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Items: 35

1.

High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity.

Willebrand R, Hamad I, Van Zeebroeck L, Kiss M, Bruderek K, Geuzens A, Swinnen D, Côrte-Real BF, Markó L, Lebegge E, Laoui D, Kemna J, Kammertoens T, Brandau S, Van Ginderachter JA, Kleinewietfeld M.

Front Immunol. 2019 Jun 4;10:1141. doi: 10.3389/fimmu.2019.01141. eCollection 2019.

2.

Sodium in the microenvironment regulates immune responses and tissue homeostasis.

Müller DN, Wilck N, Haase S, Kleinewietfeld M, Linker RA.

Nat Rev Immunol. 2019 Apr;19(4):243-254. doi: 10.1038/s41577-018-0113-4. Review.

PMID:
30644452
3.

Metabolic, Mental and Immunological Effects of Normoxic and Hypoxic Training in Multiple Sclerosis Patients: A Pilot Study.

Mähler A, Balogh A, Csizmadia I, Klug L, Kleinewietfeld M, Steiniger J, Šušnjar U, Müller DN, Boschmann M, Paul F.

Front Immunol. 2018 Nov 29;9:2819. doi: 10.3389/fimmu.2018.02819. eCollection 2018.

4.

Sodium chloride triggers Th17 mediated autoimmunity.

Haase S, Wilck N, Kleinewietfeld M, Müller DN, Linker RA.

J Neuroimmunol. 2019 Apr 15;329:9-13. doi: 10.1016/j.jneuroim.2018.06.016. Epub 2018 Jun 30. Review.

PMID:
29983198
5.

Interrelation of Diet, Gut Microbiome, and Autoantibody Production.

Petta I, Fraussen J, Somers V, Kleinewietfeld M.

Front Immunol. 2018 Mar 6;9:439. doi: 10.3389/fimmu.2018.00439. eCollection 2018. Review.

6.

The role of salt for immune cell function and disease.

Willebrand R, Kleinewietfeld M.

Immunology. 2018 Jul;154(3):346-353. doi: 10.1111/imm.12915. Epub 2018 Mar 24. Review.

7.

Western lifestyle and immunopathology of multiple sclerosis.

Matveeva O, Bogie JFJ, Hendriks JJA, Linker RA, Haghikia A, Kleinewietfeld M.

Ann N Y Acad Sci. 2018 Apr;1417(1):71-86. doi: 10.1111/nyas.13583. Epub 2018 Jan 27. Review.

8.

Salt-responsive gut commensal modulates TH17 axis and disease.

Wilck N, Matus MG, Kearney SM, Olesen SW, Forslund K, Bartolomaeus H, Haase S, Mähler A, Balogh A, Markó L, Vvedenskaya O, Kleiner FH, Tsvetkov D, Klug L, Costea PI, Sunagawa S, Maier L, Rakova N, Schatz V, Neubert P, Frätzer C, Krannich A, Gollasch M, Grohme DA, Côrte-Real BF, Gerlach RG, Basic M, Typas A, Wu C, Titze JM, Jantsch J, Boschmann M, Dechend R, Kleinewietfeld M, Kempa S, Bork P, Linker RA, Alm EJ, Müller DN.

Nature. 2017 Nov 30;551(7682):585-589. doi: 10.1038/nature24628. Epub 2017 Nov 15.

9.

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation.

Hammer A, Schliep A, Jörg S, Haghikia A, Gold R, Kleinewietfeld M, Müller DN, Linker RA.

J Neuroinflammation. 2017 Sep 12;14(1):184. doi: 10.1186/s12974-017-0954-y.

10.

Immunometabolic Regulation of Interleukin-17-Producing T Helper Cells: Uncoupling New Targets for Autoimmunity.

Binger KJ, Côrte-Real BF, Kleinewietfeld M.

Front Immunol. 2017 Mar 21;8:311. doi: 10.3389/fimmu.2017.00311. eCollection 2017. Review.

11.

Environmental factors in autoimmune diseases and their role in multiple sclerosis.

Jörg S, Grohme DA, Erzler M, Binsfeld M, Haghikia A, Müller DN, Linker RA, Kleinewietfeld M.

Cell Mol Life Sci. 2016 Dec;73(24):4611-4622. Epub 2016 Aug 4. Review.

12.

Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.

Arterbery AS, Osafo-Addo A, Avitzur Y, Ciarleglio M, Deng Y, Lobritto SJ, Martinez M, Hafler DA, Kleinewietfeld M, Ekong UD.

J Immunol. 2016 May 15;196(10):4040-51. doi: 10.4049/jimmunol.1502276. Epub 2016 Apr 18.

13.

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.

Haghikia A, Jörg S, Duscha A, Berg J, Manzel A, Waschbisch A, Hammer A, Lee DH, May C, Wilck N, Balogh A, Ostermann AI, Schebb NH, Akkad DA, Grohme DA, Kleinewietfeld M, Kempa S, Thöne J, Demir S, Müller DN, Gold R, Linker RA.

Immunity. 2016 Apr 19;44(4):951-3. doi: 10.1016/j.immuni.2016.04.006. No abstract available.

14.

High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells.

Jörg S, Kissel J, Manzel A, Kleinewietfeld M, Haghikia A, Gold R, Müller DN, Linker RA.

Exp Neurol. 2016 May;279:212-222. doi: 10.1016/j.expneurol.2016.03.010. Epub 2016 Mar 11.

PMID:
26976739
15.

Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells.

Hernandez AL, Kitz A, Wu C, Lowther DE, Rodriguez DM, Vudattu N, Deng S, Herold KC, Kuchroo VK, Kleinewietfeld M, Hafler DA.

J Clin Invest. 2015 Nov 2;125(11):4212-22. doi: 10.1172/JCI81151. Epub 2015 Oct 20.

16.

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.

Haghikia A, Jörg S, Duscha A, Berg J, Manzel A, Waschbisch A, Hammer A, Lee DH, May C, Wilck N, Balogh A, Ostermann AI, Schebb NH, Akkad DA, Grohme DA, Kleinewietfeld M, Kempa S, Thöne J, Demir S, Müller DN, Gold R, Linker RA.

Immunity. 2015 Oct 20;43(4):817-29. doi: 10.1016/j.immuni.2015.09.007. Erratum in: Immunity. 2016 Apr 19;44(4):951-3.

17.

High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.

Binger KJ, Gebhardt M, Heinig M, Rintisch C, Schroeder A, Neuhofer W, Hilgers K, Manzel A, Schwartz C, Kleinewietfeld M, Voelkl J, Schatz V, Linker RA, Lang F, Voehringer D, Wright MD, Hubner N, Dechend R, Jantsch J, Titze J, Müller DN.

J Clin Invest. 2015 Nov 2;125(11):4223-38. doi: 10.1172/JCI80919. Epub 2015 Oct 20.

18.

New role for the (pro)renin receptor in T-cell development.

Geisberger S, Maschke U, Gebhardt M, Kleinewietfeld M, Manzel A, Linker RA, Chidgey A, Dechend R, Nguyen G, Daumke O, Muller DN, Wright MD, Binger KJ.

Blood. 2015 Jul 23;126(4):504-7. doi: 10.1182/blood-2015-03-635292. Epub 2015 Jun 10.

19.

Sodium chloride, SGK1, and Th17 activation.

Binger KJ, Linker RA, Muller DN, Kleinewietfeld M.

Pflugers Arch. 2015 Mar;467(3):543-50. doi: 10.1007/s00424-014-1659-z. Epub 2014 Dec 4. Review.

PMID:
25471348
20.

Genetic and epigenetic fine mapping of causal autoimmune disease variants.

Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE.

Nature. 2015 Feb 19;518(7539):337-43. doi: 10.1038/nature13835. Epub 2014 Oct 29.

21.

Gut microbiota and the paradox of cancer immunotherapy.

Poutahidis T, Kleinewietfeld M, Erdman SE.

Front Immunol. 2014 Apr 7;5:157. doi: 10.3389/fimmu.2014.00157. eCollection 2014. Review.

22.

Regulatory T cells in autoimmune neuroinflammation.

Kleinewietfeld M, Hafler DA.

Immunol Rev. 2014 May;259(1):231-44. doi: 10.1111/imr.12169. Review.

23.

Role of "Western diet" in inflammatory autoimmune diseases.

Manzel A, Muller DN, Hafler DA, Erdman SE, Linker RA, Kleinewietfeld M.

Curr Allergy Asthma Rep. 2014 Jan;14(1):404. doi: 10.1007/s11882-013-0404-6. Review.

24.

The plasticity of human Treg and Th17 cells and its role in autoimmunity.

Kleinewietfeld M, Hafler DA.

Semin Immunol. 2013 Nov 15;25(4):305-12. doi: 10.1016/j.smim.2013.10.009. Epub 2013 Nov 5. Review.

25.

Microbial reprogramming inhibits Western diet-associated obesity.

Poutahidis T, Kleinewietfeld M, Smillie C, Levkovich T, Perrotta A, Bhela S, Varian BJ, Ibrahim YM, Lakritz JR, Kearney SM, Chatzigiagkos A, Hafler DA, Alm EJ, Erdman SE.

PLoS One. 2013 Jul 10;8(7):e68596. doi: 10.1371/journal.pone.0068596. Print 2013.

26.

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.

Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA.

Nature. 2013 Apr 25;496(7446):518-22. doi: 10.1038/nature11868. Epub 2013 Mar 6.

27.

Interferon-γ signaling inhibition ameliorates angiotensin II-induced cardiac damage.

Markó L, Kvakan H, Park JK, Qadri F, Spallek B, Binger KJ, Bowman EP, Kleinewietfeld M, Fokuhl V, Dechend R, Müller DN.

Hypertension. 2012 Dec;60(6):1430-6. doi: 10.1161/HYPERTENSIONAHA.112.199265. Epub 2012 Oct 29.

PMID:
23108651
28.

Induction and molecular signature of pathogenic TH17 cells.

Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK.

Nat Immunol. 2012 Oct;13(10):991-9. doi: 10.1038/ni.2416. Epub 2012 Sep 9.

29.

Vitamin D review.

Müller DN, Kleinewietfeld M, Kvakan H.

J Renin Angiotensin Aldosterone Syst. 2011 Jun;12(2):125-8. doi: 10.1177/1470320311410924. Review. No abstract available.

PMID:
21628362
30.

Regulatory T cells ameliorate angiotensin II-induced cardiac damage.

Kvakan H, Kleinewietfeld M, Qadri F, Park JK, Fischer R, Schwarz I, Rahn HP, Plehm R, Wellner M, Elitok S, Gratze P, Dechend R, Luft FC, Muller DN.

Circulation. 2009 Jun 9;119(22):2904-12. doi: 10.1161/CIRCULATIONAHA.108.832782. Epub 2009 May 26.

PMID:
19470887
31.

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.

Rötzschke O, Borsellino G, Battistini L, Falk K, Kleinewietfeld M.

Blood. 2009 Feb 26;113(9):2119-20; author reply 2120. doi: 10.1182/blood-2008-11-188847. No abstract available.

32.

CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells.

Kleinewietfeld M, Starke M, Di Mitri D, Borsellino G, Battistini L, Rötzschke O, Falk K.

Blood. 2009 Jan 22;113(4):827-36. doi: 10.1182/blood-2008-04-150524. Epub 2008 Oct 21.

33.

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

Borsellino G, Kleinewietfeld M, Di Mitri D, Sternjak A, Diamantini A, Giometto R, Höpner S, Centonze D, Bernardi G, Dell'Acqua ML, Rossini PM, Battistini L, Rötzschke O, Falk K.

Blood. 2007 Aug 15;110(4):1225-32. Epub 2007 Apr 20.

34.

CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.

Kleinewietfeld M, Puentes F, Borsellino G, Battistini L, Rötzschke O, Falk K.

Blood. 2005 Apr 1;105(7):2877-86. Epub 2004 Dec 21.

35.

Contribution of receptor editing to the antibody repertoire.

Casellas R, Shih TA, Kleinewietfeld M, Rakonjac J, Nemazee D, Rajewsky K, Nussenzweig MC.

Science. 2001 Feb 23;291(5508):1541-4.

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