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Items: 15

1.

Photodynamic cancer therapy enhances accumulation of nanoparticles in tumor-associated myeloid cells.

Huis In 't Veld RV, Ritsma L, Kleinovink JW, Que I, Ossendorp F, Cruz LJ.

J Control Release. 2019 Dec 31;320:19-31. doi: 10.1016/j.jconrel.2019.12.052. [Epub ahead of print]

2.

A Dual-Color Bioluminescence Reporter Mouse for Simultaneous in vivo Imaging of T Cell Localization and Function.

Kleinovink JW, Mezzanotte L, Zambito G, Fransen MF, Cruz LJ, Verbeek JS, Chan A, Ossendorp F, Löwik C.

Front Immunol. 2019 Jan 8;9:3097. doi: 10.3389/fimmu.2018.03097. eCollection 2018.

3.

Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication.

Zom GG, Willems MMJHP, Khan S, van der Sluis TC, Kleinovink JW, Camps MGM, van der Marel GA, Filippov DV, Melief CJM, Ossendorp F.

J Immunother Cancer. 2018 Dec 12;6(1):146. doi: 10.1186/s40425-018-0455-2.

4.

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS.

J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9.

5.

Photodynamic-Immune Checkpoint Therapy Eradicates Local and Distant Tumors by CD8+ T Cells.

Kleinovink JW, Fransen MF, Löwik CW, Ossendorp F.

Cancer Immunol Res. 2017 Oct;5(10):832-838. doi: 10.1158/2326-6066.CIR-17-0055. Epub 2017 Aug 29.

6.

PD-L1 immune suppression in cancer: Tumor cells or host cells?

Kleinovink JW, van Hall T, Ossendorp F, Fransen MF.

Oncoimmunology. 2017 May 12;6(7):e1325982. doi: 10.1080/2162402X.2017.1325982. eCollection 2017.

7.

PD-L1 expression on malignant cells is no prerequisite for checkpoint therapy.

Kleinovink JW, Marijt KA, Schoonderwoerd MJA, van Hall T, Ossendorp F, Fransen MF.

Oncoimmunology. 2017 Feb 21;6(4):e1294299. doi: 10.1080/2162402X.2017.1294299. eCollection 2017.

8.

Combination of Photodynamic Therapy and Specific Immunotherapy Efficiently Eradicates Established Tumors.

Kleinovink JW, van Driel PB, Snoeks TJ, Prokopi N, Fransen MF, Cruz LJ, Mezzanotte L, Chan A, Löwik CW, Ossendorp F.

Clin Cancer Res. 2016 Mar 15;22(6):1459-68. doi: 10.1158/1078-0432.CCR-15-0515. Epub 2015 Nov 6.

9.

Particulate Systems Based on Poly(Lactic-co-Glycolic)Acid (pLGA) for Immunotherapy of Cancer.

Rahimian S, Fransen MF, Kleinovink JW, Amidi M, Ossendorp F, Hennink WE.

Curr Pharm Des. 2015;21(29):4201-16. Review.

PMID:
26323429
10.

Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer.

Rahimian S, Fransen MF, Kleinovink JW, Amidi M, Ossendorp F, Hennink WE.

Biomaterials. 2015 Aug;61:33-40. doi: 10.1016/j.biomaterials.2015.04.043. Epub 2015 May 17.

PMID:
25993015
11.

Polymeric nanoparticles for co-delivery of synthetic long peptide antigen and poly IC as therapeutic cancer vaccine formulation.

Rahimian S, Fransen MF, Kleinovink JW, Christensen JR, Amidi M, Hennink WE, Ossendorp F.

J Control Release. 2015 Apr 10;203:16-22. doi: 10.1016/j.jconrel.2015.02.006. Epub 2015 Feb 7.

PMID:
25660830
12.

Near-infrared labeled, ovalbumin loaded polymeric nanoparticles based on a hydrophilic polyester as model vaccine: In vivo tracking and evaluation of antigen-specific CD8(+) T cell immune response.

Rahimian S, Kleinovink JW, Fransen MF, Mezzanotte L, Gold H, Wisse P, Overkleeft H, Amidi M, Jiskoot W, Löwik CW, Ossendorp F, Hennink WE.

Biomaterials. 2015 Jan;37:469-77. doi: 10.1016/j.biomaterials.2014.10.043. Epub 2014 Oct 28.

PMID:
25453974
13.

Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8(+) T cell response: a comparative study.

Cruz LJ, Rosalia RA, Kleinovink JW, Rueda F, Löwik CW, Ossendorp F.

J Control Release. 2014 Oct 28;192:209-18. doi: 10.1016/j.jconrel.2014.07.040. Epub 2014 Jul 25.

PMID:
25068703
14.

A Blk-p190RhoGAP signaling module downstream of activated Gα13 functionally opposes CXCL12-stimulated RhoA activation and cell invasion.

Bartolomé RA, Díaz-Martínez M, Coló GP, Arellano-Sánchez N, Torres-Ayuso P, Kleinovink JW, Mérida I, Teixidó J.

Cell Signal. 2014 Nov;26(11):2551-61. doi: 10.1016/j.cellsig.2014.07.008. Epub 2014 Jul 13.

PMID:
25025568
15.

Limited expression of heparan sulphate proteoglycans associated with Aβ deposits in the APPswe/PS1dE9 mouse model for Alzheimer's disease.

Timmer NM, Herbert MK, Kleinovink JW, Kiliaan AJ, De Waal RM, Verbeek MM.

Neuropathol Appl Neurobiol. 2010 Oct;36(6):478-86. doi: 10.1111/j.1365-2990.2010.01091.x.

PMID:
20831743

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