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Items: 26

1.

Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination.

Calabretta S, Vogel G, Yu Z, Choquet K, Darbelli L, Nicholson TB, Kleinman CL, Richard S.

Dev Cell. 2018 Aug 20;46(4):426-440.e5. doi: 10.1016/j.devcel.2018.06.025. Epub 2018 Jul 26.

PMID:
30057274
2.

Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance.

Ha JR, Ahn R, Smith HW, Sabourin V, Hébert S, Cepeda Cañedo E, Im YK, Kleinman CL, Muller WJ, Ursini-Siegel J.

Mol Cancer Res. 2018 May;16(5):894-908. doi: 10.1158/1541-7786.MCR-17-0623. Epub 2018 Feb 16.

PMID:
29453318
3.

chromswitch: a flexible method to detect chromatin state switches.

Jessa S, Kleinman CL.

Bioinformatics. 2018 Jul 1;34(13):2286-2288. doi: 10.1093/bioinformatics/bty075.

4.

Transcriptome profiling in preadipocytes identifies long noncoding RNAs as Sam68 targets.

Li N, Hébert S, Song J, Kleinman CL, Richard S.

Oncotarget. 2017 May 11;8(47):81994-82005. doi: 10.18632/oncotarget.17813. eCollection 2017 Oct 10.

5.

H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.

Pathania M, De Jay N, Maestro N, Harutyunyan AS, Nitarska J, Pahlavan P, Henderson S, Mikael LG, Richard-Londt A, Zhang Y, Costa JR, Hébert S, Khazaei S, Ibrahim NS, Herrero J, Riccio A, Albrecht S, Ketteler R, Brandner S, Kleinman CL, Jabado N, Salomoni P.

Cancer Cell. 2017 Nov 13;32(5):684-700.e9. doi: 10.1016/j.ccell.2017.09.014. Epub 2017 Oct 26.

PMID:
29107533
6.

A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer.

Savage P, Blanchet-Cohen A, Revil T, Badescu D, Saleh SMI, Wang YC, Zuo D, Liu L, Bertos NR, Munoz-Ramos V, Basik M, Petrecca K, Asselah J, Meterissian S, Guiot MC, Omeroglu A, Kleinman CL, Park M, Ragoussis J.

Cell Rep. 2017 Oct 31;21(5):1140-1149. doi: 10.1016/j.celrep.2017.10.015.

7.

Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.

Salloum R, McConechy MK, Mikael LG, Fuller C, Drissi R, DeWire M, Nikbakht H, De Jay N, Yang X, Boue D, Chow LML, Finlay JL, Gayden T, Karamchandani J, Hummel TR, Olshefski R, Osorio DS, Stevenson C, Kleinman CL, Majewski J, Fouladi M, Jabado N.

Acta Neuropathol Commun. 2017 Oct 30;5(1):78. doi: 10.1186/s40478-017-0479-8.

8.

Transcriptome profiling of mouse brains with qkI-deficient oligodendrocytes reveals major alternative splicing defects including self-splicing.

Darbelli L, Choquet K, Richard S, Kleinman CL.

Sci Rep. 2017 Aug 8;7(1):7554. doi: 10.1038/s41598-017-06211-1.

9.

Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation.

Choquet K, Yang S, Moir RD, Forget D, Larivière R, Bouchard A, Poitras C, Sgarioto N, Dicaire MJ, Noohi F, Kennedy TE, Rochford J, Bernard G, Teichmann M, Coulombe B, Willis IM, Kleinman CL, Brais B.

Mol Brain. 2017 Apr 13;10(1):13. doi: 10.1186/s13041-017-0294-y.

10.

ChIP-seq analysis of the LuxR-type regulator VjbR reveals novel insights into the Brucella virulence gene expression network.

Kleinman CL, Sycz G, Bonomi HR, Rodríguez RM, Zorreguieta A, Sieira R.

Nucleic Acids Res. 2017 Jun 2;45(10):5757-5769. doi: 10.1093/nar/gkx165.

11.

Gene networks show associations with seed region connectivity.

Forest M, Iturria-Medina Y, Goldman JS, Kleinman CL, Lovato A, Oros Klein K, Evans A, Ciampi A, Labbe A, Greenwood CMT.

Hum Brain Mapp. 2017 Jun;38(6):3126-3140. doi: 10.1002/hbm.23579. Epub 2017 Mar 21.

PMID:
28321948
12.

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.

Ahn R, Sabourin V, Bolt AM, Hébert S, Totten S, De Jay N, Festa MC, Young YK, Im YK, Pawson T, Koromilas AE, Muller WJ, Mann KK, Kleinman CL, Ursini-Siegel J.

Nat Commun. 2017 Mar 9;8:14638. doi: 10.1038/ncomms14638.

13.

A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.

Antonicka H, Choquet K, Lin ZY, Gingras AC, Kleinman CL, Shoubridge EA.

EMBO Rep. 2017 Jan;18(1):28-38. doi: 10.15252/embr.201643391. Epub 2016 Dec 14.

14.

Live single-cell laser tag.

Binan L, Mazzaferri J, Choquet K, Lorenzo LE, Wang YC, Affar el B, De Koninck Y, Ragoussis J, Kleinman CL, Costantino S.

Nat Commun. 2016 May 20;7:11636. doi: 10.1038/ncomms11636.

15.

NPM and BRG1 Mediate Transcriptional Resistance to Retinoic Acid in Acute Promyelocytic Leukemia.

Nichol JN, Galbraith MD, Kleinman CL, Espinosa JM, Miller WH Jr.

Cell Rep. 2016 Mar 29;14(12):2938-49. doi: 10.1016/j.celrep.2016.02.074. Epub 2016 Mar 17.

16.

Macrocyclic lactone resistance in Dirofilaria immitis: Failure of heartworm preventives and investigation of genetic markers for resistance.

Bourguinat C, Lee AC, Lizundia R, Blagburn BL, Liotta JL, Kraus MS, Keller K, Epe C, Letourneau L, Kleinman CL, Paterson T, Gomez EC, Montoya-Alonso JA, Smith H, Bhan A, Peregrine AS, Carmichael J, Drake J, Schenker R, Kaminsky R, Bowman DD, Geary TG, Prichard RK.

Vet Parasitol. 2015 Jun 15;210(3-4):167-78. doi: 10.1016/j.vetpar.2015.04.002. Epub 2015 Apr 13.

PMID:
25936435
17.

HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis.

Kleinman CL, Doria M, Orecchini E, Giuliani E, Galardi S, De Jay N, Michienzi A.

PLoS One. 2014 Dec 2;9(12):e113908. doi: 10.1371/journal.pone.0113908. eCollection 2014.

18.

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.

Kleinman CL, Gerges N, Papillon-Cavanagh S, Sin-Chan P, Pramatarova A, Quang DA, Adoue V, Busche S, Caron M, Djambazian H, Bemmo A, Fontebasso AM, Spence T, Schwartzentruber J, Albrecht S, Hauser P, Garami M, Klekner A, Bognar L, Montes JL, Staffa A, Montpetit A, Berube P, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel PM, Duchaine T, Perotti C, Fleming A, Faury D, Remke M, Gallo M, Dirks P, Taylor MD, Sladek R, Pastinen T, Chan JA, Huang A, Majewski J, Jabado N.

Nat Genet. 2014 Jan;46(1):39-44. doi: 10.1038/ng.2849. Epub 2013 Dec 8.

PMID:
24316981
19.

Polyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1.

Beaulieu YB, Kleinman CL, Landry-Voyer AM, Majewski J, Bachand F.

PLoS Genet. 2012;8(11):e1003078. doi: 10.1371/journal.pgen.1003078. Epub 2012 Nov 15.

20.

RNA editing of protein sequences: a rare event in human transcriptomes.

Kleinman CL, Adoue V, Majewski J.

RNA. 2012 Sep;18(9):1586-96. doi: 10.1261/rna.033233.112. Epub 2012 Jul 25.

21.

Comment on "Widespread RNA and DNA sequence differences in the human transcriptome".

Kleinman CL, Majewski J.

Science. 2012 Mar 16;335(6074):1302; author reply 1302. doi: 10.1126/science.1209658.

22.

RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression.

Lalonde E, Ha KC, Wang Z, Bemmo A, Kleinman CL, Kwan T, Pastinen T, Majewski J.

Genome Res. 2011 Apr;21(4):545-54. doi: 10.1101/gr.111211.110. Epub 2010 Dec 20.

23.

Statistical potentials for improved structurally constrained evolutionary models.

Kleinman CL, Rodrigue N, Lartillot N, Philippe H.

Mol Biol Evol. 2010 Jul;27(7):1546-60. doi: 10.1093/molbev/msq047. Epub 2010 Feb 16.

PMID:
20159780
24.

Fast optimization of statistical potentials for structurally constrained phylogenetic models.

Bonnard C, Kleinman CL, Rodrigue N, Lartillot N.

BMC Evol Biol. 2009 Sep 9;9:227. doi: 10.1186/1471-2148-9-227.

25.

Computational methods for evaluating phylogenetic models of coding sequence evolution with dependence between codons.

Rodrigue N, Kleinman CL, Philippe H, Lartillot N.

Mol Biol Evol. 2009 Jul;26(7):1663-76. doi: 10.1093/molbev/msp078. Epub 2009 Apr 21.

PMID:
19383983
26.

A maximum likelihood framework for protein design.

Kleinman CL, Rodrigue N, Bonnard C, Philippe H, Lartillot N.

BMC Bioinformatics. 2006 Jun 29;7:326.

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