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Items: 1 to 50 of 1554

1.

Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for thiopurine dosing based on TPMT and NUDT15 genotypes: 2018 update.

Relling MV, Schwab M, Whirl-Carrillo M, Suarez-Kurtz G, Pui CH, Stein CM, Moyer AM, Evans WE, Klein TE, Antillon-Klussmann FG, Caudle KE, Kato M, Yeoh AEJ, Schmiegelow K, Yang JJ.

Clin Pharmacol Ther. 2018 Nov 17. doi: 10.1002/cpt.1304. [Epub ahead of print]

PMID:
30447069
2.

Development of a multiplexed giant magnetoresistive biosensor array prototype to quantify ovarian cancer biomarkers.

Klein T, Wang W, Yu L, Wu K, Boylan KLM, Vogel RI, Skubitz APN, Wang JP.

Biosens Bioelectron. 2018 Oct 23;126:301-307. doi: 10.1016/j.bios.2018.10.046. [Epub ahead of print]

PMID:
30445305
3.

Climate change drives tree mortality.

Klein T, Hartmann H.

Science. 2018 Nov 16;362(6416):758. doi: 10.1126/science.aav6508. No abstract available.

PMID:
30442795
4.

The impact of blood pressure variability and pulse pressure on graft survival and mortality after kidney transplantation.

Pagonas N, Markakis K, Bauer F, Seibert FS, Seidel M, Zidek W, Kykalos S, Sasko B, Klein T, Babel N, Viebahn R, Westhoff TH.

Clin Transplant. 2018 Nov 14:e13448. doi: 10.1111/ctr.13448. [Epub ahead of print]

PMID:
30427068
5.

Essential characteristics of pharmacogenomics study publications.

Thorn CF, Whirl-Carrillo M, Hachad H, Johnson JA, McDonagh EM, Ratain MJ, Relling MV, Scott SA, Altman RB, Klein TE.

Clin Pharmacol Ther. 2018 Nov 8. doi: 10.1002/cpt.1279. [Epub ahead of print] Review.

PMID:
30406943
6.

Unusual Interplay between Superconductivity and Field-Induced Charge Order in YBa_{2}Cu_{3}O_{y}.

Kačmarčík J, Vinograd I, Michon B, Rydh A, Demuer A, Zhou R, Mayaffre H, Liang R, Hardy WN, Bonn DA, Doiron-Leyraud N, Taillefer L, Julien MH, Marcenat C, Klein T.

Phys Rev Lett. 2018 Oct 19;121(16):167002. doi: 10.1103/PhysRevLett.121.167002.

PMID:
30387647
8.

Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation.

Marshall NC, Klein T, Thejoe M, von Krosigk N, Kizhakkedathu J, Finlay BB, Overall CM.

J Proteome Res. 2018 Oct 29. doi: 10.1021/acs.jproteome.8b00675. [Epub ahead of print]

PMID:
30371095
9.

TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations.

Mallia-Milanes B, Dufour A, Philp C, Solis N, Klein T, Fischer M, Bolton CE, Shapiro SD, Overall CM, Johnson SR.

Am J Physiol Lung Cell Mol Physiol. 2018 Oct 4. doi: 10.1152/ajplung.00175.2018. [Epub ahead of print]

PMID:
30284925
10.

Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning.

Armstrong JPK, Puetzer JL, Serio A, Guex AG, Kapnisi M, Breant A, Zong Y, Assal V, Skaalure SC, King O, Murty T, Meinert C, Franklin AC, Bassindale PG, Nichols MK, Terracciano CM, Hutmacher DW, Drinkwater BW, Klein TJ, Perriman AW, Stevens MM.

Adv Mater. 2018 Oct;30(43):e1802649. doi: 10.1002/adma.201802649. Epub 2018 Sep 12.

PMID:
30277617
11.

Circuit quantum electrodynamics of granular aluminum resonators.

Maleeva N, Grünhaupt L, Klein T, Levy-Bertrand F, Dupre O, Calvo M, Valenti F, Winkel P, Friedrich F, Wernsdorfer W, Ustinov AV, Rotzinger H, Monfardini A, Fistul MV, Pop IM.

Nat Commun. 2018 Sep 24;9(1):3889. doi: 10.1038/s41467-018-06386-9.

12.

Multiscale Molecular Visualization.

Miao H, Klein T, Kouřil D, Mindek P, Schatz K, Gröller ME, Kozlíková B, Isenberg T, Viola I.

J Mol Biol. 2018 Sep 15. pii: S0022-2836(18)31049-0. doi: 10.1016/j.jmb.2018.09.004. [Epub ahead of print] Review.

PMID:
30227136
13.

PharmGKB summary: oxycodone pathway, pharmacokinetics.

Huddart R, Clarke M, Altman RB, Klein TE.

Pharmacogenet Genomics. 2018 Oct;28(10):230-237. doi: 10.1097/FPC.0000000000000351. No abstract available.

PMID:
30222708
14.

Molecular Basis for Immunity Protein Recognition of a Type VII Secretion System Exported Antibacterial Toxin.

Klein TA, Pazos M, Surette MG, Vollmer W, Whitney JC.

J Mol Biol. 2018 Oct 19;430(21):4344-4358. doi: 10.1016/j.jmb.2018.08.027. Epub 2018 Sep 5.

15.

PharmGKB summary: clozapine pathway, pharmacokinetics.

Thorn CF, Müller DJ, Altman RB, Klein TE.

Pharmacogenet Genomics. 2018 Sep;28(9):214-222. doi: 10.1097/FPC.0000000000000347. No abstract available.

PMID:
30134346
17.

Tree growth and water-use in hyper-arid Acacia occurs during the hottest and driest season.

Winters G, Otieno D, Cohen S, Bogner C, Ragowloski G, Paudel I, Klein T.

Oecologia. 2018 Nov;188(3):695-705. doi: 10.1007/s00442-018-4250-z. Epub 2018 Aug 18.

PMID:
30120548
18.

Nurse practitioners' recommendations for pharmacotherapy in the management of adolescent concussion.

Graves JM, Klein TA, Panther SG, Moore M, Abshire D, Graham J.

J Am Assoc Nurse Pract. 2018 Sep;30(9):499-510. doi: 10.1097/JXX.0000000000000070.

PMID:
30113534
19.

Malaria control and chemoprophylaxis policy in the Republic of Korea Armed Forces for the previous 20 years (1997-2016).

Im JH, Huh K, Yoon CG, Woo H, Lee JS, Chung MH, Klein TA, Jung J.

Malar J. 2018 Aug 15;17(1):295. doi: 10.1186/s12936-018-2449-4.

20.

Molecular characterization of Haemaphysalis longicornis-borne rickettsiae, Republic of Korea and China.

Jiang J, An H, Lee JS, O'Guinn ML, Kim HC, Chong ST, Zhang Y, Song D, Burrus RG, Bao Y, Klein TA, Richards AL.

Ticks Tick Borne Dis. 2018 Sep;9(6):1606-1613. doi: 10.1016/j.ttbdis.2018.07.013. Epub 2018 Jul 29.

PMID:
30100386
21.

Anti-angiogenic effects of the DPP-4 inhibitor linagliptin via inhibition of VEGFR signalling in the mouse model of oxygen-induced retinopathy.

Kolibabka M, Dietrich N, Klein T, Hammes HP.

Diabetologia. 2018 Nov;61(11):2412-2421. doi: 10.1007/s00125-018-4701-4. Epub 2018 Aug 10.

PMID:
30097694
22.

P 171 - Immediate effect of retrocapital bars of sensorimotor insoles on the foot progression angle in asymptomatic healthy adults.

Lastovicka O, Klein T, Janura M.

Gait Posture. 2018 Sep;65 Suppl 1:525. doi: 10.1016/j.gaitpost.2018.07.092. Epub 2018 Jul 17. No abstract available.

PMID:
30072083
23.

P 170- Effect of sensorimotor foot orthoses on kinematics of knee.

Klein T, Laštovička O, Janura M, Richards J.

Gait Posture. 2018 Sep;65 Suppl 1:524. doi: 10.1016/j.gaitpost.2018.07.091. Epub 2018 Jul 17. No abstract available.

PMID:
30072080
24.

Media photo-degradation in pharmaceutical biotechnology - impact of ambient light on media quality, cell physiology, and IgG production in CHO cultures.

Neutsch L, Kroll P, Brunner M, Pansy A, Kovar M, Herwig C, Klein T.

J Chem Technol Biotechnol. 2018 Aug;93(8):2141-2151. doi: 10.1002/jctb.5643. Epub 2018 Jun 1.

25.

Breadth of coverage against a panel of 110 invasive disease isolates, immunogenicity and safety for 2 and 3 doses of an investigational MenABCWY vaccine in US adolescents - Results from a randomized, controlled, observer-blind phase II study.

Welsch JA, Senders S, Essink B, Klein T, Smolenov I, Pedotti P, Barbi S, Verma B, Toneatto D.

Vaccine. 2018 Aug 23;36(35):5309-5317. doi: 10.1016/j.vaccine.2018.07.016. Epub 2018 Jul 27.

26.

The Cologne pouch procedure for continent anal urinary diversion in children with bladder exstrophy-epispadias complex.

Klein T, Winkler A, Vahdad RM, Ekamp A, Boemers TM.

J Pediatr Urol. 2018 Jul 3. pii: S1477-5131(18)30327-9. doi: 10.1016/j.jpurol.2018.06.007. [Epub ahead of print]

PMID:
30031742
27.

Differences in kidney-specific DPP-4 inhibition by linagliptin and sitagliptin.

Luippold G, Mark M, Klein T, Amann K, Daniel C.

Diabetes Res Clin Pract. 2018 Sep;143:199-203. doi: 10.1016/j.diabres.2018.07.009. Epub 2018 Jul 18.

PMID:
30031047
28.

Endocytic Trafficking of the Notch Receptor.

Schnute B, Troost T, Klein T.

Adv Exp Med Biol. 2018;1066:99-122. doi: 10.1007/978-3-319-89512-3_6.

PMID:
30030824
29.

Effects of rule uncertainty on cognitive flexibility in a card-sorting paradigm.

Lange F, Kip A, Klein T, Müller D, Seer C, Kopp B.

Acta Psychol (Amst). 2018 Oct;190:53-64. doi: 10.1016/j.actpsy.2018.07.002. Epub 2018 Jul 13.

PMID:
30015136
30.

Substitutions for arginine at position 780 in triple helical domain of the α1(I) chain alter folding of the type I procollagen molecule and cause osteogenesis imperfecta.

Makareeva E, Sun G, Mirigian LS, Mertz EL, Vera JC, Espinoza NA, Yang K, Chen D, Klein TE, Byers PH, Leikin S.

PLoS One. 2018 Jul 10;13(7):e0200264. doi: 10.1371/journal.pone.0200264. eCollection 2018.

31.

Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.

Spencer NY, Yang Z, Sullivan JC, Klein T, Stanton RC.

PLoS One. 2018 Jul 6;13(7):e0200249. doi: 10.1371/journal.pone.0200249. eCollection 2018.

32.

Electronic conduction during the formation stages of a single-molecule junction.

Pal AN, Klein T, Vilan A, Tal O.

Beilstein J Nanotechnol. 2018 May 17;9:1471-1477. doi: 10.3762/bjnano.9.138. eCollection 2018.

33.

Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.

Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, Franzke CW, Overall CM, Granville DJ.

Sci Rep. 2018 Jun 26;8(1):9690. doi: 10.1038/s41598-018-28070-0.

34.

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

Dufour A, Bellac CL, Eckhard U, Solis N, Klein T, Kappelhoff R, Fortelny N, Jobin P, Rozmus J, Mark J, Pavlidis P, Dive V, Barbour SJ, Overall CM.

Nat Commun. 2018 Jun 20;9(1):2416. doi: 10.1038/s41467-018-04717-4.

35.

Assessment of pain quality reveals distinct differences between nociceptive innervation of low back fascia and muscle in humans.

Schilder A, Magerl W, Klein T, Treede RD.

Pain Rep. 2018 May 30;3(3):e662. doi: 10.1097/PR9.0000000000000662. eCollection 2018 May.

36.

Standardization can accelerate the adoption of pharmacogenomics: current status and the path forward.

Caudle KE, Keeling NJ, Klein TE, Whirl-Carrillo M, Pratt VM, Hoffman JM.

Pharmacogenomics. 2018 Jul 1;19(10):847-860. doi: 10.2217/pgs-2018-0028. Epub 2018 Jun 19.

PMID:
29914287
37.

Influence of Liquid Structure on Fickian Diffusion in Binary Mixtures of n-Hexane and Carbon Dioxide Probed by Dynamic Light Scattering, Raman Spectroscopy, and Molecular Dynamics Simulations.

Klein T, Wu W, Rausch MH, Giraudet C, Koller TM, Fröba AP.

J Phys Chem B. 2018 Jul 19;122(28):7122-7133. doi: 10.1021/acs.jpcb.8b03568. Epub 2018 Jul 3.

PMID:
29889520
38.

Urban Rodent Surveillance, Climatic Association, and Genomic Characterization of Seoul Virus Collected at U.S. Army Garrison, Seoul, Republic of Korea, 2006-2010.

Kim HC, Kim WK, No JS, Lee SH, Gu SH, Chong ST, Klein TA, Song JW.

Am J Trop Med Hyg. 2018 Aug;99(2):470-476. doi: 10.4269/ajtmh.17-0459. Epub 2018 May 31.

PMID:
29869603
39.

In vitro biomimetic engineering of a human hematopoietic niche with functional properties.

Bourgine PE, Klein T, Paczulla AM, Shimizu T, Kunz L, Kokkaliaris KD, Coutu DL, Lengerke C, Skoda R, Schroeder T, Martin I.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5688-E5695. doi: 10.1073/pnas.1805440115. Epub 2018 Jun 4.

PMID:
29866839
40.

Introduction to four reviews addressing critical topics identified by the 2015 Nurse Practitioner Research Agenda Roundtable: Priorities for policy, workforce, education, and practice.

Buchholz SW, Klein T, Cooke C, Cook ML, Knestrick J, Dickins K.

J Am Assoc Nurse Pract. 2018 May 4. doi: 10.1097/JXX.0000000000000035. [Epub ahead of print]

PMID:
29846306
41.

Searching for the best real-time RT-PCRs to detect Zika virus infections: the importance of comparing several protocols.

de Moraes FM, Espósito DLA, Klein TM, da Fonseca BAL.

Braz J Med Biol Res. 2018;51(6):e7221. doi: 10.1590/1414-431x20187221. Epub 2018 May 21.

42.

A Method for Prostate and Breast Cancer Cell Spheroid Cultures Using Gelatin Methacryloyl-Based Hydrogels.

Meinert C, Theodoropoulos C, Klein TJ, Hutmacher DW, Loessner D.

Methods Mol Biol. 2018;1786:175-194. doi: 10.1007/978-1-4939-7845-8_10.

PMID:
29786793
43.

The effect of DPP-4 inhibition to improve functional outcome after stroke is mediated by the SDF-1α/CXCR4 pathway.

Chiazza F, Tammen H, Pintana H, Lietzau G, Collino M, Nyström T, Klein T, Darsalia V, Patrone C.

Cardiovasc Diabetol. 2018 May 19;17(1):60. doi: 10.1186/s12933-018-0702-3.

44.

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).

Bergmeijer TO, Reny JL, Pakyz RE, Gong L, Lewis JP, Kim EY, Aradi D, Fernandez-Cadenas I, Horenstein RB, Lee MTM, Whaley RM, Montaner J, Gensini GF, Cleator JH, Chang K, Holmvang L, Hochholzer W, Roden DM, Winter S, Altman RB, Alexopoulos D, Kim HS, Déry JP, Gawaz M, Bliden K, Valgimigli M, Marcucci R, Campo G, Schaeffeler E, Dridi NP, Wen MS, Shin JG, Simon T, Fontana P, Giusti B, Geisler T, Kubo M, Trenk D, Siller-Matula JM, Ten Berg JM, Gurbel PA, Hulot JS, Mitchell BD, Schwab M, Ritchie MD, Klein TE, Shuldiner AR; ICPC Investigators.

Am Heart J. 2018 Apr;198:152-159. doi: 10.1016/j.ahj.2017.12.010. Epub 2017 Dec 17.

PMID:
29653637
45.

Pharmacogenomics and big genomic data: from lab to clinic and back again.

Lavertu A, McInnes G, Daneshjou R, Whirl-Carrillo M, Klein TE, Altman RB.

Hum Mol Genet. 2018 May 1;27(R1):R72-R78. doi: 10.1093/hmg/ddy116.

PMID:
29635477
46.

The human pain system exhibits higher-order plasticity (metaplasticity).

Magerl W, Hansen N, Treede RD, Klein T.

Neurobiol Learn Mem. 2018 Oct;154:112-120. doi: 10.1016/j.nlm.2018.04.003. Epub 2018 Apr 6.

PMID:
29631001
47.

Gaussian process uncertainty in age estimation as a measure of brain abnormality.

Gutierrez Becker B, Klein T, Wachinger C; Alzheimer’s Disease Neuroimaging Initiative and the Australian Imaging Biomarkers and Lifestyle flagship study of ageing.

Neuroimage. 2018 Jul 15;175:246-258. doi: 10.1016/j.neuroimage.2018.03.075. Epub 2018 Apr 5.

PMID:
29627589
48.

Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.

Amare AT, Schubert KO, Tekola-Ayele F, Hsu YH, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Kato M, Liu YL, Praphanphoj V, Stingl JC, Bobo WV, Tsai SJ, Kubo M, Klein TE, Weinshilboum RM, Biernacka JM, Baune BT.

Front Psychiatry. 2018 Mar 6;9:65. doi: 10.3389/fpsyt.2018.00065. eCollection 2018.

49.

Physical Exercise and Spatial Training: A Longitudinal Study of Effects on Cognition, Growth Factors, and Hippocampal Plasticity.

Woost L, Bazin PL, Taubert M, Trampel R, Tardif CL, Garthe A, Kempermann G, Renner U, Stalla G, Ott DVM, Rjosk V, Obrig H, Villringer A, Roggenhofer E, Klein TA.

Sci Rep. 2018 Mar 9;8(1):4239. doi: 10.1038/s41598-018-19993-9.

50.

PharmGKB summary: clobazam pathway, pharmacokinetics.

Huddart R, Leeder JS, Altman RB, Klein TE.

Pharmacogenet Genomics. 2018 Apr;28(4):110-115. doi: 10.1097/FPC.0000000000000327. No abstract available.

PMID:
29517622

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