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Multicenter External Validation of the Liverpool Uveal Melanoma Prognosticator Online: An OOG Collaborative Study.

Cunha Rola A, Taktak A, Eleuteri A, Kalirai H, Heimann H, Hussain R, Bonnett LJ, Hill CJ, Traynor M, Jager MJ, Marinkovic M, Luyten GPM, Dogrusöz M, Kilic E, de Klein A, Smit K, van Poppelen NM, Damato BE, Afshar A, Guthoff RF, Scheef BO, Kakkassery V, Saakyan S, Tsygankov A, Mosci C, Ligorio P, Viaggi S, Le Guin CHD, Bornfeld N, Bechrakis NE, Coupland SE.

Cancers (Basel). 2020 Feb 18;12(2). pii: E477. doi: 10.3390/cancers12020477.


A Metabolic Pathway for Activation of Dietary Glucosinolates by a Human Gut Symbiont.

Liou CS, Sirk SJ, Diaz CAC, Klein AP, Fischer CR, Higginbottom SK, Erez A, Donia MS, Sonnenburg JL, Sattely ES.

Cell. 2020 Feb 20;180(4):717-728.e19. doi: 10.1016/j.cell.2020.01.023.


Put a Strain on Secondary Mitral Regurgitation: Functional or Dysfunctional?

Klein AL, Wang TKM, Popović ZB.

J Am Coll Cardiol. 2020 Feb 25;75(7):759-762. doi: 10.1016/j.jacc.2019.12.025. No abstract available.


MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling.

Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, Prives C, Stockwell BR.

Genes Dev. 2020 Feb 20. doi: 10.1101/gad.334219.119. [Epub ahead of print]


Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin.

Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P.

J Nat Prod. 2020 Feb 20. doi: 10.1021/acs.jnatprod.9b01061. [Epub ahead of print]


Case series, contemporary review and imaging guided diagnostic and management approach of congenital pericardial defects.

Khayata M, Alkharabsheh S, Shah NP, Verma BR, Gentry JL, Summers M, Xu B, Asher C, Klein AL.

Open Heart. 2020 Jan 8;7(1):e001103. doi: 10.1136/openhrt-2019-001103. eCollection 2020.


Evaluating the effectiveness of retention forestry to enhance biodiversity in production forests of Central Europe using an interdisciplinary, multi-scale approach.

Storch I, Penner J, Asbeck T, Basile M, Bauhus J, Braunisch V, Dormann CF, Frey J, Gärtner S, Hanewinkel M, Koch B, Klein AM, Kuss T, Pregernig M, Pyttel P, Reif A, Scherer-Lorenzen M, Segelbacher G, Schraml U, Staab M, Winkel G, Yousefpour R.

Ecol Evol. 2020 Jan 14;10(3):1489-1509. doi: 10.1002/ece3.6003. eCollection 2020 Feb.


Novel GAA Variants and Mosaicism in Pompe Disease Identified by Extended Analyses of Patients with an Incomplete DNA Diagnosis.

In 't Groen SLM, de Faria DOS, Iuliano A, van den Hout JMP, Douben H, Dijkhuizen T, Cassiman D, Witters P, Barba Romero MÁ, de Klein A, Somers-Bolman GM, Saris JJ, Hoefsloot LH, van der Ploeg AT, Bergsma AJ, Pijnappel WWMP.

Mol Ther Methods Clin Dev. 2020 Jan 13;17:337-348. doi: 10.1016/j.omtm.2019.12.016. eCollection 2020 Jun 12.


Social anxiety and perceptions of likeability by peers in children.

Baartmans JMD, van Steensel FJA, Mobach L, Lansu TAM, Bijsterbosch G, Verpaalen I, Rapee RM, Magson N, Bögels SM, Rinck M, Klein AM.

Br J Dev Psychol. 2020 Feb 16. doi: 10.1111/bjdp.12324. [Epub ahead of print]


Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism.

Potratz M, Zaeck L, Christen M, Te Kamp V, Klein A, Nolden T, Freuling CM, Müller T, Finke S.

Cells. 2020 Feb 11;9(2). pii: E412. doi: 10.3390/cells9020412.


Effect of Adding Vildagliptin to Insulin in Hemodialyzed Patients with Type 2 Diabetes: A Randomized Multicentric Prospective Study-The VILDDIAL Study.

Munch M, Meyer L, Hannedouche T, Kunz K, Alenabi F, Winiszewski P, Baltzinger P, Smagala A, Klein A, Dorey F, Fleury D, Verier-Mine O, Guerci B, Cridlig J, Borot S, Ducloux D, Meyer N, Chantrel F, Kessler L.

Diabetes Obes Metab. 2020 Feb 11. doi: 10.1111/dom.13988. [Epub ahead of print]


Solvent-Containing Closure Material Can Be Used to Prevent Follicular Penetration of Caffeine and Fluorescein Sodium Salt on Porcine Ear Skin.

Klein AL, Lubda M, Akbarzadeh Taghavi P, Lademann J, Beckers I, von Hagen J, Kolmar H, Patzelt A.

Skin Pharmacol Physiol. 2020 Feb 11:1-9. doi: 10.1159/000505839. [Epub ahead of print]


Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice.

Beck TF, Veenma D, Shchelochkov OA, Yu Z, Kim BJ, Zaveri HP, van Bever Y, Choi S, Douben H, Bertin TK, Patel PI, Lee B, Tibboel D, de Klein A, Stockton DW, Justice MJ, Scott DA.

Hum Mol Genet. 2020 Feb 4. pii: ddz307. doi: 10.1093/hmg/ddz307. [Epub ahead of print] No abstract available.


Effects of cuff size and position on the agreement between arterial blood pressure measured by Doppler ultrasound and through a dorsal pedal artery catheter in anesthetized cats.

Cerejo SA, Teixeira-Neto FJ, Garofalo NA, Pimenta EL, Zanuzzo FS, Klein AV.

Vet Anaesth Analg. 2019 Nov 20. pii: S1467-2987(19)30317-4. doi: 10.1016/j.vaa.2019.11.001. [Epub ahead of print]


Retinal haemangioblastomas in von Hippel-Lindau germline mutation carriers: progression, complications and treatment outcome.

Hajjaj A, van Overdam KA, Oldenburg RA, Koopmans AE, van den Ouweland AMW, de Klein A, Kiliç E.

Acta Ophthalmol. 2020 Jan 30. doi: 10.1111/aos.14360. [Epub ahead of print]


Are Children Scheduled for Ventilation Tubes Insertion Overweight? A Cohort of Israeli Children.

Klein A, Kraus O, Luria A, Ovnat Tamir S, Marom T.

Ann Otol Rhinol Laryngol. 2020 Jan 29:3489420903336. doi: 10.1177/0003489420903336. [Epub ahead of print]


Comparative whole corona fingerprinting and protein adsorption thermodynamics of PLGA and PCL nanoparticles in human serum.

Ndumiso M, Buchtová N, Husselmann L, Mohamed G, Klein A, Aucamp M, Canevet D, D'Souza S, Maphasa RE, Boury F, Dube A.

Colloids Surf B Biointerfaces. 2020 Jan 22;188:110816. doi: 10.1016/j.colsurfb.2020.110816. [Epub ahead of print]


Inter-Individual Nectar Chemistry Changes of Field Scabious, Knautia arvensis.

Venjakob C, Leonhardt S, Klein AM.

Insects. 2020 Jan 22;11(2). pii: E75. doi: 10.3390/insects11020075.


[Resection of soft tissue tumours : Pitfalls, typical complications and prevention strategies].

Dürr HR, Müller A, Klein A.

Orthopade. 2020 Feb;49(2):98-103. doi: 10.1007/s00132-020-03876-x. Review. German.


Lineage tracing on transcriptional landscapes links state to fate during differentiation.

Weinreb C, Rodriguez-Fraticelli A, Camargo FD, Klein AM.

Science. 2020 Feb 14;367(6479). pii: eaaw3381. doi: 10.1126/science.aaw3381. Epub 2020 Jan 23.


Further Evidence of Inadequate Quality in Lateral Flow Devices Commercially Offered for the Diagnosis of Rabies.

Klein A, Fahrion A, Finke S, Eyngor M, Novak S, Yakobson B, Ngoepe E, Phahladira B, Sabeta C, De Benedictis P, Gourlaouen M, Orciari LA, Yager PA, Gigante CM, Knowles MK, Fehlner-Gardiner C, Servat A, Cliquet F, Marston D, McElhinney LM, Johnson T, Fooks AR, Müller T, Freuling CM.

Trop Med Infect Dis. 2020 Jan 18;5(1). pii: E13. doi: 10.3390/tropicalmed5010013.


The effect of bleaching agents on the DNA analysis of bloodstains on different floor coverings.

Edler C, Krebs O, Gehl A, Palatzke K, Tiedemann N, Schröder AS, Klein A.

Int J Legal Med. 2020 Jan 20. doi: 10.1007/s00414-020-02250-y. [Epub ahead of print]


Recent trends in the incidence and survival of Stage 1A Pancreatic Cancer: A Surveillance, Epidemiology, and End Results analysis.

Blackford AL, Canto MI, Klein AP, Hruban RH, Goggins M.

J Natl Cancer Inst. 2020 Jan 20. pii: djaa004. doi: 10.1093/jnci/djaa004. [Epub ahead of print]


Specificity of Dysfunctional Beliefs in Children with Social Anxiety Disorder: Effects of Comorbidity.

Mobach L, Klein AM, Schniering CA, Hudson JL.

J Clin Child Adolesc Psychol. 2020 Jan 17:1-8. doi: 10.1080/15374416.2019.1697930. [Epub ahead of print]


Biologic Therapies in Polyarticular Juvenile Idiopathic Arthritis. Comparison of Long-Term Safety Data from the German BIKER Registry.

Klein A, Becker I, Minden K, Hospach A, Schwarz T, Foeldvari I, Huegle B, Borte M, Weller-Heinemann F, Dressler F, Kuemmerle-Deschner J, Oommen PT, Foell D, Trauzeddel R, Rietschel C, Horneff G.

ACR Open Rheumatol. 2020 Jan;2(1):37-47. doi: 10.1002/acr2.11091. Epub 2019 Nov 24.


Rare diseases in Chile: challenges and recommendations in universal health coverage context.

Encina G, Castillo-Laborde C, Lecaros JA, Dubois-Camacho K, Calderón JF, Aguilera X, Klein AD, Repetto GM.

Orphanet J Rare Dis. 2019 Dec 11;14(1):289. doi: 10.1186/s13023-019-1261-8.


Divergences and commonalities between the US opioid crisis and prescription medicine mis/use in West Africa.

Klein A, Patwardhan S, Loglo MGA.

Int J Drug Policy. 2020 Feb;76:102640. doi: 10.1016/j.drugpo.2019.102640. Epub 2020 Jan 10.


Imaging of Diastolic Dysfunction in Community-Based Epidemiological Studies and Randomized Controlled Trials of HFpEF.

Chetrit M, Cremer PC, Klein AL.

JACC Cardiovasc Imaging. 2020 Jan;13(1 Pt 2):310-326. doi: 10.1016/j.jcmg.2019.10.022. Review.


A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer.

Zhong J, Jermusyk A, Wu L, Hoskins JW, Collins I, Mocci E, Zhang M, Song L, Chung CC, Zhang T, Xiao W, Albanes D, Andreotti G, Arslan AA, Babic A, Bamlet WR, Beane-Freeman L, Berndt S, Borgida A, Bracci PM, Brais L, Brennan P, Bueno-de-Mesquita B, Buring J, Canzian F, Childs EJ, Cotterchio M, Du M, Duell EJ, Fuchs C, Gallinger S, Gaziano JM, Giles GG, Giovannucci E, Goggins M, Goodman GE, Goodman PJ, Haiman C, Hartge P, Hasan M, Helzlsouer KJ, Holly EA, Klein EA, Kogevinas M, Kurtz RJ, LeMarchand L, Malats N, Männistö S, Milne R, Neale RE, Ng K, Obazee O, Oberg AL, Orlow I, Patel AV, Peters U, Porta M, Rothman N, Scelo G, Sesso HD, Severi G, Sieri S, Silverman D, Sund M, Tjønneland A, Thornquist MD, Tobias GS, Trichopoulou A, Van Den Eeden SK, Visvanathan K, Wactawski-Wende J, Wentzensen N, White E, Yu H, Yuan C, Zeleniuch-Jacquotte A, Hoover R, Brown K, Kooperberg C, Risch HA, Jacobs EJ, Li D, Yu K, Shu XO, Chanock SJ, Wolpin BM, Stolzenberg-Solomon RZ, Chatterjee N, Klein AP, Smith JP, Kraft P, Shi J, Petersen GM, Zheng W, Amundadottir LT.

J Natl Cancer Inst. 2020 Jan 9. pii: djz246. doi: 10.1093/jnci/djz246. [Epub ahead of print]


Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species.

Halberstadt AL, Chatha M, Klein AK, Wallach J, Brandt SD.

Neuropharmacology. 2020 Jan 7;167:107933. doi: 10.1016/j.neuropharm.2019.107933. [Epub ahead of print]


Effectiveness of durvalumab versus chemotherapy in metastatic urothelial cancer: an observational, indirect comparison.

Nordstrom BL, Oguz M, Chu BC, Ouwens M, Arkenau HT, Klein AB.

J Comp Eff Res. 2020 Feb;9(3):191-199. doi: 10.2217/cer-2019-0163. Epub 2020 Jan 9.


The emergence of transcriptional identity in somatosensory neurons.

Sharma N, Flaherty K, Lezgiyeva K, Wagner DE, Klein AM, Ginty DD.

Nature. 2020 Jan;577(7790):392-398. doi: 10.1038/s41586-019-1900-1. Epub 2020 Jan 8.


Check for publication integrity before misconduct.

Grey A, Bolland MJ, Avenell A, Klein AA, Gunsalus CK.

Nature. 2020 Jan;577(7789):167-169. doi: 10.1038/d41586-019-03959-6. No abstract available.


International scientists formulate a roadmap for insect conservation and recovery.

Harvey JA, Heinen R, Armbrecht I, Basset Y, Baxter-Gilbert JH, Bezemer TM, Böhm M, Bommarco R, Borges PAV, Cardoso P, Clausnitzer V, Cornelisse T, Crone EE, Dicke M, Dijkstra KB, Dyer L, Ellers J, Fartmann T, Forister ML, Furlong MJ, Garcia-Aguayo A, Gerlach J, Gols R, Goulson D, Habel JC, Haddad NM, Hallmann CA, Henriques S, Herberstein ME, Hochkirch A, Hughes AC, Jepsen S, Jones TH, Kaydan BM, Kleijn D, Klein AM, Latty T, Leather SR, Lewis SM, Lister BC, Losey JE, Lowe EC, Macadam CR, Montoya-Lerma J, Nagano CD, Ogan S, Orr MC, Painting CJ, Pham TH, Potts SG, Rauf A, Roslin TL, Samways MJ, Sanchez-Bayo F, Sar SA, Schultz CB, Soares AO, Thancharoen A, Tscharntke T, Tylianakis JM, Umbers KDL, Vet LEM, Visser ME, Vujic A, Wagner DL, WallisDeVries MF, Westphal C, White TE, Wilkins VL, Williams PH, Wyckhuys KAG, Zhu ZR, de Kroon H.

Nat Ecol Evol. 2020 Feb;4(2):174-176. doi: 10.1038/s41559-019-1079-8. No abstract available.


Strategies to minimize intraoperative blood loss during major surgery.

Shah A, Palmer AJR, Klein AA.

Br J Surg. 2020 Jan;107(2):e26-e38. doi: 10.1002/bjs.11393. Review.


Perioperative care and collaboration between surgeons and anaesthetists - it's about time.

Klein AA, Earnshaw JJ.

Br J Surg. 2020 Jan;107(2):e6-e7. doi: 10.1002/bjs.11445. No abstract available.


Peri-operative care and collaboration between surgeons and anaesthetists - it's about time.

Klein AA, Earnshaw JJ.

Anaesthesia. 2020 Jan;75 Suppl 1:e3-e4. doi: 10.1111/anae.14943. No abstract available.


Preoperative intravenous iron before cardiac surgery: a prospective multicentre feasibility study.

Klein AA, Chau M, Yeates JA, Collier T, Evans C, Agarwal S, Richards T; UK Cardiac and Vascular Surgery Interventional Anaemia Response (CAVIAR) study team.

Br J Anaesth. 2020 Mar;124(3):243-250. doi: 10.1016/j.bja.2019.11.023. Epub 2020 Jan 3.


Size-adjusted muscle power and muscle metabolism in patients with cystic fibrosis are equal to healthy controls - a case control study.

Ruf K, Beer M, Köstler H, Weng AM, Neubauer H, Klein A, Platek K, Roth K, Beneke R, Hebestreit H.

BMC Pulm Med. 2019 Dec 30;19(1):269. doi: 10.1186/s12890-019-1039-8.


Global longitudinal strain is a better metric than left ventricular ejection fraction: lessons learned from cancer therapeutic-related cardiac dysfunction.

Patel J, Rikhi R, Hussain M, Ayoub C, Klein A, Collier P, Moudgil R.

Curr Opin Cardiol. 2020 Mar;35(2):170-177. doi: 10.1097/HCO.0000000000000716.


Long-term surveillance of biologic therapies in systemic-onset juvenile idiopathic arthritis: data from the German BIKER registry.

Klein A, Klotsche J, Hügle B, Minden K, Hospach A, Weller-Heinemann F, Schwarz T, Dressler F, Trauzeddel R, Hufnagel M, Foeldvari I, Borte M, Kuemmerle-Deschner J, Brunner J, Oommen PT, Föll D, Tenbrock K, Urban A, Horneff G.

Rheumatology (Oxford). 2019 Dec 17. pii: kez577. doi: 10.1093/rheumatology/kez577. [Epub ahead of print]


Clinical utility of the Quantra® point-of-care haemostasis analyser during urgent cardiac surgery.

Zghaibe W, Scheuermann S, Munting K, Blaudszun G, Besser M, Ortmann E, Klein AA.

Anaesthesia. 2020 Mar;75(3):366-373. doi: 10.1111/anae.14942. Epub 2019 Dec 17.


Perioperative Complications Associated with Severity of Anemia in Geriatric Patients Undergoing Spinal Procedures.

Almeida ND, Lee R, Bestourous D, Klein AL, Parekh NR, Sack K, Sherman JH.

World Neurosurg. 2019 Dec 10. pii: S1878-8750(19)33009-8. doi: 10.1016/j.wneu.2019.11.159. [Epub ahead of print]


Exposure to radial extracorporeal shockwaves induces muscle regeneration after muscle injury in a surgical rat model.

Langendorf EK, Klein A, Drees P, Rommens PM, Mattyasovszky SG, Ritz U.

J Orthop Res. 2019 Dec 16. doi: 10.1002/jor.24564. [Epub ahead of print]


Non-uniform sampling in quantitative assessment of heterogeneous solid-state NMR line shapes.

Burakova E, Vasa SK, Klein A, Linser R.

J Biomol NMR. 2020 Jan;74(1):71-82. doi: 10.1007/s10858-019-00291-z. Epub 2019 Dec 13.


A Quasi-Likelihood Approach to Assess Model Fit in Quadratic and Interaction SEM.

Büchner RD, Klein AG.

Multivariate Behav Res. 2019 Dec 11:1-18. doi: 10.1080/00273171.2019.1689349. [Epub ahead of print]


Key performance indicators are needed for polypectomy.

Klein A, Bourke MJ.

Lancet Gastroenterol Hepatol. 2020 Jan;5(1):6-8. doi: 10.1016/S2468-1253(19)30336-X. No abstract available.


A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY).

Green L, Roberts N, Cooper J, Field J, Gill R, Klein A, Agarwal S, Stanworth S, Johnston A, Monk V, O'Brien B.

Trials. 2019 Dec 9;20(1):684. doi: 10.1186/s13063-019-3759-8.


Long-term data with idebenone on respiratory function outcomes in patients with Duchenne muscular dystrophy.

Servais L, Straathof CSM, Schara U, Klein A, Leinonen M, Hasham S, Meier T, De Waele L, Gordish-Dressman H, McDonald CM, Mayer OH, Voit T, Mercuri E, Buyse GM; SYROS and CINRG DNHS Investigators.

Neuromuscul Disord. 2019 Nov 5. pii: S0960-8966(19)31164-2. doi: 10.1016/j.nmd.2019.10.008. [Epub ahead of print]


The Effects of Escalation of Respiratory Support and Prolonged Invasive Ventilation on Outcomes of Cardiac Surgical Patients: A Retrospective Cohort Study.

Zochios V, Chandan JS, Schultz MJ, Morris AC, Parhar KK, Giménez-Milà M, Gerrard C, Vuylsteke A, Klein AA.

J Cardiothorac Vasc Anesth. 2019 Nov 8. pii: S1053-0770(19)31129-2. doi: 10.1053/j.jvca.2019.10.052. [Epub ahead of print]

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