AL, Gyorgy K, Stoclet JC.

Physiol Res. 2000;49(1):19-26. Review.

41.

Triggering role of nitric oxide in the delayed protective effect of monophosphoryl lipid A in rat heart.

György K, Muller B, Vegh A, Kleschyov AL, Stoclet JC.

Br J Pharmacol. 1999 Aug;127(8):1892-8.

42.

The inducible nitric oxide synthase in vascular and cardiac tissue.

Stoclet JC, Muller B, György K, Andriantsiothaina R, Kleschyov AL.

Eur J Pharmacol. 1999 Jun 30;375(1-3):139-55. Review.

PMID:
10443572
43.
44.

Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock.

Stoclet JC, Martínez MC, Ohlmann P, Chasserot S, Schott C, Kleschyov AL, Schneider F, Andriantsitohaina R.

Circulation. 1999 Jul 13;100(2):107-12.

45.

Role of adventitial nitric oxide in vascular hyporeactivity induced by lipopolysaccharide in rat aorta.

Kleschyov AL, Muller B, Schott C, Stoclet JC.

Br J Pharmacol. 1998 Jun;124(4):623-6.

46.
48.

Nitric oxide production and endothelium-dependent vasorelaxation induced by wine polyphenols in rat aorta.

Andriambeloson E, Kleschyov AL, Muller B, Beretz A, Stoclet JC, Andriantsitohaina R.

Br J Pharmacol. 1997 Mar;120(6):1053-8.

49.

Nitric oxide generation from extracellularly applied NG-hydroxy-L-arginine in LPS-activated RAW 264 macrophages.

Vetrovsky P, Kleschyov AL, Entlicher G, Poindron P, Stoclet JC.

Biochim Biophys Acta. 1997 Feb 11;1334(1):51-6.

PMID:
9042365
50.

Induction of NO production by polyosides from the wall of Streptococcus mutans OMZ175 in the rat aorta.

Martin V, Kleschyov AL, Schöller M, Klein JP, Beretz A.

Adv Exp Med Biol. 1997;418:669-72. No abstract available.

PMID:
9331740

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