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Items: 1 to 50 of 206

1.

Compassion cultivation training promotes medical student wellness and enhanced clinical care.

Weingartner LA, Sawning S, Shaw MA, Klein JB.

BMC Med Educ. 2019 May 10;19(1):139. doi: 10.1186/s12909-019-1546-6.

2.

CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease.

Mariani LH, Bomback AS, Canetta PA, Flessner MF, Helmuth M, Hladunewich MA, Hogan JJ, Kiryluk K, Nachman PH, Nast CC, Rheault MN, Rizk DV, Trachtman H, Wenderfer SE, Bowers C, Hill-Callahan P, Marasa M, Poulton CJ, Revell A, Vento S, Barisoni L, Cattran D, D'Agati V, Jennette JC, Klein JB, Laurin LP, Twombley K, Falk RJ, Gharavi AG, Gillespie BW, Gipson DS, Greenbaum LA, Holzman LB, Kretzler M, Robinson B, Smoyer WE, Guay-Woodford LM; CureGN Consortium.

Am J Kidney Dis. 2019 Feb;73(2):218-229. doi: 10.1053/j.ajkd.2018.07.020. Epub 2018 Nov 9.

PMID:
30420158
3.

Precision medicine in lupus nephritis: can biomarkers get us there?

Caster DJ, Merchant ML, Klein JB, Powell DW.

Transl Res. 2018 Nov;201:26-39. doi: 10.1016/j.trsl.2018.08.002. Epub 2018 Aug 10. Review.

PMID:
30179587
4.

Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes.

Looker HC, Merchant ML, Rane MJ, Nelson RG, Kimmel PL, Rovin BH, Klein JB, Mauer M; CKD Biomarkers Consortium.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1484-F1492. doi: 10.1152/ajprenal.00183.2018. Epub 2018 Aug 22.

PMID:
30132343
5.

Poly-ubiquitin profile in Alzheimer disease brain.

Tramutola A, Triani F, Di Domenico F, Barone E, Cai J, Klein JB, Perluigi M, Butterfield DA.

Neurobiol Dis. 2018 Oct;118:129-141. doi: 10.1016/j.nbd.2018.07.006. Epub 2018 Jul 9.

PMID:
30003951
6.

Anti-hyperalgesic effects of two sphingosine derivatives in different acute and chronic models of hyperalgesia in mice.

Cavichioli FJ, Bernal GNB, Holzmann I, Klein JB, Escarcena R, Del Olmo E, San Feliciano A, Cechinel Filho V, Quintão NLM.

Pharmacol Rep. 2018 Aug;70(4):753-759. doi: 10.1016/j.pharep.2018.02.018. Epub 2018 Feb 23.

PMID:
29936362
7.

Protein Mass Spectrometry Made Simple.

Klein JB, A Knepper M.

J Am Soc Nephrol. 2018 Jun;29(6):1585-1587. doi: 10.1681/ASN.2018030244. Epub 2018 May 3. No abstract available.

8.

Biomarker enhanced risk prediction for development of AKI after cardiac surgery.

Merchant ML, Brier ME, Slaughter MS, Klein JB, McLeish KR.

BMC Nephrol. 2018 May 2;19(1):102. doi: 10.1186/s12882-018-0902-9.

9.

Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery.

Merchant ML, Rood IM, Deegens JKJ, Klein JB.

Nat Rev Nephrol. 2017 Dec;13(12):731-749. doi: 10.1038/nrneph.2017.148. Epub 2017 Oct 30. Review.

10.

Common Elements in Rare Kidney Diseases: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Aymé S, Bockenhauer D, Day S, Devuyst O, Guay-Woodford LM, Ingelfinger JR, Klein JB, Knoers NVAM, Perrone RD, Roberts J, Schaefer F, Torres VE, Cheung M, Wheeler DC, Winkelmayer WC; Conference Participants.

Kidney Int. 2017 Oct;92(4):796-808. doi: 10.1016/j.kint.2017.06.018. Erratum in: Kidney Int. 2017 Dec;92(6):1558.

11.

The role of charge in the toxicity of polymer-coated cerium oxide nanomaterials to Caenorhabditis elegans.

Arndt DA, Oostveen EK, Triplett J, Butterfield DA, Tsyusko OV, Collin B, Starnes DL, Cai J, Klein JB, Nass R, Unrine JM.

Comp Biochem Physiol C Toxicol Pharmacol. 2017 Oct;201:1-10. doi: 10.1016/j.cbpc.2017.08.009. Epub 2017 Sep 6.

PMID:
28888877
12.

Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus.

Wheelock KM, Cai J, Looker HC, Merchant ML, Nelson RG, Fufaa GD, Weil EJ, Feldman HI, Vasan RS, Kimmel PL, Rovin BH, Mauer M, Klein JB; CKD Biomarkers Consortium.

PLoS One. 2017 Jul 10;12(7):e0180964. doi: 10.1371/journal.pone.0180964. eCollection 2017.

13.

Biomarkers of lupus nephritis histology and flare: deciphering the relevant amidst the noise.

Birmingham DJ, Merchant M, Waikar SS, Nagaraja H, Klein JB, Rovin BH.

Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i71-i79. doi: 10.1093/ndt/gfw300. Review.

14.

Applying proteomics to detect early signs of chronic kidney disease: where has the magic gone?

Klein JB.

Expert Rev Proteomics. 2017 May;14(5):387-390. doi: 10.1080/14789450.2017.1315303. Epub 2017 Apr 10. No abstract available.

PMID:
28363249
15.

Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function.

Swomley AM, Triplett JC, Keeney JT, Warrier G, Pearson KJ, Mattison JA, de Cabo R, Cai J, Klein JB, Butterfield DA.

J Nutr Biochem. 2017 Jan;39:169-179. doi: 10.1016/j.jnutbio.2016.10.006. Epub 2016 Oct 13.

16.

Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.

Triplett JC, Swomley AM, Kirk J, Grimes KM, Lewis KN, Orr ME, Rodriguez KA, Cai J, Klein JB, Buffenstein R, Butterfield DA.

Neurochem Res. 2016 Jul;41(7):1625-34. doi: 10.1007/s11064-016-1877-1. Epub 2016 Mar 2.

PMID:
26935741
17.

Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice.

Barati MT, Powell DW, Kechavarzi BD, Isaacs SM, Zheng S, Epstein PN, Cai L, Coventry S, Rane MJ, Klein JB.

Cell Stress Chaperones. 2016 Jan;21(1):155-166. doi: 10.1007/s12192-015-0648-2.

18.

Quantitative phosphoproteomic analyses of the inferior parietal lobule from three different pathological stages of Alzheimer's disease.

Triplett JC, Swomley AM, Cai J, Klein JB, Butterfield DA.

J Alzheimers Dis. 2016;49(1):45-62. doi: 10.3233/JAD-150417.

PMID:
26444780
19.

Proteomics Analysis of Molecular Risk Factors in the Ocular Hypertensive Human Retina.

Yang X, Hondur G, Li M, Cai J, Klein JB, Kuehn MH, Tezel G.

Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5816-30. doi: 10.1167/iovs.15-17294.

20.

Increased expression of lysosome membrane protein 2 in glomeruli of patients with idiopathic membranous nephropathy.

Rood IM, Merchant ML, Wilkey DW, Zhang T, Zabrouskov V, van der Vlag J, Dijkman HB, Willemsen BK, Wetzels JF, Klein JB, Deegens JK.

Proteomics. 2015 Nov;15(21):3722-30. doi: 10.1002/pmic.201500127. Epub 2015 Sep 28.

PMID:
26304790
21.

Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.

Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2213-24. doi: 10.1016/j.bbadis.2015.08.002. Epub 2015 Aug 4.

22.

Proteomics and autoimmune kidney disease.

Rovin BH, Klein JB.

Clin Immunol. 2015 Nov;161(1):23-30. doi: 10.1016/j.clim.2015.04.021. Epub 2015 May 13. Review.

23.

Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.

Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA.

J Neurochem. 2015 Aug;134(3):538-50. doi: 10.1111/jnc.13149. Epub 2015 Jun 3.

24.

Changing the concepts of immune-mediated glomerular diseases through proteomics.

Caster DJ, Hobeika L, Klein JB, Powell DW, McLeish KR.

Proteomics Clin Appl. 2015 Dec;9(11-12):967-71. doi: 10.1002/prca.201400159. Epub 2015 Jun 17. Review.

25.

Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators.

Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ.

PLoS One. 2015 Apr 7;10(4):e0121637. doi: 10.1371/journal.pone.0121637. eCollection 2015.

26.

Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis.

Caster DJ, Korte EA, Merchant ML, Klein JB, Wilkey DW, Rovin BH, Birmingham DJ, Harley JB, Cobb BL, Namjou B, McLeish KR, Powell DW.

Proteomics Clin Appl. 2015 Dec;9(11-12):1012-20. doi: 10.1002/prca.201400175. Epub 2015 Jun 12.

27.

Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium.

Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, Molitch ME, Nelsestuen GL, Rebholz CM, Rovin BH, Sabbisetti VS, Van Eyk JE, Vasan RS, Waikar SS, Whitehead KM, Nelson RG; CKD Biomarkers Consortium.

Clin J Am Soc Nephrol. 2015 May 7;10(5):894-902. doi: 10.2215/CJN.11541114. Epub 2015 Mar 4. Review.

28.

Cytoskeletal rearrangement and Src and PI-3K-dependent Akt activation control GABA(B)R-mediated chemotaxis.

Barati MT, Scherzer J, Wu R, Rane MJ, Klein JB.

Cell Signal. 2015 Jun;27(6):1178-1185. doi: 10.1016/j.cellsig.2015.02.022. Epub 2015 Feb 26.

29.

Urinary monocyte chemoattractant protein-1 and hepcidin and early diabetic nephropathy lesions in type 1 diabetes mellitus.

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Knowler WC, Rovin BH, Wu H, Klein JB, Mifflin TE, Feldman HI, Vasan RS, Kimmel PL, Kusek JW, Mauer M; CKD Biomarkers Consortium and the RASS Investigators.

Nephrol Dial Transplant. 2015 Apr;30(4):599-606. doi: 10.1093/ndt/gfv012. Epub 2015 Feb 3.

30.

Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease.

Triplett JC, Zhang Z, Sultana R, Cai J, Klein JB, Büeler H, Butterfield DA.

J Neurochem. 2015 Jun;133(5):750-65. doi: 10.1111/jnc.13039. Epub 2015 Mar 1.

31.

An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach.

Cenini G, Fiorini A, Sultana R, Perluigi M, Cai J, Klein JB, Head E, Butterfield DA.

Free Radic Biol Med. 2014 Nov;76:89-95. doi: 10.1016/j.freeradbiomed.2014.08.006. Epub 2014 Aug 20.

32.

Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment.

Zhao Y, Miriyala S, Miao L, Mitov M, Schnell D, Dhar SK, Cai J, Klein JB, Sultana R, Butterfield DA, Vore M, Batinic-Haberle I, Bondada S, St Clair DK.

Free Radic Biol Med. 2014 Jul;72:55-65. doi: 10.1016/j.freeradbiomed.2014.03.001. Epub 2014 Mar 12.

33.

Detection of cervical cancer biomarker patterns in blood plasma and urine by differential scanning calorimetry and mass spectrometry.

Garbett NC, Merchant ML, Helm CW, Jenson AB, Klein JB, Chaires JB.

PLoS One. 2014 Jan 8;9(1):e84710. doi: 10.1371/journal.pone.0084710. eCollection 2014.

34.

Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease.

Sultana R, Baglioni M, Cecchetti R, Cai J, Klein JB, Bastiani P, Ruggiero C, Mecocci P, Butterfield DA.

Free Radic Biol Med. 2013 Dec;65:595-606. doi: 10.1016/j.freeradbiomed.2013.08.001. Epub 2013 Aug 8.

35.

Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates.

Baba SP, Hoetker JD, Merchant M, Klein JB, Cai J, Barski OA, Conklin DJ, Bhatnagar A.

J Biol Chem. 2013 Sep 27;288(39):28163-79. doi: 10.1074/jbc.M113.504753. Epub 2013 Aug 8.

36.

Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline.

Keeney JTR, Förster S, Sultana R, Brewer LD, Latimer CS, Cai J, Klein JB, Porter NM, Butterfield DA.

Free Radic Biol Med. 2013 Dec;65:324-334. doi: 10.1016/j.freeradbiomed.2013.07.019. Epub 2013 Jul 18.

37.

Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study.

Fiorini A, Sultana R, Förster S, Perluigi M, Cenini G, Cini C, Cai J, Klein JB, Farr SA, Niehoff ML, Morley JE, Kumar VB, Butterfield DA.

Free Radic Biol Med. 2013 Dec;65:1-14. doi: 10.1016/j.freeradbiomed.2013.06.017. Epub 2013 Jun 15.

38.

Cytotoxic, antitumour and antimetastatic activity of two new polyacetylenes isolated from Vernonia scorpioides (Lam.) Pers.

Klein JB, Nowill AE, Franchi GC Jr, Biavatti MW, Quintão NL, de Freitas RA.

Basic Clin Pharmacol Toxicol. 2013 Nov;113(5):307-15. doi: 10.1111/bcpt.12098. Epub 2013 Jul 9.

39.

Calorimetric analysis of the plasma proteome: identification of type 1 diabetes patients with early renal function decline.

Garbett NC, Merchant ML, Chaires JB, Klein JB.

Biochim Biophys Acta. 2013 Oct;1830(10):4675-80. doi: 10.1016/j.bbagen.2013.05.007. Epub 2013 May 10.

40.

Technical note: proteomic approaches to fundamental questions about neutrophil biology.

McLeish KR, Merchant ML, Klein JB, Ward RA.

J Leukoc Biol. 2013 Oct;94(4):683-92. doi: 10.1189/jlb.1112591. Epub 2013 Mar 7. Review.

41.

Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type 1 diabetes.

Merchant ML, Niewczas MA, Ficociello LH, Lukenbill JA, Wilkey DW, Li M, Khundmiri SJ, Warram JH, Krolewski AS, Klein JB.

Kidney Int. 2013 Jun;83(6):1177-84. doi: 10.1038/ki.2013.8. Epub 2013 Mar 6.

42.

Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53.

Fiorini A, Sultana R, Barone E, Cenini G, Perluigi M, Mancuso C, Cai J, Klein JB, St Clair D, Butterfield DA.

PLoS One. 2012;7(11):e49846. doi: 10.1371/journal.pone.0049846. Epub 2012 Nov 27.

43.

New treatments for CKD--new insights into pathogenesis.

Lederer ED, Klein JB.

J Am Soc Nephrol. 2012 Oct;23(10):1601-3. Epub 2012 Sep 13. No abstract available.

44.

Days* - A bright future on solid foundations.

Catapano G, Klein JB.

Int J Artif Organs. 2012 Feb 11:0. doi: 10.5301/IJAO.2012.9030. [Epub ahead of print] No abstract available.

PMID:
22328331
45.

Elongin C is a mediator of Notch4 activity in human renal tubule cells.

Cummins TD, Mendenhall MD, Lowry MN, Korte EA, Barati MT, Khundmiri SJ, Salyer SA, Klein JB, Powell DW.

Biochim Biophys Acta. 2011 Dec;1814(12):1748-57. doi: 10.1016/j.bbapap.2011.09.010. Epub 2011 Oct 5.

46.

Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter.

Ahmad A, Khundmiri SJ, Pribble F, Merchant ML, Ameen M, Klein JB, Levi M, Lederer ED.

Cell Physiol Biochem. 2011;27(6):703-14. doi: 10.1159/000330079. Epub 2011 Jun 17.

47.

Ich denk' es war ein gutes Jahr* (Reinhard Mey, 1968)--the year 2010 balance.

Catapano G, Klein JB.

Int J Artif Organs. 2010 Dec;33(12):841-3. No abstract available.

PMID:
21186464
48.

Oncostatin M receptor β and cysteine/histidine-rich 1 are biomarkers of the response to erythropoietin in hemodialysis patients.

Merchant ML, Gaweda AE, Dailey AJ, Wilkey DW, Zhang X, Rovin BH, Klein JB, Brier ME.

Kidney Int. 2011 Mar;79(5):546-554. doi: 10.1038/ki.2010.468. Epub 2010 Dec 8.

49.

Microfiltration isolation of human urinary exosomes for characterization by MS.

Merchant ML, Powell DW, Wilkey DW, Cummins TD, Deegens JK, Rood IM, McAfee KJ, Fleischer C, Klein E, Klein JB.

Proteomics Clin Appl. 2010 Jan;4(1):84-96. doi: 10.1002/prca.200800093. Epub 2009 Nov 11.

PMID:
21137018
50.

Proteomic discovery of diabetic nephropathy biomarkers.

Merchant ML, Klein JB.

Adv Chronic Kidney Dis. 2010 Nov;17(6):480-6. doi: 10.1053/j.ackd.2010.09.001. Review.

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