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Items: 1 to 50 of 69

1.

Recognition for Discoveries in DNA Repair.

Klein HL, Symington LS.

N Engl J Med. 2019 Aug 15;381(7):677-679. doi: 10.1056/NEJMcibr1907358. No abstract available.

PMID:
31412183
2.

Genome instability consequences of RNase H2 Aicardi-Goutières syndrome alleles.

Potenski CJ, Epshtein A, Bianco C, Klein HL.

DNA Repair (Amst). 2019 Dec;84:102614. doi: 10.1016/j.dnarep.2019.04.002. Epub 2019 Apr 4.

PMID:
30975634
3.

Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.

Klein HL, Ang KKH, Arkin MR, Beckwitt EC, Chang YH, Fan J, Kwon Y, Morten MJ, Mukherjee S, Pambos OJ, El Sayyed H, Thrall ES, Vieira-da-Rocha JP, Wang Q, Wang S, Yeh HY, Biteen JS, Chi P, Heyer WD, Kapanidis AN, Loparo JJ, Strick TR, Sung P, Van Houten B, Niu H, Rothenberg E.

Microb Cell. 2019 Jan 7;6(1):65-101. doi: 10.15698/mic2019.01.665. Review.

4.

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways.

Klein HL, Bačinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A.

Microb Cell. 2019 Jan 7;6(1):1-64. doi: 10.15698/mic2019.01.664. Review.

5.

Genome instabilities arising from ribonucleotides in DNA.

Klein HL.

DNA Repair (Amst). 2017 Aug;56:26-32. doi: 10.1016/j.dnarep.2017.06.004. Epub 2017 Jun 9. Review.

7.

Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.

Niu H, Klein HL.

FEMS Yeast Res. 2017 Mar 1;17(2). doi: 10.1093/femsyr/fow111. Review.

8.

Roles of DNA helicases and Exo1 in the avoidance of mutations induced by Top1-mediated cleavage at ribonucleotides in DNA.

Niu H, Potenski CJ, Epshtein A, Sung P, Klein HL.

Cell Cycle. 2016;15(3):331-6. doi: 10.1080/15384101.2015.1128594. Epub 2015 Dec 30.

9.

Ribonucleotides in DNA: hidden in plain sight.

Jinks-Robertson S, Klein HL.

Nat Struct Mol Biol. 2015 Mar;22(3):176-8. doi: 10.1038/nsmb.2981. No abstract available.

PMID:
25736085
10.

How the misincorporation of ribonucleotides into genomic DNA can be both harmful and helpful to cells.

Potenski CJ, Klein HL.

Nucleic Acids Res. 2014;42(16):10226-34. doi: 10.1093/nar/gku773. Epub 2014 Aug 26. Review.

11.

Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms.

Potenski CJ, Niu H, Sung P, Klein HL.

Nature. 2014 Jul 10;511(7508):251-4. doi: 10.1038/nature13292. Epub 2014 Jun 1.

12.

Characterization of the interaction between the Saccharomyces cerevisiae Rad51 recombinase and the DNA translocase Rdh54.

Santa Maria SR, Kwon Y, Sung P, Klein HL.

J Biol Chem. 2013 Jul 26;288(30):21999-2005. doi: 10.1074/jbc.M113.480475. Epub 2013 Jun 24.

13.

Death becomes her: FBH1, DNA damage and apoptosis.

Potenski CJ, Klein HL.

Cell Cycle. 2013 May 1;12(9):1336-7. doi: 10.4161/cc.24668. Epub 2013 Apr 15. No abstract available.

14.

Sgs1--the maestro of recombination.

Klein HL, Symington LS.

Cell. 2012 Apr 13;149(2):257-9. doi: 10.1016/j.cell.2012.03.020.

15.

R we there yet? R-loop hazards to finishing the journey.

Potenski CJ, Klein HL.

Mol Cell. 2011 Dec 23;44(6):848-50. doi: 10.1016/j.molcel.2011.12.003.

16.

The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity.

Hoot SJ, Zheng X, Potenski CJ, White TC, Klein HL.

BMC Microbiol. 2011 Sep 27;11:214. doi: 10.1186/1471-2180-11-214.

17.

Methods to study mitotic homologous recombination and genome stability.

Zheng X, Epstein A, Klein HL.

Methods Mol Biol. 2011;745:3-13. doi: 10.1007/978-1-61779-129-1_1.

PMID:
21660685
18.

Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like factors.

Chi P, Kwon Y, Visnapuu ML, Lam I, Santa Maria SR, Zheng X, Epshtein A, Greene EC, Sung P, Klein HL.

Nucleic Acids Res. 2011 Aug;39(15):6511-22. doi: 10.1093/nar/gkr297. Epub 2011 May 9.

19.

Molecular biology: The expanding arena of DNA repair.

Potenski CJ, Klein HL.

Nature. 2011 Mar 3;471(7336):48-9. doi: 10.1038/471048a. No abstract available.

PMID:
21368822
20.

Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth.

Shah PP, Zheng X, Epshtein A, Carey JN, Bishop DK, Klein HL.

Mol Cell. 2010 Sep 24;39(6):862-72. doi: 10.1016/j.molcel.2010.08.028.

21.

Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repair.

Saponaro M, Callahan D, Zheng X, Krejci L, Haber JE, Klein HL, Liberi G.

PLoS Genet. 2010 Feb 26;6(2):e1000858. doi: 10.1371/journal.pgen.1000858.

22.

Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption.

Colavito S, Macris-Kiss M, Seong C, Gleeson O, Greene EC, Klein HL, Krejci L, Sung P.

Nucleic Acids Res. 2009 Nov;37(20):6754-64. doi: 10.1093/nar/gkp748. Epub 2009 Sep 10. Erratum in: Nucleic Acids Res. 2012 Apr;40(8):3775.

23.

Breaking up just got easier to do.

Klein HL, Symington LS.

Cell. 2009 Jul 10;138(1):20-2. doi: 10.1016/j.cell.2009.06.039.

24.

Functional interactions of meiotic recombination factors Rdh54 and Dmc1.

Chi P, Kwon Y, Moses DN, Seong C, Sehorn MG, Singh AK, Tsubouchi H, Greene EC, Klein HL, Sung P.

DNA Repair (Amst). 2009 Feb 1;8(2):279-84. doi: 10.1016/j.dnarep.2008.10.012. Epub 2008 Dec 9.

25.

Molecular biology: DNA endgames.

Klein HL.

Nature. 2008 Oct 9;455(7214):740-1. doi: 10.1038/455740a. No abstract available.

PMID:
18843352
26.

The consequences of Rad51 overexpression for normal and tumor cells.

Klein HL.

DNA Repair (Amst). 2008 May 3;7(5):686-93. doi: 10.1016/j.dnarep.2007.12.008. Epub 2008 Feb 1. Review.

27.

Reversal of fortune: Rad5 to the rescue.

Klein HL.

Mol Cell. 2007 Oct 26;28(2):181-3.

28.
29.

Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA.

Chi P, Kwon Y, Seong C, Epshtein A, Lam I, Sung P, Klein HL.

J Biol Chem. 2006 Sep 8;281(36):26268-79. Epub 2006 Jul 10.

30.
31.
32.

Effects of tumor-associated mutations on Rad54 functions.

Smirnova M, Van Komen S, Sung P, Klein HL.

J Biol Chem. 2004 Jun 4;279(23):24081-8. Epub 2004 Mar 31.

33.

Role of the error-free damage bypass postreplication repair pathway in the maintenance of genomic stability.

Smirnova M, Klein HL.

Mutat Res. 2003 Nov 27;532(1-2):117-35. Review.

PMID:
14643433
34.
35.

Replication, recombination, and repair: going for the gold.

Klein HL, Kreuzer KN.

Mol Cell. 2002 Mar;9(3):471-80.

37.
38.
40.

A radical solution to death.

Klein HL.

Nat Genet. 2000 Jun;25(2):132-4. No abstract available.

PMID:
10835619
41.
43.

Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.

Vainberg IE, Lewis SA, Rommelaere H, Ampe C, Vandekerckhove J, Klein HL, Cowan NJ.

Cell. 1998 May 29;93(5):863-73.

46.
47.
48.

Genetic control of intrachromosomal recombination.

Klein HL.

Bioessays. 1995 Feb;17(2):147-59. Review.

PMID:
7748165
49.

Examination of mitotic recombination by means of hyper-recombination mutants in Saccharomyces cerevisiae.

Klein HL.

Prog Nucleic Acid Res Mol Biol. 1995;51:271-303. Review. No abstract available.

PMID:
7659776

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