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Items: 1 to 50 of 399

1.

Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.

Lu X, Xiao H, Li S, Pang X, Song J, Liu S, Cheng H, Li Y, Wang X, Huang C, Guo T, Ter Meulen J, Daffis S, Yan J, Dai L, Rao Z, Klenk HD, Qi J, Shi Y, Gao GF.

Cell Rep. 2019 Jan 8;26(2):438-446.e5. doi: 10.1016/j.celrep.2018.12.065.

2.

Receptor-binding properties of influenza viruses isolated from gulls.

Gambaryan AS, Matrosovich TY, Boravleva EY, Lomakina NF, Yamnikova SS, Tuzikov AB, Pazynina GV, Bovin NV, Fouchier RAM, Klenk HD, Matrosovich MN.

Virology. 2018 Sep;522:37-45. doi: 10.1016/j.virol.2018.07.004. Epub 2018 Jul 12.

PMID:
30014856
3.

Immunization of Domestic Ducks with Live Nonpathogenic H5N3 Influenza Virus Prevents Shedding and Transmission of Highly Pathogenic H5N1 Virus to Chickens.

Gambaryan A, Gordeychuk I, Boravleva E, Lomakina N, Kropotkina E, Lunitsin A, Klenk HD, Matrosovich M.

Viruses. 2018 Mar 31;10(4). pii: E164. doi: 10.3390/v10040164.

4.

Acetylcholine Receptor Antibody Titers and Clinical Course after Influenza Vaccination in Patients with Myasthenia Gravis: A Double-Blind Randomized Controlled Trial (ProPATIent-Trial).

Tackenberg B, Schneider M, Blaes F, Eienbröker C, Schade-Brittinger C, Wellek A, Deschauer M, Eickmann M, Klenk HD, Müller HH, Sommer N.

EBioMedicine. 2018 Feb;28:143-150. doi: 10.1016/j.ebiom.2018.01.007. Epub 2018 Jan 10.

5.

Marburg- and Ebolaviruses: A Look Back and Lessons for the Future.

Klenk HD, Slenczka W.

Methods Mol Biol. 2017;1628:3-14. doi: 10.1007/978-1-4939-7116-9_1.

PMID:
28573607
6.

pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs.

Gerlach T, Hensen L, Matrosovich T, Bergmann J, Winkler M, Peteranderl C, Klenk HD, Weber F, Herold S, Pöhlmann S, Matrosovich M.

J Virol. 2017 May 12;91(11). pii: e00246-17. doi: 10.1128/JVI.00246-17. Print 2017 Jun 1.

7.

H7N9 Influenza A Virus Exhibits Importin-α7-Mediated Replication in the Mammalian Respiratory Tract.

Bertram S, Thiele S, Dreier C, Resa-Infante P, Preuß A, van Riel D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD, Gabriel G.

Am J Pathol. 2017 Apr;187(4):831-840. doi: 10.1016/j.ajpath.2016.12.017. Epub 2017 Feb 9.

PMID:
28189564
8.

Immunization with live nonpathogenic H5N3 duck influenza virus protects chickens against highly pathogenic H5N1 virus.

Gambaryan AS, Boravleva EY, Lomakina NF, Kropotkina EA, Gordeychuk IV, Chvala IA, Drygin VV, Klenk HD, Matrosovich MN.

Acta Virol. 2016;60(3):316-27.

PMID:
27640442
9.

Intravirion cohesion of matrix protein M1 with ribonucleocapsid is a prerequisite of influenza virus infectivity.

Zhirnov OP, Manykin AA, Rossman JS, Klenk HD.

Virology. 2016 May;492:187-96. doi: 10.1016/j.virol.2016.02.021. Epub 2016 Mar 21.

10.

H1N1 Swine Influenza Viruses Differ from Avian Precursors by a Higher pH Optimum of Membrane Fusion.

Baumann J, Kouassi NM, Foni E, Klenk HD, Matrosovich M.

J Virol. 2015 Nov 25;90(3):1569-77. doi: 10.1128/JVI.02332-15. Print 2016 Feb 1.

11.

PB2 subunit of avian influenza virus subtype H9N2: a pandemic risk factor.

Sediri H, Thiele S, Schwalm F, Gabriel G, Klenk HD.

J Gen Virol. 2016 Jan;97(1):39-48. doi: 10.1099/jgv.0.000333. Epub 2015 Nov 11.

PMID:
26560088
12.

Role of Substitutions in the Hemagglutinin in the Emergence of the 1968 Pandemic Influenza Virus.

Van Poucke S, Doedt J, Baumann J, Qiu Y, Matrosovich T, Klenk HD, Van Reeth K, Matrosovich M.

J Virol. 2015 Dec;89(23):12211-6. doi: 10.1128/JVI.01292-15. Epub 2015 Sep 16.

13.

VACCINES. Ebola virus vaccines--preparing for the unexpected.

Klenk HD, Becker S.

Science. 2015 Aug 14;349(6249):693-4. doi: 10.1126/science.aad0681. No abstract available.

PMID:
26273043
14.

Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity.

Dolnik O, Volchkova VA, Escudero-Perez B, Lawrence P, Klenk HD, Volchkov VE.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S322-8. doi: 10.1093/infdis/jiv268. Epub 2015 Jun 19.

PMID:
26092855
15.

Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells.

Sediri H, Schwalm F, Gabriel G, Klenk HD.

Eur J Cell Biol. 2015 Jul-Sep;94(7-9):368-74. doi: 10.1016/j.ejcb.2015.05.012. Epub 2015 Jun 2.

PMID:
26074198
16.

Lessons to be learned from the ebolavirus outbreak in West Africa.

Klenk HD.

Emerg Microbes Infect. 2014 Aug;3(8):e61. doi: 10.1038/emi.2014.68. Epub 2014 Aug 27. No abstract available.

17.

Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.

Lu Y, Hardes K, Dahms SO, Böttcher-Friebertshäuser E, Steinmetzer T, Than ME, Klenk HD, Garten W.

Antiviral Res. 2015 Aug;120:89-100. doi: 10.1016/j.antiviral.2015.05.006. Epub 2015 May 26.

PMID:
26022200
18.

SnapShot: Evolution of human influenza A viruses.

Wendel I, Matrosovich M, Klenk HD.

Cell Host Microbe. 2015 Mar 11;17(3):416-416.e1. doi: 10.1016/j.chom.2015.02.001.

19.

Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

Weber M, Sediri H, Felgenhauer U, Binzen I, Bänfer S, Jacob R, Brunotte L, García-Sastre A, Schmid-Burgk JL, Schmidt T, Hornung V, Kochs G, Schwemmle M, Klenk HD, Weber F.

Cell Host Microbe. 2015 Mar 11;17(3):309-319. doi: 10.1016/j.chom.2015.01.005. Epub 2015 Feb 19.

20.

The avian-origin PB1 gene segment facilitated replication and transmissibility of the H3N2/1968 pandemic influenza virus.

Wendel I, Rubbenstroth D, Doedt J, Kochs G, Wilhelm J, Staeheli P, Klenk HD, Matrosovich M.

J Virol. 2015 Apr;89(8):4170-9. doi: 10.1128/JVI.03194-14. Epub 2015 Jan 28.

21.

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names.

Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST.

Viruses. 2014 Sep 26;6(9):3663-82. doi: 10.3390/v6093663.

22.

The hemagglutinin: a determinant of pathogenicity.

Böttcher-Friebertshäuser E, Garten W, Matrosovich M, Klenk HD.

Curr Top Microbiol Immunol. 2014;385:3-34. doi: 10.1007/82_2014_384. Review.

PMID:
25031010
23.

Influenza viruses en route from birds to man.

Klenk HD.

Cell Host Microbe. 2014 Jun 11;15(6):653-4. doi: 10.1016/j.chom.2014.05.019.

24.

PB2 mutations D701N and S714R promote adaptation of an influenza H5N1 virus to a mammalian host.

Czudai-Matwich V, Otte A, Matrosovich M, Gabriel G, Klenk HD.

J Virol. 2014 Aug;88(16):8735-42. doi: 10.1128/JVI.00422-14. Epub 2014 Jun 4.

25.

TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice.

Tarnow C, Engels G, Arendt A, Schwalm F, Sediri H, Preuss A, Nelson PS, Garten W, Klenk HD, Gabriel G, Böttcher-Friebertshäuser E.

J Virol. 2014 May;88(9):4744-51. doi: 10.1128/JVI.03799-13. Epub 2014 Feb 12.

26.

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA.

Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST.

Arch Virol. 2014 May;159(5):1229-37. doi: 10.1007/s00705-013-1877-2. Epub 2013 Nov 5.

27.

Activation of influenza A viruses by host proteases from swine airway epithelium.

Peitsch C, Klenk HD, Garten W, Böttcher-Friebertshäuser E.

J Virol. 2014 Jan;88(1):282-91. doi: 10.1128/JVI.01635-13. Epub 2013 Oct 23.

28.

The synergies of microorganisms enlightened - convergent approaches to delineating coinfections.

Klenk HD, Ron E, Sansonetti P, Tønjum T.

Pathog Dis. 2013 Nov;69(2):71. doi: 10.1111/2049-632X.12101. No abstract available.

PMID:
24151184
29.

Influenza A virus proteins NS1 and hemagglutinin along with M2 are involved in stimulation of autophagy in infected cells.

Zhirnov OP, Klenk HD.

J Virol. 2013 Dec;87(24):13107-14. doi: 10.1128/JVI.02148-13. Epub 2013 Sep 11.

30.

Sialic Acid Receptors of Viruses.

Matrosovich M, Herrler G, Klenk HD.

Top Curr Chem. 2015;367:1-28. doi: 10.1007/128_2013_466. Review.

PMID:
23873408
31.

Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium.

Böttcher-Friebertshäuser E, Klenk HD, Garten W.

Pathog Dis. 2013 Nov;69(2):87-100. doi: 10.1111/2049-632X.12053. Epub 2013 Jul 2. Review.

PMID:
23821437
32.

Adaptive mutations in the H5N1 polymerase complex.

Gabriel G, Czudai-Matwich V, Klenk HD.

Virus Res. 2013 Dec 5;178(1):53-62. doi: 10.1016/j.virusres.2013.05.010. Epub 2013 Jun 1. Review.

PMID:
23732876
33.

Erratum: H7N9 avian influenza virus - search and re-search.

Wen YM, Klenk HD.

Emerg Microbes Infect. 2013 May;2(5):e26. doi: 10.1038/emi.2013.26.

34.

H7N9 avian influenza virus - search and re-search.

Wen YM, Klenk HD.

Emerg Microbes Infect. 2013 Apr;2(4):e18. doi: 10.1038/emi.2013.18. No abstract available. Erratum in: Emerg Microbes Infect. 2013 May;2(5):e26.

35.

Protease activation mutants elicit protective immunity against highly pathogenic avian influenza viruses of subtype H7 in chickens and mice.

Wagner R, Gabriel G, Schlesner M, Alex N, Herwig A, Werner O, Klenk HD.

Emerg Microbes Infect. 2013 Feb;2(2):e7. doi: 10.1038/emi2013.7. Epub 2013 Feb 27.

36.

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae.

Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Lofts LL, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST.

Arch Virol. 2013 Jun;158(6):1425-32. doi: 10.1007/s00705-012-1594-2. Epub 2013 Jan 29. No abstract available.

37.

Transmission studies resume for avian flu.

Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz JM, Kiselev OI, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Mettenleiter TC, Osterhaus AD, Palese P, Peiris JS, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG.

Science. 2013 Feb 1;339(6119):520-1. doi: 10.1126/science.1235140. Epub 2013 Jan 23. No abstract available.

38.

Influenza virus budding from the tips of cellular microvilli in differentiated human airway epithelial cells.

Kolesnikova L, Heck S, Matrosovich T, Klenk HD, Becker S, Matrosovich M.

J Gen Virol. 2013 May;94(Pt 5):971-6. doi: 10.1099/vir.0.049239-0. Epub 2013 Jan 3.

PMID:
23288421
39.

The microtubule motor protein KIF13A is involved in intracellular trafficking of the Lassa virus matrix protein Z.

Fehling SK, Noda T, Maisner A, Lamp B, Conzelmann KK, Kawaoka Y, Klenk HD, Garten W, Strecker T.

Cell Microbiol. 2013 Feb;15(2):315-34. doi: 10.1111/cmi.12095. Epub 2013 Jan 10.

PMID:
23279019
40.

[Evolution and infection biology of new influenza A viruses with pandemic potential].

Klenk HD.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Jan;56(1):15-21. doi: 10.1007/s00103-012-1584-2. Review. German.

PMID:
23275951
41.

Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.

Baron J, Tarnow C, Mayoli-Nüssle D, Schilling E, Meyer D, Hammami M, Schwalm F, Steinmetzer T, Guan Y, Garten W, Klenk HD, Böttcher-Friebertshäuser E.

J Virol. 2013 Feb;87(3):1811-20. doi: 10.1128/JVI.02320-12. Epub 2012 Nov 28.

42.

Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections.

Böttcher-Friebertshäuser E, Lu Y, Meyer D, Sielaff F, Steinmetzer T, Klenk HD, Garten W.

Vaccine. 2012 Dec 7;30(51):7374-80. doi: 10.1016/j.vaccine.2012.10.001. Epub 2012 Oct 13.

PMID:
23072892
43.

Characterization of the neuraminidase of the H1N1/09 pandemic influenza virus.

Gerlach T, Kühling L, Uhlendorff J, Laukemper V, Matrosovich T, Czudai-Matwich V, Schwalm F, Klenk HD, Matrosovich M.

Vaccine. 2012 Dec 7;30(51):7348-52. doi: 10.1016/j.vaccine.2012.09.078. Epub 2012 Oct 9.

PMID:
23063828
44.

Welcome from the Editors-in-Chief.

Wen YM, Klenk HD.

Emerg Microbes Infect. 2012 Jul;1(7):e1. doi: 10.1038/emi.2012.13. No abstract available.

45.

Receptor-binding profiles of H7 subtype influenza viruses in different host species.

Gambaryan AS, Matrosovich TY, Philipp J, Munster VJ, Fouchier RA, Cattoli G, Capua I, Krauss SL, Webster RG, Banks J, Bovin NV, Klenk HD, Matrosovich MN.

J Virol. 2012 Apr;86(8):4370-9. doi: 10.1128/JVI.06959-11. Epub 2012 Feb 15.

46.

Pause on avian flu transmission research.

Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz J, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Mettenleiter TC, Osterhaus AD, Palese P, Peiris JS, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG.

Science. 2012 Jan 27;335(6067):400-1. doi: 10.1126/science.335.6067.400. No abstract available.

47.

Influenza B virus with modified hemagglutinin cleavage site as a novel attenuated live vaccine.

Stech J, Garn H, Herwig A, Stech O, Dauber B, Wolff T, Mettenleiter TC, Klenk HD.

J Infect Dis. 2011 Nov 15;204(10):1483-90. doi: 10.1093/infdis/jir613. Epub 2011 Sep 14.

PMID:
21917878
48.

[NP gene of pandemic H1N1 virus attenuates virulence of mouse-adapted human influenza virus].

Zhirnov OP, Syrtsev VV, Schwalm F, Klenk HD.

Vopr Virusol. 2011 Jul-Aug;56(4):14-8. Russian.

PMID:
21899063
49.

Aprotinin and similar protease inhibitors as drugs against influenza.

Zhirnov OP, Klenk HD, Wright PF.

Antiviral Res. 2011 Oct;92(1):27-36. doi: 10.1016/j.antiviral.2011.07.014. Epub 2011 Jul 23. Review.

PMID:
21802447
50.

[Aprotinin-induced inhibition of pandemic influenza virus A(H1N1) reproduction].

Zhirnov OP, Klenk HD.

Vopr Virusol. 2011 May-Jun;56(3):24-8. Russian.

PMID:
21786623

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