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Items: 29

1.

Biosimilars: State of Clinical and Regulatory Science.

Klein AV, Wang J, Feagan BG, Omoto M.

J Pharm Pharm Sci. 2017;20(1):332-348. doi: 10.18433/J3VK90.

2.

Regulatory Decision Making in Canada-Exploring New Frontiers in Patient Involvement.

Klein AV, Hardy S, Lim R, Marshall DA.

Value Health. 2016 Sep - Oct;19(6):730-733. doi: 10.1016/j.jval.2016.03.1855. Epub 2016 May 6.

3.

Changes in pulse pressure variation and plethysmographic variability index caused by hypotension-inducing hemorrhage followed by volume replacement in isoflurane-anesthetized dogs.

Klein AV, Teixeira-Neto FJ, Garofalo NA, Lagos-Carvajal AP, Diniz MS, Becerra-Velásquez DR.

Am J Vet Res. 2016 Mar;77(3):280-7. doi: 10.2460/ajvr.77.3.280.

PMID:
26919599
4.

Adrenomedullin induces pulmonary vasodilation but does not attenuate pulmonary hypertension in a sheep model of acute pulmonary embolism.

Lagos-Carvajal AP, Teixeira-Neto FJ, Becerra-Velásquez DR, Diniz MS, Klein AV, Rocha TL, Dias-Junior CA.

Life Sci. 2015 Oct 15;139:139-44. doi: 10.1016/j.lfs.2015.08.013. Epub 2015 Aug 24.

PMID:
26316450
5.

The mechanisms underlying fructose-induced hypertension: a review.

Klein AV, Kiat H.

J Hypertens. 2015 May;33(5):912-20. doi: 10.1097/HJH.0000000000000551. Review.

6.

Detox diets for toxin elimination and weight management: a critical review of the evidence.

Klein AV, Kiat H.

J Hum Nutr Diet. 2015 Dec;28(6):675-86. doi: 10.1111/jhn.12286. Epub 2014 Dec 18. Review.

PMID:
25522674
7.

Effects of dexmedetomidine on pulse pressure variation changes induced by hemorrhage followed by volume replacement in isoflurane-anesthetized dogs.

Diniz MS, Teixeira-Neto FJ, Cândido TD, Zanuzzo FS, Teixeira LR, Klein AV, do Nascimento P Jr.

J Vet Emerg Crit Care (San Antonio). 2014 Nov-Dec;24(6):681-92. doi: 10.1111/vec.12246.

PMID:
25471643
8.

Short communication. The role of animal-sourced insulin in the treatment of type 1 diabetes and its availability.

Klein AV, Taylor E, Legaré C, Vu D, Griffiths E.

Chronic Dis Inj Can. 2014 Jul;34(2-3):169-70. English, French.

9.

Biosimilar monoclonal antibodies: A Canadian regulatory perspective on the assessment of clinically relevant differences and indication extrapolation.

Scott BJ, Klein AV, Wang J.

J Clin Pharmacol. 2015 Mar;55 Suppl 3:S123-32. doi: 10.1002/jcph.339. Epub 2014 Jun 26. Review.

PMID:
24965228
10.

A new toolkit for conducting clinical trials in rare disorders: will this dog hunt?

Peterson RG, Macleod SM, Klein AV.

J Popul Ther Clin Pharmacol. 2014;21(1):e79-80. Epub 2014 Feb 23. No abstract available.

PMID:
24671905
11.

Impaired awareness of hypoglycemia in a man with type 1 diabetes.

Plourde G, Klein AV, Dent R.

CMAJ. 2014 Jul 8;186(10):770-1. doi: 10.1503/cmaj.131391. Epub 2014 Feb 10. No abstract available.

12.

Facile preparation of mono-, di- and mixed-carboxylato platinum(IV) complexes for versatile anticancer prodrug design.

Zhang JZ, Bonnitcha P, Wexselblatt E, Klein AV, Najajreh Y, Gibson D, Hambley TW.

Chemistry. 2013 Jan 28;19(5):1672-6. doi: 10.1002/chem.201203159. Epub 2012 Dec 18.

PMID:
23255183
13.

Health Canada/BIOTECanada Summit on regulatory and clinical topics related to subsequent entry biologics (biosimilars), Ottawa, Canada, 14 May 2012.

Kay J, Feagan BG, Guirguis MS, Keystone EC, Klein AV, Lubiniecki AS, Mould DR, Nyarko KA, Ridgway AA, Trudeau ME, Wang J.

Biologicals. 2012 Nov;40(6):517-27. doi: 10.1016/j.biologicals.2012.09.010. Epub 2012 Oct 17.

14.

The first subsequent entry biologic authorized for market in Canada: the story of Omnitrope, a recombinant human growth hormone.

Klein AV.

Biologicals. 2011 Sep;39(5):278-81. doi: 10.1016/j.biologicals.2011.06.003. Epub 2011 Jul 23. Review.

15.

Platinum drug distribution in cancer cells and tumors.

Klein AV, Hambley TW.

Chem Rev. 2009 Oct;109(10):4911-20. doi: 10.1021/cr9001066. Review. No abstract available.

PMID:
19711978
16.

Immunomodulation of reparative processes in the skin with ribomunyl.

Bazarny VV, Valamina IE, Selyanina ON, Tikhonina EA, Beresneva OY, Klein AV, Isaikin AI.

Bull Exp Biol Med. 2007 Jun;143(6):718-9. English, Russian.

PMID:
18239809
17.

Use of Eprex in Canada.

Légaré C, Turner C, Klein AV.

CMAJ. 2004 Sep 14;171(6):552-3. No abstract available.

18.

[Potentialities of collapse therapy in the treatment of destructive pulmonary tuberculosis].

Sokolov VA, Kil'kdiusheva EI, Egorov EA, Zhigalova NA, Sokolov VIu, Kleĭn AV, Kostina GI, Fadina OV.

Probl Tuberk. 2002;(5):16-9. Russian. No abstract available.

PMID:
12164111
19.

[Gastric tuberculosis in the past and present].

Kazak TI, Gerasimov VB, Khudiakova EV, Kleĭn AV, Sorokina ND.

Probl Tuberk. 2001;(4):24-7. Russian.

PMID:
11523364
20.

[Differential diagnosis of lobar (regional, segmental) extent pulmonary tuberculosis].

Sokolov VA, Egorov EA, Krasnoborova SIu, Savel'ev AV, Kartashov VM, Popov VA, Kleĭn AV, Piven' AI.

Probl Tuberk. 1997;(6):18-9. Russian.

PMID:
9503923
21.

[Morphological features of tissue reactions in combined treatment of experimental tuberculosis induced by xenobiotics].

Pavlov VA, Kazak TI, Kleĭn AV, Nosova NA.

Probl Tuberk. 1995;(6):32-5. Russian.

PMID:
8524767
22.

[Blood cardioplegia method in 2 heart valve prosthesis surgery using artificial blood circulation].

Iakimov VB, Levit AL, Terent'eva ND, Kleĭn AV, Griuner AR.

Anesteziol Reanimatol. 1995 Jan-Feb;(1):31-4. Russian. No abstract available.

PMID:
7605031
23.

Standards of aerosol therapy.

Klein AV, Roufail P.

CMAJ. 1993 Nov 1;149(9):1226. No abstract available.

24.

[The multistage surgical treatment of multiple spontaneous arterial aneurysms].

Ermolaev VL, Burleva EP, Kleĭn AV.

Vestn Khir Im I I Grek. 1992 Nov-Dec;149(11-12):340-2. Russian. No abstract available.

PMID:
8594794
25.

[Lipid peroxidation and the status of the basal membrane of the acinar cells in the minor salivary glands of patients with Sjögren's syndrome].

Ron' GI, Shmeleva LT, Klein AV, Iashkova EIu.

Stomatologiia (Mosk). 1992 Mar-Apr;(2):23-6. Russian.

PMID:
1412534
26.

[Histologic characteristics of the gastric and duodenal mucosa in post-vagotomy complications].

Lirman AV, Lisovskaia TV, Medvedeva SIu, Kleĭn AV.

Klin Med (Mosk). 1988 Oct;66(10):102-6. Russian. No abstract available.

PMID:
3236766
27.

[Clinico-pathomorphologic correlations in parkinsonism].

Starikov AS, Obraztsova RG, Kleĭn AV.

Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(12):28-32. Russian. No abstract available.

PMID:
6762023
28.

[Cortico-visceral relations in epilepsy].

Shefer DG, Beĭn BN, Kleĭn AV.

Sov Med. 1978 Jul;(7):145-6. Russian. No abstract available.

PMID:
694560
29.

[Temporal lobe epilepsy with polymorphic pathohistologic changes in the epileptogenic focus].

Beĭn BN, Kleĭn AV.

Zh Nevropatol Psikhiatr Im S S Korsakova. 1973;73(11):1689-92. Russian. No abstract available.

PMID:
4778241

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