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Items: 12


Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains.

Boija A, Klein IA, Sabari BR, Dall'Agnese A, Coffey EL, Zamudio AV, Li CH, Shrinivas K, Manteiga JC, Hannett NM, Abraham BJ, Afeyan LK, Guo YE, Rimel JK, Fant CB, Schuijers J, Lee TI, Taatjes DJ, Young RA.

Cell. 2018 Dec 13;175(7):1842-1855.e16. doi: 10.1016/j.cell.2018.10.042. Epub 2018 Nov 15.


Coactivator condensation at super-enhancers links phase separation and gene control.

Sabari BR, Dall'Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC, Li CH, Guo YE, Day DS, Schuijers J, Vasile E, Malik S, Hnisz D, Lee TI, Cisse II, Roeder RG, Sharp PA, Chakraborty AK, Young RA.

Science. 2018 Jul 27;361(6400). pii: eaar3958. doi: 10.1126/science.aar3958. Epub 2018 Jun 21.


Patient as Co-Teacher on Rounds: a Pilot Study.

Perez AA, Pelletier SR, Klein IA, Shields HM.

J Gen Intern Med. 2018 Jul;33(7):1010-1012. doi: 10.1007/s11606-018-4421-y. No abstract available.


The experience of an Academic League: the positive impact on knowledge about trauma and emergency.

Tedeschi LT, Rigolon LPJ, Mendes FO, Fischmann MM, Klein IA, Baltar VT.

Rev Col Bras Cir. 2018 Feb 19;45(1):e1482. doi: 10.1590/0100-6991e-20181482. English, Portuguese.


High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration.

Janovitz T, Klein IA, Oliveira T, Mukherjee P, Nussenzweig MC, Sadelain M, Falck-Pedersen E.

J Virol. 2013 Aug;87(15):8559-68. doi: 10.1128/JVI.01135-13. Epub 2013 May 29.


Activation-induced cytidine deaminase in antibody diversification and chromosome translocation.

Gazumyan A, Bothmer A, Klein IA, Nussenzweig MC, McBride KM.

Adv Cancer Res. 2012;113:167-90. doi: 10.1016/B978-0-12-394280-7.00005-1. Review.


Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements.

Oliveira TY, Resch W, Jankovic M, Casellas R, Nussenzweig MC, Klein IA.

J Immunol Methods. 2012 Jan 31;375(1-2):176-81. doi: 10.1016/j.jim.2011.10.007. Epub 2011 Oct 18.


Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC.

Cell. 2011 Sep 30;147(1):95-106. doi: 10.1016/j.cell.2011.07.048.


Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.

Bothmer A, Robbiani DF, Di Virgilio M, Bunting SF, Klein IA, Feldhahn N, Barlow J, Chen HT, Bosque D, Callen E, Nussenzweig A, Nussenzweig MC.

Mol Cell. 2011 May 6;42(3):319-29. doi: 10.1016/j.molcel.2011.03.019.


Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.

Santos MA, Huen MS, Jankovic M, Chen HT, López-Contreras AJ, Klein IA, Wong N, Barbancho JL, Fernandez-Capetillo O, Nussenzweig MC, Chen J, Nussenzweig A.

J Exp Med. 2010 May 10;207(5):973-81. doi: 10.1084/jem.20092308. Epub 2010 Apr 12.


AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.

Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC.

Mol Cell. 2009 Nov 25;36(4):631-41. doi: 10.1016/j.molcel.2009.11.007.


Rag mutations reveal robust alternative end joining.

Corneo B, Wendland RL, Deriano L, Cui X, Klein IA, Wong SY, Arnal S, Holub AJ, Weller GR, Pancake BA, Shah S, Brandt VL, Meek K, Roth DB.

Nature. 2007 Sep 27;449(7161):483-6.


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