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Items: 50


The mortality burden of multidrug-resistant pathogens in India: a retrospective observational study.

Gandra S, Tseng KK, Arora A, Bhowmik B, Robinson ML, Panigrahi B, Laxminarayan R, Klein EY.

Clin Infect Dis. 2018 Nov 8. doi: 10.1093/cid/ciy955. [Epub ahead of print]


How frequently are hospitalized patients colonized with carbapenem-resistant Enterobacteriaceae (CRE) already on contact precautions for other indications?

Goodman KE, Simner PJ, Klein EY, Kazmi AQ, Gadala A, Rock C, Tamma PD, Cosgrove SE, Maragakis LL, Milstone AM; CDC Prevention Epicenters Program.

Infect Control Hosp Epidemiol. 2018 Oct 1:1-3. doi: 10.1017/ice.2018.236. [Epub ahead of print]


Reply to Abat et al.: Improved policies necessary to ensure an effective future for antibiotics.

Klein EY, Levin SA, Laxminarayan R.

Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8111-E8112. doi: 10.1073/pnas.1811245115. Epub 2018 Aug 7. No abstract available.


Temporal association between antibiotic use and resistance in Klebsiella pneumoniae at a tertiary care hospital.

Ryu S, Klein EY, Chun BC.

Antimicrob Resist Infect Control. 2018 Jul 16;7:83. doi: 10.1186/s13756-018-0373-6. eCollection 2018.


Emergency Department Utilization Among the Uninsured During Insurance Expansion in Maryland.

Xu T, Klein EY, Zhou M, Lowenthal J, Sharfstein JM, Peterson SM.

Ann Emerg Med. 2018 Aug;72(2):156-165. doi: 10.1016/j.annemergmed.2018.04.025. Epub 2018 Jun 7.


Patients' and Clinicians' Perceptions of Antibiotic Prescribing for Upper Respiratory Infections in the Acute Care Setting.

Broniatowski DA, Klein EY, May L, Martinez EM, Ware C, Reyna VF.

Med Decis Making. 2018 Jul;38(5):547-561. doi: 10.1177/0272989X18770664.


National Costs Associated with Methicillin-susceptible and Methicillin-resistant S. aureus Hospitalizations in the United States, 2010-2014.

Klein EY, Jiang W, Mojica N, Tseng KK, McNeill R, Cosgrove SE, Perl TM.

Clin Infect Dis. 2018 May 12. doi: 10.1093/cid/ciy399. [Epub ahead of print]


Temporal relationship between antibiotic use and respiratory virus activities in the Republic of Korea: a time-series analysis.

Ryu S, Kim S, Kim BI, Klein EY, Yoon YK, Chun BC.

Antimicrob Resist Infect Control. 2018 Apr 25;7:56. doi: 10.1186/s13756-018-0347-8. eCollection 2018.


Global increase and geographic convergence in antibiotic consumption between 2000 and 2015.

Klein EY, Van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin SA, Goossens H, Laxminarayan R.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3463-E3470. doi: 10.1073/pnas.1717295115. Epub 2018 Mar 26.


Reply to Arnold and Beavin.

Klein EY, Tseng K, Morgan DJ, Laxminarayan R.

Clin Infect Dis. 2018 Jul 2;67(2):320-322. doi: 10.1093/cid/ciy119. No abstract available.


Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics.

Klein EY, Blumenkrantz D, Serohijos A, Shakhnovich E, Choi JM, Rodrigues JV, Smith BD, Lane AP, Feldman A, Pekosz A.

mSphere. 2018 Jan 3;3(1). pii: e00554-17. doi: 10.1128/mSphereDirect.00554-17. eCollection 2018 Jan-Feb.


Trends in Methicillin-Resistant Staphylococcus aureus Hospitalizations in the United States, 2010-2014.

Klein EY, Mojica N, Jiang W, Cosgrove SE, Septimus E, Morgan DJ, Laxminarayan R.

Clin Infect Dis. 2017 Nov 13;65(11):1921-1923. doi: 10.1093/cid/cix640.


The Effect of Medicaid Expansion on Utilization in Maryland Emergency Departments.

Klein EY, Levin S, Toerper MF, Makowsky MD, Xu T, Cole G, Kelen GD.

Ann Emerg Med. 2017 Nov;70(5):607-614.e1. doi: 10.1016/j.annemergmed.2017.06.021. Epub 2017 Jul 24.


Categorical Risk Perception Drives Variability in Antibiotic Prescribing in the Emergency Department: A Mixed Methods Observational Study.

Klein EY, Martinez EM, May L, Saheed M, Reyna V, Broniatowski DA.

J Gen Intern Med. 2017 Oct;32(10):1083-1089. doi: 10.1007/s11606-017-4099-6. Epub 2017 Jun 20.


Is Antimicrobial Resistance a Bigger Problem in Tertiary Care Hospitals Than in Small Community Hospitals in the United States?

Gandra S, Trett A, Klein EY, Laxminarayan R.

Clin Infect Dis. 2017 Sep 1;65(5):860-863. doi: 10.1093/cid/cix413.


Risk of Acute Kidney Injury After Intravenous Contrast Media Administration.

Hinson JS, Ehmann MR, Fine DM, Fishman EK, Toerper MF, Rothman RE, Klein EY.

Ann Emerg Med. 2017 May;69(5):577-586.e4. doi: 10.1016/j.annemergmed.2016.11.021. Epub 2017 Jan 25.


Incidence and factors associated with emergency department visits for recurrent skin and soft tissue infections in patients in California, 2005-2011.

May L, Klein EY, Martinez EM, Mojica N, Miller LG.

Epidemiol Infect. 2017 Mar;145(4):746-754. doi: 10.1017/S0950268816002855. Epub 2016 Dec 5.


Multidrug- and Carbapenem-Resistant Pseudomonas aeruginosa in Children, United States, 1999-2012.

Logan LK, Gandra S, Mandal S, Klein EY, Levinson J, Weinstein RA, Laxminarayan R; Prevention Epicenters Program, US Centers for Disease Control and Prevention.

J Pediatric Infect Dis Soc. 2017 Nov 24;6(4):352-359. doi: 10.1093/jpids/piw064.


Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008-2014.

Gandra S, Mojica N, Klein EY, Ashok A, Nerurkar V, Kumari M, Ramesh U, Dey S, Vadwai V, Das BR, Laxminarayan R.

Int J Infect Dis. 2016 Sep;50:75-82. doi: 10.1016/j.ijid.2016.08.002. Epub 2016 Aug 10.


The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis.

Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, Dugas A.

Influenza Other Respir Viruses. 2016 Sep;10(5):394-403. doi: 10.1111/irv.12398. Epub 2016 Jun 24. Review.


Faropenem Consumption is Increasing in India.

Gandra S, Klein EY, Pant S, Malhotra-Kumar S, Laxminarayan R.

Clin Infect Dis. 2016 Apr 15;62(8):1050-2. doi: 10.1093/cid/ciw055. Epub 2016 Feb 7. No abstract available.


An Analysis of the Relationship Between the Heat Index and Arrivals in the Emergency Department.

Levy M, Broccoli M, Cole G, Jenkins JL, Klein EY.

PLoS Curr. 2015 Oct 29;7. pii: ecurrents.currents.dis.64546103ed4fa0bc7c5b779dd16f5358. doi: 10.1371/currents.dis.64546103ed4fa0bc7c5b779dd16f5358.


The impact of interruptions on the duration of nursing interventions: a direct observation study in an academic emergency department.

Cole G, Stefanus D, Gardner H, Levy MJ, Klein EY.

BMJ Qual Saf. 2016 Jun;25(6):457-65. doi: 10.1136/bmjqs-2014-003683. Epub 2015 Aug 20.


Bioeconomic analysis of child-targeted subsidies for artemisinin combination therapies: a cost-effectiveness analysis.

Klein EY, Smith DL, Cohen JM, Laxminarayan R.

J R Soc Interface. 2015 Jun 6;12(107). pii: 20141356. doi: 10.1098/rsif.2014.1356.


Influence of provider and urgent care density across different socioeconomic strata on outpatient antibiotic prescribing in the USA.

Klein EY, Makowsky M, Orlando M, Hatna E, Braykov NP, Laxminarayan R.

J Antimicrob Chemother. 2015 May;70(5):1580-7. doi: 10.1093/jac/dku563. Epub 2015 Jan 20.


Germs are germs, and why not take a risk? Patients' expectations for prescribing antibiotics in an inner-city emergency department.

Broniatowski DA, Klein EY, Reyna VF.

Med Decis Making. 2015 Jan;35(1):60-7. doi: 10.1177/0272989X14553472. Epub 2014 Oct 20.


The path of least resistance: aggressive or moderate treatment?

Kouyos RD, Metcalf CJ, Birger R, Klein EY, Abel zur Wiesch P, Ankomah P, Arinaminpathy N, Bogich TL, Bonhoeffer S, Brower C, Chi-Johnston G, Cohen T, Day T, Greenhouse B, Huijben S, Metlay J, Mideo N, Pollitt LC, Read AF, Smith DL, Standley C, Wale N, Grenfell B.

Proc Biol Sci. 2014 Nov 7;281(1794):20140566. doi: 10.1098/rspb.2014.0566.


Multisite exploration of clinical decision making for antibiotic use by emergency medicine providers using quantitative and qualitative methods.

May L, Gudger G, Armstrong P, Brooks G, Hinds P, Bhat R, Moran GJ, Schwartz L, Cosgrove SE, Klein EY, Rothman RE, Rand C.

Infect Control Hosp Epidemiol. 2014 Sep;35(9):1114-25. doi: 10.1086/677637. Epub 2014 Jul 23.


Influenza A H1N1 pandemic strain evolution--divergence and the potential for antigenic drift variants.

Klein EY, Serohijos AW, Choi JM, Shakhnovich EI, Pekosz A.

PLoS One. 2014 Apr 3;9(4):e93632. doi: 10.1371/journal.pone.0093632. eCollection 2014.


Recasting the theory of mosquito-borne pathogen transmission dynamics and control.

Smith DL, Perkins TA, Reiner RC Jr, Barker CM, Niu T, Chaves LF, Ellis AM, George DB, Le Menach A, Pulliam JR, Bisanzio D, Buckee C, Chiyaka C, Cummings DA, Garcia AJ, Gatton ML, Gething PW, Hartley DM, Johnston G, Klein EY, Michael E, Lloyd AL, Pigott DM, Reisen WK, Ruktanonchai N, Singh BK, Stoller J, Tatem AJ, Kitron U, Godfray HC, Cohen JM, Hay SI, Scott TW.

Trans R Soc Trop Med Hyg. 2014 Apr;108(4):185-97. doi: 10.1093/trstmh/tru026. Epub 2014 Mar 3.


Trends in antibiotic resistance in coagulase-negative staphylococci in the United States, 1999 to 2012.

May L, Klein EY, Rothman RE, Laxminarayan R.

Antimicrob Agents Chemother. 2014;58(3):1404-9. doi: 10.1128/AAC.01908-13. Epub 2013 Dec 16.


Disease at the wildlife-livestock interface: acaricide use on domestic cattle does not prevent transmission of a tick-borne pathogen with multiple hosts.

Walker JG, Klein EY, Levin SA.

Vet Parasitol. 2014 Jan 31;199(3-4):206-14. doi: 10.1016/j.vetpar.2013.11.008. Epub 2013 Nov 21.


Cross-reactive immune responses as primary drivers of malaria chronicity.

Klein EY, Graham AL, Llinás M, Levin S.

Infect Immun. 2014 Jan;82(1):140-51. doi: 10.1128/IAI.00958-13. Epub 2013 Oct 14.


The impact of heterogeneous transmission on the establishment and spread of antimalarial drug resistance.

Klein EY.

J Theor Biol. 2014 Jan 7;340:177-85. doi: 10.1016/j.jtbi.2013.09.022. Epub 2013 Sep 25.


The potential impact of age and season on methicillin-resistant Staphylococcus aureus prevalence.

Klein EY, Laxminarayan R.

Future Microbiol. 2013 Jul;8(7):809-12. doi: 10.2217/fmb.13.65. No abstract available.


Policy resistance undermines superspreader vaccination strategies for influenza.

Wells CR, Klein EY, Bauch CT.

PLoS Comput Biol. 2013;9(3):e1002945. doi: 10.1371/journal.pcbi.1002945. Epub 2013 Mar 7.


The changing epidemiology of methicillin-resistant Staphylococcus aureus in the United States: a national observational study.

Klein EY, Sun L, Smith DL, Laxminarayan R.

Am J Epidemiol. 2013 Apr 1;177(7):666-74. doi: 10.1093/aje/kws273. Epub 2013 Feb 28.


A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970-2010.

Reiner RC Jr, Perkins TA, Barker CM, Niu T, Chaves LF, Ellis AM, George DB, Le Menach A, Pulliam JR, Bisanzio D, Buckee C, Chiyaka C, Cummings DA, Garcia AJ, Gatton ML, Gething PW, Hartley DM, Johnston G, Klein EY, Michael E, Lindsay SW, Lloyd AL, Pigott DM, Reisen WK, Ruktanonchai N, Singh BK, Tatem AJ, Kitron U, Hay SI, Scott TW, Smith DL.

J R Soc Interface. 2013 Feb 13;10(81):20120921. doi: 10.1098/rsif.2012.0921. Print 2013 Apr 6. Review.


Antimalarial drug resistance: a review of the biology and strategies to delay emergence and spread.

Klein EY.

Int J Antimicrob Agents. 2013 Apr;41(4):311-7. doi: 10.1016/j.ijantimicag.2012.12.007. Epub 2013 Feb 8. Review.


Trends in resistance to carbapenems and third-generation cephalosporins among clinical isolates of Klebsiella pneumoniae in the United States, 1999-2010.

Braykov NP, Eber MR, Klein EY, Morgan DJ, Laxminarayan R.

Infect Control Hosp Epidemiol. 2013 Mar;34(3):259-68. doi: 10.1086/669523. Epub 2013 Jan 23.


Superinfection and the evolution of resistance to antimalarial drugs.

Klein EY, Smith DL, Laxminarayan R, Levin S.

Proc Biol Sci. 2012 Sep 22;279(1743):3834-42. doi: 10.1098/rspb.2012.1064. Epub 2012 Jul 11.


Seasonality and temporal correlation between community antibiotic use and resistance in the United States.

Sun L, Klein EY, Laxminarayan R.

Clin Infect Dis. 2012 Sep;55(5):687-94. doi: 10.1093/cid/cis509. Epub 2012 Jul 1.


Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana.

Klein EY, Lewis IA, Jung C, Llinás M, Levin SA.

Malar J. 2012 Apr 6;11:110. doi: 10.1186/1475-2875-11-110.


Prereferral rectal artesunate for treatment of severe childhood malaria: a cost-effectiveness analysis.

Tozan Y, Klein EY, Darley S, Panicker R, Laxminarayan R, Breman JG.

Lancet. 2010 Dec 4;376(9756):1910-5. doi: 10.1016/S0140-6736(10)61460-2. Epub 2010 Nov 29.


Cost-effectiveness of "golden mustard" for treating vitamin A deficiency in India.

Chow J, Klein EY, Laxminarayan R.

PLoS One. 2010 Aug 10;5(8):e12046. doi: 10.1371/journal.pone.0012046.


Prospective strategies to delay the evolution of anti-malarial drug resistance: weighing the uncertainty.

Smith DL, Klein EY, McKenzie FE, Laxminarayan R.

Malar J. 2010 Jul 23;9:217. doi: 10.1186/1475-2875-9-217.


Should new antimalarial drugs be subsidized?

Laxminarayan R, Parry IW, Smith DL, Klein EY.

J Health Econ. 2010 May;29(3):445-56. doi: 10.1016/j.jhealeco.2010.03.002. Epub 2010 Mar 7.


Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populations.

Lawpoolsri S, Klein EY, Singhasivanon P, Yimsamran S, Thanyavanich N, Maneeboonyang W, Hungerford LL, Maguire JH, Smith DL.

Malar J. 2009 Jul 15;8:159. doi: 10.1186/1475-2875-8-159.


Global investments in TB control: economic benefits.

Laxminarayan R, Klein EY, Darley S, Adeyi O.

Health Aff (Millwood). 2009 Jul-Aug;28(4):w730-42. doi: 10.1377/hlthaff.28.4.w730. Epub 2009 Jun 30.


Clinically immune hosts as a refuge for drug-sensitive malaria parasites.

Klein EY, Smith DL, Boni MF, Laxminarayan R.

Malar J. 2008 Apr 25;7:67. doi: 10.1186/1475-2875-7-67.

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